Conservation of cofitness between CSW01_08400 and CSW01_11560 in Vibrio cholerae E7946 ATCC 55056

60 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_08400 cystathionine beta-lyase 1.0 CSW01_11560 riboflavin biosynthesis protein RibD 0.66 20
Shewanella loihica PV-4 0.66 Shew_1789 cystathionine beta-lyase (RefSeq) 0.52 Shew_1187 riboflavin biosynthesis protein RibD (RefSeq) — —
Shewanella oneidensis MR-1 0.65 SO2191 metC cystathionine beta-lyase (NCBI ptt file) 0.50 SO3469 ribD riboflavin biosynthesis protein RibD (NCBI ptt file) — —
Shewanella sp. ANA-3 0.65 Shewana3_2414 cystathionine beta-lyase (RefSeq) 0.50 Shewana3_1096 5-amino-6-(5-phosphoribosylamino)uracil reductase / diaminohydroxyphosphoribosylaminopyrimidine deaminase (RefSeq) — —
Pectobacterium carotovorum WPP14 0.64 HER17_RS19690 cystathionine beta-lyase 0.55 HER17_RS15960 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD — —
Shewanella amazonensis SB2B 0.64 Sama_2008 cystathionine beta-lyase (RefSeq) 0.48 Sama_1016 diaminohydroxyphosphoribosylaminopyrimidine deaminase., 5-amino-6-(5-phosphoribosylamino)uracil reductase (RefSeq) — —
Dickeya dadantii 3937 0.63 DDA3937_RS01815 cystathionine beta-lyase 0.50 DDA3937_RS05505 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD — —
Dickeya dianthicola ME23 0.63 DZA65_RS01785 cystathionine beta-lyase 0.50 DZA65_RS05890 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD — —
Dickeya dianthicola 67-19 0.62 HGI48_RS01710 cystathionine beta-lyase 0.50 HGI48_RS05565 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD — —
Serratia liquefaciens MT49 0.62 IAI46_21725 cystathionine beta-lyase 0.53 IAI46_04895 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD — —
Rahnella sp. WP5 0.61 EX31_RS08025 cystathionine beta-lyase 0.53 EX31_RS22125 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD — —
Escherichia coli Nissle 1917 0.60 ECOLIN_RS17315 cystathionine beta-lyase 0.51 ECOLIN_RS02505 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.60 GFF3120 Cystathionine beta-lyase (EC 4.4.1.8) 0.48 GFF4318 Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193) — —
Escherichia coli BW25113 0.60 b3008 metC cystathionine beta-lyase (NCBI) 0.53 b0414 ribD fused diaminohydroxyphosphoribosylaminopyrimidine deaminase and 5-amino-6-(5-phosphoribosylamino) uracil reductase (NCBI) — —
Enterobacter asburiae PDN3 0.60 EX28DRAFT_3046 cystathionine beta-lyase, bacterial 0.53 EX28DRAFT_2556 diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) — —
Escherichia coli ECRC62 0.60 BNILDI_00780 metC cystathionine beta-lyase 0.53 BNILDI_22815 ribD bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.60 OHPLBJKB_00693 Cystathionine beta-lyase MetC 0.53 OHPLBJKB_03262 Riboflavin biosynthesis protein RibD — —
Escherichia coli ECOR27 0.60 NOLOHH_10735 metC cystathionine beta-lyase 0.53 NOLOHH_01400 ribD bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD — —
Escherichia fergusonii Becca 0.60 EFB2_00802 Cystathionine beta-lyase MetC 0.51 EFB2_03643 Riboflavin biosynthesis protein RibD — —
Escherichia coli ECRC99 0.60 KEDOAH_09185 metC cystathionine beta-lyase 0.51 KEDOAH_19510 ribD bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD — —
Escherichia coli ECRC98 0.60 JDDGAC_22595 metC cystathionine beta-lyase 0.51 JDDGAC_12110 ribD bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD — —
Escherichia coli ECRC100 0.60 OKFHMN_18960 metC cystathionine beta-lyase 0.51 OKFHMN_08455 ribD bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD — —
Escherichia coli ECRC101 0.60 MCAODC_09475 metC cystathionine beta-lyase 0.51 MCAODC_27680 ribD bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD — —
Escherichia coli ECRC102 0.60 NIAGMN_16725 metC cystathionine beta-lyase 0.51 NIAGMN_06510 ribD bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD — —
Escherichia coli ECOR38 0.60 HEPCGN_17825 metC cystathionine beta-lyase 0.52 HEPCGN_07080 ribD bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD — —
Escherichia coli BL21 0.60 ECD_02881 cystathionine beta-lyase, PLP-dependent 0.53 ECD_00362 fused diaminohydroxyphosphoribosylaminopyrimidine deaminase and 5-amino-6-(5-phosphoribosylamino) uracil reductase — —
Enterobacter sp. TBS_079 0.60 MPMX20_03852 Cystathionine beta-lyase MetC 0.51 MPMX20_01006 Riboflavin biosynthesis protein RibD — —
Klebsiella michiganensis M5al 0.60 BWI76_RS24285 cystathionine beta-lyase 0.52 BWI76_RS06350 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase — —
Klebsiella pneumoniae MRSN742743 0.59 GJGHJB_00690 metC cystathionine beta-lyase 0.53 GJGHJB_03904 ribD bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD — —
Klebsiella pneumoniae MKP103 0.59 KDGMDA_05120 cystathionine beta-lyase 0.53 KDGMDA_14440 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD — —
