Conservation of cofitness between Pf1N1B4_1185 and Pf1N1B4_1474 in Pseudomonas fluorescens FW300-N1B4

59 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pseudomonas fluorescens FW300-N1B4 1.0 Pf1N1B4_1185 Lactate-responsive regulator LldR in Enterobacteria, GntR family 1.0 Pf1N1B4_1474 Glutamate-ammonia-ligase adenylyltransferase (EC 2.7.7.42) 0.59 5
Pseudomonas fluorescens GW456-L13 0.98 PfGW456L13_5113 Lactate-responsive regulator LldR in Enterobacteria, GntR family 0.95 PfGW456L13_213 Glutamate-ammonia-ligase adenylyltransferase (EC 2.7.7.42) low > 87
Pseudomonas fluorescens FW300-N2E3 0.95 AO353_05695 transcriptional regulator PdhR 0.92 AO353_12870 bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase 0.29 17
Pseudomonas fluorescens FW300-N2C3 0.95 AO356_07545 transcriptional regulator PdhR 0.87 AO356_08955 bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase 0.29 44
Pseudomonas fluorescens FW300-N2E2 0.94 Pf6N2E2_3379 Lactate-responsive regulator LldR in Enterobacteria, GntR family 0.89 Pf6N2E2_3672 Glutamate-ammonia-ligase adenylyltransferase (EC 2.7.7.42) 0.22 86
Pseudomonas fluorescens SBW25 0.94 PFLU_RS25940 FCD domain-containing protein 0.89 PFLU_RS02280 bifunctional [glutamate--ammonia ligase]-adenylyl-L-tyrosine phosphorylase/[glutamate--ammonia-ligase] adenylyltransferase low > 109
Pseudomonas fluorescens SBW25-INTG 0.94 PFLU_RS25940 FCD domain-containing protein 0.89 PFLU_RS02280 bifunctional [glutamate--ammonia ligase]-adenylyl-L-tyrosine phosphorylase/[glutamate--ammonia-ligase] adenylyltransferase low > 109
Pseudomonas sp. RS175 0.93 PFR28_00064 Pyruvate dehydrogenase complex repressor 0.87 PFR28_05062 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme low > 88
Pseudomonas simiae WCS417 0.89 PS417_24100 transcriptional regulator PdhR 0.89 PS417_02225 bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase low > 88
Pseudomonas putida KT2440 0.86 PP_4734 DNA-binding transcriptional dual regulator, LldR-L-lactate 0.78 PP_0340 Glutamate-ammonia-ligase adenylyltransferase 0.15 95
Pseudomonas sp. S08-1 0.79 OH686_17020 Lactate-responsive regulator LldR in Enterobacteria, GntR family 0.77 OH686_09700 Glutamine synthetase adenylyl-L-tyrosine phosphorylase / Glutamate-ammonia-ligase adenylyltransferase low > 80
Pseudomonas stutzeri RCH2 0.79 Psest_0956 Transcriptional regulators 0.77 Psest_0449 Glutamine synthetase adenylyltransferase low > 67
Marinobacter adhaerens HP15 0.64 HP15_4087 transcriptional regulator, GntR family 0.49 HP15_435 glutamate-ammonia-ligase adenylyltransferase 0.46 12
Enterobacter asburiae PDN3 0.43 EX28DRAFT_3708 Transcriptional regulators 0.40 EX28DRAFT_3081 Glutamine synthetase adenylyltransferase low > 76
Enterobacter sp. TBS_079 0.43 MPMX20_00806 Pyruvate dehydrogenase complex repressor 0.40 MPMX20_03890 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme 0.22 77
Klebsiella michiganensis M5al 0.42 BWI76_RS04875 transcriptional regulator PdhR 0.39 BWI76_RS24460 bifunctional glutamine synthetase adenylyltransferase/deadenyltransferase low > 92
