Conservation of cofitness between CSW01_05775 and CSW01_10080 in Vibrio cholerae E7946 ATCC 55056

74 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_05775 imidazole glycerol phosphate synthase cyclase subunit 1.0 CSW01_10080 4-amino-4-deoxychorismate lyase 0.69 8
Enterobacter sp. TBS_079 0.88 MPMX20_03007 Imidazole glycerol phosphate synthase subunit HisF 0.28 MPMX20_01776 Aminodeoxychorismate lyase low > 85
Enterobacter asburiae PDN3 0.88 EX28DRAFT_0534 imidazoleglycerol phosphate synthase, cyclase subunit 0.33 EX28DRAFT_1833 aminodeoxychorismate lyase low > 76
Escherichia coli ECRC101 0.87 MCAODC_20450 hisF Imidazole glycerol phosphate synthase subunit HisF 0.33 MCAODC_22920 pabC aminodeoxychorismate lyase low > 87
Escherichia coli ECRC100 0.87 OKFHMN_24490 hisF Imidazole glycerol phosphate synthase subunit HisF 0.33 OKFHMN_03560 pabC aminodeoxychorismate lyase — —
Escherichia coli ECRC102 0.87 NIAGMN_22435 hisF Imidazole glycerol phosphate synthase subunit HisF 0.33 NIAGMN_24270 pabC aminodeoxychorismate lyase — —
Escherichia coli ECRC62 0.87 BNILDI_14715 hisF Imidazole glycerol phosphate synthase subunit HisF 0.33 BNILDI_19250 pabC aminodeoxychorismate lyase low > 75
Escherichia fergusonii Becca 0.87 EFB2_01831 Imidazole glycerol phosphate synthase subunit HisF 0.33 EFB2_02879 Aminodeoxychorismate lyase low > 86
Escherichia coli ECRC99 0.87 KEDOAH_03660 hisF Imidazole glycerol phosphate synthase subunit HisF 0.33 KEDOAH_24195 pabC aminodeoxychorismate lyase — —
Escherichia coli ECRC98 0.87 JDDGAC_28600 hisF Imidazole glycerol phosphate synthase subunit HisF 0.33 JDDGAC_07220 pabC aminodeoxychorismate lyase low > 87
Escherichia coli BW25113 0.87 b2025 hisF imidazole glycerol phosphate synthase subunit HisF (NCBI) 0.33 b1096 pabC 4-amino-4-deoxychorismate lyase (NCBI) low > 76
Escherichia coli ECOR38 0.87 HEPCGN_03195 hisF Imidazole glycerol phosphate synthase subunit HisF 0.32 HEPCGN_23920 pabC aminodeoxychorismate lyase low > 88
Escherichia coli ECOR27 0.87 NOLOHH_15805 hisF Imidazole glycerol phosphate synthase subunit HisF 0.33 NOLOHH_21090 pabC aminodeoxychorismate lyase low > 76
Klebsiella michiganensis M5al 0.87 BWI76_RS18950 imidazole glycerol phosphate synthase cyclase subunit 0.32 BWI76_RS11105 aminodeoxychorismate lyase low > 92
Escherichia coli Nissle 1917 0.87 ECOLIN_RS11970 imidazole glycerol phosphate synthase subunit HisF 0.33 ECOLIN_RS06330 aminodeoxychorismate lyase low > 55
Klebsiella pneumoniae MKP103 0.87 KDGMDA_26120 Imidazole glycerol phosphate synthase subunit HisF 0.31 KDGMDA_18710 aminodeoxychorismate lyase low > 95
Escherichia coli HS(pFamp)R (ATCC 700891) 0.87 OHPLBJKB_01675 Imidazole glycerol phosphate synthase subunit HisF 0.33 OHPLBJKB_02570 Aminodeoxychorismate lyase low > 74
Escherichia coli BL21 0.87 ECD_01927 imidazole glycerol phosphate synthase, catalytic subunit with HisH 0.33 ECD_01092 4-amino-4-deoxychorismate lyase component of para-aminobenzoate synthase multienzyme complex — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.86 GFF3907 Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) 0.29 GFF3378 Aminodeoxychorismate lyase (EC 4.1.3.38) low > 78