Erwinia tracheiphila HP pepo 2.2 0.58 IJEDHG_14525 metC cystathionine beta-lyase 0.51 IJEDHG_25995 ribD bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD — —
Pantoea agglomerans CFBP13505 P0401 0.57 PagCFBP13516_RS03455 metC cystathionine beta-lyase 0.54 PagCFBP13516_RS15020 ribD bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD — —
Pantoea sp. MT58 0.57 IAI47_03215 cystathionine beta-lyase 0.53 IAI47_14770 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD — —
Erwinia tracheiphila SCR3 0.57 LU632_RS20545 metC cystathionine beta-lyase 0.51 LU632_RS18595 ribD bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD — —
Erwinia amylovora T8 0.56 OLJFJH_07820 cystathionine beta-lyase 0.54 OLJFJH_18090 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD — —
Sphingobium sp. HT1-2 0.50 GFF585 Cystathionine beta-lyase (EC 4.4.1.8) 0.28 GFF3255 Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193) — —
Sphingomonas koreensis DSMZ 15582 0.49 Ga0059261_1388 cystathionine beta-lyase, bacterial 0.26 Ga0059261_2336 diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) — —
Magnetospirillum magneticum AMB-1 0.48 AMB_RS06585 cystathionine beta-lyase 0.31 AMB_RS11825 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD — —
Pseudomonas fluorescens FW300-N2E3 0.47 AO353_24330 cystathionine beta-lyase 0.48 AO353_06715 diaminohydroxyphosphoribosylaminopyrimidine deaminase — —
Rhodopseudomonas palustris CGA009 0.45 TX73_013235 cystathionine beta-lyase 0.31 TX73_014125 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD — —
Pseudomonas sp. SVBP6 0.45 COO64_RS09240 metC cystathionine beta-lyase 0.47 COO64_RS15890 ribD bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD — —
Azospirillum brasilense Sp245 0.44 AZOBR_RS08650 cystathionine beta-lyase 0.28 AZOBR_RS10025 5-amino-6-(5-phosphoribosylamino)uracil reductase — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.43 GFF5026 Cystathionine beta-lyase (EC 4.4.1.8) 0.31 GFF5160 Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193) — —
Rhodospirillum rubrum S1H 0.42 Rru_A1613 Cystathionine beta-lyase (NCBI) 0.27 Rru_A1825 bifunctional deaminase-reductase (NCBI) — —
Azospirillum sp. SherDot2 0.41 MPMX19_01339 Cystathionine beta-lyase MetC 0.31 MPMX19_00736 Riboflavin biosynthesis protein RibD — —
Variovorax sp. OAS795 0.39 ABID97_RS22430 cystathionine beta-lyase 0.38 ABID97_RS17935 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD — —
Ralstonia sp. UNC404CL21Col 0.39 ABZR87_RS11250 cystathionine beta-lyase 0.43 ABZR87_RS08885 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD — —
Ralstonia solanacearum PSI07 0.39 RPSI07_RS02185 cystathionine beta-lyase 0.42 RPSI07_RS20395 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD — —
Paraburkholderia sabiae LMG 24235 0.39 QEN71_RS22165 cystathionine beta-lyase 0.42 QEN71_RS03300 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD — —
Ralstonia solanacearum UW163 0.38 UW163_RS18620 cystathionine beta-lyase 0.42 UW163_RS00740 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD — —
Ralstonia solanacearum IBSBF1503 0.38 RALBFv3_RS20555 cystathionine beta-lyase 0.42 RALBFv3_RS12825 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD — —
Variovorax sp. SCN45 0.37 GFF1749 Cystathionine beta-lyase (EC 4.4.1.8) 0.35 GFF568 Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193) — —
Burkholderia phytofirmans PsJN 0.37 BPHYT_RS09190 cystathionine beta-lyase 0.40 BPHYT_RS15380 diaminohydroxyphosphoribosylaminopyrimidine deaminase — —
Paraburkholderia bryophila 376MFSha3.1 0.37 H281DRAFT_00859 cystathionine beta-lyase 0.40 H281DRAFT_04019 diaminohydroxyphosphoribosylaminopyrimidine deaminase — —
Pseudomonas syringae pv. syringae B728a 0.37 Psyr_0607 cystathionine beta-lyase 0.46 Psyr_4462 diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.37 Psyr_0607 cystathionine beta-lyase 0.46 Psyr_4462 diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase — —
Cupriavidus basilensis FW507-4G11 0.37 RR42_RS30610 cystathionine beta-lyase 0.41 RR42_RS15555 diaminohydroxyphosphoribosylaminopyrimidine deaminase — —
Castellaniella sp019104865 MT123 0.35 ABCV34_RS12385 PLP-dependent aspartate aminotransferase family protein 0.30 ABCV34_RS10545 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD — —
Herbaspirillum seropedicae SmR1 0.35 HSERO_RS14995 cystathionine beta-lyase 0.39 HSERO_RS18235 diaminohydroxyphosphoribosylaminopyrimidine deaminase — —
Ralstonia solanacearum GMI1000 0.34 RS_RS08260 cystathionine beta-lyase 0.42 RS_RS03600 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD — —
Acidovorax sp. GW101-3H11 0.27 Ac3H11_4146 Cystathionine beta-lyase (EC 4.4.1.8) 0.30 Ac3H11_1461 Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193) — —

Not shown: 8 genomes with orthologs for CSW01_08400 only; 48 genomes with orthologs for CSW01_11560 only