Conservation of cofitness between HER17_RS02310 and HER17_RS12360 in Pectobacterium carotovorum WPP14

57 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pectobacterium carotovorum WPP14 1.0 HER17_RS02310 methionine synthase 1.0 HER17_RS12360 leucine-responsive transcriptional regulator Lrp 0.57 11
Dickeya dianthicola ME23 0.88 DZA65_RS20250 methionine synthase 1.00 DZA65_RS09915 leucine-responsive transcriptional regulator Lrp low > 75
Rahnella sp. WP5 0.88 EX31_RS11760 methionine synthase 0.99 EX31_RS18530 leucine-responsive transcriptional regulator Lrp 0.73 37
Dickeya dadantii 3937 0.88 DDA3937_RS19040 methionine synthase 1.00 DDA3937_RS09590 leucine-responsive transcriptional regulator Lrp low > 74
Klebsiella michiganensis M5al 0.88 BWI76_RS01685 methionine synthase 0.99 BWI76_RS09655 leucine-responsive regulatory protein 0.42 82
Serratia liquefaciens MT49 0.88 IAI46_23155 methionine synthase 0.98 IAI46_08555 leucine-responsive transcriptional regulator Lrp low > 86
Enterobacter asburiae PDN3 0.87 EX28DRAFT_4326 methionine synthase (B12-dependent) (EC 2.1.1.13) 0.99 EX28DRAFT_2043 transcriptional regulator, AsnC family low > 76
Dickeya dianthicola 67-19 0.87 HGI48_RS19130 methionine synthase 1.00 HGI48_RS09605 leucine-responsive transcriptional regulator Lrp low > 71
Enterobacter sp. TBS_079 0.87 MPMX20_00235 Methionine synthase 0.99 MPMX20_01551 Leucine-responsive regulatory protein low > 85
Escherichia coli BL21 0.87 ECD_03891 homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent 0.98 ECD_00893 leucine-responsive global transcriptional regulator low > 61
Escherichia coli ECRC102 0.87 NIAGMN_10990 metH methionine synthase 0.98 NIAGMN_03295 lrp leucine-responsive transcriptional regulator Lrp
Escherichia coli BW25113 0.87 b4019 metH B12-dependent methionine synthase (NCBI) 0.98 b0889 lrp DNA-binding transcriptional dual regulator, leucine-binding (NCBI) low > 76
Escherichia coli HS(pFamp)R (ATCC 700891) 0.87 OHPLBJKB_04030 Methionine synthase 0.98 OHPLBJKB_02779 Leucine-responsive regulatory protein low > 73
Escherichia coli ECRC99 0.87 KEDOAH_14920 metH methionine synthase 0.98 KEDOAH_22160 lrp leucine-responsive transcriptional regulator Lrp
Escherichia coli ECRC101 0.87 MCAODC_03740 metH methionine synthase 0.98 MCAODC_24965 lrp leucine-responsive transcriptional regulator Lrp 0.57 24
Escherichia coli ECRC100 0.87 OKFHMN_13240 metH methionine synthase 0.98 OKFHMN_05575 lrp leucine-responsive transcriptional regulator Lrp 0.67 56
Escherichia coli ECRC62 0.87 BNILDI_06140 metH methionine synthase 0.98 BNILDI_20400 lrp leucine-responsive transcriptional regulator Lrp low > 75
Escherichia coli ECRC98 0.87 JDDGAC_16865 metH methionine synthase 0.98 JDDGAC_09385 lrp leucine-responsive transcriptional regulator Lrp low > 86
Escherichia coli ECOR38 0.87 HEPCGN_11885 metH methionine synthase 0.98 HEPCGN_22935 lrp leucine-responsive transcriptional regulator Lrp low > 87
Escherichia coli ECOR27 0.87 NOLOHH_05380 metH methionine synthase 0.98 NOLOHH_22145 lrp leucine-responsive transcriptional regulator Lrp low > 75
Escherichia coli Nissle 1917 0.87 ECOLIN_RS23160 methionine synthase 0.98 ECOLIN_RS04730 leucine-responsive transcriptional regulator Lrp low > 55
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.86 GFF1358 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) 0.99 GFF4893 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system low > 78
Escherichia fergusonii Becca 0.86 EFB2_04592 Methionine synthase 0.98 EFB2_03172 Leucine-responsive regulatory protein low > 86
Pantoea sp. MT58 0.86 IAI47_17990 methionine synthase 0.97 IAI47_12915 leucine-responsive transcriptional regulator Lrp 0.45 63
Vibrio cholerae E7946 ATCC 55056 0.76 CSW01_02060 methionine synthase 0.93 CSW01_09530 leucine-responsive transcriptional regulator Lrp
Shewanella amazonensis SB2B 0.66 Sama_0758 metH B12-dependent methionine synthase (RefSeq) 0.82 Sama_1771 leucine-responsive transcriptional regulator (RefSeq) low > 62
Pseudomonas sp. S08-1 0.66 OH686_03335 methionine synthase 0.58 OH686_13680 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system low > 80
Shewanella sp. ANA-3 0.66 Shewana3_3282 metH B12-dependent methionine synthase (RefSeq) 0.80 Shewana3_2049 leucine-responsive transcriptional regulator (RefSeq) low > 73
Pseudomonas simiae WCS417 0.66 PS417_12310 methionine synthase 0.58 PS417_27710 AsnC family transcriptional regulator low > 88