Escherichia coli ECRC98 0.42 JDDGAC_14105 pdhR pyruvate dehydrogenase complex transcriptional repressor PdhR 0.39 JDDGAC_22365 glnE bifunctional [glutamate--ammonia ligase]-adenylyl-L-tyrosine phosphorylase/[glutamate--ammonia-ligase] adenylyltransferase low > 86
Escherichia fergusonii Becca 0.42 EFB2_03932 Pyruvate dehydrogenase complex repressor 0.39 EFB2_00758 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme low > 86
Escherichia coli HS(pFamp)R (ATCC 700891) 0.42 OHPLBJKB_03548 Pyruvate dehydrogenase complex repressor 0.39 OHPLBJKB_00651 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme low > 73
Escherichia coli BW25113 0.42 b0113 pdhR transcriptional regulator of pyruvate dehydrogenase complex (NCBI) 0.39 b3053 glnE fused deadenylyltransferase/adenylyltransferase for glutamine synthetase (NCBI) low > 76
Escherichia coli ECRC101 0.42 MCAODC_01025 pdhR pyruvate dehydrogenase complex transcriptional repressor PdhR 0.39 MCAODC_09245 glnE bifunctional [glutamate--ammonia ligase]-adenylyl-L-tyrosine phosphorylase/[glutamate--ammonia-ligase] adenylyltransferase low > 87
Escherichia coli ECOR38 0.42 HEPCGN_08490 pdhR pyruvate dehydrogenase complex transcriptional repressor PdhR 0.39 HEPCGN_17585 glnE bifunctional [glutamate--ammonia ligase]-adenylyl-L-tyrosine phosphorylase/[glutamate--ammonia-ligase] adenylyltransferase low > 87
Escherichia coli ECRC102 0.42 NIAGMN_08360 pdhR pyruvate dehydrogenase complex transcriptional repressor PdhR 0.39 NIAGMN_16495 glnE bifunctional [glutamate--ammonia ligase]-adenylyl-L-tyrosine phosphorylase/[glutamate--ammonia-ligase] adenylyltransferase — —
Escherichia coli Nissle 1917 0.42 ECOLIN_RS00635 pyruvate dehydrogenase complex transcriptional repressor PdhR 0.39 ECOLIN_RS17620 bifunctional [glutamate--ammonia ligase]-adenylyl-L-tyrosine phosphorylase/[glutamate--ammonia-ligase] adenylyltransferase low > 55
Escherichia coli ECOR27 0.42 NOLOHH_02855 pdhR pyruvate dehydrogenase complex transcriptional repressor PdhR 0.40 NOLOHH_10515 glnE bifunctional [glutamate--ammonia ligase]-adenylyl-L-tyrosine phosphorylase/[glutamate--ammonia-ligase] adenylyltransferase low > 75
Escherichia coli ECRC62 0.42 BNILDI_08755 pdhR pyruvate dehydrogenase complex transcriptional repressor PdhR 0.40 BNILDI_01000 glnE bifunctional [glutamate--ammonia ligase]-adenylyl-L-tyrosine phosphorylase/[glutamate--ammonia-ligase] adenylyltransferase low > 75
Escherichia coli ECRC99 0.42 KEDOAH_17645 pdhR pyruvate dehydrogenase complex transcriptional repressor PdhR 0.39 KEDOAH_09415 glnE bifunctional [glutamate--ammonia ligase]-adenylyl-L-tyrosine phosphorylase/[glutamate--ammonia-ligase] adenylyltransferase — —
Escherichia coli BL21 0.42 ECD_00112 pyruvate dehydrogenase complex repressor; autorepressor 0.39 ECD_02923 fused deadenylyltransferase/adenylyltransferase for glutamine synthetase low > 61
Escherichia coli ECRC100 0.42 OKFHMN_10510 pdhR pyruvate dehydrogenase complex transcriptional repressor PdhR 0.39 OKFHMN_18730 glnE bifunctional [glutamate--ammonia ligase]-adenylyl-L-tyrosine phosphorylase/[glutamate--ammonia-ligase] adenylyltransferase low > 80
