| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Agrobacterium fabrum C58 | 1.0 | Atu3181 | | hypothetical protein | 1.0 | Atu2569 | | thiamine biosynthesis protein | 0.24 | 6 |
| Rhodopseudomonas palustris CGA009 | 0.71 | TX73_007510 | | GTP-binding protein | 0.70 | TX73_018540 | | phosphomethylpyrimidine synthase ThiC | low | > 86 |
| Xanthobacter sp. DMC5 | 0.68 | GFF1508 | | Putative metal chaperone YciC | 0.70 | GFF257 | | Phosphomethylpyrimidine synthase | — | — |
| Bosea sp. OAE506 | 0.68 | ABIE41_RS15395 | | GTP-binding protein | 0.71 | ABIE41_RS02770 | | phosphomethylpyrimidine synthase ThiC | low | > 77 |
| Dinoroseobacter shibae DFL-12 | 0.60 | Dshi_2487 | | cobalamin synthesis protein P47K (RefSeq) | 0.85 | Dshi_4080 | | thiamine biosynthesis protein ThiC (RefSeq) | — | — |
| Herbaspirillum seropedicae SmR1 | 0.59 | HSERO_RS12720 | | hypothetical protein | 0.67 | HSERO_RS02120 | | phosphomethylpyrimidine synthase ThiC | low | > 78 |
| Variovorax sp. SCN45 | 0.59 | GFF7058 | | Zinc-binding GTPase YciC | 0.66 | GFF2000 | | Phosphomethylpyrimidine synthase ThiC (EC 4.1.99.17) | low | > 127 |
| Phaeobacter inhibens DSM 17395 | 0.59 | PGA1_c20610 | | putative metal chaperone | 0.81 | PGA1_c09110 | | thiamine biosynthesis protein ThiC | low | > 62 |
| Methylophilus sp. DMC18 | 0.57 | GFF601 | | Putative metal chaperone YciC | 0.69 | GFF2191 | | Phosphomethylpyrimidine synthase | low | > 43 |
| Pectobacterium carotovorum WPP14 | 0.56 | HER17_RS10375 | | zinc metallochaperone GTPase ZigA | 0.67 | HER17_RS20380 | | phosphomethylpyrimidine synthase ThiC | low | > 75 |
| Acinetobacter baumannii LAC-4 | 0.56 | RR41_RS00360 | | zinc metallochaperone GTPase ZigA | 0.66 | RR41_RS17715 | | phosphomethylpyrimidine synthase ThiC | low | > 55 |
| Pantoea agglomerans CFBP13505 P0401 | 0.55 | PagCFBP13505_RS07270 | | GTP-binding protein | 0.66 | PagCFBP13505_RS22620 | | phosphomethylpyrimidine synthase ThiC | low | > 74 |
| Pantoea sp. MT58 | 0.54 | IAI47_21320 | | GTP-binding protein | 0.67 | IAI47_18085 | | phosphomethylpyrimidine synthase ThiC | low | > 76 |
| Pseudomonas fluorescens FW300-N2C3 | 0.54 | AO356_11940 | | 4-hydroxytetrahydrobiopterin dehydratase | 0.67 | AO356_08810 | | thiamine biosynthesis protein ThiC | low | > 104 |
| Pseudomonas fluorescens FW300-N2E2 | 0.54 | Pf6N2E2_4263 | | Putative metal chaperone, involved in Zn homeostasis, GTPase of COG0523 family | 0.67 | Pf6N2E2_3644 | | Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) | low | > 103 |
| Pseudomonas sp. RS175 | 0.54 | PFR28_04533 | | Putative metal chaperone YciC | 0.67 | PFR28_05091 | | Phosphomethylpyrimidine synthase | low | > 88 |
| Pseudomonas sp. DMC3 | 0.54 | GFF522 | | Putative metal chaperone YciC | 0.67 | GFF3183 | | Phosphomethylpyrimidine synthase | low | > 89 |
| Pseudomonas fluorescens SBW25 | 0.53 | PFLU_RS29950 | | GTP-binding protein | 0.67 | PFLU_RS02430 | | phosphomethylpyrimidine synthase ThiC | low | > 109 |
| Pseudomonas simiae WCS417 | 0.53 | PS417_28285 | | hypothetical protein | 0.67 | PS417_02355 | | thiamine biosynthesis protein ThiC | low | > 88 |
| Pseudomonas fluorescens SBW25-INTG | 0.53 | PFLU_RS29950 | | GTP-binding protein | 0.67 | PFLU_RS02430 | | phosphomethylpyrimidine synthase ThiC | low | > 109 |
