Conservation of cofitness between HGI48_RS18515 and HGI48_RS19745 in Dickeya dianthicola 67-19

59 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Dickeya dianthicola 67-19 1.0 HGI48_RS18515 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 1.0 HGI48_RS19745 two-component system sensor histidine kinase EnvZ 0.75 1
Dickeya dianthicola ME23 0.99 DZA65_RS19650 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 0.99 DZA65_RS20835 two-component system sensor histidine kinase EnvZ low > 75
Dickeya dadantii 3937 0.97 DDA3937_RS18580 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 0.96 DDA3937_RS19615 two-component system sensor histidine kinase EnvZ low > 74
Pectobacterium carotovorum WPP14 0.88 HER17_RS02615 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 0.87 HER17_RS01705 two-component system sensor histidine kinase EnvZ low > 75
Serratia liquefaciens MT49 0.85 IAI46_01800 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 0.84 IAI46_23785 two-component system sensor histidine kinase EnvZ low > 86
Klebsiella michiganensis M5al 0.84 BWI76_RS02820 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 0.81 BWI76_RS26670 two-component sensor histidine kinase low > 92
Enterobacter sp. TBS_079 0.83 MPMX20_00515 UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl- meso-2,6-diaminoheptandioate ligase 0.82 MPMX20_04291 Osmolarity sensor protein EnvZ low > 85
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.83 GFF881 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase (EC 6.3.2.-) 0.82 GFF614 Osmolarity sensory histidine kinase EnvZ low > 78
Escherichia coli ECRC62 0.83 BNILDI_07315 mpl UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-me so-diaminopimelate ligase 0.81 BNILDI_02690 envZ two-component system sensor histidine kinase EnvZ low > 75
Escherichia coli ECOR27 0.83 NOLOHH_04200 mpl UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-me so-diaminopimelate ligase 0.81 NOLOHH_08830 envZ two-component system sensor histidine kinase EnvZ low > 75
Escherichia coli ECOR38 0.83 HEPCGN_10140 mpl UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-me so-diaminopimelate ligase 0.81 HEPCGN_15850 envZ two-component system sensor histidine kinase EnvZ low > 87
Escherichia coli ECRC98 0.83 JDDGAC_15580 mpl UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-me so-diaminopimelate ligase 0.81 JDDGAC_20670 envZ two-component system sensor histidine kinase EnvZ 0.93 23
Escherichia fergusonii Becca 0.83 EFB2_04300 UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl- meso-2,6-diaminoheptandioate ligase 0.81 EFB2_00424 Osmolarity sensor protein EnvZ low > 86
Escherichia coli ECRC99 0.83 KEDOAH_16215 mpl UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-me so-diaminopimelate ligase 0.81 KEDOAH_11100 envZ two-component system sensor histidine kinase EnvZ — —
Escherichia coli BL21 0.83 ECD_04101 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 0.81 ECD_03256 sensory histidine kinase in two-component regulatory system with OmpR low > 61
Escherichia coli ECRC100 0.83 OKFHMN_11940 mpl UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-me so-diaminopimelate ligase 0.81 OKFHMN_17040 envZ two-component system sensor histidine kinase EnvZ low > 80
Escherichia coli ECRC101 0.83 MCAODC_02445 mpl UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-me so-diaminopimelate ligase 0.81 MCAODC_07570 envZ two-component system sensor histidine kinase EnvZ low > 87
Escherichia coli HS(pFamp)R (ATCC 700891) 0.83 OHPLBJKB_03802 UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl- meso-2,6-diaminoheptandioate ligase 0.81 OHPLBJKB_00299 Osmolarity sensor protein EnvZ low > 73
Escherichia coli ECRC102 0.83 NIAGMN_09790 mpl UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-me so-diaminopimelate ligase 0.81 NIAGMN_14810 envZ two-component system sensor histidine kinase EnvZ — —
Escherichia coli BW25113 0.83 b4233 mpl UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase (NCBI) 0.81 b3404 envZ osmolarity sensor protein (NCBI) low > 76
Enterobacter asburiae PDN3 0.83 EX28DRAFT_3420 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase 0.82 EX28DRAFT_4139 Signal transduction histidine kinase low > 76
Escherichia coli Nissle 1917 0.83 ECOLIN_RS24560 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 0.81 ECOLIN_RS19450 two-component system sensor histidine kinase EnvZ low > 55
Rahnella sp. WP5 0.82 EX31_RS08665 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 0.85 EX31_RS04795 two-component system sensor histidine kinase EnvZ low > 89
Pantoea sp. MT58 0.80 IAI47_02755 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 0.83 IAI47_01825 two-component system sensor histidine kinase EnvZ low > 76
Erwinia tracheiphila SCR3 0.78 LU632_RS02135 mpl UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 0.79 LU632_RS22935 envZ two-component system sensor histidine kinase EnvZ low > 74
Vibrio cholerae E7946 ATCC 55056 0.67 CSW01_12875 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 0.47 CSW01_13690 two-component system sensor histidine kinase EnvZ low > 62
Shewanella sp. ANA-3 0.61 Shewana3_0791 UDP-N-acetylmuramate (RefSeq) 0.39 Shewana3_4018 envZ osmolarity sensor protein (RefSeq) low > 73
Shewanella oneidensis MR-1 0.61 SO3805 mpl UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase (NCBI ptt file) 0.38 SO4634 envZ osmolarity sensor protein EnvZ (NCBI ptt file) low > 76