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.42 GFF123 Transcriptional repressor for pyruvate dehydrogenase complex 0.39 GFF3167 Glutamate-ammonia-ligase adenylyltransferase (EC 2.7.7.42) low > 78
Shewanella oneidensis MR-1 0.42 SO0423 pdhR pyruvate dehydrogenase complex repressor (NCBI ptt file) 0.41 SO3760 glnE glutamate-ammonia-ligase adenylyltransferase (NCBI ptt file) low > 76
Shewanella sp. ANA-3 0.42 Shewana3_0425 pdhR transcriptional regulator PdhR (RefSeq) 0.42 Shewana3_0832 glutamate-ammonia ligase adenylyltransferase (RefSeq) low > 73
Shewanella amazonensis SB2B 0.41 Sama_0374 pdhR transcriptional regulator PdhR (RefSeq) 0.40 Sama_2663 (glutamate--ammonia-ligase) adenylyltransferase (RefSeq) low > 62
Shewanella loihica PV-4 0.41 Shew_3432 pdhR transcriptional regulator PdhR (RefSeq) 0.41 Shew_0628 (glutamate--ammonia-ligase) adenylyltransferase (RefSeq) low > 60
Serratia liquefaciens MT49 0.41 IAI46_21330 pyruvate dehydrogenase complex transcriptional repressor PdhR 0.39 IAI46_22060 bifunctional [glutamate--ammonia ligase]-adenylyl-L-tyrosine phosphorylase/[glutamate--ammonia-ligase] adenylyltransferase low > 86
Dickeya dadantii 3937 0.41 DDA3937_RS17930 pyruvate dehydrogenase complex transcriptional repressor PdhR 0.40 DDA3937_RS17105 bifunctional [glutamate--ammonia ligase]-adenylyl-L-tyrosine phosphorylase/[glutamate--ammonia-ligase] adenylyltransferase low > 74
Dickeya dianthicola ME23 0.40 DZA65_RS19005 pyruvate dehydrogenase complex transcriptional repressor PdhR 0.40 DZA65_RS18240 bifunctional [glutamate--ammonia ligase]-adenylyl-L-tyrosine phosphorylase/[glutamate--ammonia-ligase] adenylyltransferase low > 75
Vibrio cholerae E7946 ATCC 55056 0.40 CSW01_12225 pyruvate dehydrogenase complex transcriptional repressor PdhR 0.41 CSW01_12345 [glutamate--ammonia-ligase] adenylyltransferase low > 62
Dickeya dianthicola 67-19 0.40 HGI48_RS17855 pyruvate dehydrogenase complex transcriptional repressor PdhR 0.39 HGI48_RS17155 bifunctional [glutamate--ammonia ligase]-adenylyl-L-tyrosine phosphorylase/[glutamate--ammonia-ligase] adenylyltransferase low > 71
Pectobacterium carotovorum WPP14 0.40 HER17_RS03285 pyruvate dehydrogenase complex transcriptional repressor PdhR 0.40 HER17_RS04035 bifunctional [glutamate--ammonia ligase]-adenylyl-L-tyrosine phosphorylase/[glutamate--ammonia-ligase] adenylyltransferase low > 75
Erwinia tracheiphila SCR3 0.40 LU632_RS03075 pdhR pyruvate dehydrogenase complex transcriptional repressor PdhR 0.39 LU632_RS20675 glnE bifunctional [glutamate--ammonia ligase]-adenylyl-L-tyrosine phosphorylase/[glutamate--ammonia-ligase] adenylyltransferase low > 74
Rahnella sp. WP5 0.39 EX31_RS03485 pyruvate dehydrogenase complex transcriptional repressor PdhR 0.41 EX31_RS08145 bifunctional [glutamate--ammonia ligase]-adenylyl-L-tyrosine phosphorylase/[glutamate--ammonia-ligase] adenylyltransferase low > 89
Pantoea sp. MT58 0.39 IAI47_15815 pyruvate dehydrogenase complex transcriptional repressor PdhR 0.39 IAI47_03100 bifunctional [glutamate--ammonia ligase]-adenylyl-L-tyrosine phosphorylase/[glutamate--ammonia-ligase] adenylyltransferase low > 76
