Conservation of cofitness between HER17_RS21560 and HER17_RS06320 in Pectobacterium carotovorum WPP14

56 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pectobacterium carotovorum WPP14 1.0 HER17_RS21560 response regulator 1.0 HER17_RS06320 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.58 8
Dickeya dianthicola 67-19 0.82 HGI48_RS21345 response regulator 0.81 HGI48_RS15345 MdtB/MuxB family multidrug efflux RND transporter permease subunit low > 71
Dickeya dianthicola ME23 0.81 DZA65_RS22325 response regulator 0.82 DZA65_RS16165 MdtB/MuxB family multidrug efflux RND transporter permease subunit low > 75
Pantoea sp. MT58 0.79 IAI47_00340 response regulator 0.76 IAI47_06870 MdtB/MuxB family multidrug efflux RND transporter permease subunit low > 76
Rahnella sp. WP5 0.76 EX31_RS03275 response regulator 0.62 EX31_RS13380 MMPL family transporter low > 89
Enterobacter asburiae PDN3 0.74 EX28DRAFT_3057 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain 0.79 EX28DRAFT_0483 Cation/multidrug efflux pump low > 76
Serratia liquefaciens MT49 0.74 IAI46_21235 response regulator 0.81 IAI46_18975 MdtB/MuxB family multidrug efflux RND transporter permease subunit low > 86
Klebsiella michiganensis M5al 0.72 BWI76_RS24335 two-component system response regulator QseB 0.79 BWI76_RS19255 multidrug transporter subunit MdtB low > 92
Enterobacter sp. TBS_079 0.72 MPMX20_03863 Transcriptional regulatory protein QseB 0.79 MPMX20_03061 Multidrug resistance protein MdtB low > 85
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.72 GFF3138 Two-component system response regulator QseB 0.77 GFF3854 Multidrug transporter MdtB low > 78
Escherichia coli ECOR27 0.71 NOLOHH_10660 Transcriptional regulatory protein QseB 0.78 NOLOHH_15540 mdtB multidrug efflux RND transporter permease subunit MdtB low > 75
Escherichia coli ECRC98 0.71 JDDGAC_22515 Transcriptional regulatory protein QseB 0.78 JDDGAC_28305 mdtB multidrug efflux RND transporter permease subunit MdtB low > 86
Escherichia coli ECRC102 0.71 NIAGMN_16645 Transcriptional regulatory protein QseB 0.78 NIAGMN_22140 mdtB multidrug efflux RND transporter permease subunit MdtB — —
Escherichia coli ECRC101 0.71 MCAODC_09395 Transcriptional regulatory protein QseB 0.78 MCAODC_20745 mdtB multidrug efflux RND transporter permease subunit MdtB low > 87
Escherichia coli ECRC99 0.71 KEDOAH_09265 Transcriptional regulatory protein QseB 0.78 KEDOAH_03955 mdtB multidrug efflux RND transporter permease subunit MdtB — —
Escherichia coli ECRC100 0.71 OKFHMN_18880 Transcriptional regulatory protein QseB 0.78 OKFHMN_24195 mdtB multidrug efflux RND transporter permease subunit MdtB low > 80
Escherichia coli ECRC62 0.71 BNILDI_00855 Transcriptional regulatory protein QseB 0.78 BNILDI_14455 mdtB multidrug efflux RND transporter permease subunit MdtB low > 75
Escherichia coli BW25113 0.71 b3025 qseB DNA-binding response regulator in two-component regulatory system with QseC (NCBI) 0.78 b2075 mdtB multidrug efflux system, subunit B (NCBI) 0.19 39
Escherichia fergusonii Becca 0.70 EFB2_00788 Transcriptional regulatory protein QseB 0.78 EFB2_01780 Multidrug resistance protein MdtB low > 86
Escherichia coli BL21 0.70 ECD_02897 quorum sensing DNA-binding response regulator in two-component regulatory system with QseC 0.78 ECD_01980 multidrug efflux system, subunit B low > 61
Escherichia coli ECOR38 0.70 HEPCGN_17740 Quorum sensing DNA-binding response regulator in two-component regulatory system with QseC 0.78 HEPCGN_02885 mdtB multidrug efflux RND transporter permease subunit MdtB low > 87
Escherichia coli Nissle 1917 0.70 ECOLIN_RS17425 quorum sensing response regulator transcription factor QseB 0.78 ECOLIN_RS12200 multidrug efflux RND transporter permease subunit MdtB low > 55
Escherichia coli HS(pFamp)R (ATCC 700891) 0.70 OHPLBJKB_00677 Transcriptional regulatory protein QseB 0.78 OHPLBJKB_01629 Multidrug resistance protein MdtB low > 73
Paraburkholderia graminis OAS925 0.55 ABIE53_003418 two-component system response regulator QseB 0.58 ABIE53_001783 multidrug efflux pump low > 113
Burkholderia phytofirmans PsJN 0.55 BPHYT_RS16220 transcriptional regulator 0.58 BPHYT_RS07785 multidrug transporter — —
Paraburkholderia bryophila 376MFSha3.1 0.54 H281DRAFT_04180 two component transcriptional regulator, winged helix family 0.59 H281DRAFT_06492 multidrug efflux pump low > 103
Paraburkholderia sabiae LMG 24235 0.52 QEN71_RS02475 response regulator 0.60 QEN71_RS23305 MdtB/MuxB family multidrug efflux RND transporter permease subunit low > 153
Hydrogenophaga sp. GW460-11-11-14-LB1 0.52 GFF700 Two-component system response regulator QseB 0.56 GFF487 Cobalt-zinc-cadmium resistance protein CzcA; Cation efflux system protein CusA low > 90
