Conservation of cofitness between ABZR87_RS11225 and ABZR87_RS10950 in Ralstonia sp. UNC404CL21Col

60 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Ralstonia sp. UNC404CL21Col 1.0 ABZR87_RS11225 DHA2 family efflux MFS transporter permease subunit 1.0 ABZR87_RS10950 FtsH protease activity modulator HflK 0.45 9
Ralstonia solanacearum IBSBF1503 0.94 RALBFv3_RS15695 MFS transporter 0.90 RALBFv3_RS15310 FtsH protease activity modulator HflK low > 76
Ralstonia solanacearum GMI1000 0.92 RS_RS06475 MFS transporter 0.87 RS_RS06120 FtsH protease activity modulator HflK low > 80
Ralstonia solanacearum PSI07 0.92 RPSI07_RS17660 MFS transporter 0.90 RPSI07_RS18065 FtsH protease activity modulator HflK low > 81
Cupriavidus basilensis FW507-4G11 0.80 RR42_RS12830 multidrug resistance protein B 0.65 RR42_RS13105 membrane protein — —
Paraburkholderia bryophila 376MFSha3.1 0.69 H281DRAFT_05107 MFS transporter, DHA2 family, multidrug resistance protein 0.42 H281DRAFT_00523 protease FtsH subunit HflK low > 103
Paraburkholderia sabiae LMG 24235 0.69 QEN71_RS23085 DHA2 family efflux MFS transporter permease subunit 0.44 QEN71_RS06010 FtsH protease activity modulator HflK 0.40 30
Paraburkholderia graminis OAS925 0.69 ABIE53_002458 DHA2 family multidrug resistance protein 0.42 ABIE53_002735 membrane protease subunit HflK low > 113
Burkholderia phytofirmans PsJN 0.67 BPHYT_RS08085 DSBA oxidoreductase 0.41 BPHYT_RS12545 membrane protein — —
Variovorax sp. SCN45 0.66 GFF4771 Multidrug efflux system EmrAB-OMF, inner-membrane proton/drug antiporter EmrB (MFS type) 0.42 GFF1002 HflK protein low > 127
Hydrogenophaga sp. GW460-11-11-14-LB1 0.64 GFF3757 Inner membrane component of tripartite multidrug resistance system 0.42 GFF4856 HflK protein low > 90
Variovorax sp. OAS795 0.64 ABID97_RS20390 DHA2 family efflux MFS transporter permease subunit 0.41 ABID97_RS14260 FtsH protease activity modulator HflK low > 91
Herbaspirillum seropedicae SmR1 0.64 HSERO_RS13575 DSBA oxidoreductase 0.46 HSERO_RS14765 membrane protein low > 78
Acidovorax sp. GW101-3H11 0.61 Ac3H11_2352 Inner membrane component of tripartite multidrug resistance system 0.41 Ac3H11_1801 HflK protein low > 79
Castellaniella sp019104865 MT123 0.59 ABCV34_RS05950 DHA2 family efflux MFS transporter permease subunit 0.38 ABCV34_RS02660 FtsH protease activity modulator HflK — —
Enterobacter sp. TBS_079 0.56 MPMX20_03564 Multidrug export protein EmrB 0.24 MPMX20_00455 Modulator of FtsH protease HflK low > 85
Enterobacter asburiae PDN3 0.56 EX28DRAFT_2769 drug resistance transporter, EmrB/QacA subfamily 0.24 EX28DRAFT_3371 HflK protein low > 76
Rhodospirillum rubrum S1H 0.56 Rru_A0858 Drug resistance transporter EmrB/QacA subfamily (NCBI) 0.23 Rru_A2203 HflK (NCBI) — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.55 GFF1593 Multidrug resistance protein B 0.24 GFF827 HflK protein low > 78
Rahnella sp. WP5 0.55 EX31_RS13660 multidrug efflux MFS transporter permease subunit EmrB 0.23 EX31_RS08810 FtsH protease activity modulator HflK low > 89
Dickeya dianthicola ME23 0.55 DZA65_RS17910 multidrug efflux MFS transporter permease subunit EmrB 0.25 DZA65_RS19670 FtsH protease activity modulator HflK low > 75
