Conservation of cofitness between CSW01_01465 and CSW01_13635 in Vibrio cholerae E7946 ATCC 55056

71 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_01465 ketohydroxyglutarate aldolase 1.0 CSW01_13635 thiol:disulfide interchange protein DsbD 0.69 6
Pantoea sp. MT58 0.44 IAI47_08500 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.43 IAI47_17335 protein-disulfide reductase DsbD low > 76
Pantoea agglomerans CFBP13505 P0401 0.44 PagCFBP13505_RS02380 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.44 PagCFBP13505_RS09505 protein-disulfide reductase DsbD low > 74
Serratia liquefaciens MT49 0.44 IAI46_23180 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.45 IAI46_01465 protein-disulfide reductase DsbD low > 87
Enterobacter asburiae PDN3 0.44 EX28DRAFT_0706 Entner-Doudoroff aldolase 0.46 EX28DRAFT_3333 Thiol:disulfide interchange protein low > 76
Enterobacter sp. TBS_079 0.44 MPMX20_02755 KHG/KDPG aldolase 0.45 MPMX20_00416 Thiol:disulfide interchange protein DsbD low > 85
Shewanella oneidensis MR-1 0.44 SO2486 eda 2-deydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase (NCBI ptt file) 0.44 SO0696 dsbD thiol:disulfide interchange protein DsbD (NCBI ptt file) — —
Dickeya dadantii 3937 0.43 DDA3937_RS10140 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.43 DDA3937_RS02705 protein-disulfide reductase DsbD low > 74
Rahnella sp. WP5 0.43 EX31_RS10625 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.46 EX31_RS08975 protein-disulfide reductase DsbD low > 89
Dickeya dianthicola 67-19 0.43 HGI48_RS10170 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.42 HGI48_RS02680 protein-disulfide reductase DsbD low > 71
Dickeya dianthicola ME23 0.43 DZA65_RS10585 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.42 DZA65_RS02835 protein-disulfide reductase DsbD low > 75
Pectobacterium carotovorum WPP14 0.43 HER17_RS11775 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.47 HER17_RS18850 protein-disulfide reductase DsbD low > 75
Shewanella loihica PV-4 0.43 Shew_2045 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (RefSeq) 0.42 Shew_3266 dipZ thiol:disulfide interchange protein precursor (RefSeq) — —
Shewanella sp. ANA-3 0.43 Shewana3_2148 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (RefSeq) 0.43 Shewana3_3576 dipZ thiol:disulfide interchange protein precursor (RefSeq) — —
Shewanella amazonensis SB2B 0.42 Sama_1809 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (RefSeq) 0.42 Sama_0538 dipZ thiol:disulfide interchange protein precursor (RefSeq) — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.42 GFF1629 4-hydroxy-2-oxoglutarate aldolase (EC 4.1.3.16) @ 2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14) 0.46 GFF2016 Cytochrome c-type biogenesis protein DsbD, protein-disulfide reductase (EC 1.8.1.8) low > 78
Alteromonas macleodii MIT1002 0.42 MIT1002_02403 KHG/KDPG aldolase 0.38 MIT1002_03939 Thiol:disulfide interchange protein DsbD precursor — —
Marinobacter adhaerens HP15 0.40 HP15_2177 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 0.30 HP15_2101 membrane protein containing cytochrome c assembly protein, transmembrane region domain low > 73
Escherichia coli Nissle 1917 0.40 ECOLIN_RS10305 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.47 ECOLIN_RS24030 protein-disulfide reductase DsbD — —
Escherichia coli ECRC98 0.40 JDDGAC_00920 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.47 JDDGAC_16085 dsbD protein-disulfide reductase DsbD low > 87
Escherichia coli BW25113 0.40 b1850 eda keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (NCBI) 0.47 b4136 dipZ thiol:disulfide interchange protein precursor (NCBI) low > 76
Escherichia coli ECRC100 0.40 OKFHMN_26345 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.47 OKFHMN_12450 dsbD protein-disulfide reductase DsbD low > 79
Escherichia coli ECRC102 0.40 NIAGMN_01715 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.47 NIAGMN_10295 dsbD protein-disulfide reductase DsbD — —