Pectobacterium carotovorum WPP14 0.85 HER17_RS12255 imidazole glycerol phosphate synthase subunit HisF 0.33 HER17_RS08665 aminodeoxychorismate lyase low > 75
Serratia liquefaciens MT49 0.85 IAI46_08185 imidazole glycerol phosphate synthase subunit HisF 0.33 IAI46_09805 aminodeoxychorismate lyase low > 87
Dickeya dadantii 3937 0.85 DDA3937_RS09710 imidazole glycerol phosphate synthase subunit HisF 0.32 DDA3937_RS23255 aminodeoxychorismate lyase low > 74
Pantoea sp. MT58 0.85 IAI47_07065 imidazole glycerol phosphate synthase subunit HisF 0.30 IAI47_12055 aminodeoxychorismate lyase low > 76
Rahnella sp. WP5 0.85 EX31_RS11465 imidazole glycerol phosphate synthase subunit HisF 0.30 EX31_RS24450 aminodeoxychorismate lyase low > 89
Pantoea agglomerans CFBP13505 P0401 0.85 PagCFBP13505_RS01185 imidazole glycerol phosphate synthase subunit HisF 0.28 PagCFBP13505_RS05280 aminodeoxychorismate lyase low > 74
Dickeya dianthicola ME23 0.84 DZA65_RS10030 imidazole glycerol phosphate synthase subunit HisF 0.32 DZA65_RS13640 aminodeoxychorismate lyase 0.65 59
Dickeya dianthicola 67-19 0.84 HGI48_RS09720 imidazole glycerol phosphate synthase subunit HisF 0.33 HGI48_RS13170 aminodeoxychorismate lyase — —
Erwinia tracheiphila SCR3 0.84 LU632_RS08920 hisF imidazole glycerol phosphate synthase subunit HisF 0.33 LU632_RS14805 pabC aminodeoxychorismate lyase low > 73
Erwinia tracheiphila HP pepo 2.2 0.84 IJEDHG_19065 hisF imidazole glycerol phosphate synthase subunit HisF 0.33 IJEDHG_00665 pabC aminodeoxychorismate lyase low > 61
Erwinia amylovora T8 0.84 OLJFJH_12155 imidazole glycerol phosphate synthase subunit HisF 0.32 OLJFJH_15515 aminodeoxychorismate lyase 0.79 58
Alteromonas macleodii MIT1002 0.76 MIT1002_02638 Imidazole glycerol phosphate synthase subunit HisF 0.29 MIT1002_01736 Aminodeoxychorismate lyase low > 70
Shewanella oneidensis MR-1 0.74 SO2068 hisF hisF protein (cyclase) (NCBI ptt file) 0.29 SO2615 pabC 4-amino-4-deoxychorismate lyase (NCBI ptt file) low > 76
Shewanella sp. ANA-3 0.74 Shewana3_1848 imidazole glycerol phosphate synthase subunit HisF (RefSeq) 0.28 Shewana3_1764 aminodeoxychorismate lyase apoprotein (RefSeq) — —
Shewanella loihica PV-4 0.74 Shew_2203 imidazole glycerol phosphate synthase subunit HisF (RefSeq) 0.26 Shew_1577 aminotransferase, class IV (RefSeq) low > 60
Lysobacter sp. OAE881 0.66 ABIE51_RS13300 imidazole glycerol phosphate synthase subunit HisF 0.25 ABIE51_RS13925 aminodeoxychorismate lyase low > 62
Dyella japonica UNC79MFTsu3.2 0.65 ABZR86_RS06705 imidazole glycerol phosphate synthase subunit HisF 0.24 ABZR86_RS06150 aminodeoxychorismate lyase low > 74
Rhodanobacter denitrificans FW104-10B01 0.65 LRK54_RS01580 imidazole glycerol phosphate synthase subunit HisF 0.26 LRK54_RS01165 aminodeoxychorismate lyase low > 59
Rhodanobacter sp000427505 FW510-R12 0.65 LRK53_RS08485 imidazole glycerol phosphate synthase subunit HisF 0.28 LRK53_RS08905 aminodeoxychorismate lyase low > 59