Klebsiella michiganensis M5al 0.55 BWI76_RS22100 multidrug effux MFS transporter subunit EmrB 0.24 BWI76_RS02545 protease modulator HflK low > 92
Dickeya dianthicola 67-19 0.55 HGI48_RS16835 multidrug efflux MFS transporter permease subunit EmrB 0.25 HGI48_RS18535 FtsH protease activity modulator HflK low > 71
Pectobacterium carotovorum WPP14 0.55 HER17_RS04460 multidrug efflux MFS transporter permease subunit EmrB 0.24 HER17_RS02595 FtsH protease activity modulator HflK low > 75
Escherichia coli Nissle 1917 0.54 ECOLIN_RS14970 multidrug efflux MFS transporter permease subunit EmrB 0.24 ECOLIN_RS24240 FtsH protease activity modulator HflK low > 55
Escherichia coli ECOR38 0.54 HEPCGN_19970 emrB multidrug efflux MFS transporter permease subunit EmrB 0.24 HEPCGN_10475 hflK FtsH protease activity modulator HflK low > 87
Dickeya dadantii 3937 0.54 DDA3937_RS16765 multidrug efflux MFS transporter permease subunit EmrB 0.25 DDA3937_RS18600 FtsH protease activity modulator HflK low > 74
Escherichia coli HS(pFamp)R (ATCC 700891) 0.54 OHPLBJKB_01047 Multidrug export protein EmrB 0.24 OHPLBJKB_03868 Modulator of FtsH protease HflK low > 73
Escherichia coli BW25113 0.54 b2686 emrB multidrug efflux system protein (NCBI) 0.24 b4174 hflK modulator for HflB protease specific for phage lambda cII repressor (NCBI) low > 76
Escherichia coli BL21 0.54 ECD_02541 multidrug efflux system protein 0.24 ECD_04041 modulator for HflB protease specific for phage lambda cII repressor low > 61
Escherichia coli ECRC101 0.54 MCAODC_11300 emrB multidrug efflux MFS transporter permease subunit EmrB 0.24 MCAODC_02760 hflK FtsH protease activity modulator HflK low > 87
Escherichia coli ECRC99 0.54 KEDOAH_07360 emrB multidrug efflux MFS transporter permease subunit EmrB 0.24 KEDOAH_15910 hflK FtsH protease activity modulator HflK — —
Escherichia coli ECRC100 0.54 OKFHMN_20775 emrB multidrug efflux MFS transporter permease subunit EmrB 0.24 OKFHMN_12245 hflK FtsH protease activity modulator HflK 0.76 61
Escherichia coli ECRC98 0.54 JDDGAC_24440 emrB multidrug efflux MFS transporter permease subunit EmrB 0.24 JDDGAC_15885 hflK FtsH protease activity modulator HflK low > 86
Escherichia coli ECRC62 0.54 BNILDI_11175 emrB multidrug efflux MFS transporter permease subunit EmrB 0.24 BNILDI_06980 hflK FtsH protease activity modulator HflK low > 75
Escherichia coli ECRC102 0.54 NIAGMN_18545 emrB multidrug efflux MFS transporter permease subunit EmrB 0.24 NIAGMN_10095 hflK FtsH protease activity modulator HflK — —
Escherichia coli ECOR27 0.54 NOLOHH_12615 emrB multidrug efflux MFS transporter permease subunit EmrB 0.24 NOLOHH_04510 hflK FtsH protease activity modulator HflK low > 75
Escherichia fergusonii Becca 0.54 EFB2_01242 Multidrug export protein EmrB 0.24 EFB2_04361 Modulator of FtsH protease HflK low > 86
Pantoea sp. MT58 0.54 IAI47_04495 multidrug efflux MFS transporter permease subunit EmrB 0.26 IAI47_02600 FtsH protease activity modulator HflK 0.36 36
Serratia liquefaciens MT49 0.53 IAI46_20005 multidrug efflux MFS transporter permease subunit EmrB 0.24 IAI46_01635 FtsH protease activity modulator HflK low > 86
