| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_09855 | | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase | insig. | 100 | 100 |
| o | Pectobacterium carotovorum WPP14 | HER17_RS15550 | | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase | insig. | 45 | 95 |
| o | Dickeya dianthicola 67-19 | HGI48_RS05965 | | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase | insig. | 44 | 95 |
| o | Dickeya dianthicola ME23 | DZA65_RS06300 | | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase | cofit | 44 | 95 |
| o | Dickeya dadantii 3937 | DDA3937_RS05920 | | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase | insig. | 43 | 95 |
| o | Serratia liquefaciens MT49 | IAI46_17555 | | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase | insig. | 45 | 90 |
| o | Rahnella sp. WP5 | EX31_RS19350 | | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase | insig. | 44 | 94 |
| o | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF1869 | | 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate synthase (EC 4.2.99.20) | insig. | 44 | 89 |
| o | Klebsiella pneumoniae MKP103 | KDGMDA_26985 | | 2-succinyl-6-hydroxy-2 4-cyclohexadiene-1-carboxylate synthase | insig. | 43 | 89 |
| o | Escherichia coli ECOR27 | NOLOHH_14565 | menH | 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxy late synthase | insig. | 44 | 88 |
| o | Escherichia coli ECRC62 | BNILDI_13480 | menH | 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxy late synthase | cofit | 44 | 88 |
| o | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_01447 | | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase | insig. | 43 | 88 |
| o | Escherichia coli ECRC100 | OKFHMN_22940 | menH | 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxy late synthase | insig. | 43 | 88 |
| o | Escherichia coli ECRC101 | MCAODC_13980 | menH | 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxy late synthase | insig. | 43 | 88 |
| o | Escherichia coli ECRC102 | NIAGMN_20710 | menH | 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxy late synthase | insig. | 43 | 88 |
| o | Escherichia coli ECRC98 | JDDGAC_26905 | menH | 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxy late synthase | insig. | 43 | 88 |
| o | Escherichia coli ECRC99 | KEDOAH_05255 | menH | 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxy late synthase | no data | 43 | 88 |
| o | Klebsiella pneumoniae MRSN742743 | KFA93_RS06170 | menH;go_function=2-succinyl-6-hydroxy-2%2C4-cyclohexadiene-1-carboxylate | 2-succinyl-6-hydroxy-2 4-cyclohexadiene-1-carboxylate synthase | insig. | 42 | 89 |
| o | Escherichia coli BL21 | ECD_02190 | | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase | insig. | 43 | 88 |
| o | Escherichia coli BW25113 | b2263 | yfbB | predicted peptidase (NCBI) | sig. | 43 | 88 |
| o | Escherichia fergusonii Becca | EFB2_01592 | | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase | insig. | 43 | 88 |
| o | Escherichia coli ECOR38 | HEPCGN_22155 | menH | 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxy late synthase | insig. | 44 | 88 |
| o | Escherichia coli Nissle 1917 | ECOLIN_RS13180 | | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase | no data | 43 | 88 |
| o | Erwinia tracheiphila HP pepo 2.2 | IJEDHG_18175 | menH | 2-succinyl-6-hydroxy-2 4-cyclohexadiene-1-carboxylate synthase | cofit | 39 | 94 |
| o | Erwinia tracheiphila SCR3 | LU632_RS08110 | menH | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase | insig. | 39 | 94 |
| o | Klebsiella michiganensis M5al | BWI76_RS20070 | | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase | no data | 41 | 89 |
| o | Enterobacter sp. TBS_079 | MPMX20_03199 | | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase | insig. | 42 | 90 |
| o | Enterobacter asburiae PDN3 | EX28DRAFT_0341 | | 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase | insig. | 40 | 94 |
| o | Shewanella loihica PV-4 | Shew_3600 | | alpha/beta hydrolase fold (RefSeq) | cofit | 39 | 87 |
| o | Shewanella oneidensis MR-1 | SO4574 | | hydrolase, alpha/beta fold family (NCBI ptt file) | strong | 35 | 92 |
| o | Shewanella amazonensis SB2B | Sama_3461 | | alpha/beta fold family hydrolase (RefSeq) | strong | 35 | 93 |
| | Shewanella sp. ANA-3 | Shewana3_3966 | | alpha/beta hydrolase fold (RefSeq) | strong | 35 | 92 |
| | Pseudomonas sp. DMC3 | GFF2786 | | 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxy late synthase | cofit | 24 | 97 |
