Conservation of cofitness between CSW01_13560 and CSW01_04650 in Vibrio cholerae E7946 ATCC 55056

63 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_13560 methylenetetrahydrofolate reductase 1.0 CSW01_04650 D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase 0.64 14
Dickeya dianthicola 67-19 0.80 HGI48_RS20415 methylenetetrahydrofolate reductase 0.66 HGI48_RS16910 D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase
Dickeya dianthicola ME23 0.79 DZA65_RS21460 methylenetetrahydrofolate reductase 0.66 DZA65_RS17985 D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase low > 75
Enterobacter sp. TBS_079 0.79 MPMX20_04529 5,10-methylenetetrahydrofolate reductase 0.66 MPMX20_00884 D-glycero-beta-D-manno-heptose-1,7-bisphosphate 7-phosphatase
Escherichia coli ECRC101 0.79 MCAODC_04165 metF methylenetetrahydrofolate reductase 0.64 MCAODC_00560 gmhB D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase
Escherichia coli ECRC102 0.79 NIAGMN_11420 metF methylenetetrahydrofolate reductase 0.64 NIAGMN_07895 gmhB D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase low > 80
Escherichia coli BL21 0.79 ECD_03827 5,10-methylenetetrahydrofolate reductase 0.64 ECD_00199 D,D-heptose 1,7-bisphosphate phosphatase
Escherichia coli ECRC98 0.79 JDDGAC_17290 metF methylenetetrahydrofolate reductase 0.64 JDDGAC_13640 gmhB D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase low > 87
Escherichia coli ECRC100 0.79 OKFHMN_13665 metF methylenetetrahydrofolate reductase 0.64 OKFHMN_10045 gmhB D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase low > 79
Escherichia coli BW25113 0.79 b3941 metF 5,10-methylenetetrahydrofolate reductase (NCBI) 0.64 b0200 gmhB hypothetical protein (NCBI) low > 76
Escherichia coli ECOR27 0.79 NOLOHH_05810 metF methylenetetrahydrofolate reductase 0.64 NOLOHH_02390 gmhB D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase low > 76
Escherichia coli HS(pFamp)R (ATCC 700891) 0.79 OHPLBJKB_04109 5,10-methylenetetrahydrofolate reductase 0.64 OHPLBJKB_03461 D-glycero-beta-D-manno-heptose-1,7-bisphosphate 7-phosphatase low > 74
Enterobacter asburiae PDN3 0.79 EX28DRAFT_4413 5,10-methylenetetrahydrofolate reductase, prokaryotic form 0.65 EX28DRAFT_3788 D,D-heptose 1,7-bisphosphate phosphatase
Escherichia coli ECRC99 0.79 KEDOAH_14495 metF methylenetetrahydrofolate reductase 0.64 KEDOAH_18110 gmhB D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase
Escherichia coli ECRC62 0.79 BNILDI_05725 metF methylenetetrahydrofolate reductase 0.64 BNILDI_09280 gmhB D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase
Pantoea agglomerans CFBP13505 P0401 0.78 PagCFBP13505_RS18450 methylenetetrahydrofolate reductase 0.63 PagCFBP13505_RS13625 D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase
Escherichia coli ECOR38 0.78 HEPCGN_12310 metF methylenetetrahydrofolate reductase 0.64 HEPCGN_07985 gmhB D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase low > 88
Pantoea sp. MT58 0.78 IAI47_00890 methylenetetrahydrofolate reductase 0.63 IAI47_15380 D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase
Rahnella sp. WP5 0.78 EX31_RS14205 methylenetetrahydrofolate reductase 0.65 EX31_RS12875 D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase low > 89
Klebsiella michiganensis M5al 0.78 BWI76_RS00805 5,10-methylenetetrahydrofolate reductase 0.66 BWI76_RS05370 D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase
Escherichia fergusonii Becca 0.78 EFB2_04672 5,10-methylenetetrahydrofolate reductase 0.65 EFB2_03843 D-glycero-beta-D-manno-heptose-1,7-bisphosphate 7-phosphatase
Klebsiella pneumoniae MKP103 0.78 KDGMDA_09325 methylenetetrahydrofolate reductase 0.66 KDGMDA_13620 D-glycero-beta-D-manno-heptose 1 7-bisphosphate 7-phosphatase low > 95
