Conservation of cofitness between ECD_03708 and ECD_02744 in Escherichia coli BL21

51 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BL21 1.0 ECD_03708 5-methyltetrahydropteroyltriglutamate- homocysteine S-methyltransferase 1.0 ECD_02744 D-3-phosphoglycerate dehydrogenase 0.96 13
Escherichia coli Nissle 1917 1.00 ECOLIN_RS21980 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 1.00 ECOLIN_RS16210 phosphoglycerate dehydrogenase 0.95 14
Escherichia coli BW25113 1.00 b3829 metE 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (NCBI) 1.00 b2913 serA D-3-phosphoglycerate dehydrogenase (NCBI) 0.66 35
Escherichia fergusonii Becca 1.00 EFB2_04808 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 1.00 EFB2_00990 D-3-phosphoglycerate dehydrogenase low > 86
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_04222 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 1.00 OHPLBJKB_00803 D-3-phosphoglycerate dehydrogenase low > 73
Escherichia coli ECOR27 0.99 NOLOHH_06455 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 1.00 NOLOHH_11370 serA phosphoglycerate dehydrogenase 0.87 30
Escherichia coli ECRC62 0.99 BNILDI_05075 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 1.00 BNILDI_09905 serA phosphoglycerate dehydrogenase 0.98 23
Escherichia coli ECOR38 0.99 HEPCGN_13025 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 1.00 HEPCGN_18760 serA phosphoglycerate dehydrogenase 0.97 13
Escherichia coli ECRC100 0.99 OKFHMN_14325 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 1.00 OKFHMN_19460 serA phosphoglycerate dehydrogenase 0.98 27
Escherichia coli ECRC101 0.99 MCAODC_04830 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 1.00 MCAODC_09980 serA phosphoglycerate dehydrogenase 0.76 67
Escherichia coli ECRC98 0.99 JDDGAC_17950 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 1.00 JDDGAC_23100 serA phosphoglycerate dehydrogenase low > 86
Escherichia coli ECRC99 0.99 KEDOAH_13825 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 1.00 KEDOAH_08680 serA phosphoglycerate dehydrogenase — —
Escherichia coli ECRC102 0.99 NIAGMN_12080 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 1.00 NIAGMN_17225 serA phosphoglycerate dehydrogenase — —
Enterobacter asburiae PDN3 0.95 EX28DRAFT_4494 methionine synthase (B12-independent) (EC 2.1.1.14) 0.92 EX28DRAFT_2965 Phosphoglycerate dehydrogenase and related dehydrogenases — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.94 GFF254 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (EC 2.1.1.14) 0.95 GFF3013 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) low > 78
Klebsiella michiganensis M5al 0.94 BWI76_RS01280 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.93 BWI76_RS23920 D-3-phosphoglycerate dehydrogenase low > 92
Enterobacter sp. TBS_079 0.94 MPMX20_04451 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.93 MPMX20_03771 D-3-phosphoglycerate dehydrogenase low > 85
Pectobacterium carotovorum WPP14 0.86 HER17_RS20685 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.85 HER17_RS02725 phosphoglycerate dehydrogenase 0.60 60
Dickeya dadantii 3937 0.85 DDA3937_RS20380 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.83 DDA3937_RS18480 phosphoglycerate dehydrogenase 0.51 37
Dickeya dianthicola ME23 0.85 DZA65_RS00875 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.82 DZA65_RS19540 phosphoglycerate dehydrogenase low > 75
Dickeya dianthicola 67-19 0.85 HGI48_RS00820 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.82 HGI48_RS18400 phosphoglycerate dehydrogenase low > 71
Erwinia tracheiphila SCR3 0.84 LU632_RS24030 metE 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.86 LU632_RS05855 serA phosphoglycerate dehydrogenase low > 74
Serratia liquefaciens MT49 0.84 IAI46_01035 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.85 IAI46_20900 phosphoglycerate dehydrogenase 0.62 49
Rahnella sp. WP5 0.83 EX31_RS14710 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.82 EX31_RS21470 phosphoglycerate dehydrogenase low > 89
Pantoea sp. MT58 0.83 IAI47_18310 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.87 IAI47_03725 phosphoglycerate dehydrogenase low > 76
Pseudomonas fluorescens FW300-N2E2 0.62 Pf6N2E2_5472 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (EC 2.1.1.14) 0.66 Pf6N2E2_3932 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) low > 103