Rhodanobacter denitrificans MT42 0.64 LRK55_RS01360 imidazole glycerol phosphate synthase subunit HisF 0.26 LRK55_RS00940 aminodeoxychorismate lyase low > 63
Rhodanobacter sp. FW510-T8 0.64 OKGIIK_04975 hisF imidazole glycerol phosphate synthase subunit HisF 0.25 OKGIIK_05735 pabC aminodeoxychorismate lyase low > 53
Pseudomonas sp. S08-1 0.43 OH686_14595 Imidazole glycerol phosphate synthase cyclase subunit 0.28 OH686_22155 aminodeoxychorismate lyase low > 80
Mucilaginibacter yixingensis YX-36 DSM 26809 0.43 ABZR88_RS06855 imidazole glycerol phosphate synthase subunit HisF 0.13 ABZR88_RS03990 aminotransferase class IV low > 71
Pseudomonas aeruginosa PUPa3 0.43 DQ20_RS50570 hisF;go_function=imidazoleglycerol-phosphate imidazole glycerol phosphate synthase subunit HisF 0.27 DQ20_RS33430 pabC;go_function=4-amino-4-deoxychorismate aminodeoxychorismate lyase low > 101
Pseudomonas aeruginosa MRSN321 0.43 DY961_RS11530 hisF;go_function=imidazoleglycerol-phosphate imidazole glycerol phosphate synthase subunit HisF 0.27 DY961_RS02155 pabC;go_function=4-amino-4-deoxychorismate aminodeoxychorismate lyase low > 100
Pseudomonas aeruginosa PA14 0.43 IKLFDK_27805 Imidazole glycerol phosphate synthase subunit HisF 0.28 IKLFDK_15080 aminodeoxychorismate lyase — —
Pseudomonas stutzeri RCH2 0.42 Psest_0156 imidazoleglycerol phosphate synthase, cyclase subunit 0.27 Psest_1691 aminodeoxychorismate lyase — —
Pseudomonas sp. BP01 0.42 JOY50_RS25520 hisF imidazole glycerol phosphate synthase subunit HisF 0.24 JOY50_RS16775 pabC aminodeoxychorismate lyase low > 84
Pseudomonas putida KT2440 0.42 PP_0293 Imidazole glycerol phosphate synthase subunit HisF 0.23 PP_1917 4-amino-4-deoxychorismate lyase low > 96
Caulobacter crescentus NA1000 Δfur 0.41 CCNA_03853 imidazole glycerol phosphate synthase, cyclase subunit 0.16 CCNA_03047 4-amino-4-deoxychorismate lyase low > 67
Caulobacter crescentus NA1000 0.41 CCNA_03853 imidazole glycerol phosphate synthase, cyclase subunit 0.16 CCNA_03047 4-amino-4-deoxychorismate lyase low > 66
Pseudomonas fluorescens FW300-N2E3 0.41 AO353_12090 imidazole glycerol phosphate synthase subunit HisF 0.24 AO353_01350 4-amino-4-deoxychorismate lyase low > 101
Acinetobacter baumannii LAC-4 0.41 RR41_RS01295 imidazole glycerol phosphate synthase subunit HisF 0.24 RR41_RS04800 aminodeoxychorismate lyase low > 55
Pseudomonas syringae pv. syringae B728a ΔmexB 0.41 Psyr_4893 imidazole glycerol phosphate synthase subunit hisF 0.25 Psyr_1650 aminodeoxychorismate lyase apoprotein — —
Pseudomonas syringae pv. syringae B728a 0.41 Psyr_4893 imidazole glycerol phosphate synthase subunit hisF 0.25 Psyr_1650 aminodeoxychorismate lyase apoprotein low > 86
Pseudomonas simiae WCS417 0.41 PS417_01580 imidazole glycerol phosphate synthase 0.25 PS417_21425 4-amino-4-deoxychorismate lyase low > 88
Marinobacter adhaerens HP15 0.41 HP15_3009 protein containing histidine biosynthesis, HisF domain 0.17 HP15_2209 4-amino-4-deoxychorismate lyase — —
