Conservation of cofitness between CSW01_12610 and CSW01_01875 in Vibrio cholerae E7946 ATCC 55056

64 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_12610 3-isopropylmalate dehydratase small subunit 1.0 CSW01_01875 hypothetical protein 0.75 3
Serratia liquefaciens MT49 0.78 IAI46_03340 3-isopropylmalate dehydratase small subunit 0.66 IAI46_23490 transcriptional regulator low > 87
Dickeya dadantii 3937 0.78 DDA3937_RS18130 3-isopropylmalate dehydratase small subunit 0.66 DDA3937_RS19340 transcriptional regulator low > 74
Pectobacterium carotovorum WPP14 0.77 HER17_RS03070 3-isopropylmalate dehydratase small subunit 0.65 HER17_RS02010 transcriptional regulator low > 75
Dickeya dianthicola ME23 0.76 DZA65_RS19215 3-isopropylmalate dehydratase small subunit 0.66 DZA65_RS20560 transcriptional regulator low > 75
Dickeya dianthicola 67-19 0.76 HGI48_RS18070 3-isopropylmalate dehydratase small subunit 0.66 HGI48_RS19440 transcriptional regulator low > 71
Klebsiella pneumoniae MKP103 0.75 KDGMDA_12895 3-isopropylmalate dehydratase small subunit 0.64 KDGMDA_06760 Uncharacterized protein YheO low > 95
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.74 GFF167 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) 0.64 GFF3726 YheO-like PAS domain low > 78
Pantoea agglomerans CFBP13505 P0401 0.74 PagCFBP13505_RS12985 3-isopropylmalate dehydratase small subunit 0.65 PagCFBP13505_RS21525 transcriptional regulator low > 74
Enterobacter asburiae PDN3 0.74 EX28DRAFT_3667 3-isopropylmalate dehydratase, small subunit 0.64 EX28DRAFT_4184 Uncharacterized protein conserved in bacteria low > 76
Escherichia coli HS(pFamp)R (ATCC 700891) 0.73 OHPLBJKB_03586 3-isopropylmalate dehydratase small subunit 0.64 OHPLBJKB_00357 Transcriptional regulator DauR low > 74
Pantoea sp. MT58 0.73 IAI47_16015 3-isopropylmalate dehydratase small subunit 0.65 IAI47_02055 transcriptional regulator low > 76
Klebsiella michiganensis M5al 0.73 BWI76_RS04665 3-isopropylmalate dehydratase small subunit 0.64 BWI76_RS25905 hypothetical protein low > 92
Rahnella sp. WP5 0.73 EX31_RS03695 3-isopropylmalate dehydratase small subunit 0.66 EX31_RS04470 transcriptional regulator low > 89
Escherichia coli Nissle 1917 0.72 ECOLIN_RS00385 3-isopropylmalate dehydratase small subunit 0.64 ECOLIN_RS19165 transcriptional regulator low > 55
Escherichia coli ECRC62 0.72 BNILDI_08535 leuD 3-isopropylmalate dehydratase small subunit 0.64 BNILDI_02420 yheO Uncharacterized protein YheO low > 75
Escherichia coli ECOR27 0.72 NOLOHH_03075 leuD 3-isopropylmalate dehydratase small subunit 0.64 NOLOHH_09100 yheO Uncharacterized protein YheO low > 76
Escherichia coli BW25113 0.72 b0071 leuD isopropylmalate isomerase small subunit (NCBI) 0.64 b3346 yheO orf, hypothetical protein (VIMSS) low > 76
Escherichia fergusonii Becca 0.72 EFB2_03974 3-isopropylmalate dehydratase small subunit 0.64 EFB2_00477 Transcriptional regulator DauR low > 86
Escherichia coli ECOR38 0.72 HEPCGN_08710 leuD 3-isopropylmalate dehydratase small subunit 0.64 HEPCGN_16130 yheO Uncharacterized protein YheO low > 88
Escherichia coli BL21 0.72 ECD_00073 3-isopropylmalate dehydratase small subunit 0.64 ECD_03197 putative PAS domain-containing DNA-binding transcriptional regulator low > 61