| Alteromonas macleodii MIT1002 | 0.53 | MIT1002_02552 | | Putative metal chaperone YciC | 0.66 | MIT1002_00097 | | Phosphomethylpyrimidine synthase | low | > 70 |
| Pseudomonas lactucae CFBP13502 | 0.53 | GEMAOFIL_00125 | | Putative metal chaperone YciC | 0.67 | GEMAOFIL_00708 | | Phosphomethylpyrimidine synthase | low | > 96 |
| Pseudomonas fluorescens FW300-N1B4 | 0.53 | Pf1N1B4_1994 | | Putative metal chaperone, involved in Zn homeostasis, GTPase of COG0523 family | 0.67 | Pf1N1B4_1447 | | Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) | low | > 87 |
| Pseudomonas sp. S08-1 | 0.53 | OH686_23515 | | Zinc-binding GTPase YciC | 0.68 | OH686_15885 | | phosphomethylpyrimidine synthase | low | > 80 |
| Pseudomonas fluorescens GW456-L13 | 0.53 | PfGW456L13_713 | | Putative metal chaperone, involved in Zn homeostasis, GTPase of COG0523 family | 0.66 | PfGW456L13_187 | | Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) | low | > 87 |
| Pseudomonas segetis P6 | 0.53 | MPMX49_00203 | | Putative metal chaperone YciC | 0.67 | MPMX49_04184 | | Phosphomethylpyrimidine synthase | low | > 75 |
| Pseudomonas sp. SVBP6 | 0.53 | COO64_RS01890 | zigA | zinc metallochaperone GTPase ZigA | 0.67 | COO64_RS17755 | thiC | phosphomethylpyrimidine synthase ThiC | low | > 93 |
| Pseudomonas stutzeri RCH2 | 0.53 | Psest_0747 | | Putative GTPases (G3E family) | 0.67 | Psest_0477 | | thiamine biosynthesis protein ThiC | low | > 67 |
| Pseudomonas fluorescens FW300-N2E3 | 0.52 | AO353_10110 | | 4-hydroxytetrahydrobiopterin dehydratase | 0.66 | AO353_13010 | | thiamine biosynthesis protein ThiC | low | > 101 |
| Pseudomonas syringae pv. syringae B728a | 0.52 | Psyr_5075 | | Cobalamin synthesis protein/P47K:Cobalamin synthesis protein/P47K | 0.67 | Psyr_0544 | | hydroxymethylpyrimidine synthase | low | > 86 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.52 | Psyr_5075 | | Cobalamin synthesis protein/P47K:Cobalamin synthesis protein/P47K | 0.67 | Psyr_0544 | | hydroxymethylpyrimidine synthase | low | > 86 |
| Pseudomonas aeruginosa PUPa3 | 0.52 | DQ20_RS58405 | zigA;inference=COORDINATES | zinc metallochaperone GTPase ZigA | 0.67 | DQ20_RS51400 | thiC;go_function=iron-sulfur | phosphomethylpyrimidine synthase ThiC | low | > 101 |
| Pseudomonas aeruginosa MRSN321 | 0.52 | DY961_RS25980 | zigA;inference=COORDINATES | zinc metallochaperone GTPase ZigA | 0.67 | DY961_RS10660 | thiC;go_function=iron-sulfur | phosphomethylpyrimidine synthase ThiC | low | > 100 |
| Pseudomonas putida KT2440 | 0.52 | PP_5361 | | 47 kDa protein | 0.68 | PP_4922 | | Phosphomethylpyrimidine synthase | low | > 96 |
| Pseudomonas aeruginosa PA14 | 0.52 | IKLFDK_25735 | | zinc metallochaperone GTPase ZigA | 0.67 | IKLFDK_28675 | | phosphomethylpyrimidine synthase ThiC | low | > 98 |
| Pseudomonas sp. BP01 | 0.52 | JOY50_RS08690 | zigA | zinc metallochaperone GTPase ZigA | 0.67 | JOY50_RS10065 | thiC | phosphomethylpyrimidine synthase ThiC | low | > 84 |
| Rahnella sp. WP5 | 0.52 | EX31_RS15695 | | GTP-binding protein | 0.67 | EX31_RS16815 | | phosphomethylpyrimidine synthase ThiC | low | > 89 |
| Serratia liquefaciens MT49 | 0.51 | IAI46_13510 | | GTP-binding protein | 0.66 | IAI46_01320 | | phosphomethylpyrimidine synthase ThiC | low | > 87 |
