Conservation of cofitness between HEPCGN_02885 and HEPCGN_08675 in Escherichia coli ECOR38

59 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli ECOR38 1.0 HEPCGN_02885 mdtB multidrug efflux RND transporter permease subunit MdtB 1.0 HEPCGN_08675 ilvN acetolactate synthase small subunit 0.70 3
Escherichia coli ECRC100 1.00 OKFHMN_24195 mdtB multidrug efflux RND transporter permease subunit MdtB 0.99 OKFHMN_10695 ilvN acetolactate synthase small subunit low > 80
Escherichia coli ECRC98 1.00 JDDGAC_28305 mdtB multidrug efflux RND transporter permease subunit MdtB 0.99 JDDGAC_14290 ilvN acetolactate synthase small subunit low > 86
Escherichia coli ECRC99 1.00 KEDOAH_03955 mdtB multidrug efflux RND transporter permease subunit MdtB 0.99 KEDOAH_17460 ilvN acetolactate synthase small subunit
Escherichia coli ECRC102 1.00 NIAGMN_22140 mdtB multidrug efflux RND transporter permease subunit MdtB 0.99 NIAGMN_08545 ilvN acetolactate synthase small subunit
Escherichia coli ECOR27 1.00 NOLOHH_15540 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 NOLOHH_03040 ilvN acetolactate synthase small subunit low > 75
Escherichia coli Nissle 1917 1.00 ECOLIN_RS12200 multidrug efflux RND transporter permease subunit MdtB 1.00 ECOLIN_RS00420 acetolactate synthase small subunit low > 55
Escherichia coli BW25113 1.00 b2075 mdtB multidrug efflux system, subunit B (NCBI) 0.99 b0078 ilvH acetolactate synthase small subunit (NCBI) low > 76
Escherichia coli ECRC101 1.00 MCAODC_20745 mdtB multidrug efflux RND transporter permease subunit MdtB 0.99 MCAODC_01210 ilvN acetolactate synthase small subunit low > 87
Escherichia fergusonii Becca 1.00 EFB2_01780 Multidrug resistance protein MdtB 1.00 EFB2_03968 Acetolactate synthase isozyme 3 small subunit low > 86
Escherichia coli ECRC62 0.99 BNILDI_14455 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 BNILDI_08570 ilvN acetolactate synthase small subunit low > 75
Escherichia coli HS(pFamp)R (ATCC 700891) 0.99 OHPLBJKB_01629 Multidrug resistance protein MdtB 1.00 OHPLBJKB_03580 Acetolactate synthase isozyme 3 small subunit low > 73
Escherichia coli BL21 0.99 ECD_01980 multidrug efflux system, subunit B 0.99 ECD_00080 acetolactate synthase 3, small subunit, valine-sensitive low > 61
Klebsiella michiganensis M5al 0.90 BWI76_RS19255 multidrug transporter subunit MdtB 0.97 BWI76_RS04700 acetolactate synthase small subunit low > 92
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.90 GFF3854 Multidrug transporter MdtB 0.98 GFF160 Acetolactate synthase small subunit (EC 2.2.1.6) low > 78
Enterobacter sp. TBS_079 0.90 MPMX20_03061 Multidrug resistance protein MdtB 0.96 MPMX20_00772 Acetolactate synthase isozyme 3 small subunit low > 85
Enterobacter asburiae PDN3 0.89 EX28DRAFT_0483 Cation/multidrug efflux pump 0.96 EX28DRAFT_3674 acetolactate synthase, small subunit (EC 2.2.1.6) low > 76
Serratia liquefaciens MT49 0.81 IAI46_18975 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.92 IAI46_03380 acetolactate synthase small subunit low > 86
Pantoea sp. MT58 0.81 IAI47_06870 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.94 IAI47_15985 acetolactate synthase small subunit low > 76