Escherichia coli ECRC101 0.72 MCAODC_01245 leuD 3-isopropylmalate dehydratase small subunit 0.64 MCAODC_07830 yheO Uncharacterized protein YheO low > 87
Escherichia coli ECRC102 0.72 NIAGMN_08580 leuD 3-isopropylmalate dehydratase small subunit 0.64 NIAGMN_15070 yheO Uncharacterized protein YheO low > 80
Escherichia coli ECRC98 0.72 JDDGAC_14325 leuD 3-isopropylmalate dehydratase small subunit 0.64 JDDGAC_20930 yheO Uncharacterized protein YheO low > 87
Escherichia coli ECRC100 0.72 OKFHMN_10730 leuD 3-isopropylmalate dehydratase small subunit 0.64 OKFHMN_17300 yheO Uncharacterized protein YheO low > 79
Escherichia coli ECRC99 0.72 KEDOAH_17425 leuD 3-isopropylmalate dehydratase small subunit 0.64 KEDOAH_10840 yheO Uncharacterized protein YheO — —
Enterobacter sp. TBS_079 0.71 MPMX20_00766 3-isopropylmalate dehydratase small subunit 1 0.64 MPMX20_04239 Transcriptional regulator DauR low > 85
Shewanella oneidensis MR-1 0.65 SO4233 leuD 3-isopropylmalate dehydratase, small subunit (NCBI ptt file) 0.35 SO1402 conserved hypothetical protein (NCBI ptt file) low > 76
Erwinia tracheiphila HP pepo 2.2 0.65 IJEDHG_06010 leuD 3-isopropylmalate dehydratase small subunit 0.66 IJEDHG_12210 Uncharacterized protein YheO — —
Erwinia tracheiphila SCR3 0.65 LU632_RS02865 leuD 3-isopropylmalate dehydratase small subunit 0.66 LU632_RS22710 transcriptional regulator low > 73
Erwinia amylovora T8 0.64 OLJFJH_01300 3-isopropylmalate dehydratase small subunit 0.66 OLJFJH_03930 Uncharacterized protein YheO low > 58
Shewanella sp. ANA-3 0.64 Shewana3_3758 leuD isopropylmalate isomerase small subunit (RefSeq) 0.35 Shewana3_2973 YheO domain-containing protein (RefSeq) low > 73
Pseudomonas simiae WCS417 0.61 PS417_18595 3-isopropylmalate dehydratase 0.15 PS417_12915 DNA-binding protein low > 88
Pseudomonas sp. SVBP6 0.60 COO64_RS05660 leuD 3-isopropylmalate dehydratase small subunit 0.15 COO64_RS25095 transcriptional regulator low > 93
Pseudomonas fluorescens SBW25 0.60 PFLU_RS20575 3-isopropylmalate dehydratase small subunit 0.15 PFLU_RS13585 DNA-binding protein low > 109
Pseudomonas fluorescens SBW25-INTG 0.60 PFLU_RS20575 3-isopropylmalate dehydratase small subunit 0.15 PFLU_RS13585 DNA-binding protein low > 109
Pseudomonas putida KT2440 0.60 PP_1986 3-isopropylmalate dehydratase small subunit 0.16 PP_2931 conserved protein of unknown function low > 96
Pseudomonas sp. S08-1 0.60 OH686_04475 3-isopropylmalate dehydratase small subunit 0.14 OH686_07030 YheO-like PAS domain low > 80
Pseudomonas sp. BP01 0.60 JOY50_RS16625 leuD 3-isopropylmalate dehydratase small subunit 0.16 JOY50_RS24520 transcriptional regulator low > 84
Pseudomonas fluorescens FW300-N1B4 0.59 Pf1N1B4_14 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) 0.15 Pf1N1B4_923 YheO-like PAS domain — —
Pseudomonas sp. DMC3 0.59 GFF786 3-isopropylmalate dehydratase small subunit 1 0.15 GFF1929 Transcriptional regulator DauR low > 89
Pseudomonas aeruginosa PUPa3 0.59 DQ20_RS34230 leuD;go_component=3-isopropylmalate 3-isopropylmalate dehydratase small subunit 0.15 DQ20_RS48840 dauR;inference=COORDINATES transcriptional regulator DauR low > 101
Pseudomonas fluorescens GW456-L13 0.59 PfGW456L13_3947 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) 0.16 PfGW456L13_1693 YheO-like PAS domain low > 87
