Conservation of cofitness between BWI76_RS21165 and BWI76_RS01555 in Klebsiella michiganensis M5al

59 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS21165 Fe-S cluster assembly transcriptional regulator IscR 1.0 BWI76_RS01555 phosphomethylpyrimidine synthase ThiC 0.33 12
Enterobacter asburiae PDN3 0.86 EX28DRAFT_0108 transcriptional regulator, BadM/Rrf2 family 0.95 EX28DRAFT_4536 phosphomethylpyrimidine synthase low > 76
Enterobacter sp. TBS_079 0.86 MPMX20_03412 HTH-type transcriptional regulator IscR 0.94 MPMX20_00217 Phosphomethylpyrimidine synthase low > 85
Escherichia coli ECOR38 0.84 HEPCGN_20755 iscR Fe-S cluster assembly transcriptional regulator IscR 0.93 HEPCGN_12010 thiC phosphomethylpyrimidine synthase ThiC 0.60 44
Escherichia coli BW25113 0.84 b2531 iscR DNA-binding transcriptional repressor (NCBI) 0.93 b3994 thiC thiamine biosynthesis protein ThiC (NCBI) low > 76
Escherichia coli ECRC99 0.84 KEDOAH_06605 iscR Fe-S cluster assembly transcriptional regulator IscR 0.93 KEDOAH_14785 thiC phosphomethylpyrimidine synthase ThiC — —
Escherichia coli ECRC98 0.84 JDDGAC_25290 iscR Fe-S cluster assembly transcriptional regulator IscR 0.93 JDDGAC_17000 thiC phosphomethylpyrimidine synthase ThiC low > 86
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.84 GFF2436 Iron-sulfur cluster regulator IscR 0.93 GFF4198 Thiamin biosynthesis protein ThiC low > 78
Escherichia coli ECRC102 0.84 NIAGMN_19385 iscR Fe-S cluster assembly transcriptional regulator IscR 0.93 NIAGMN_11125 thiC phosphomethylpyrimidine synthase ThiC — —
Escherichia coli ECRC62 0.84 BNILDI_12085 iscR Fe-S cluster assembly transcriptional regulator IscR 0.93 BNILDI_06005 thiC phosphomethylpyrimidine synthase ThiC low > 75
Escherichia coli Nissle 1917 0.84 ECOLIN_RS14370 Fe-S cluster assembly transcriptional regulator IscR 0.93 ECOLIN_RS23040 phosphomethylpyrimidine synthase ThiC low > 55
Escherichia fergusonii Becca 0.84 EFB2_01359 HTH-type transcriptional regulator IscR 0.93 EFB2_04617 Phosphomethylpyrimidine synthase low > 86
Escherichia coli BL21 0.84 ECD_02423 isc operon transcriptional repressor; suf operon transcriptional activator; oxidative stress- and iron starvation-inducible; autorepressor 0.93 ECD_03871 phosphomethylpyrimidine synthase low > 61
Escherichia coli ECRC101 0.84 MCAODC_12145 iscR Fe-S cluster assembly transcriptional regulator IscR 0.93 MCAODC_03875 thiC phosphomethylpyrimidine synthase ThiC low > 87
Escherichia coli ECRC100 0.84 OKFHMN_21615 iscR Fe-S cluster assembly transcriptional regulator IscR 0.93 OKFHMN_13375 thiC phosphomethylpyrimidine synthase ThiC low > 80
Escherichia coli ECOR27 0.84 NOLOHH_13285 iscR Fe-S cluster assembly transcriptional regulator IscR 0.93 NOLOHH_05520 thiC phosphomethylpyrimidine synthase ThiC 0.57 68
Escherichia coli HS(pFamp)R (ATCC 700891) 0.84 OHPLBJKB_01178 HTH-type transcriptional regulator IscR 0.93 OHPLBJKB_04056 Phosphomethylpyrimidine synthase low > 73
Serratia liquefaciens MT49 0.81 IAI46_19360 Fe-S cluster assembly transcriptional regulator IscR 0.85 IAI46_01320 phosphomethylpyrimidine synthase ThiC low > 86
Erwinia tracheiphila SCR3 0.80 LU632_RS17875 iscR Fe-S cluster assembly transcriptional regulator IscR 0.82 LU632_RS00970 thiC phosphomethylpyrimidine synthase ThiC low > 74