Escherichia coli ECOR38 0.40 HEPCGN_04750 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.46 HEPCGN_10675 dsbD protein-disulfide reductase DsbD low > 88
Escherichia coli BL21 0.40 ECD_01821 KHG/KDPG aldolase; 2-dehydro-3-deoxy-phosphogluconate/4-hydroxy-2- oxoglutarate aldolase 0.47 ECD_04006 thiol:disulfide interchange protein and activator of DsbC — —
Escherichia coli ECRC62 0.40 BNILDI_15650 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.47 BNILDI_06775 dsbD protein-disulfide reductase DsbD low > 75
Escherichia coli ECRC101 0.40 MCAODC_19060 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.46 MCAODC_02960 dsbD protein-disulfide reductase DsbD low > 87
Escherichia fergusonii Becca 0.40 EFB2_02093 KHG/KDPG aldolase 0.47 EFB2_04399 Thiol:disulfide interchange protein DsbD low > 86
Escherichia coli ECRC99 0.40 KEDOAH_01760 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.47 KEDOAH_15715 dsbD protein-disulfide reductase DsbD — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.40 OHPLBJKB_01879 KHG/KDPG aldolase 0.47 OHPLBJKB_03907 Thiol:disulfide interchange protein DsbD low > 74
Escherichia coli ECOR27 0.39 NOLOHH_16855 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.47 NOLOHH_04715 dsbD protein-disulfide reductase DsbD low > 76
Herbaspirillum seropedicae SmR1 0.39 HSERO_RS05525 ketohydroxyglutarate aldolase 0.29 HSERO_RS00715 thiol:disulfide interchange protein — —
Pseudomonas stutzeri RCH2 0.39 Psest_0854 Entner-Doudoroff aldolase 0.27 Psest_1603 Thiol:disulfide interchange protein — —
Erwinia tracheiphila HP pepo 2.2 0.39 IJEDHG_22200 eda keto-deoxy-phosphogluconate aldolase 0.40 IJEDHG_07065 Thiol:disulfide interchange protein DsbD low > 61
Erwinia tracheiphila SCR3 0.39 LU632_RS13355 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.40 LU632_RS01840 protein-disulfide reductase DsbD low > 73
Klebsiella pneumoniae MKP103 0.38 KDGMDA_25360 keto-deoxy-phosphogluconate aldolase 0.45 KDGMDA_10805 Thiol:disulfide interchange protein DsbD low > 95
Klebsiella michiganensis M5al 0.38 BWI76_RS18095 ketohydroxyglutarate aldolase 0.47 BWI76_RS02315 protein-disulfide reductase DsbD — —
Pseudomonas aeruginosa MRSN321 0.38 DY961_RS01030 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.24 DY961_RS05265 protein-disulfide reductase DsbD — —
Pseudomonas aeruginosa PA14 0.38 IKLFDK_16165 keto-deoxy-phosphogluconate aldolase 0.24 IKLFDK_12170 Thiol:disulfide interchange protein DsbD 2 — —
Pseudomonas aeruginosa PUPa3 0.37 DQ20_RS34505 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.24 DQ20_RS55390 protein-disulfide reductase DsbD low > 101
Pseudomonas fluorescens FW300-N2C3 0.37 AO356_05150 keto-deoxy-phosphogluconate aldolase 0.28 AO356_02870 thiol:disulfide interchange protein — —
Ralstonia solanacearum PSI07 0.37 RPSI07_RS05475 ketohydroxyglutarate aldolase 0.28 RPSI07_RS10195 protein-disulfide reductase DsbD — —
Pseudomonas sp. RS175 0.36 PFR28_00575 2-dehydro-3-deoxy-phosphogluconate aldolase 0.27 PFR28_01029 Thiol:disulfide interchange protein DsbD — —
Pseudomonas fluorescens FW300-N2E2 0.36 Pf6N2E2_2883 4-Hydroxy-2-oxoglutarate aldolase (EC 4.1.3.16) @ 2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14) 0.28 Pf6N2E2_2398 Cytochrome c-type biogenesis protein DsbD, protein-disulfide reductase (EC 1.8.1.8) — —
Pseudomonas fluorescens FW300-N1B4 0.36 Pf1N1B4_587 4-hydroxy-2-oxoglutarate aldolase (EC 4.1.3.16) @ 2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14) 0.27 Pf1N1B4_210 Cytochrome c-type biogenesis protein DsbD, protein-disulfide reductase (EC 1.8.1.8) — —
Pseudomonas lactucae CFBP13502 0.36 GEMAOFIL_04556 2-dehydro-3-deoxy-phosphogluconate aldolase 0.25 GEMAOFIL_04105 Thiol:disulfide interchange protein DsbD — —
Cupriavidus basilensis FW507-4G11 0.36 RR42_RS28865 2-dehydro-3-deoxyphosphogluconate aldolase 0.29 RR42_RS19110 thiol:disulfide interchange protein — —
