Conservation of cofitness between CSW01_04590 and CSW01_02060 in Vibrio cholerae E7946 ATCC 55056

67 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_04590 transcriptional regulator GcvA 1.0 CSW01_02060 methionine synthase 0.57 11
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.73 GFF4865 Glycine cleavage system transcriptional activator GcvA 0.76 GFF1358 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) low > 78
Serratia liquefaciens MT49 0.72 IAI46_20340 transcriptional regulator GcvA 0.75 IAI46_23155 methionine synthase low > 87
Rahnella sp. WP5 0.72 EX31_RS13110 transcriptional regulator GcvA 0.75 EX31_RS11760 methionine synthase low > 89
Shewanella amazonensis SB2B 0.72 Sama_2429 DNA-binding transcriptional activator GcvA (RefSeq) 0.67 Sama_0758 metH B12-dependent methionine synthase (RefSeq) low > 62
Escherichia coli ECRC101 0.72 MCAODC_10645 gcvA glycine cleavage system transcriptional regulator GcvA 0.76 MCAODC_03740 metH methionine synthase low > 87
Escherichia coli HS(pFamp)R (ATCC 700891) 0.72 OHPLBJKB_00923 Glycine cleavage system transcriptional activator 0.76 OHPLBJKB_04030 Methionine synthase low > 74
Escherichia coli ECRC102 0.72 NIAGMN_17890 gcvA glycine cleavage system transcriptional regulator GcvA 0.76 NIAGMN_10990 metH methionine synthase low > 80
Escherichia coli Nissle 1917 0.72 ECOLIN_RS15650 glycine cleavage system transcriptional regulator GcvA 0.75 ECOLIN_RS23160 methionine synthase low > 55
Escherichia coli ECRC99 0.72 KEDOAH_08010 gcvA glycine cleavage system transcriptional regulator GcvA 0.76 KEDOAH_14920 metH methionine synthase — —
Escherichia coli ECOR38 0.72 HEPCGN_19375 gcvA glycine cleavage system transcriptional regulator GcvA 0.76 HEPCGN_11885 metH methionine synthase low > 88
Escherichia coli ECRC98 0.72 JDDGAC_23785 gcvA glycine cleavage system transcriptional regulator GcvA 0.75 JDDGAC_16865 metH methionine synthase low > 87
Escherichia fergusonii Becca 0.72 EFB2_01109 Glycine cleavage system transcriptional activator 0.75 EFB2_04592 Methionine synthase low > 86
Escherichia coli ECRC100 0.72 OKFHMN_20120 gcvA glycine cleavage system transcriptional regulator GcvA 0.76 OKFHMN_13240 metH methionine synthase low > 79
Escherichia coli BL21 0.72 ECD_02659 glycine cleavage system transcriptional activator; autorepressor 0.76 ECD_03891 homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent low > 61
Escherichia coli ECRC62 0.72 BNILDI_10505 gcvA glycine cleavage system transcriptional regulator GcvA 0.76 BNILDI_06140 metH methionine synthase low > 75
Escherichia coli BW25113 0.72 b2808 gcvA DNA-binding transcriptional dual regulator (NCBI) 0.76 b4019 metH B12-dependent methionine synthase (NCBI) low > 76
Escherichia coli ECOR27 0.72 NOLOHH_12000 gcvA glycine cleavage system transcriptional regulator GcvA 0.76 NOLOHH_05380 metH methionine synthase low > 76
Enterobacter sp. TBS_079 0.71 MPMX20_03671 Glycine cleavage system transcriptional activator 0.75 MPMX20_00235 Methionine synthase 0.29 25
Pantoea sp. MT58 0.71 IAI47_04025 transcriptional regulator GcvA 0.75 IAI47_17990 methionine synthase low > 76
Klebsiella michiganensis M5al 0.71 BWI76_RS22955 transcriptional regulator GcvA 0.76 BWI76_RS01685 methionine synthase low > 92
Dickeya dadantii 3937 0.71 DDA3937_RS05050 transcriptional regulator GcvA 0.76 DDA3937_RS19040 methionine synthase low > 74
