Conservation of cofitness between HER17_RS10870 and HER17_RS03085 in Pectobacterium carotovorum WPP14

55 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pectobacterium carotovorum WPP14 1.0 HER17_RS10870 HTH-type transcriptional regulator CysB 1.0 HER17_RS03085 2-isopropylmalate synthase 0.96 2
Dickeya dadantii 3937 0.95 DDA3937_RS10540 HTH-type transcriptional regulator CysB 0.89 DDA3937_RS18115 2-isopropylmalate synthase low > 74
Dickeya dianthicola ME23 0.95 DZA65_RS11020 HTH-type transcriptional regulator CysB 0.89 DZA65_RS19200 2-isopropylmalate synthase 0.66 20
Dickeya dianthicola 67-19 0.95 HGI48_RS10540 HTH-type transcriptional regulator CysB 0.89 HGI48_RS18055 2-isopropylmalate synthase low > 71
Serratia liquefaciens MT49 0.93 IAI46_13965 HTH-type transcriptional regulator CysB 0.84 IAI46_03355 2-isopropylmalate synthase — —
Rahnella sp. WP5 0.93 EX31_RS09890 HTH-type transcriptional regulator CysB 0.81 EX31_RS03680 2-isopropylmalate synthase 0.96 20
Klebsiella michiganensis M5al 0.92 BWI76_RS11930 LysR family transcriptional regulator CysB 0.85 BWI76_RS04680 2-isopropylmalate synthase — —
Erwinia tracheiphila SCR3 0.92 LU632_RS12550 cysB HTH-type transcriptional regulator CysB 0.81 LU632_RS02880 leuA 2-isopropylmalate synthase — —
Enterobacter sp. TBS_079 0.91 MPMX20_02501 HTH-type transcriptional regulator CysB 0.84 MPMX20_00769 2-isopropylmalate synthase — —
Escherichia coli ECOR38 0.91 HEPCGN_25600 cysB HTH-type transcriptional regulator CysB 0.85 HEPCGN_08695 2-isopropylmalate synthase 0.81 22
Enterobacter asburiae PDN3 0.91 EX28DRAFT_0946 Transcriptional regulator 0.84 EX28DRAFT_3670 2-isopropylmalate synthase (EC 2.3.3.13) — —
Escherichia coli BW25113 0.91 b1275 cysB DNA-binding transcriptional dual regulator, O-acetyl-L-serine-binding (NCBI) 0.85 b0074 leuA 2-isopropylmalate synthase (NCBI) — —
Escherichia fergusonii Becca 0.91 EFB2_02652 HTH-type transcriptional regulator CysB 0.85 EFB2_03971 2-isopropylmalate synthase — —
Escherichia coli ECRC100 0.91 OKFHMN_02600 cysB HTH-type transcriptional regulator CysB 0.85 OKFHMN_10715 2-isopropylmalate synthase — —
Escherichia coli ECRC101 0.91 MCAODC_15665 cysB HTH-type transcriptional regulator CysB 0.85 MCAODC_01230 2-isopropylmalate synthase — —
Escherichia coli ECRC62 0.91 BNILDI_18415 cysB HTH-type transcriptional regulator CysB 0.85 BNILDI_08550 2-isopropylmalate synthase — —
Escherichia coli Nissle 1917 0.91 ECOLIN_RS07680 HTH-type transcriptional regulator CysB 0.85 ECOLIN_RS00400 2-isopropylmalate synthase 0.53 15
Escherichia coli ECRC98 0.91 JDDGAC_05145 cysB HTH-type transcriptional regulator CysB 0.85 JDDGAC_14310 2-isopropylmalate synthase — —
Escherichia coli ECRC102 0.91 NIAGMN_26770 cysB HTH-type transcriptional regulator CysB 0.85 NIAGMN_08565 2-isopropylmalate synthase — —
Escherichia coli BL21 0.91 ECD_01251 N-acetylserine-responsive cysteine regulon transcriptional activator; autorepressor 0.85 ECD_00076 2-isopropylmalate synthase — —
Escherichia coli ECOR27 0.91 NOLOHH_20265 cysB HTH-type transcriptional regulator CysB 0.85 NOLOHH_03060 2-isopropylmalate synthase — —
Escherichia coli ECRC99 0.91 KEDOAH_26165 cysB HTH-type transcriptional regulator CysB 0.85 KEDOAH_17440 2-isopropylmalate synthase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.91 OHPLBJKB_02409 HTH-type transcriptional regulator CysB 0.85 OHPLBJKB_03583 2-isopropylmalate synthase low > 73
Pantoea sp. MT58 0.90 IAI47_09240 HTH-type transcriptional regulator CysB 0.81 IAI47_16000 2-isopropylmalate synthase 0.68 36
Vibrio cholerae E7946 ATCC 55056 0.80 CSW01_09545 HTH-type transcriptional regulator CysB 0.70 CSW01_12595 2-isopropylmalate synthase — —
Alteromonas macleodii MIT1002 0.78 MIT1002_02005 Cys regulon transcriptional activator 0.61 MIT1002_00949 2-isopropylmalate synthase — —
Shewanella amazonensis SB2B 0.75 Sama_1324 cysB transcriptional regulator CysB (RefSeq) 0.66 Sama_0335 2-isopropylmalate synthase (RefSeq) — —
Shewanella oneidensis MR-1 0.75 SO2649 cysB cys regulon transcriptional activator (NCBI ptt file) 0.65 SO4236 leuA 2-isopropylmalate synthase (NCBI ptt file) 0.84 18
Shewanella loihica PV-4 0.75 Shew_1624 cysB transcriptional regulator CysB (RefSeq) 0.65 Shew_3472 2-isopropylmalate synthase (RefSeq) — —