Pseudomonas sp. SVBP6 0.41 COO64_RS00210 hisF imidazole glycerol phosphate synthase subunit HisF 0.25 COO64_RS05790 pabC aminodeoxychorismate lyase low > 93
Pseudomonas sp. RS175 0.41 PFR28_04933 Imidazole glycerol phosphate synthase subunit HisF 0.26 PFR28_03007 Aminodeoxychorismate lyase low > 88
Pseudomonas fluorescens GW456-L13 0.41 PfGW456L13_358 Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) 0.26 PfGW456L13_2108 Aminodeoxychorismate lyase (EC 4.1.3.38) low > 87
Methylophilus sp. DMC18 0.41 GFF1568 Imidazole glycerol phosphate synthase subunit HisF 0.29 GFF627 Aminodeoxychorismate lyase — —
Pseudomonas sp. DMC3 0.41 GFF4095 Imidazole glycerol phosphate synthase subunit HisF 0.26 GFF4754 Aminodeoxychorismate lyase low > 89
Pseudomonas fluorescens SBW25 0.41 PFLU_RS01625 imidazole glycerol phosphate synthase subunit HisF 0.26 PFLU_RS23040 aminodeoxychorismate lyase low > 109
Pseudomonas fluorescens SBW25-INTG 0.41 PFLU_RS01625 imidazole glycerol phosphate synthase subunit HisF 0.26 PFLU_RS23040 aminodeoxychorismate lyase low > 109
Pseudomonas fluorescens FW300-N1B4 0.41 Pf1N1B4_1623 Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) 0.24 Pf1N1B4_448 Aminodeoxychorismate lyase (EC 4.1.3.38) — —
Pseudomonas lactucae CFBP13502 0.41 GEMAOFIL_00536 Imidazole glycerol phosphate synthase subunit HisF 0.25 GEMAOFIL_04429 Aminodeoxychorismate lyase low > 96
Pseudomonas fluorescens FW300-N2C3 0.41 AO356_09795 imidazole glycerol phosphate synthase subunit HisF 0.26 AO356_20180 4-amino-4-deoxychorismate lyase low > 104
Pseudomonas fluorescens FW300-N2E2 0.41 Pf6N2E2_3838 Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) 0.25 Pf6N2E2_5955 Aminodeoxychorismate lyase (EC 4.1.3.38) — —
Acinetobacter radioresistens SK82 0.40 MPMX26_02854 Imidazole glycerol phosphate synthase subunit HisF 0.28 MPMX26_02165 Aminodeoxychorismate lyase low > 36
Pseudomonas orientalis W4I3 0.40 QF045_RS04650 imidazole glycerol phosphate synthase subunit HisF 0.26 QF045_RS23505 aminodeoxychorismate lyase low > 93
Pseudomonas segetis P6 0.40 MPMX49_04299 Imidazole glycerol phosphate synthase subunit HisF 0.28 MPMX49_02083 Aminodeoxychorismate lyase low > 75
Kangiella aquimarina DSM 16071 0.39 B158DRAFT_2291 imidazoleglycerol phosphate synthase, cyclase subunit 0.22 B158DRAFT_1750 aminodeoxychorismate lyase low > 40
Azospirillum sp. SherDot2 0.39 MPMX19_02542 Imidazole glycerol phosphate synthase subunit HisF 0.17 MPMX19_04995 D-alanine aminotransferase — —
Synechocystis sp000284455 PCC 6803 0.37 SGL_RS10250 imidazole glycerol phosphate synthase subunit HisF 0.12 SGL_RS07250 aminotransferase class IV — —
Agrobacterium fabrum C58 0.34 Atu0039 imidazoleglycerol-phosphate synthase cyclase 0.13 Atu5473 D-alanine aminotransferase low > 89
Xanthobacter sp. DMC5 0.32 GFF2417 Imidazole glycerol phosphate synthase subunit HisF 0.19 GFF438 D-alanine aminotransferase — —

Not shown: 47 genomes with orthologs for CSW01_05775 only; 2 genomes with orthologs for CSW01_10080 only