Shewanella loihica PV-4 0.60 Shew_3144 UDP-N-acetylmuramate (RefSeq) 0.38 Shew_3638 envZ osmolarity sensor protein (RefSeq) low > 60
Shewanella amazonensis SB2B 0.59 Sama_0769 UDP-N-acetylmuramate (RefSeq) 0.36 Sama_3511 envZ osmolarity sensor protein (RefSeq) low > 62
Alteromonas macleodii MIT1002 0.59 MIT1002_00168 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 0.35 MIT1002_03969 Osmolarity sensor protein EnvZ 0.69 16
Pseudomonas simiae WCS417 0.58 PS417_24800 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 0.22 PS417_01175 ATPase — —
Ralstonia solanacearum PSI07 0.57 RPSI07_RS11275 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 0.17 RPSI07_RS16065 two-component sensor histidine kinase low > 81
Ralstonia solanacearum GMI1000 0.57 RS_RS13915 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 0.17 RS_RS08300 two-component sensor histidine kinase low > 80
Ralstonia solanacearum UW163 0.57 UW163_RS07655 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 0.18 UW163_RS14730 two-component sensor histidine kinase — —
Pseudomonas fluorescens SBW25-INTG 0.57 PFLU_RS26735 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 0.22 PFLU_RS01285 HAMP domain-containing protein 0.30 86
Pseudomonas putida KT2440 0.57 PP_0547 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 0.19 PP_0247 Osmolarity sensor protein EnvZ low > 96
Pseudomonas fluorescens SBW25 0.57 PFLU_RS26735 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 0.22 PFLU_RS01285 HAMP domain-containing protein low > 109
Ralstonia solanacearum IBSBF1503 0.57 RALBFv3_RS05970 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 0.18 RALBFv3_RS01420 two-component sensor histidine kinase low > 76
Pseudomonas fluorescens FW300-N2E3 0.57 AO353_06550 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 0.22 AO353_11750 ATPase low > 101
Pseudomonas fluorescens FW300-N2C3 0.57 AO356_15235 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 0.22 AO356_10165 ATPase low > 104
Pseudomonas sp. RS175 0.57 PFR28_03883 UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl- meso-2,6-diaminoheptandioate ligase 0.22 PFR28_04869 Osmolarity sensor protein EnvZ low > 88
Ralstonia sp. UNC404CL21Col 0.56 ABZR87_RS01630 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 0.17 ABZR87_RS13215 ATP-binding protein 0.29 78
Pseudomonas fluorescens GW456-L13 0.56 PfGW456L13_1344 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase (EC 6.3.2.-) 0.21 PfGW456L13_426 Osmolarity sensory histidine kinase EnvZ low > 87
Pseudomonas syringae pv. syringae B728a ΔmexB 0.56 Psyr_0630 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 0.23 Psyr_0259 Osmolarity sensor protein envZ — —
Pseudomonas syringae pv. syringae B728a 0.56 Psyr_0630 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 0.23 Psyr_0259 Osmolarity sensor protein envZ low > 86
Pseudomonas fluorescens FW300-N1B4 0.56 Pf1N1B4_2676 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase (EC 6.3.2.-) 0.22 Pf1N1B4_1773 Osmolarity sensory histidine kinase EnvZ — —
Pseudomonas fluorescens FW300-N2E2 0.56 Pf6N2E2_4982 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase (EC 6.3.2.-) 0.22 Pf6N2E2_3904 Osmolarity sensory histidine kinase EnvZ — —
Paraburkholderia sabiae LMG 24235 0.56 QEN71_RS27145 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 0.18 QEN71_RS25990 ATP-binding protein low > 153
Cupriavidus basilensis FW507-4G11 0.55 RR42_RS17675 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 0.18 RR42_RS07880 histidine kinase 0.39 38
Pseudomonas stutzeri RCH2 0.55 Psest_0673 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase 0.23 Psest_3994 Signal transduction histidine kinase low > 67
Paraburkholderia graminis OAS925 0.54 ABIE53_003563 UDP-N-acetylmuramate: L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase 0.19 ABIE53_004378 two-component system osmolarity sensor histidine kinase EnvZ low > 113
Burkholderia phytofirmans PsJN 0.54 BPHYT_RS16990 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 0.19 BPHYT_RS28995 histidine kinase low > 109
Paraburkholderia bryophila 376MFSha3.1 0.54 H281DRAFT_06288 UDP-N-acetylmuramate: L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase 0.17 H281DRAFT_00885 two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ low > 103
Pseudomonas sp. S08-1 0.54 OH686_09400 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 0.22 OH686_11090 Osmolarity sensory histidine kinase EnvZ low > 80
Dechlorosoma suillum PS 0.54 Dsui_0384 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 0.20 Dsui_2400 signal transduction histidine kinase 0.50 15
Kangiella aquimarina DSM 16071 0.52 B158DRAFT_2035 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase 0.28 B158DRAFT_0685 Signal transduction histidine kinase low > 40
Acinetobacter radioresistens SK82 0.50 MPMX26_03053 UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl- meso-2,6-diaminoheptandioate ligase 0.24 MPMX26_02839 Osmolarity sensor protein EnvZ low > 36
Castellaniella sp019104865 MT123 0.50 ABCV34_RS10690 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 0.17 ABCV34_RS08590 ATP-binding protein low > 48
Magnetospirillum magneticum AMB-1 0.14 AMB_RS00845 UDP-N-acetylmuramate--alanine ligase 0.18 AMB_RS02835 two-component sensor histidine kinase low > 64

Not shown: 15 genomes with orthologs for HGI48_RS18515 only; 3 genomes with orthologs for HGI48_RS19745 only