Pantoea agglomerans CFBP13505 P0401 0.71 PagCFBP13505_RS16945 transcriptional regulator GcvA 0.76 PagCFBP13505_RS22305 methionine synthase low > 74
Dickeya dianthicola ME23 0.71 DZA65_RS05390 transcriptional regulator GcvA 0.75 DZA65_RS20250 methionine synthase 0.46 5
Enterobacter asburiae PDN3 0.71 EX28DRAFT_2883 Transcriptional regulator 0.76 EX28DRAFT_4326 methionine synthase (B12-dependent) (EC 2.1.1.13) low > 76
Shewanella sp. ANA-3 0.71 Shewana3_2894 DNA-binding transcriptional activator GcvA (RefSeq) 0.66 Shewana3_3282 metH B12-dependent methionine synthase (RefSeq) — —
Dickeya dianthicola 67-19 0.71 HGI48_RS05050 transcriptional regulator GcvA 0.75 HGI48_RS19130 methionine synthase low > 71
Shewanella loihica PV-4 0.71 Shew_2764 DNA-binding transcriptional activator GcvA (RefSeq) 0.65 Shew_0710 metH B12-dependent methionine synthase (RefSeq) — —
Pectobacterium carotovorum WPP14 0.71 HER17_RS16415 transcriptional regulator GcvA 0.76 HER17_RS02310 methionine synthase low > 75
Shewanella oneidensis MR-1 0.70 SO1533 glycine cleavage system transcriptional activator, putative (NCBI ptt file) 0.66 SO1030 metH 5-methyltetrahydrofolate--homocysteine methyltransferase (NCBI ptt file) low > 76
Klebsiella pneumoniae MKP103 0.63 KDGMDA_03515 Glycine cleavage system transcriptional activator 0.76 KDGMDA_10165 methionine synthase low > 95
Kangiella aquimarina DSM 16071 0.53 B158DRAFT_0909 Transcriptional regulator 0.66 B158DRAFT_2466 methionine synthase (B12-dependent) (EC 2.1.1.13) low > 40
Azospirillum sp. SherDot2 0.44 MPMX19_01055 Glycine cleavage system transcriptional activator 0.21 MPMX19_00637 Methionine synthase — —
Pseudomonas fluorescens FW300-N2E2 0.37 Pf6N2E2_1560 Glycine cleavage system transcriptional activator GcvA 0.64 Pf6N2E2_2068 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) low > 103
Rhodospirillum rubrum S1H 0.37 Rru_A2214 Transcriptional Regulator, LysR family (NCBI) 0.21 Rru_A1531 5-methyltetrahydrofolate--homocysteine methyltransferase (NCBI) — —
Agrobacterium fabrum C58 0.34 Atu2078 transcriptional regulator, LysR family 0.59 Atu2155 methionine synthase low > 89
Pseudomonas sp. SVBP6 0.34 COO64_RS14470 gcvA transcriptional regulator GcvA 0.64 COO64_RS24910 metH methionine synthase low > 93
Pseudomonas fluorescens FW300-N2C3 0.31 AO356_15125 LysR family transcriptional regulator 0.64 AO356_00545 methionine synthase low > 104
Pseudomonas aeruginosa PA14 0.31 IKLFDK_23190 LysR family transcriptional regulator 0.66 IKLFDK_08975 methionine synthase low > 98
Pseudomonas sp. RS175 0.31 PFR28_04727 Glycine cleavage system transcriptional activator 0.64 PFR28_01369 Methionine synthase low > 88
Pseudomonas aeruginosa PUPa3 0.31 DQ20_RS37090 LysR family transcriptional regulator 0.66 DQ20_RS55030 metH;go_function=zinc methionine synthase low > 101
Pseudomonas aeruginosa MRSN321 0.31 DY961_RS22230 LysR family transcriptional regulator 0.66 DY961_RS20955 metH;go_function=zinc methionine synthase low > 100
Pseudomonas sp. S08-1 0.31 OH686_11695 Transcriptional regulator, LysR family 0.65 OH686_03335 methionine synthase low > 80
Pseudomonas lactucae CFBP13502 0.30 GEMAOFIL_02417 Glycine cleavage system transcriptional activator 0.64 GEMAOFIL_02709 Methionine synthase low > 96
Pseudomonas sp. BP01 0.30 JOY50_RS09180 LysR family transcriptional regulator 0.65 JOY50_RS10720 metH methionine synthase low > 84