| | Synechococcus elongatus PCC 7942 | Synpcc7942_0774 | | esterase | strong | 27 | 92 |
| | Agrobacterium fabrum C58 | Atu2061 | | hydrolase | insig. | 24 | 98 |
| | Bosea sp. OAE506 | ABIE41_RS16255 | | alpha/beta fold hydrolase | insig. | 32 | 36 |
| | Variovorax sp. OAS795 | ABID97_RS21715 | | alpha/beta hydrolase | insig. | 23 | 95 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF278 | | Alpha/beta hydrolase fold | insig. | 24 | 96 |
| | Pseudomonas sp. S08-1 | OH686_12925 | | hypothetical protein | insig. | 25 | 87 |
| | Lysobacter sp. OAE881 | ABIE51_RS03110 | | alpha/beta hydrolase | cofit | 35 | 30 |
| | Synechococcus elongatus PCC 7942 | Synpcc7942_1801 | | hypothetical protein | insig. | 26 | 91 |
| | Phaeobacter inhibens DSM 17395 | PGA1_c11820 | | putative esterase | strong | 25 | 36 |
| | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_4205 | | Probable signal peptide protein | insig. | 34 | 37 |
| | Azospirillum sp. SherDot2 | MPMX19_03003 | | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase | no data | 32 | 35 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF3747 | | Alpha/beta hydrolase | no data | 27 | 88 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_28660 | | hydrolase | insig. | 24 | 92 |
| | Bosea sp. OAE506 | ABIE41_RS18950 | | alpha/beta hydrolase | insig. | 31 | 32 |
| | Bifidobacterium breve UCC2003 | BBR_RS14960 | | alpha/beta hydrolase | sig. | 22 | 92 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_29585 | | alpha/beta hydrolase | insig. | 23 | 91 |
| | Pseudomonas sp. BP01 | JOY50_RS13035 | | alpha/beta fold hydrolase | insig. | 37 | 31 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_02650 | | Pimeloyl-ACP methyl ester carboxylesterase | insig. | 33 | 33 |
| | Acinetobacter radioresistens SK82 | MPMX26_01739 | | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase | cofit | 29 | 35 |
| | Paraburkholderia graminis OAS925 | ABIE53_003140 | | acylglycerol lipase | insig. | 28 | 40 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF2240 | | Beta-ketoadipate enol-lactone hydrolase (EC 3.1.1.24) | insig. | 24 | 90 |
| | Pseudomonas sp. RS175 | PFR28_04671 | | hypothetical protein | insig. | 33 | 35 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_23160 | | hydrolase | insig. | 26 | 90 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS15355 | | alpha/beta hydrolase | insig. | 26 | 45 |
| | Acinetobacter baumannii LAC-4 | RR41_RS07485 | | alpha/beta hydrolase | insig. | 29 | 35 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS19710 | | hydrolase | insig. | 25 | 92 |
| | Pantoea agglomerans CFBP13505 P0401 | PagCFBP13505_RS03460 | | esterase | cofit | 31 | 37 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_5001 | | conserved hypothetical protein | insig. | 23 | 92 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_5001 | | conserved hypothetical protein | insig. | 23 | 92 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_3117 | | lipoprotein, putative | insig. | 37 | 31 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_3117 | | lipoprotein, putative | insig. | 37 | 31 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS17400 | | esterase | insig. | 33 | 32 |
| | Variovorax sp. OAS795 | ABID97_RS28985 | | alpha/beta hydrolase | sig. | 32 | 35 |
| | Rhodopseudomonas palustris CGA009 | TX73_010855 | | alpha/beta hydrolase | insig. | 30 | 33 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS04155 | | alpha/beta hydrolase | insig. | 28 | 39 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_4115 | | Probable signal peptide protein | insig. | 32 | 35 |
| | Dinoroseobacter shibae DFL-12 | Dshi_0536 | | biotin/lipoyl attachment domain-containing protein (RefSeq) | sig. | 38 | 32 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF1568 | | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase (EC 3.7.1.-) | no data | 31 | 44 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_02001 | | 2-(acetamidomethylene)succinate hydrolase | cofit | 25 | 97 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_1711 | | 2-hydroxymuconic semialdehyde hydrolase (EC 3.7.1.9) | insig. | 37 | 31 |
| | Dinoroseobacter shibae DFL-12 | Dshi_0820 | | alpha/beta hydrolase fold (RefSeq) | insig. | 28 | 37 |
| | Pseudomonas aeruginosa MRSN321 | DY961_RS17105 | | alpha/beta fold hydrolase | sig. | 31 | 34 |
| | Pseudomonas aeruginosa PUPa3 | DQ20_RS39360 | | alpha/beta fold hydrolase | insig. | 31 | 34 |