Pseudomonas fluorescens FW300-N1B4 0.62 Pf1N1B4_783 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (EC 2.1.1.14) 0.66 Pf1N1B4_2272 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) low > 87
Pseudomonas sp. RS175 0.61 PFR28_03477 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.66 PFR28_04842 D-3-phosphoglycerate dehydrogenase low > 88
Pseudomonas fluorescens FW300-N2E3 0.61 AO353_16215 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.66 AO353_08510 3-phosphoglycerate dehydrogenase low > 101
Pseudomonas fluorescens FW300-N2C3 0.61 AO356_17740 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.65 AO356_10300 3-phosphoglycerate dehydrogenase low > 104
Pseudomonas stutzeri RCH2 0.60 Psest_1452 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 0.66 Psest_3873 Phosphoglycerate dehydrogenase and related dehydrogenases — —
Vibrio cholerae E7946 ATCC 55056 0.60 CSW01_08575 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.74 CSW01_12555 phosphoglycerate dehydrogenase low > 62
Pseudomonas fluorescens GW456-L13 0.59 PfGW456L13_3767 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (EC 2.1.1.14) 0.66 PfGW456L13_943 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) low > 87
Pseudomonas fluorescens SBW25-INTG 0.59 PFLU_RS17405 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.65 PFLU_RS28695 phosphoglycerate dehydrogenase low > 109
Pseudomonas fluorescens SBW25 0.59 PFLU_RS17405 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.65 PFLU_RS28695 phosphoglycerate dehydrogenase low > 109
Castellaniella sp019104865 MT123 0.59 ABCV34_RS04445 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.53 ABCV34_RS15150 phosphoglycerate dehydrogenase — —
Pseudomonas sp. S08-1 0.59 OH686_20470 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.67 OH686_11280 D-3-phosphoglycerate dehydrogenase low > 80
Azospirillum brasilense Sp245 0.56 AZOBR_RS24275 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 0.55 AZOBR_RS10940 3-phosphoglycerate dehydrogenase — —
Acidovorax sp. GW101-3H11 0.55 Ac3H11_2345 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (EC 2.1.1.14) 0.65 Ac3H11_4790 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) low > 79
Shewanella sp. ANA-3 0.55 Shewana3_3469 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase (RefSeq) 0.70 Shewana3_3416 D-3-phosphoglycerate dehydrogenase (RefSeq) low > 73
Variovorax sp. SCN45 0.55 GFF795 5-methyltetrahydropteroyltriglutamate--homocystei ne methyltransferase (EC 2.1.1.14) 0.63 GFF2538 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) low > 127
Shewanella loihica PV-4 0.55 Shew_2986 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (RefSeq) 0.70 Shew_3196 D-3-phosphoglycerate dehydrogenase (RefSeq) low > 60
Shewanella oneidensis MR-1 0.55 SO0818 metE 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (NCBI ptt file) 0.70 SO0862 serA D-3-phosphoglycerate dehydrogenase (NCBI ptt file) 0.86 62
Marinobacter adhaerens HP15 0.54 HP15_457 5-methyltetrahydropteroyltriglutamate- homocysteine S-methyltransferase 0.65 HP15_2554 D-3-phosphoglycerate dehydrogenase-like protein — —
Cupriavidus basilensis FW507-4G11 0.53 RR42_RS30660 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.48 RR42_RS27010 D-3-phosphoglycerate dehydrogenase low > 128
Shewanella amazonensis SB2B 0.53 Sama_2627 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase (RefSeq) 0.69 Sama_2949 D-3-phosphoglycerate dehydrogenase (RefSeq) 0.88 62
Variovorax sp. OAS795 0.52 ABID97_RS19395 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.63 ABID97_RS07235 phosphoglycerate dehydrogenase low > 91
Dyella japonica UNC79MFTsu3.2 0.50 ABZR86_RS03225 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.64 ABZR86_RS09635 phosphoglycerate dehydrogenase low > 74
Rhodanobacter denitrificans MT42 0.49 LRK55_RS11870 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.62 LRK55_RS02935 phosphoglycerate dehydrogenase low > 63
Rhodanobacter denitrificans FW104-10B01 0.49 LRK54_RS12135 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.62 LRK54_RS03185 phosphoglycerate dehydrogenase low > 59
Rhodospirillum rubrum S1H 0.48 Rru_A1718 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase (NCBI) 0.58 Rru_A2456 Phosphoglycerate dehydrogenase (NCBI) — —
Bifidobacterium breve UCC2003 0.42 BBR_RS15405 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.45 BBR_RS16970 phosphoglycerate dehydrogenase low > 34

Not shown: 16 genomes with orthologs for ECD_03708 only; 14 genomes with orthologs for ECD_02744 only