Conservation of cofitness between PP_5035 and PP_4782 in Pseudomonas putida KT2440

49 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pseudomonas putida KT2440 1.0 PP_5035 Histidine utilization repressor 1.0 PP_4782 Phosphomethylpyrimidine kinase 0.47 4
Pseudomonas syringae pv. syringae B728a 0.87 Psyr_0366 transcriptional regulator, GntR family 0.85 Psyr_4340 phosphomethylpyrimidine kinase, putative low > 86
Pseudomonas fluorescens GW456-L13 0.87 PfGW456L13_329 Histidine utilization repressor 0.87 PfGW456L13_1385 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) low > 87
Pseudomonas syringae pv. syringae B728a ΔmexB 0.87 Psyr_0366 transcriptional regulator, GntR family 0.85 Psyr_4340 phosphomethylpyrimidine kinase, putative low > 86
Pseudomonas fluorescens FW300-N2E3 0.87 AO353_12240 histidine utilization repressor 0.87 AO353_06350 hydrogenase low > 101
Pseudomonas fluorescens FW300-N1B4 0.87 Pf1N1B4_1590 Histidine utilization repressor 0.78 Pf1N1B4_2718 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) low > 87
Pseudomonas fluorescens FW300-N2C3 0.87 AO356_09640 histidine utilization repressor 0.88 AO356_15435 hydrogenase low > 104
Pseudomonas sp. RS175 0.87 PFR28_04963 HTH-type transcriptional repressor NagR 0.84 PFR28_03843 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 88
Pseudomonas fluorescens FW300-N2E2 0.86 Pf6N2E2_3807 Histidine utilization repressor 0.78 Pf6N2E2_5024 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) low > 103
Pseudomonas fluorescens SBW25-INTG 0.84 PFLU_RS01765 histidine utilization repressor 0.88 PFLU_RS26530 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 109
Pseudomonas fluorescens SBW25 0.84 PFLU_RS01765 histidine utilization repressor 0.88 PFLU_RS26530 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 109
Pseudomonas simiae WCS417 0.84 PS417_01710 histidine utilization repressor 0.87 PS417_24600 hydrogenase low > 88
Dickeya dianthicola ME23 0.63 DZA65_RS15850 histidine utilization repressor 0.22 DZA65_RS16235 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 75
Enterobacter sp. TBS_079 0.63 MPMX20_01398 HTH-type transcriptional repressor NagR 0.24 MPMX20_03076 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 85
Enterobacter asburiae PDN3 0.63 EX28DRAFT_2221 histidine utilization repressor, proteobacterial 0.22 EX28DRAFT_0469 hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 76
Dickeya dianthicola 67-19 0.63 HGI48_RS15100 histidine utilization repressor 0.22 HGI48_RS15410 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 71
Klebsiella michiganensis M5al 0.63 BWI76_RS08730 histidine utilization repressor 0.24 BWI76_RS19375 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 92
Dickeya dadantii 3937 0.62 DDA3937_RS15020 histidine utilization repressor 0.23 DDA3937_RS15335 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 74
Serratia liquefaciens MT49 0.62 IAI46_10615 histidine utilization repressor 0.24 IAI46_19100 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 86
Pantoea sp. MT58 0.62 IAI47_13270 histidine utilization repressor 0.20 IAI47_06810 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 76
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.60 GFF665 Histidine utilization repressor 0.23 GFF3834 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) low > 78
Rahnella sp. WP5 0.60 EX31_RS06725 histidine utilization repressor 0.23 EX31_RS20390 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 89
Rhizobium sp. OAE497 0.57 ABIE40_RS23900 histidine utilization repressor 0.27 ABIE40_RS25930 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 107
Sinorhizobium meliloti 1021 0.57 SMc00674 histidine utilization repressor transcription regulator protein 0.19 SM_b20962 phoshomethylpyrimidine kinase low > 103
Variovorax sp. SCN45 0.47 GFF6410 Histidine utilization repressor 0.16 GFF2149 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) low > 127
