Conservation of cofitness between HER17_RS04200 and HER17_RS00980 in Pectobacterium carotovorum WPP14

60 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pectobacterium carotovorum WPP14 1.0 HER17_RS04200 7-carboxy-7-deazaguanine synthase QueE 1.0 HER17_RS00980 TonB-dependent vitamin B12 receptor BtuB 0.65 16
Serratia liquefaciens MT49 0.86 IAI46_03675 7-carboxy-7-deazaguanine synthase QueE 0.68 IAI46_24450 TonB-dependent vitamin B12 receptor BtuB low > 86
Dickeya dadantii 3937 0.86 DDA3937_RS16970 7-carboxy-7-deazaguanine synthase QueE 0.53 DDA3937_RS00995 TonB-dependent vitamin B12 receptor BtuB low > 74
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.86 GFF4831 Queuosine Biosynthesis QueE Radical SAM 0.63 GFF2352 Outer membrane vitamin B12 receptor BtuB low > 78
Klebsiella michiganensis M5al 0.85 BWI76_RS22780 7-carboxy-7-deazaguanine synthase QueE 0.52 BWI76_RS00890 vitamin B12/cobalamin outer membrane transporter low > 92
Escherichia coli ECRC100 0.85 OKFHMN_20300 queE 7-carboxy-7-deazaguanine synthase QueE 0.63 OKFHMN_13530 btuB TonB-dependent vitamin B12 receptor BtuB low > 80
Escherichia coli ECRC98 0.85 JDDGAC_23965 queE 7-carboxy-7-deazaguanine synthase QueE 0.63 JDDGAC_17155 btuB TonB-dependent vitamin B12 receptor BtuB low > 86
Escherichia coli ECRC101 0.85 MCAODC_10825 queE 7-carboxy-7-deazaguanine synthase QueE 0.63 MCAODC_04030 btuB TonB-dependent vitamin B12 receptor BtuB low > 87
Escherichia coli ECRC99 0.85 KEDOAH_07830 queE 7-carboxy-7-deazaguanine synthase QueE 0.63 KEDOAH_14630 btuB TonB-dependent vitamin B12 receptor BtuB — —
Escherichia coli BW25113 0.85 b2777 ygcF hypothetical protein (NCBI) 0.63 b3966 btuB vitamin B12/cobalamin outer membrane transporter (NCBI) low > 76
Escherichia coli ECRC62 0.85 BNILDI_10675 queE 7-carboxy-7-deazaguanine synthase QueE 0.63 BNILDI_05850 btuB TonB-dependent vitamin B12 receptor BtuB low > 75
Escherichia coli HS(pFamp)R (ATCC 700891) 0.85 OHPLBJKB_00957 7-carboxy-7-deazaguanine synthase 0.63 OHPLBJKB_04084 Vitamin B12 transporter BtuB low > 73
Escherichia coli ECRC102 0.85 NIAGMN_18070 queE 7-carboxy-7-deazaguanine synthase QueE 0.63 NIAGMN_11280 btuB TonB-dependent vitamin B12 receptor BtuB — —
Escherichia coli ECOR27 0.85 NOLOHH_12170 queE 7-carboxy-7-deazaguanine synthase QueE 0.63 NOLOHH_05675 btuB TonB-dependent vitamin B12 receptor BtuB low > 75
Escherichia fergusonii Becca 0.85 EFB2_01141 7-carboxy-7-deazaguanine synthase 0.53 EFB2_04644 Vitamin B12 transporter BtuB low > 86
Escherichia coli Nissle 1917 0.85 ECOLIN_RS15475 7-carboxy-7-deazaguanine synthase QueE 0.63 ECOLIN_RS22905 TonB-dependent vitamin B12 receptor BtuB low > 55
Escherichia coli ECOR38 0.85 HEPCGN_19205 queE 7-carboxy-7-deazaguanine synthase QueE 0.63 HEPCGN_12185 btuB TonB-dependent vitamin B12 receptor BtuB low > 87
Enterobacter sp. TBS_079 0.84 MPMX20_03645 7-carboxy-7-deazaguanine synthase 0.68 MPMX20_04514 Vitamin B12 transporter BtuB 0.19 48
Enterobacter asburiae PDN3 0.84 EX28DRAFT_2855 putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE 0.65 EX28DRAFT_4429 TonB-dependent vitamin B12 receptor low > 76