Erwinia tracheiphila SCR3 0.79 LU632_RS08690 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.92 LU632_RS02890 ilvN acetolactate synthase small subunit low > 74
Pectobacterium carotovorum WPP14 0.79 HER17_RS06320 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.92 HER17_RS03100 acetolactate synthase small subunit low > 75
Dickeya dadantii 3937 0.77 DDA3937_RS15265 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.91 DDA3937_RS18100 acetolactate synthase small subunit low > 74
Dickeya dianthicola ME23 0.77 DZA65_RS16165 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.92 DZA65_RS19180 acetolactate synthase small subunit low > 75
Dickeya dianthicola 67-19 0.76 HGI48_RS15345 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.92 HGI48_RS18035 acetolactate synthase small subunit low > 71
Herbaspirillum seropedicae SmR1 0.68 HSERO_RS07650 multidrug transporter 0.61 HSERO_RS08655 acetolactate synthase low > 78
Ralstonia solanacearum UW163 0.65 UW163_RS21010 multidrug transporter subunit MdtB 0.61 UW163_RS10680 acetolactate synthase small subunit
Ralstonia solanacearum IBSBF1503 0.65 RALBFv3_RS18120 multidrug transporter subunit MdtB 0.61 RALBFv3_RS03045 acetolactate synthase small subunit low > 76
Ralstonia solanacearum PSI07 0.65 RPSI07_RS05515 multidrug transporter subunit MdtB 0.61 RPSI07_RS14260 acetolactate synthase small subunit low > 81
Ralstonia sp. UNC404CL21Col 0.65 ABZR87_RS19025 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.62 ABZR87_RS14950 acetolactate synthase small subunit low > 80
Ralstonia solanacearum GMI1000 0.65 RS_RS22915 multidrug transporter subunit MdtB 0.61 RS_RS10415 acetolactate synthase small subunit low > 80
Cupriavidus basilensis FW507-4G11 0.64 RR42_RS03310 multidrug transporter 0.61 RR42_RS05440 acetolactate synthase
Pseudomonas sp. RS175 0.62 PFR28_02194 Multidrug resistance protein MdtB 0.67 PFR28_03698 Acetolactate synthase isozyme 3 small subunit low > 88
Pseudomonas fluorescens FW300-N2C3 0.62 AO356_25875 multidrug transporter 0.67 AO356_16175 acetolactate synthase 3 regulatory subunit low > 104
Rahnella sp. WP5 0.62 EX31_RS13380 MMPL family transporter 0.94 EX31_RS03660 acetolactate synthase small subunit low > 89
Pseudomonas fluorescens FW300-N2E2 0.62 Pf6N2E2_1272 Acriflavin resistance plasma membrane protein 0.67 Pf6N2E2_5176 Acetolactate synthase small subunit (EC 2.2.1.6) low > 103
Pseudomonas putida KT2440 0.62 PP_3584 multidrug efflux transport system - membrane subunit 0.68 PP_4679 acetohydroxybutanoate synthase / acetolactate synthase low > 96
Pseudomonas sp. S08-1 0.62 OH686_00925 Multidrug efflux system MdtABC-TolC, inner-membrane proton/drug antiporter MdtB (RND type) 0.67 OH686_08125 acetolactate synthase, small subunit low > 80
Pseudomonas fluorescens GW456-L13 0.62 PfGW456L13_3266 Acriflavin resistance plasma membrane protein 0.67 PfGW456L13_1539 Acetolactate synthase small subunit (EC 2.2.1.6) low > 87
Pseudomonas fluorescens FW300-N2E3 0.62 AO353_22895 multidrug transporter 0.67 AO353_14500 acetolactate synthase 3 regulatory subunit low > 101
Pseudomonas fluorescens SBW25-INTG 0.61 PFLU_RS13430 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.67 PFLU_RS25645 acetolactate synthase small subunit 0.22 80