Escherichia coli Nissle 1917 0.78 ECOLIN_RS22760 methylenetetrahydrofolate reductase 0.65 ECOLIN_RS26745 D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase
Erwinia amylovora T8 0.77 OLJFJH_06105 methylenetetrahydrofolate reductase 0.60 OLJFJH_00475 D-glycero-beta-D-manno-heptose 1 7-bisphosphate 7-phosphatase
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.77 GFF2329 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 0.64 GFF20 D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase (EC 3.1.1.-) low > 78
Pectobacterium carotovorum WPP14 0.76 HER17_RS00950 methylenetetrahydrofolate reductase 0.67 HER17_RS04385 D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase low > 75
Serratia liquefaciens MT49 0.76 IAI46_24530 methylenetetrahydrofolate reductase 0.66 IAI46_20070 D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase
Shewanella amazonensis SB2B 0.76 Sama_3169 metF 5,10-methylenetetrahydrofolate reductase (RefSeq) 0.71 Sama_1535 D,D-heptose 1,7-bisphosphate phosphatase (RefSeq)
Erwinia tracheiphila SCR3 0.75 LU632_RS19630 metF methylenetetrahydrofolate reductase 0.61 LU632_RS19815 gmhB D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase low > 73
Erwinia tracheiphila HP pepo 2.2 0.75 IJEDHG_13030 metF methylenetetrahydrofolate reductase 0.62 IJEDHG_15330 gmhB D-glycero-beta-D-manno-heptose 1 7-bisphosphate 7-phosphatase
Shewanella loihica PV-4 0.74 Shew_0522 metF 5,10-methylenetetrahydrofolate reductase (RefSeq) 0.71 Shew_2357 D,D-heptose 1,7-bisphosphate phosphatase (RefSeq) low > 60
Shewanella sp. ANA-3 0.73 Shewana3_3612 metF 5,10-methylenetetrahydrofolate reductase (RefSeq) 0.68 Shewana3_1583 D,D-heptose 1,7-bisphosphate phosphatase (RefSeq) low > 73
Shewanella oneidensis MR-1 0.73 SO4054 metF 5,10-methylenetetrahydrofolate reductase (NCBI ptt file) 0.67 SO2851 histidinol phosphatase domain protein (NCBI ptt file) low > 76
Azospirillum brasilense Sp245 0.51 AZOBR_RS09540 5 10-methylenetetrahydrofolate reductase 0.38 AZOBR_RS33755 D-glycero-D-manno-heptose 1 7-bisphosphate phosphatase low > 97
Burkholderia phytofirmans PsJN 0.35 BPHYT_RS18705 5,10-methylenetetrahydrofolate reductase 0.26 BPHYT_RS03340 D,D-heptose 1,7-bisphosphate phosphatase
Pseudomonas sp. BP01 0.35 JOY50_RS09810 metF methylenetetrahydrofolate reductase [NAD(P)H] 0.26 JOY50_RS08285 gmhB D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase
Pseudomonas putida KT2440 0.35 PP_4977 5,10-methylenetetrahydrofolate reductase 0.26 PP_0059 D-glycero-beta-D-manno-heptose-1,7-bisphosphate 7-phosphatase
Cupriavidus basilensis FW507-4G11 0.35 RR42_RS01385 5,10-methylenetetrahydrofolate reductase 0.29 RR42_RS02815 D,D-heptose 1,7-bisphosphate phosphatase
Dechlorosoma suillum PS 0.35 Dsui_0640 5,10-methylenetetrahydrofolate reductase 0.29 Dsui_1201 histidinol-phosphate phosphatase family protein
Pseudomonas sp. RS175 0.35 PFR28_04202 5,10-methylenetetrahydrofolate reductase 0.25 PFR28_04599 D-glycero-beta-D-manno-heptose-1,7-bisphosphate 7-phosphatase
Pseudomonas fluorescens FW300-N1B4 0.35 Pf1N1B4_2384 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 0.27 Pf1N1B4_1921 D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase (EC 3.1.1.-); Histidinol-phosphatase (EC 3.1.3.15)
Pseudomonas sp. DMC3 0.35 GFF171 5,10-methylenetetrahydrofolate reductase 0.26 GFF583 D-glycero-beta-D-manno-heptose-1,7-bisphosphate 7-phosphatase
Pseudomonas simiae WCS417 0.35 PS417_26510 5,10-methylenetetrahydrofolate reductase 0.26 PS417_00050 histidinol phosphatase
Pseudomonas sp. S08-1 0.35 OH686_10820 methylenetetrahydrofolate reductase [NAD(P)H] 0.23 OH686_12570 Histidinol-phosphatase