Rahnella sp. WP5 0.80 EX31_RS20550 Fe-S cluster assembly transcriptional regulator IscR 0.86 EX31_RS16815 phosphomethylpyrimidine synthase ThiC low > 89
Pectobacterium carotovorum WPP14 0.79 HER17_RS06010 Fe-S cluster assembly transcriptional regulator IscR 0.86 HER17_RS20380 phosphomethylpyrimidine synthase ThiC low > 75
Dickeya dadantii 3937 0.79 DDA3937_RS15550 Fe-S cluster assembly transcriptional regulator IscR 0.85 DDA3937_RS01175 phosphomethylpyrimidine synthase ThiC — —
Pantoea sp. MT58 0.77 IAI47_05000 Fe-S cluster assembly transcriptional regulator IscR 0.83 IAI47_18085 phosphomethylpyrimidine synthase ThiC low > 76
Dickeya dianthicola 67-19 0.77 HGI48_RS15650 Fe-S cluster assembly transcriptional regulator IscR 0.84 HGI48_RS01170 phosphomethylpyrimidine synthase ThiC — —
Dickeya dianthicola ME23 0.77 DZA65_RS16725 Fe-S cluster assembly transcriptional regulator IscR 0.85 DZA65_RS01215 phosphomethylpyrimidine synthase ThiC low > 75
Alteromonas macleodii MIT1002 0.70 MIT1002_02802 HTH-type transcriptional regulator IscR 0.75 MIT1002_00097 Phosphomethylpyrimidine synthase low > 70
Shewanella loihica PV-4 0.63 Shew_2318 BadM/Rrf2 family transcriptional regulator (RefSeq) 0.77 Shew_2096 thiamine biosynthesis protein ThiC (RefSeq) — —
Shewanella amazonensis SB2B 0.63 Sama_1292 Rrf2 family protein (RefSeq) 0.76 Sama_1860 thiamine biosynthesis protein ThiC (RefSeq) low > 62
Shewanella sp. ANA-3 0.62 Shewana3_2281 BadM/Rrf2 family transcriptional regulator (RefSeq) 0.74 Shewana3_1936 thiamine biosynthesis protein ThiC (RefSeq) low > 73
Shewanella oneidensis MR-1 0.62 SO2263 Rrf2 family protein (NCBI ptt file) 0.74 SO2445 thiC thiamin biosynthesis protein ThiC (NCBI ptt file) low > 76
Pseudomonas syringae pv. syringae B728a 0.60 Psyr_1236 transcriptional regulator, BadM/Rrf2 family 0.70 Psyr_0544 hydroxymethylpyrimidine synthase low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.60 Psyr_1236 transcriptional regulator, BadM/Rrf2 family 0.70 Psyr_0544 hydroxymethylpyrimidine synthase low > 86
Pseudomonas stutzeri RCH2 0.60 Psest_1250 iron-sulfur cluster assembly transcription factor IscR 0.70 Psest_0477 thiamine biosynthesis protein ThiC — —
Pseudomonas sp. S08-1 0.60 OH686_17470 iron-sulfur cluster assembly transcription factor IscR 0.71 OH686_15885 phosphomethylpyrimidine synthase low > 80
Pseudomonas fluorescens FW300-N2C3 0.59 AO356_06650 transcriptional regulator 0.70 AO356_08810 thiamine biosynthesis protein ThiC low > 104
Pseudomonas fluorescens FW300-N2E3 0.59 AO353_15830 transcriptional regulator 0.70 AO353_13010 thiamine biosynthesis protein ThiC low > 101
Pseudomonas simiae WCS417 0.59 PS417_23205 transcriptional regulator 0.70 PS417_02355 thiamine biosynthesis protein ThiC low > 88
Pseudomonas fluorescens SBW25 0.59 PFLU_RS24860 Fe-S cluster assembly transcriptional regulator IscR 0.70 PFLU_RS02430 phosphomethylpyrimidine synthase ThiC low > 109
Pseudomonas putida KT2440 0.59 PP_0841 DNA-binding transcriptional dual regulator 2Fe-2S cluster IscR 0.71 PP_4922 Phosphomethylpyrimidine synthase 0.13 48