Herbaspirillum seropedicae SmR1 0.51 HSERO_RS21985 transcriptional regulator 0.67 HSERO_RS07650 multidrug transporter low > 78
Pseudomonas sp. S08-1 0.51 OH686_04665 Two-component system response regulator QseB 0.63 OH686_00925 Multidrug efflux system MdtABC-TolC, inner-membrane proton/drug antiporter MdtB (RND type) low > 80
Variovorax sp. SCN45 0.51 GFF1175 Two-component system response regulator QseB 0.56 GFF6659 Multidrug efflux system MdtABC-TolC, inner-membrane proton/drug antiporter MdtB (RND type) low > 127
Variovorax sp. OAS795 0.50 ABID97_RS14955 response regulator 0.54 ABID97_RS20855 efflux RND transporter permease subunit low > 91
Pseudomonas sp. RS175 0.50 PFR28_02328 Transcriptional regulatory protein QseB 0.62 PFR28_02194 Multidrug resistance protein MdtB low > 88
Cupriavidus basilensis FW507-4G11 0.50 RR42_RS37390 XRE family transcriptional regulator 0.63 RR42_RS03310 multidrug transporter low > 128
Pseudomonas simiae WCS417 0.50 PS417_13595 XRE family transcriptional regulator 0.61 PS417_12745 multidrug transporter low > 88
Pseudomonas fluorescens SBW25-INTG 0.49 PFLU_RS15245 response regulator 0.61 PFLU_RS13430 MdtB/MuxB family multidrug efflux RND transporter permease subunit low > 109
Pseudomonas fluorescens SBW25 0.49 PFLU_RS15245 response regulator 0.61 PFLU_RS13430 MdtB/MuxB family multidrug efflux RND transporter permease subunit low > 109
Pseudomonas fluorescens GW456-L13 0.49 PfGW456L13_3169 Two-component system response regulator QseB 0.62 PfGW456L13_3266 Acriflavin resistance plasma membrane protein low > 87
Pseudomonas fluorescens FW300-N2C3 0.49 AO356_23845 XRE family transcriptional regulator 0.62 AO356_25875 multidrug transporter low > 104
Pseudomonas fluorescens FW300-N2E2 0.49 Pf6N2E2_1539 Two-component system response regulator QseB 0.62 Pf6N2E2_1272 Acriflavin resistance plasma membrane protein low > 103
Pseudomonas fluorescens FW300-N1B4 0.49 Pf1N1B4_4454 Two-component system response regulator QseB 0.61 Pf1N1B4_4665 Acriflavin resistance plasma membrane protein — —
Acidovorax sp. GW101-3H11 0.49 Ac3H11_3946 Two-component system response regulator QseB 0.59 Ac3H11_3618 Cobalt-zinc-cadmium resistance protein CzcA; Cation efflux system protein CusA low > 79
Ralstonia sp. UNC404CL21Col 0.48 ABZR87_RS22890 response regulator transcription factor 0.66 ABZR87_RS19025 MdtB/MuxB family multidrug efflux RND transporter permease subunit low > 80
Pseudomonas putida KT2440 0.48 PP_2713 DNA-binding response regulator 0.61 PP_3584 multidrug efflux transport system - membrane subunit low > 96
Pseudomonas stutzeri RCH2 0.48 Psest_3476 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain 0.60 Psest_2139 Cation/multidrug efflux pump low > 67
Ralstonia solanacearum GMI1000 0.48 RS_RS24590 DNA-binding response regulator 0.65 RS_RS22915 multidrug transporter subunit MdtB low > 80
Pseudomonas fluorescens FW300-N2E3 0.47 AO353_19370 transcriptional regulator 0.62 AO353_22895 multidrug transporter low > 101
Ralstonia solanacearum PSI07 0.47 RPSI07_RS07290 DNA-binding response regulator 0.65 RPSI07_RS05515 multidrug transporter subunit MdtB low > 81
Ralstonia solanacearum UW163 0.46 UW163_RS17155 DNA-binding response regulator 0.66 UW163_RS21010 multidrug transporter subunit MdtB — —
Ralstonia solanacearum IBSBF1503 0.46 RALBFv3_RS16415 DNA-binding response regulator 0.66 RALBFv3_RS18120 multidrug transporter subunit MdtB low > 76
Pseudomonas syringae pv. syringae B728a 0.44 Psyr_3511 Response regulator receiver:Transcriptional regulatory protein, C-terminal 0.59 Psyr_2483 Acriflavin resistance protein low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.44 Psyr_3511 Response regulator receiver:Transcriptional regulatory protein, C-terminal 0.59 Psyr_2483 Acriflavin resistance protein low > 86
Acinetobacter radioresistens SK82 0.44 MPMX26_03174 Transcriptional regulatory protein QseB 0.23 MPMX26_02516 Multidrug resistance protein MdtC low > 36
Rhodanobacter denitrificans FW104-10B01 0.44 LRK54_RS14145 response regulator transcription factor 0.49 LRK54_RS09845 efflux RND transporter permease subunit low > 59
Rhodanobacter denitrificans MT42 0.44 LRK55_RS13865 response regulator transcription factor 0.49 LRK55_RS09505 efflux RND transporter permease subunit low > 63
Dyella japonica UNC79MFTsu3.2 0.41 ABZR86_RS20365 response regulator transcription factor 0.49 ABZR86_RS16320 efflux RND transporter permease subunit low > 74
Xanthomonas campestris pv. campestris strain 8004 0.39 Xcc-8004.4942.1 Two-component system regulatory protein 0.48 Xcc-8004.4792.1 Acriflavin resistance protein low > 74

Not shown: 7 genomes with orthologs for HER17_RS21560 only; 22 genomes with orthologs for HER17_RS06320 only