Magnetospirillum magneticum AMB-1 0.39 AMB_RS01210 FCD domain-containing protein 0.21 AMB_RS13495 glutamine-synthetase adenylyltransferase — —
Dinoroseobacter shibae DFL-12 0.35 Dshi_3026 GntR domain protein (RefSeq) 0.16 Dshi_1775 (Glutamate--ammonia-ligase) adenylyltransferase (RefSeq) low > 64
Alteromonas macleodii MIT1002 0.35 MIT1002_03004 Pyruvate dehydrogenase complex repressor 0.34 MIT1002_02879 Glutamate-ammonia-ligase adenylyltransferase 0.55 39
Castellaniella sp019104865 MT123 0.35 ABCV34_RS10290 transcriptional regulator LldR 0.26 ABCV34_RS06200 bifunctional [glutamate--ammonia ligase]-adenylyl-L-tyrosine phosphorylase/[glutamate--ammonia-ligase] adenylyltransferase 0.39 28
Phaeobacter inhibens DSM 17395 0.34 PGA1_c00760 putative pyruvate dehydrogenase complex repressor 0.16 PGA1_c20010 glutamate-ammonia-ligase adenylyltransferase GlnE low > 62
Sinorhizobium meliloti 1021 0.34 SMc00829 transcriptional regulator 0.19 SMc02368 bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase low > 103
Azospirillum sp. SherDot2 0.32 MPMX19_06090 Pyruvate dehydrogenase complex repressor 0.19 MPMX19_01990 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme low > 112
Paraburkholderia sabiae LMG 24235 0.31 QEN71_RS38010 transcriptional regulator GlcC 0.29 QEN71_RS26540 bifunctional [glutamate--ammonia ligase]-adenylyl-L-tyrosine phosphorylase/[glutamate--ammonia-ligase] adenylyltransferase low > 153
Burkholderia phytofirmans PsJN 0.31 BPHYT_RS31640 GntR family transcriptional regulator 0.28 BPHYT_RS03555 glutamine-synthetase adenylyltransferase low > 109
Paraburkholderia bryophila 376MFSha3.1 0.31 H281DRAFT_02906 transcriptional regulator, GntR family 0.28 H281DRAFT_04691 glutamate-ammonia-ligase adenylyltransferase low > 103
Acinetobacter radioresistens SK82 0.30 MPMX26_02258 Putative L-lactate dehydrogenase operon regulatory protein 0.36 MPMX26_00444 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme low > 36
Cupriavidus basilensis FW507-4G11 0.30 RR42_RS21300 GntR family transcriptional regulator 0.30 RR42_RS05890 glutamine-synthetase adenylyltransferase low > 128
Variovorax sp. OAS795 0.19 ABID97_RS05820 FadR/GntR family transcriptional regulator 0.23 ABID97_RS02015 bifunctional [glutamate--ammonia ligase]-adenylyl-L-tyrosine phosphorylase/[glutamate--ammonia-ligase] adenylyltransferase low > 91
Caulobacter crescentus NA1000 0.19 CCNA_01037 GntR-family transcriptional regulator 0.15 CCNA_02839 glutamate-ammonia-ligase adenylyltransferase low > 66
Caulobacter crescentus NA1000 Δfur 0.19 CCNA_01037 GntR-family transcriptional regulator 0.15 CCNA_02839 glutamate-ammonia-ligase adenylyltransferase low > 67
Herbaspirillum seropedicae SmR1 0.19 HSERO_RS20270 transcription regulator protein 0.28 HSERO_RS07140 glutamine-synthetase adenylyltransferase — —
Rhizobium sp. OAE497 0.18 ABIE40_RS25825 FadR/GntR family transcriptional regulator 0.20 ABIE40_RS05710 bifunctional [glutamine synthetase] adenylyltransferase/[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase low > 107

Not shown: 8 genomes with orthologs for Pf1N1B4_1185 only; 20 genomes with orthologs for Pf1N1B4_1474 only