Rahnella sp. WP5 0.83 EX31_RS07920 7-carboxy-7-deazaguanine synthase QueE 0.68 EX31_RS14135 TonB-dependent vitamin B12 receptor BtuB low > 89
Pantoea sp. MT58 0.80 IAI47_04140 7-carboxy-7-deazaguanine synthase QueE 0.70 IAI47_00955 TonB-dependent vitamin B12 receptor BtuB low > 76
Dickeya dianthicola 67-19 0.79 HGI48_RS17035 7-carboxy-7-deazaguanine synthase QueE 0.67 HGI48_RS20380 TonB-dependent vitamin B12 receptor BtuB low > 71
Dickeya dianthicola ME23 0.79 DZA65_RS18110 7-carboxy-7-deazaguanine synthase QueE 0.52 DZA65_RS21425 TonB-dependent vitamin B12 receptor BtuB low > 75
Vibrio cholerae E7946 ATCC 55056 0.64 CSW01_06870 7-carboxy-7-deazaguanine synthase QueE 0.29 CSW01_00790 vitamin B12 transporter BtuB low > 62
Alteromonas macleodii MIT1002 0.58 MIT1002_01264 7-carboxy-7-deazaguanine synthase 0.13 MIT1002_00716 Outer membrane cobalamin translocator low > 70
Paraburkholderia sabiae LMG 24235 0.45 QEN71_RS41925 7-carboxy-7-deazaguanine synthase QueE 0.14 QEN71_RS25145 TonB-dependent receptor low > 153
Mucilaginibacter yixingensis YX-36 DSM 26809 0.23 ABZR88_RS09380 7-carboxy-7-deazaguanine synthase QueE 0.11 ABZR88_RS09845 TonB-dependent siderophore receptor low > 71
Pedobacter sp. GW460-11-11-14-LB5 0.23 CA265_RS08930 7-carboxy-7-deazaguanine synthase QueE 0.12 CA265_RS09235 hypothetical protein low > 88
Bacteroides ovatus ATCC 8483 0.22 BACOVA_05261 radical SAM domain protein 0.06 BACOVA_00764 TonB-dependent receptor low > 94
Burkholderia phytofirmans PsJN 0.21 BPHYT_RS01505 7-cyano-7-deazaguanine reductase 0.14 BPHYT_RS04850 TonB-denpendent receptor low > 109
Paraburkholderia graminis OAS925 0.21 ABIE53_000397 7-carboxy-7-deazaguanine synthase 0.14 ABIE53_001246 vitamin B12 transporter low > 113
Paraburkholderia bryophila 376MFSha3.1 0.20 H281DRAFT_02231 7-carboxy-7-deazaguanine synthase, Cx14CxxC type 0.13 H281DRAFT_00136 vitamin B12 transporter low > 103
Rhodospirillum rubrum S1H 0.19 Rru_A1959 Radical SAM (NCBI) 0.11 Rru_A0488 TonB-dependent receptor (NCBI) low > 58
Ralstonia sp. UNC404CL21Col 0.19 ABZR87_RS12145 7-carboxy-7-deazaguanine synthase 0.15 ABZR87_RS00095 TonB-dependent receptor 0.60 15
Azospirillum brasilense Sp245 0.19 AZOBR_RS04155 radical SAM protein 0.09 AZOBR_RS19160 outer membrane cobalamin receptor protein BtuB low > 97
Cupriavidus basilensis FW507-4G11 0.18 RR42_RS11390 7-cyano-7-deazaguanine reductase 0.15 RR42_RS16140 TonB-dependent receptor — —
Caulobacter crescentus NA1000 Δfur 0.18 CCNA_03261 queuosine biosynthesis protein QueE 0.15 CCNA_01826 vitamin B12 receptor low > 67
Caulobacter crescentus NA1000 0.18 CCNA_03261 queuosine biosynthesis protein QueE 0.15 CCNA_01826 vitamin B12 receptor low > 66
Pseudomonas simiae WCS417 0.18 PS417_22405 7-carboxy-7-deazaguanine synthase 0.15 PS417_25210 TonB-dependent receptor low > 88
Pseudomonas fluorescens SBW25-INTG 0.18 PFLU_RS24045 7-carboxy-7-deazaguanine synthase QueE 0.15 PFLU_RS26850 TonB-dependent receptor low > 109