Pseudomonas fluorescens SBW25 0.61 PFLU_RS13430 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.67 PFLU_RS25645 acetolactate synthase small subunit low > 109
Pseudomonas simiae WCS417 0.61 PS417_12745 multidrug transporter 0.67 PS417_23805 acetolactate synthase 3 regulatory subunit low > 88
Pseudomonas fluorescens FW300-N1B4 0.61 Pf1N1B4_4665 Acriflavin resistance plasma membrane protein 0.67 Pf1N1B4_2879 Acetolactate synthase small subunit (EC 2.2.1.6) low > 87
Paraburkholderia sabiae LMG 24235 0.60 QEN71_RS23305 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.61 QEN71_RS24220 acetolactate synthase small subunit 0.54 69
Paraburkholderia bryophila 376MFSha3.1 0.59 H281DRAFT_06492 multidrug efflux pump 0.61 H281DRAFT_04552 acetolactate synthase, small subunit low > 103
Acidovorax sp. GW101-3H11 0.59 Ac3H11_3618 Cobalt-zinc-cadmium resistance protein CzcA; Cation efflux system protein CusA 0.60 Ac3H11_526 Acetolactate synthase small subunit (EC 2.2.1.6) low > 79
Pseudomonas syringae pv. syringae B728a 0.59 Psyr_2483 Acriflavin resistance protein 0.68 Psyr_0847 acetolactate synthase, small subunit low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.59 Psyr_2483 Acriflavin resistance protein 0.68 Psyr_0847 acetolactate synthase, small subunit low > 86
Pseudomonas stutzeri RCH2 0.59 Psest_2139 Cation/multidrug efflux pump 0.69 Psest_1037 acetolactate synthase, small subunit low > 67
Burkholderia phytofirmans PsJN 0.58 BPHYT_RS07785 multidrug transporter 0.61 BPHYT_RS06550 acetolactate synthase low > 109
Paraburkholderia graminis OAS925 0.58 ABIE53_001783 multidrug efflux pump 0.61 ABIE53_001575 acetolactate synthase-1/3 small subunit low > 113
Castellaniella sp019104865 MT123 0.57 ABCV34_RS14620 multidrug efflux RND transporter permease subunit 0.57 ABCV34_RS01215 acetolactate synthase small subunit low > 48
Variovorax sp. SCN45 0.56 GFF6659 Multidrug efflux system MdtABC-TolC, inner-membrane proton/drug antiporter MdtB (RND type) 0.58 GFF1159 Acetolactate synthase small subunit (EC 2.2.1.6) low > 127
Hydrogenophaga sp. GW460-11-11-14-LB1 0.55 GFF487 Cobalt-zinc-cadmium resistance protein CzcA; Cation efflux system protein CusA 0.61 GFF4277 Acetolactate synthase small subunit (EC 2.2.1.6) low > 90
Variovorax sp. OAS795 0.54 ABID97_RS20855 efflux RND transporter permease subunit 0.59 ABID97_RS14890 acetolactate synthase small subunit low > 91
Azospirillum sp. SherDot2 0.53 MPMX19_05477 Multidrug resistance protein MdtB 0.39 MPMX19_01775 Acetolactate synthase isozyme 3 small subunit
Magnetospirillum magneticum AMB-1 0.52 AMB_RS17370 acriflavine resistance protein B 0.41 AMB_RS17745 acetolactate synthase small subunit
Rhodopseudomonas palustris CGA009 0.49 TX73_013310 efflux RND transporter permease subunit 0.38 TX73_010470 acetolactate synthase small subunit low > 86
Parabacteroides merdae CL09T00C40 0.24 HMPREF1078_RS05470 efflux RND transporter permease subunit 0.19 HMPREF1078_RS16685 acetolactate synthase small subunit 0.57 1
Phaeobacter inhibens DSM 17395 0.13 PGA1_78p00510 multidrug transporter MdtB 0.41 PGA1_c20220 acetolactate synthase isozyme 3 small subunit low > 62

Not shown: 5 genomes with orthologs for HEPCGN_02885 only; 30 genomes with orthologs for HEPCGN_08675 only