Pseudomonas sp. SVBP6 0.36 COO64_RS04600 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.24 COO64_RS18765 dsbD protein-disulfide reductase DsbD low > 93
Pseudomonas sp. DMC3 0.36 GFF5138 2-dehydro-3-deoxy-phosphogluconate aldolase 0.29 GFF4549 Thiol:disulfide interchange protein DsbD — —
Pseudomonas simiae WCS417 0.35 PS417_22100 keto-deoxy-phosphogluconate aldolase 0.26 PS417_19525 thiol:disulfide interchange protein — —
Pseudomonas orientalis W4I3 0.35 QF045_RS24235 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.26 QF045_RS21665 protein-disulfide reductase DsbD — —
Pseudomonas fluorescens GW456-L13 0.35 PfGW456L13_1903 4-hydroxy-2-oxoglutarate aldolase (EC 4.1.3.16) @ 2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14) 0.28 PfGW456L13_2298 Cytochrome c-type biogenesis protein DsbD, protein-disulfide reductase (EC 1.8.1.8) — —
Pseudomonas syringae pv. syringae B728a 0.35 Psyr_1122 2-keto-3-deoxy-phosphogluconate aldolase 0.24 Psyr_4398 Protein-disulfide reductase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.35 Psyr_1122 2-keto-3-deoxy-phosphogluconate aldolase 0.24 Psyr_4398 Protein-disulfide reductase — —
Pseudomonas fluorescens SBW25-INTG 0.35 PFLU_RS23715 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.25 PFLU_RS21490 protein-disulfide reductase DsbD — —
Pseudomonas fluorescens SBW25 0.35 PFLU_RS23715 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.25 PFLU_RS21490 protein-disulfide reductase DsbD — —
Ralstonia solanacearum UW163 0.35 UW163_RS20970 ketohydroxyglutarate aldolase 0.27 UW163_RS06570 protein-disulfide reductase DsbD — —
Ralstonia solanacearum IBSBF1503 0.35 RALBFv3_RS18160 ketohydroxyglutarate aldolase 0.27 RALBFv3_RS07045 protein-disulfide reductase DsbD — —
Pseudomonas putida KT2440 0.35 PP_1024 KHG/KDPG aldolase 0.25 PP_0561 thiol/disulfide interchange protein 1 — —
Ralstonia sp. UNC404CL21Col 0.35 ABZR87_RS19090 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.28 ABZR87_RS02695 protein-disulfide reductase DsbD — —
Pseudomonas sp. BP01 0.35 JOY50_RS11460 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.26 JOY50_RS23140 protein-disulfide reductase DsbD low > 84
Pseudomonas fluorescens FW300-N2E3 0.35 AO353_03350 keto-deoxy-phosphogluconate aldolase 0.25 AO353_19365 thiol:disulfide interchange protein — —
Ralstonia solanacearum GMI1000 0.34 RS_RS22875 ketohydroxyglutarate aldolase 0.27 RS_RS14985 thiol:disulfide interchange protein DsbD — —
Pseudomonas segetis P6 0.34 MPMX49_02829 2-dehydro-3-deoxy-phosphogluconate aldolase 0.26 MPMX49_04100 Thiol:disulfide interchange protein DsbD — —
Castellaniella sp019104865 MT123 0.34 ABCV34_RS08610 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.27 ABCV34_RS03205 protein-disulfide reductase DsbD low > 48
Paraburkholderia sabiae LMG 24235 0.33 QEN71_RS26915 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.23 QEN71_RS28120 protein-disulfide reductase DsbD — —
Burkholderia phytofirmans PsJN 0.33 BPHYT_RS16730 2-dehydro-3-deoxyphosphogluconate aldolase 0.23 BPHYT_RS17970 thiol:disulfide interchange protein — —
Paraburkholderia graminis OAS925 0.33 ABIE53_003516 2-dehydro-3-deoxyphosphogluconate aldolase/(4S)-4-hydroxy-2-oxoglutarate aldolase 0.26 ABIE53_000167 thiol:disulfide interchange protein DsbD — —
Paraburkholderia bryophila 376MFSha3.1 0.32 H281DRAFT_04277 2-keto-3-deoxy-phosphogluconate aldolase 0.23 H281DRAFT_05598 thiol:disulfide interchange protein DsbD — —
Methylophilus sp. DMC18 0.32 GFF286 KHG/KDPG aldolase 0.29 GFF2039 Thiol:disulfide interchange protein DsbD — —
Acinetobacter baumannii LAC-4 0.30 RR41_RS16525 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.24 RR41_RS00770 protein-disulfide reductase DsbD low > 55
Brevundimonas sp. GW460-12-10-14-LB2 0.23 A4249_RS10775 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.17 A4249_RS11500 protein-disulfide reductase DsbD — —

Not shown: 36 genomes with orthologs for CSW01_01465 only; 5 genomes with orthologs for CSW01_13635 only