Pseudomonas fluorescens GW456-L13 0.46 PfGW456L13_2606 Inner membrane component of tripartite multidrug resistance system 0.25 PfGW456L13_152 HflK protein low > 87
Pseudomonas putida KT2440 0.46 PP_3548 multidrug efflux transport system - permease subunit 0.27 PP_4892 integral membrane ATP-dependent zinc metallopeptidase / HflK-HflC complex low > 96
Pseudomonas fluorescens FW300-N2C3 0.46 AO356_01025 multidrug resistance protein B 0.26 AO356_08645 hypothetical protein low > 104
Pseudomonas sp. RS175 0.46 PFR28_02747 Multidrug export protein EmrB 0.27 PFR28_05123 Modulator of FtsH protease HflK low > 88
Pseudomonas fluorescens FW300-N1B4 0.46 Pf1N1B4_4002 Inner membrane component of tripartite multidrug resistance system 0.27 Pf1N1B4_1410 HflK protein — —
Pseudomonas fluorescens SBW25 0.45 PFLU_RS18895 DHA2 family efflux MFS transporter permease subunit 0.27 PFLU_RS02580 FtsH protease activity modulator HflK low > 109
Pseudomonas fluorescens SBW25-INTG 0.45 PFLU_RS18895 DHA2 family efflux MFS transporter permease subunit 0.27 PFLU_RS02580 FtsH protease activity modulator HflK low > 109
Pseudomonas fluorescens FW300-N2E3 0.45 AO353_27840 multidrug resistance protein B 0.27 AO353_13155 hypothetical protein low > 101
Pseudomonas simiae WCS417 0.45 PS417_16910 multidrug resistance protein B 0.27 PS417_02500 membrane protein — —
Pseudomonas fluorescens FW300-N2E2 0.45 Pf6N2E2_149 Inner membrane component of tripartite multidrug resistance system 0.26 Pf6N2E2_3612 HflK protein low > 103
Pseudomonas syringae pv. syringae B728a ΔmexB 0.44 Psyr_1731 Drug resistance transporter EmrB/QacA subfamily 0.26 Psyr_0574 protease FtsH subunit HflK low > 86
Pseudomonas syringae pv. syringae B728a 0.44 Psyr_1731 Drug resistance transporter EmrB/QacA subfamily 0.26 Psyr_0574 protease FtsH subunit HflK low > 86
Vibrio cholerae E7946 ATCC 55056 0.42 CSW01_07075 MFS transporter 0.28 CSW01_01845 protease modulator HflK low > 62
Azospirillum sp. SherDot2 0.30 MPMX19_05353 Fatty acid resistance protein FarB 0.23 MPMX19_01251 Modulator of FtsH protease HflK — —
Erwinia tracheiphila SCR3 0.30 LU632_RS09490 DHA2 family efflux MFS transporter permease subunit 0.25 LU632_RS02065 hflK FtsH protease activity modulator HflK low > 74
Rhizobium sp. OAE497 0.29 ABIE40_RS21925 DHA2 family efflux MFS transporter permease subunit 0.22 ABIE40_RS11535 FtsH protease activity modulator HflK low > 107
Shewanella loihica PV-4 0.24 Shew_3405 EmrB/QacA family drug resistance transporter (RefSeq) 0.25 Shew_0568 HflK protein (RefSeq) 0.30 40
Shewanella oneidensis MR-1 0.23 SO0525 drug resistance transporter, EmrB/QacA family protein (NCBI ptt file) 0.25 SO0605 hflK hflK protein (NCBI ptt file) low > 76
Shewanella amazonensis SB2B 0.23 Sama_0403 drug resistance transporter, EmrB/QacA family protein (RefSeq) 0.23 Sama_3023 hflK protein (RefSeq) 0.35 34
Pseudomonas sp. S08-1 0.22 OH686_04570 Inner-membrane proton/drug antiporter (MSF type) of tripartite multidrug efflux system 0.24 OH686_09460 HflK protein low > 80
Ralstonia solanacearum UW163 0.18 UW163_RS07870 MFS transporter 0.90 UW163_RS12775 FtsH protease activity modulator HflK — —

Not shown: 21 genomes with orthologs for ABZR87_RS11225 only; 4 genomes with orthologs for ABZR87_RS10950 only