Pseudomonas stutzeri RCH2 0.66 Psest_2102 5-methyltetrahydrofolate--homocysteine methyltransferase 0.57 Psest_3794 Transcriptional regulators low > 67
Pseudomonas sp. RS175 0.66 PFR28_01369 Methionine synthase 0.58 PFR28_04400 Leucine-responsive regulatory protein low > 88
Pseudomonas fluorescens SBW25-INTG 0.66 PFLU_RS13000 methionine synthase 0.58 PFLU_RS29385 AsnC family transcriptional regulator low > 109
Pseudomonas fluorescens SBW25 0.66 PFLU_RS13000 methionine synthase 0.58 PFLU_RS29385 AsnC family transcriptional regulator low > 109
Shewanella oneidensis MR-1 0.66 SO1030 metH 5-methyltetrahydrofolate--homocysteine methyltransferase (NCBI ptt file) 0.80 SO2305 lrp leucine-responsive regulatory protein (NCBI ptt file) low > 76
Pseudomonas fluorescens FW300-N2C3 0.66 AO356_00545 methionine synthase 0.58 AO356_12615 AsnC family transcriptional regulator low > 104
Pseudomonas fluorescens GW456-L13 0.66 PfGW456L13_2847 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) 0.58 PfGW456L13_811 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system low > 87
Pseudomonas putida KT2440 0.65 PP_2375 cobalamin-dependent methionine synthase 0.58 PP_5271 DNA-binding transcriptional dual regulator, leucine-binding low > 96
Pseudomonas fluorescens FW300-N2E2 0.65 Pf6N2E2_2068 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) 0.58 Pf6N2E2_4390 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system low > 103
Pseudomonas fluorescens FW300-N2E3 0.65 AO353_21615 methionine synthase 0.58 AO353_09160 AsnC family transcriptional regulator low > 101
Pseudomonas fluorescens FW300-N1B4 0.65 Pf1N1B4_5661 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) 0.58 Pf1N1B4_2143 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system low > 87
Pseudomonas syringae pv. syringae B728a 0.65 Psyr_2464 methionine synthase (B12-dependent) 0.60 Psyr_0234 transcriptional regulator, AsnC family low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.65 Psyr_2464 methionine synthase (B12-dependent) 0.60 Psyr_0234 transcriptional regulator, AsnC family low > 86
Shewanella loihica PV-4 0.64 Shew_0710 metH B12-dependent methionine synthase (RefSeq) 0.83 Shew_2025 leucine-responsive transcriptional regulator (RefSeq) low > 60
Kangiella aquimarina DSM 16071 0.64 B158DRAFT_2466 methionine synthase (B12-dependent) (EC 2.1.1.13) 0.67 B158DRAFT_1822 Transcriptional regulators low > 40
Marinobacter adhaerens HP15 0.63 HP15_1792 B12-dependent methionine synthase 0.47 HP15_2690 transcriptional regulator, AsnC family low > 73
Acinetobacter radioresistens SK82 0.62 MPMX26_02351 Methionine synthase 0.49 MPMX26_01467 Leucine-responsive regulatory protein low > 36
Dechlorosoma suillum PS 0.61 Dsui_0779 5-methyltetrahydrofolate--homocysteine methyltransferase 0.39 Dsui_3228 transcriptional regulator
Rhodopseudomonas palustris CGA009 0.60 TX73_019180 methionine synthase 0.37 TX73_021105 Lrp/AsnC family transcriptional regulator low > 86
Herbaspirillum seropedicae SmR1 0.60 HSERO_RS21740 methionine synthase 0.58 HSERO_RS00865 AsnC family transcriptional regulator low > 78
Agrobacterium fabrum C58 0.60 Atu2155 methionine synthase 0.45 Atu4159 AsnC family transcriptional regulator low > 89
Mucilaginibacter yixingensis YX-36 DSM 26809 0.60 ABZR88_RS20930 methionine synthase 0.35 ABZR88_RS00795 Lrp/AsnC family transcriptional regulator 0.71 20
Rhizobium sp. OAE497 0.60 ABIE40_RS12135 methionine synthase 0.41 ABIE40_RS23450 Lrp/AsnC family transcriptional regulator low > 107
Sinorhizobium meliloti 1021 0.60 SMc03112 B12-dependent methionine synthase 0.54 SMc00681 leucine-responsive regulatory protein low > 103
Pedobacter sp. GW460-11-11-14-LB5 0.59 CA265_RS23440 methionine synthase 0.34 CA265_RS10900 Lrp/AsnC family transcriptional regulator low > 88
Castellaniella sp019104865 MT123 0.57 ABCV34_RS14560 methionine synthase 0.51 ABCV34_RS10805 winged helix-turn-helix transcriptional regulator low > 48
Magnetospirillum magneticum AMB-1 0.21 AMB_RS02225 methionine synthase 0.36 AMB_RS03420 Lrp/AsnC family transcriptional regulator
Azospirillum sp. SherDot2 0.21 MPMX19_00637 Methionine synthase 0.51 MPMX19_03947 Leucine-responsive regulatory protein
Rhodospirillum rubrum S1H 0.21 Rru_A1531 5-methyltetrahydrofolate--homocysteine methyltransferase (NCBI) 0.51 Rru_A0655 Transcriptional Regulator, AsnC family (NCBI)

Not shown: 5 genomes with orthologs for HER17_RS02310 only; 29 genomes with orthologs for HER17_RS12360 only