Shewanella sp. ANA-3 0.75 Shewana3_1731 cysB transcriptional regulator CysB (RefSeq) 0.65 Shewana3_3761 2-isopropylmalate synthase (RefSeq) — —
Pseudomonas putida KT2440 0.68 PP_2327 transcriptional dual regulator / CysB-O-acetyl-L-serine 0.10 PP_1025 2-isopropylmalate synthase 0.81 14
Marinobacter adhaerens HP15 0.68 HP15_1854 transcriptional regulator, LysR family 0.45 HP15_538 2-isopropylmalate synthase — —
Pseudomonas simiae WCS417 0.68 PS417_08460 CysB family transcriptional regulator 0.10 PS417_23110 2-isopropylmalate synthase — —
Pseudomonas fluorescens GW456-L13 0.68 PfGW456L13_2230 Cys regulon transcriptional activator CysB 0.10 PfGW456L13_4854 2-isopropylmalate synthase (EC 2.3.3.13) 0.90 9
Pseudomonas fluorescens FW300-N1B4 0.67 Pf1N1B4_283 Cys regulon transcriptional activator CysB 0.10 Pf1N1B4_847 2-isopropylmalate synthase (EC 2.3.3.13) — —
Pseudomonas sp. S08-1 0.67 OH686_01730 Cys regulon transcriptional activator CysB 0.11 OH686_17570 2-isopropylmalate synthase low > 80
Pseudomonas fluorescens SBW25 0.67 PFLU_RS08410 HTH-type transcriptional regulator CysB 0.10 PFLU_RS24765 2-isopropylmalate synthase low > 109
Pseudomonas fluorescens SBW25-INTG 0.67 PFLU_RS08410 HTH-type transcriptional regulator CysB 0.10 PFLU_RS24765 2-isopropylmalate synthase 0.41 21
Pseudomonas fluorescens FW300-N2E2 0.67 Pf6N2E2_2465 Cys regulon transcriptional activator CysB 0.10 Pf6N2E2_3170 2-isopropylmalate synthase (EC 2.3.3.13) 0.75 11
Pseudomonas fluorescens FW300-N2C3 0.67 AO356_03180 CysB family transcriptional regulator 0.10 AO356_06550 2-isopropylmalate synthase 0.50 24
Pseudomonas sp. RS175 0.67 PFR28_00966 HTH-type transcriptional regulator CysB 0.10 PFR28_00305 2-isopropylmalate synthase 0.35 58
Pseudomonas syringae pv. syringae B728a 0.66 Psyr_2077 regulatory protein, LysR:LysR, substrate-binding protein 0.10 Psyr_1257 2-isopropylmalate synthase 0.83 6
Pseudomonas syringae pv. syringae B728a ΔmexB 0.66 Psyr_2077 regulatory protein, LysR:LysR, substrate-binding protein 0.10 Psyr_1257 2-isopropylmalate synthase 0.64 44
Pseudomonas stutzeri RCH2 0.66 Psest_2329 Transcriptional regulator 0.47 Psest_1056 2-isopropylmalate synthase, bacterial type low > 67
Dechlorosoma suillum PS 0.52 Dsui_1988 transcriptional regulator 0.44 Dsui_3519 2-isopropylmalate synthase, bacterial type — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.46 GFF5044 Alkanesulfonate utilization operon LysR-family regulator CbI 0.41 GFF4281 2-isopropylmalate synthase (EC 2.3.3.13) low > 90
Variovorax sp. SCN45 0.43 GFF244 Cys regulon transcriptional activator CysB 0.40 GFF1165 2-isopropylmalate synthase (EC 2.3.3.13) low > 127
Variovorax sp. OAS795 0.43 ABID97_RS16600 CysB family HTH-type transcriptional regulator 0.41 ABID97_RS14910 2-isopropylmalate synthase low > 91
Castellaniella sp019104865 MT123 0.40 ABCV34_RS08230 CysB family HTH-type transcriptional regulator 0.11 ABCV34_RS12420 2-isopropylmalate synthase 0.61 4
Acidovorax sp. GW101-3H11 0.40 Ac3H11_2403 Alkanesulfonate utilization operon LysR-family regulator CbI 0.41 Ac3H11_530 2-isopropylmalate synthase (EC 2.3.3.13) low > 79
Rhodanobacter sp. FW510-T8 0.37 OKGIIK_05975 lysR CysB family transcriptional regulator 0.39 OKGIIK_13575 leuA 2-isopropylmalate synthase low > 52
Rhodanobacter denitrificans MT42 0.36 LRK55_RS00690 LysR substrate-binding domain-containing protein 0.40 LRK55_RS09985 2-isopropylmalate synthase low > 63
Rhodanobacter denitrificans FW104-10B01 0.36 LRK54_RS00915 LysR substrate-binding domain-containing protein 0.40 LRK54_RS10345 2-isopropylmalate synthase 0.69 19
Dyella japonica UNC79MFTsu3.2 0.35 ABZR86_RS05885 LysR substrate-binding domain-containing protein 0.41 ABZR86_RS15970 2-isopropylmalate synthase 0.97 10
Lysobacter sp. OAE881 0.34 ABIE51_RS15850 LysR family transcriptional regulator 0.40 ABIE51_RS17570 2-isopropylmalate synthase 0.88 57
Xanthomonas campestris pv. campestris strain 8004 0.30 Xcc-8004.1249.1 Transcriptional regulator 0.37 Xcc-8004.1056.1 2-isopropylmalate synthase (EC 2.3.3.13) low > 74

Not shown: 4 genomes with orthologs for HER17_RS10870 only; 35 genomes with orthologs for HER17_RS03085 only