| Ralstonia sp. UNC404CL21Col | 0.51 | ABZR87_RS05105 | | zinc metallochaperone GTPase ZigA | 0.64 | ABZR87_RS04785 | | phosphomethylpyrimidine synthase ThiC | 0.59 | 15 |
| Cupriavidus basilensis FW507-4G11 | 0.50 | RR42_RS01025 | | GTPase | 0.63 | RR42_RS01290 | | thiamine biosynthesis protein ThiC | low | > 128 |
| Ralstonia solanacearum IBSBF1503 | 0.50 | RALBFv3_RS09640 | | GTP-binding protein | 0.63 | RALBFv3_RS09940 | | phosphomethylpyrimidine synthase ThiC | low | > 76 |
| Ralstonia solanacearum UW163 | 0.50 | UW163_RS03940 | | GTP-binding protein | 0.63 | UW163_RS03640 | | phosphomethylpyrimidine synthase ThiC | — | — |
| Ralstonia solanacearum GMI1000 | 0.50 | RS_RS00225 | | GTP-binding protein | 0.63 | RS_RS00555 | | phosphomethylpyrimidine synthase | low | > 80 |
| Xanthomonas campestris pv. campestris strain 8004 | 0.50 | Xcc-8004.333.1 | | Putative metal chaperone, involved in Zn homeostasis, GTPase of COG0523 family | 0.64 | Xcc-8004.1066.1 | | hypothetical protein | low | > 74 |
| Ralstonia solanacearum PSI07 | 0.50 | RPSI07_RS23725 | | GTP-binding protein | 0.64 | RPSI07_RS23420 | | phosphomethylpyrimidine synthase ThiC | low | > 81 |
| Burkholderia phytofirmans PsJN | 0.50 | BPHYT_RS19585 | | cobalamin biosynthesis protein CobW | 0.66 | BPHYT_RS13220 | | phosphomethylpyrimidine synthase | low | > 109 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.49 | H281DRAFT_02358 | | GTPase, G3E family | 0.65 | H281DRAFT_00395 | | hydroxymethylpyrimidine synthase | low | > 103 |
| Dickeya dadantii 3937 | 0.49 | DDA3937_RS12435 | | GTP-binding protein | 0.66 | DDA3937_RS01175 | | phosphomethylpyrimidine synthase ThiC | low | > 74 |
| Echinicola vietnamensis KMM 6221, DSM 17526 | 0.49 | Echvi_2702 | | Putative GTPases (G3E family) | 0.68 | Echvi_3567 | | thiamine biosynthesis protein ThiC | low | > 79 |
| Paraburkholderia graminis OAS925 | 0.45 | ABIE53_000293 | | G3E family GTPase | 0.66 | ABIE53_002857 | | phosphomethylpyrimidine synthase | low | > 113 |
| Paraburkholderia sabiae LMG 24235 | 0.36 | QEN71_RS29500 | | GTP-binding protein | 0.66 | QEN71_RS05480 | | phosphomethylpyrimidine synthase ThiC | low | > 153 |
| Phocaeicola vulgatus CL09T03C04 | 0.30 | HMPREF1058_RS13270 | | GTP-binding protein | 0.58 | HMPREF1058_RS03280 | | phosphomethylpyrimidine synthase ThiC | low | > 67 |
| Phocaeicola dorei CL03T12C01 | 0.30 | ABI39_RS08435 | | GTP-binding protein | 0.58 | ABI39_RS17760 | | phosphomethylpyrimidine synthase ThiC | low | > 72 |
| Bacteroides stercoris CC31F | 0.24 | HMPREF1181_RS07845 | | GTP-binding protein | 0.57 | HMPREF1181_RS14685 | | phosphomethylpyrimidine synthase ThiC | low | > 56 |
| Escherichia coli Nissle 1917 | 0.15 | ECOLIN_RS05820 | | GTP-binding protein | 0.67 | ECOLIN_RS23040 | | phosphomethylpyrimidine synthase ThiC | — | — |
| Escherichia fergusonii Becca | 0.15 | EFB2_02962 | | Putative metal chaperone YciC | 0.67 | EFB2_04617 | | Phosphomethylpyrimidine synthase | low | > 86 |
| Mycobacterium tuberculosis H37Rv | 0.11 | Rv0106 | | Conserved hypothetical protein | 0.54 | Rv0423c | | Probable thiamine biosynthesis protein ThiC | — | — |
Not shown: 2 genomes with orthologs for Atu3181 only; 54 genomes with orthologs for Atu2569 only