Variovorax sp. OAS795 0.47 ABID97_RS03415 histidine utilization repressor 0.19 ABID97_RS15330 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Cupriavidus basilensis FW507-4G11 0.47 RR42_RS16925 histidine utilization repressor 0.19 RR42_RS01370 phosphomethylpyrimidine kinase — —
Azospirillum sp. SherDot2 0.45 MPMX19_04937 Mannosyl-D-glycerate transport/metabolism system repressor MngR 0.21 MPMX19_06182 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase — —
Acidovorax sp. GW101-3H11 0.45 Ac3H11_2559 Histidine utilization repressor 0.21 Ac3H11_1063 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) — —
Paraburkholderia sabiae LMG 24235 0.44 QEN71_RS07755 histidine utilization repressor 0.19 QEN71_RS06305 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Paraburkholderia bryophila 376MFSha3.1 0.44 H281DRAFT_05296 GntR family transcriptional regulator, histidine utilization repressor 0.22 H281DRAFT_04811 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 103
Rhodospirillum rubrum S1H 0.44 Rru_A1294 Transcriptional Regulator, Histidine utilization repressor, GntR family (NCBI) 0.27 Rru_A1102 Phosphomethylpyrimidine kinase (NCBI) — —
Ralstonia sp. UNC404CL21Col 0.43 ABZR87_RS01035 histidine utilization repressor 0.24 ABZR87_RS04830 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Ralstonia solanacearum PSI07 0.43 RPSI07_RS11905 histidine utilization repressor 0.26 RPSI07_RS23455 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Burkholderia phytofirmans PsJN 0.43 BPHYT_RS07560 histidine utilization repressor 0.19 BPHYT_RS04205 kinase — —
Paraburkholderia graminis OAS925 0.43 ABIE53_001730 GntR family histidine utilization transcriptional repressor 0.22 ABIE53_001125 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 113
Ralstonia solanacearum IBSBF1503 0.43 RALBFv3_RS05400 histidine utilization repressor 0.26 RALBFv3_RS09905 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Ralstonia solanacearum UW163 0.43 UW163_RS08225 histidine utilization repressor 0.26 UW163_RS03675 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Ralstonia solanacearum GMI1000 0.42 RS_RS13260 histidine utilization repressor 0.26 RS_RS00495 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.42 GFF3591 Histidine utilization repressor 0.24 GFF249 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) low > 90
Pseudomonas sp. S08-1 0.41 OH686_16760 histidine utilization repressor 0.82 OH686_09185 Hydroxymethylpyrimidine phosphate kinase ThiD low > 80
Vibrio cholerae E7946 ATCC 55056 0.41 CSW01_06100 histidine utilization repressor 0.22 CSW01_06545 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.48 5
Castellaniella sp019104865 MT123 0.37 ABCV34_RS12825 histidine utilization repressor 0.22 ABCV34_RS14505 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Bosea sp. OAE506 0.34 ABIE41_RS23630 histidine utilization repressor 0.24 ABIE41_RS21620 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Caulobacter crescentus NA1000 0.29 CCNA_01013 histidine utilization repressor 0.23 CCNA_03331 phosphomethylpyrimidine kinase/hydroxymethylpyrimidine kinase — —
Caulobacter crescentus NA1000 Δfur 0.29 CCNA_01013 histidine utilization repressor 0.23 CCNA_03331 phosphomethylpyrimidine kinase/hydroxymethylpyrimidine kinase — —
Xanthomonas campestris pv. campestris strain 8004 0.26 Xcc-8004.3293.1 Histidine utilization repressor 0.23 Xcc-8004.3091.1 hypothetical protein low > 74
Sphingomonas koreensis DSMZ 15582 0.26 Ga0059261_3966 Transcriptional regulators 0.21 Ga0059261_1961 hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Brevundimonas sp. GW460-12-10-14-LB2 0.25 A4249_RS06610 histidine utilization repressor 0.24 A4249_RS15985 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Phaeobacter inhibens DSM 17395 0.18 PGA1_c36370 HTH-type transcriptional regulator, GntR family 0.17 PGA1_c09030 phosphomethylpyrimidine kinase ThiD low > 62

Not shown: 5 genomes with orthologs for PP_5035 only; 44 genomes with orthologs for PP_4782 only