Pseudomonas aeruginosa MRSN321 0.59 DY961_RS01325 leuD;go_component=3-isopropylmalate 3-isopropylmalate dehydratase small subunit 0.15 DY961_RS13545 dauR;inference=COORDINATES transcriptional regulator DauR low > 100
Pseudomonas aeruginosa PA14 0.59 IKLFDK_15875 3-isopropylmalate dehydratase small subunit 0.15 IKLFDK_19905 Transcriptional regulator DauR low > 98
Pseudomonas sp. RS175 0.59 PFR28_02823 3-isopropylmalate dehydratase small subunit 1 0.13 PFR28_03547 Transcriptional regulator DauR low > 88
Pseudomonas fluorescens FW300-N2E2 0.59 Pf6N2E2_64 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) 0.14 Pf6N2E2_5396 YheO-like PAS domain low > 103
Pseudomonas fluorescens FW300-N2E3 0.59 AO353_20625 3-isopropylmalate dehydratase 0.16 AO353_04640 hypothetical protein low > 101
Pseudomonas fluorescens FW300-N2C3 0.58 AO356_21405 3-isopropylmalate dehydratase 0.14 AO356_17355 hypothetical protein low > 104
Paraburkholderia bryophila 376MFSha3.1 0.58 H281DRAFT_06073 3-isopropylmalate dehydratase, small subunit 0.12 H281DRAFT_05884 Predicted transcriptional regulator YheO, contains PAS and DNA-binding HTH domains low > 103
Burkholderia phytofirmans PsJN 0.57 BPHYT_RS33905 3-isopropylmalate dehydratase small subunit 0.13 BPHYT_RS28105 hypothetical protein — —
Paraburkholderia sabiae LMG 24235 0.57 QEN71_RS17615 3-isopropylmalate dehydratase small subunit 0.15 QEN71_RS18565 PAS domain-containing protein low > 153
Ralstonia solanacearum PSI07 0.57 RPSI07_RS14700 3-isopropylmalate dehydratase small subunit 0.15 RPSI07_RS06825 DNA-binding protein — —
Ralstonia solanacearum UW163 0.57 UW163_RS11110 3-isopropylmalate dehydratase small subunit 0.16 UW163_RS17980 DNA-binding protein — —
Ralstonia solanacearum IBSBF1503 0.57 RALBFv3_RS02615 3-isopropylmalate dehydratase small subunit 0.16 RALBFv3_RS16625 DNA-binding protein low > 76
Paraburkholderia graminis OAS925 0.56 ABIE53_004803 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit 0.12 ABIE53_005722 putative transcriptional regulator YheO low > 113
Cupriavidus basilensis FW507-4G11 0.56 RR42_RS24180 3-isopropylmalate dehydratase 0.14 RR42_RS11120 DNA-binding protein low > 128
Ralstonia solanacearum GMI1000 0.56 RS_RS09995 3-isopropylmalate dehydratase small subunit 0.16 RS_RS24435 DNA-binding protein — —
Ralstonia sp. UNC404CL21Col 0.56 ABZR87_RS14535 3-isopropylmalate dehydratase small subunit 0.15 ABZR87_RS17665 PAS domain-containing protein low > 80
Herbaspirillum seropedicae SmR1 0.55 HSERO_RS16505 3-isopropylmalate dehydratase small subunit 0.14 HSERO_RS01425 DNA-binding protein low > 78
Acinetobacter baumannii LAC-4 0.55 RR41_RS16895 3-isopropylmalate dehydratase small subunit 0.18 RR41_RS05440 PAS domain-containing protein low > 55
Variovorax sp. SCN45 0.55 GFF3889 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) 0.12 GFF2493 YheO-like PAS domain low > 127
Acidovorax sp. GW101-3H11 0.52 Ac3H11_1527 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) 0.15 Ac3H11_38 YheO-like PAS domain low > 79
Rhizobium sp. OAE497 0.49 ABIE40_RS19040 3-isopropylmalate dehydratase small subunit 0.16 ABIE40_RS21180 PAS domain-containing protein low > 107
Sinorhizobium meliloti 1021 0.49 SMc03795 isopropylmalate isomerase small subunit 0.13 SMc04327 hypothetical protein low > 103

Not shown: 53 genomes with orthologs for CSW01_12610 only; 2 genomes with orthologs for CSW01_01875 only