Pseudomonas fluorescens SBW25 0.18 PFLU_RS24045 7-carboxy-7-deazaguanine synthase QueE 0.15 PFLU_RS26850 TonB-dependent receptor low > 109
Ralstonia solanacearum GMI1000 0.17 RS_RS07295 7-carboxy-7-deazaguanine synthase 0.13 RS_RS12050 TonB-dependent receptor low > 80
Ralstonia solanacearum PSI07 0.17 RPSI07_RS16890 7-carboxy-7-deazaguanine synthase 0.13 RPSI07_RS12875 TonB-dependent receptor — —
Pseudomonas sp. RS175 0.17 PFR28_03404 7-carboxy-7-deazaguanine synthase 0.16 PFR28_03938 Vitamin B12 transporter BtuB low > 88
Ralstonia solanacearum IBSBF1503 0.17 RALBFv3_RS00615 7-carboxy-7-deazaguanine synthase 0.14 RALBFv3_RS04495 TonB-dependent receptor — —
Ralstonia solanacearum UW163 0.17 UW163_RS13945 7-carboxy-7-deazaguanine synthase 0.14 UW163_RS09175 TonB-dependent receptor — —
Pseudomonas fluorescens FW300-N2C3 0.17 AO356_18065 7-carboxy-7-deazaguanine synthase 0.15 AO356_14985 TonB-dependent receptor low > 104
Pseudomonas fluorescens FW300-N2E2 0.17 Pf6N2E2_5545 Queuosine Biosynthesis QueE Radical SAM 0.15 Pf6N2E2_4930 Outer membrane vitamin B12 receptor BtuB low > 103
Brevundimonas sp. GW460-12-10-14-LB2 0.17 A4249_RS08695 7-carboxy-7-deazaguanine synthase 0.12 A4249_RS12105 TonB-dependent receptor — —
Pseudomonas fluorescens FW300-N1B4 0.17 Pf1N1B4_629 Queuosine Biosynthesis QueE Radical SAM 0.17 Pf1N1B4_2660 Outer membrane vitamin B12 receptor BtuB low > 87
Pseudomonas fluorescens FW300-N2E3 0.17 AO353_03540 7-carboxy-7-deazaguanine synthase 0.16 AO353_06660 TonB-dependent receptor low > 101
Pseudomonas sp. S08-1 0.17 OH686_19175 7-carboxy-7-deazaguanine synthase 0.18 OH686_15755 Outer membrane vitamin B12 receptor BtuB low > 80
Dyella japonica UNC79MFTsu3.2 0.16 ABZR86_RS10790 7-carboxy-7-deazaguanine synthase QueE 0.20 ABZR86_RS14720 TonB-dependent vitamin B12 receptor low > 74
Rhodanobacter sp. FW510-T8 0.16 OKGIIK_01890 7-carboxy-7-deazaguanine synthase 0.21 OKGIIK_05465 btuB TonB-dependent vitamin B12 receptor low > 52
Acidovorax sp. GW101-3H11 0.16 Ac3H11_3825 Queuosine Biosynthesis QueE Radical SAM 0.17 Ac3H11_985 Outer membrane vitamin B12 receptor BtuB — —
Variovorax sp. OAS795 0.16 ABID97_RS07425 7-carboxy-7-deazaguanine synthase 0.18 ABID97_RS17425 TonB-dependent receptor — —
Pseudomonas putida KT2440 0.16 PP_1225 7-carboxy-7-deazaguanine synthase 0.15 PP_0525 TonB-dependent receptor, B12 family low > 96
Pseudomonas fluorescens GW456-L13 0.16 PfGW456L13_1861 Queuosine Biosynthesis QueE Radical SAM 0.16 PfGW456L13_1324 Outer membrane vitamin B12 receptor BtuB low > 87
Pseudomonas stutzeri RCH2 0.15 Psest_1505 Organic radical activating enzymes 0.18 Psest_3016 TonB-dependent vitamin B12 receptor low > 67
Hydrogenophaga sp. GW460-11-11-14-LB1 0.15 GFF4633 Queuosine Biosynthesis QueE Radical SAM 0.16 GFF3976 Outer membrane vitamin B12 receptor BtuB — —
Marinobacter adhaerens HP15 0.15 HP15_3815 organic radical activating enzyme 0.13 HP15_3953 outer membrane receptor for transport of vitamin B low > 73

Not shown: 23 genomes with orthologs for HER17_RS04200 only; 5 genomes with orthologs for HER17_RS00980 only