Pseudomonas sp. RS175 0.59 PFR28_00285 HTH-type transcriptional regulator IscR 0.71 PFR28_05091 Phosphomethylpyrimidine synthase low > 88
Pseudomonas fluorescens SBW25-INTG 0.59 PFLU_RS24860 Fe-S cluster assembly transcriptional regulator IscR 0.70 PFLU_RS02430 phosphomethylpyrimidine synthase ThiC low > 109
Pseudomonas fluorescens FW300-N1B4 0.53 Pf1N1B4_866 Iron-sulfur cluster regulator IscR 0.70 Pf1N1B4_1447 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) low > 87
Kangiella aquimarina DSM 16071 0.53 B158DRAFT_1458 transcriptional regulator, BadM/Rrf2 family 0.67 B158DRAFT_0295 hydroxymethylpyrimidine synthase 0.63 10
Pseudomonas fluorescens GW456-L13 0.53 PfGW456L13_4874 Iron-sulfur cluster regulator IscR 0.70 PfGW456L13_187 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) low > 87
Marinobacter adhaerens HP15 0.50 HP15_1487 transcriptional regulator, BadM/Rrf2 family 0.69 HP15_453 thiamine biosynthesis protein thiC low > 73
Acinetobacter radioresistens SK82 0.49 MPMX26_01328 HTH-type transcriptional regulator IscR 0.68 MPMX26_00180 Phosphomethylpyrimidine synthase low > 36
Herbaspirillum seropedicae SmR1 0.49 HSERO_RS15775 DNA-binding protein 0.69 HSERO_RS02120 phosphomethylpyrimidine synthase ThiC — —
Castellaniella sp019104865 MT123 0.48 ABCV34_RS05100 Fe-S cluster assembly transcriptional regulator IscR 0.68 ABCV34_RS10825 phosphomethylpyrimidine synthase ThiC low > 48
Dechlorosoma suillum PS 0.47 Dsui_2369 iron-sulfur cluster assembly transcription factor IscR 0.68 Dsui_0422 thiamine biosynthesis protein ThiC — —
Rhodospirillum rubrum S1H 0.45 Rru_A2028 Transcriptional Regulator, BadM/Rrf2 family (NCBI) 0.58 Rru_A2008 Thiamine biosynthesis protein ThiC (NCBI) — —
Azospirillum sp. SherDot2 0.44 MPMX19_01654 HTH-type transcriptional regulator IscR 0.62 MPMX19_00336 Phosphomethylpyrimidine synthase low > 112
Azospirillum brasilense Sp245 0.44 AZOBR_RS05830 Rrf2 family transcriptional regulator 0.64 AZOBR_RS07940 phosphomethylpyrimidine synthase low > 97
Magnetospirillum magneticum AMB-1 0.44 AMB_RS15265 Rrf2 family transcriptional regulator 0.65 AMB_RS01125 phosphomethylpyrimidine synthase — —
Brevundimonas sp. GW460-12-10-14-LB2 0.42 A4249_RS04565 Rrf2 family transcriptional regulator 0.61 A4249_RS15715 phosphomethylpyrimidine synthase ThiC low > 48
Caulobacter crescentus NA1000 Δfur 0.40 CCNA_01942 Rrf2 family protein 0.63 CCNA_02109 thiamine biosynthesis protein thiC low > 67
Caulobacter crescentus NA1000 0.40 CCNA_01942 Rrf2 family protein 0.63 CCNA_02109 thiamine biosynthesis protein thiC low > 66
Dinoroseobacter shibae DFL-12 0.36 Dshi_1633 transcriptional regulator, BadM/Rrf2 family (RefSeq) 0.63 Dshi_4080 thiamine biosynthesis protein ThiC (RefSeq) — —
Phaeobacter inhibens DSM 17395 0.35 PGA1_c15350 putative transcriptional regulator 0.63 PGA1_c09110 thiamine biosynthesis protein ThiC — —
Mycobacterium tuberculosis H37Rv 0.20 Rv1287 Conserved hypothetical protein 0.50 Rv0423c Probable thiamine biosynthesis protein ThiC — —
Pedobacter sp. GW460-11-11-14-LB5 0.18 CA265_RS04090 transcriptional regulator 0.68 CA265_RS20165 phosphomethylpyrimidine synthase ThiC — —

Not shown: 3 genomes with orthologs for BWI76_RS21165 only; 34 genomes with orthologs for BWI76_RS01555 only