Pseudomonas fluorescens FW300-N2E2 0.35 Pf6N2E2_4638 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 0.25 Pf6N2E2_4191 D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase (EC 3.1.1.-); Histidinol-phosphatase (EC 3.1.3.15)
Pseudomonas orientalis W4I3 0.35 QF045_RS00905 methylenetetrahydrofolate reductase [NAD(P)H] 0.25 QF045_RS02985 D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase
Pseudomonas stutzeri RCH2 0.34 Psest_0313 5,10-methylenetetrahydrofolate reductase, prokaryotic form 0.26 Psest_0009 histidinol-phosphate phosphatase family domain/HAD-superfamily hydrolase, subfamily IIIA
Pseudomonas fluorescens SBW25-INTG 0.34 PFLU_RS28165 methylenetetrahydrofolate reductase [NAD(P)H] 0.26 PFLU_RS00045 D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase
Pseudomonas fluorescens FW300-N2C3 0.34 AO356_13605 5,10-methylenetetrahydrofolate reductase 0.25 AO356_11605 histidinol phosphatase
Pseudomonas segetis P6 0.34 MPMX49_00645 5,10-methylenetetrahydrofolate reductase 0.25 MPMX49_00264 D-glycero-beta-D-manno-heptose-1,7-bisphosphate 7-phosphatase
Pseudomonas fluorescens FW300-N2E3 0.34 AO353_08015 5,10-methylenetetrahydrofolate reductase 0.25 AO353_10590 histidinol phosphatase
Pseudomonas fluorescens SBW25 0.34 PFLU_RS28165 methylenetetrahydrofolate reductase [NAD(P)H] 0.26 PFLU_RS00045 D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase
Pseudomonas sp. SVBP6 0.34 COO64_RS17485 metF methylenetetrahydrofolate reductase [NAD(P)H] 0.25 COO64_RS02180 gmhB D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase
Pseudomonas aeruginosa PUPa3 0.34 DQ20_RS37170 metF;go_function=methylenetetrahydrofolate methylenetetrahydrofolate reductase [NAD(P)H] 0.26 DQ20_RS58635 gmhB;go_function=phosphatase D-glycero-beta-D-manno-heptose 1 7-bisphosphate 7-phosphatase
Pseudomonas aeruginosa MRSN321 0.34 DY961_RS22135 metF;go_function=methylenetetrahydrofolate methylenetetrahydrofolate reductase [NAD(P)H] 0.26 DY961_RS26230 gmhB;go_function=phosphatase D-glycero-beta-D-manno-heptose 1 7-bisphosphate 7-phosphatase
Pseudomonas aeruginosa PA14 0.34 IKLFDK_23270 methylenetetrahydrofolate reductase [NAD(P)H] 0.26 IKLFDK_25530 D-glycero-beta-D-manno-heptose 1 7-bisphosphate 7-phosphatase
Methylophilus sp. DMC18 0.34 GFF1492 5,10-methylenetetrahydrofolate reductase 0.26 GFF2588 D-glycero-beta-D-manno-heptose-1,7-bisphosphate 7-phosphatase
Pseudomonas lactucae CFBP13502 0.34 GEMAOFIL_05433 5,10-methylenetetrahydrofolate reductase 0.26 GEMAOFIL_00216 D-glycero-beta-D-manno-heptose-1,7-bisphosphate 7-phosphatase
Pseudomonas fluorescens GW456-L13 0.34 PfGW456L13_1050 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 0.26 PfGW456L13_660 D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase (EC 3.1.1.-); Histidinol-phosphatase (EC 3.1.3.15)
Pseudomonas syringae pv. syringae B728a 0.33 Psyr_0459 5,10-methylenetetrahydrofolate reductase 0.24 Psyr_0010 D-alpha,beta-D-heptose 1,7-bisphosphate phosphatase
Pseudomonas syringae pv. syringae B728a ΔmexB 0.33 Psyr_0459 5,10-methylenetetrahydrofolate reductase 0.24 Psyr_0010 D-alpha,beta-D-heptose 1,7-bisphosphate phosphatase
Herbaspirillum seropedicae SmR1 0.32 HSERO_RS21425 5,10-methylenetetrahydrofolate reductase 0.33 HSERO_RS22085 D,D-heptose 1,7-bisphosphate phosphatase low > 78
Pedobacter sp. GW460-11-11-14-LB5 0.20 CA265_RS23445 methylenetetrahydrofolate reductase [NAD(P)H] 0.30 CA265_RS08680 histidinol phosphate phosphatase low > 88
Mucilaginibacter yixingensis YX-36 DSM 26809 0.20 ABZR88_RS20935 methylenetetrahydrofolate reductase [NAD(P)H] 0.34 ABZR88_RS06900 HAD-IIIA family hydrolase low > 71

Not shown: 55 genomes with orthologs for CSW01_13560 only; 0 genomes with orthologs for CSW01_04650 only