Pseudomonas putida KT2440 0.30 PP_0661 putative Transcriptional regulator AmpR 0.65 PP_2375 cobalamin-dependent methionine synthase low > 96
Rhizobium sp. OAE497 0.30 ABIE40_RS01615 transcriptional regulator GcvA 0.59 ABIE40_RS12135 methionine synthase low > 107
Pseudomonas simiae WCS417 0.30 PS417_23350 LysR family transcriptional regulator 0.64 PS417_12310 methionine synthase low > 88
Pseudomonas stutzeri RCH2 0.30 Psest_2739 Transcriptional regulator 0.66 Psest_2102 5-methyltetrahydrofolate--homocysteine methyltransferase low > 67
Pseudomonas fluorescens SBW25 0.30 PFLU_RS25165 LysR family transcriptional regulator 0.65 PFLU_RS13000 methionine synthase low > 109
Pseudomonas fluorescens SBW25-INTG 0.30 PFLU_RS25165 LysR family transcriptional regulator 0.65 PFLU_RS13000 methionine synthase low > 109
Magnetospirillum magneticum AMB-1 0.30 AMB_RS04220 transcriptional regulator GcvA 0.21 AMB_RS02225 methionine synthase — —
Pseudomonas fluorescens FW300-N1B4 0.30 Pf1N1B4_1817 Glycine cleavage system transcriptional activator 0.64 Pf1N1B4_5661 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) low > 87
Pseudomonas segetis P6 0.29 ACVTMO_RS01970 LysR family transcriptional regulator 0.65 ACVTMO_RS12855 metH methionine synthase low > 75
Pseudomonas syringae pv. syringae B728a ΔmexB 0.29 Psyr_5015 transcriptional regulator, LysR family 0.64 Psyr_2464 methionine synthase (B12-dependent) low > 86
Pseudomonas syringae pv. syringae B728a 0.29 Psyr_5015 transcriptional regulator, LysR family 0.64 Psyr_2464 methionine synthase (B12-dependent) low > 86
Pseudomonas fluorescens GW456-L13 0.29 PfGW456L13_555 Glycine cleavage system transcriptional activator 0.64 PfGW456L13_2847 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) low > 87
Pseudomonas sp. DMC3 0.29 GFF687 Glycine cleavage system transcriptional activator 0.65 GFF3687 Methionine synthase low > 89
Pseudomonas fluorescens FW300-N2E3 0.29 AO353_15505 LysR family transcriptional regulator 0.64 AO353_21615 methionine synthase low > 101
Herbaspirillum seropedicae SmR1 0.28 HSERO_RS07925 LysR family transcriptional regulator 0.61 HSERO_RS21740 methionine synthase low > 78
Sinorhizobium meliloti 1021 0.28 SMa0179 LysR family transcriptional regulator 0.59 SMc03112 B12-dependent methionine synthase low > 103
Dechlorosoma suillum PS 0.27 Dsui_2033 transcriptional regulator 0.63 Dsui_0779 5-methyltetrahydrofolate--homocysteine methyltransferase — —
Acinetobacter radioresistens SK82 0.27 MPMX26_01927 Glycine cleavage system transcriptional activator 0.62 MPMX26_02351 Methionine synthase — —
Castellaniella sp019104865 MT123 0.27 ABCV34_RS01790 LysR substrate-binding domain-containing protein 0.57 ABCV34_RS14560 methionine synthase low > 48
Marinobacter adhaerens HP15 0.24 HP15_1669 transcriptional regulator, LysR family protein 0.63 HP15_1792 B12-dependent methionine synthase low > 73
Acinetobacter baumannii LAC-4 0.24 RR41_RS15665 LysR family transcriptional regulator 0.62 RR41_RS08790 methionine synthase low > 55
Rhodopseudomonas palustris CGA009 0.23 TX73_013680 LysR substrate-binding domain-containing protein 0.60 TX73_019180 methionine synthase low > 86
Xanthobacter sp. DMC5 0.22 GFF4114 HTH-type transcriptional regulator TrpI 0.61 GFF4146 Methionine synthase — —

Not shown: 36 genomes with orthologs for CSW01_04590 only; 9 genomes with orthologs for CSW01_02060 only