| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Sphingobium sp. HT1-2 | 1.0 | GFF1142 | | Xanthine/uracil/thiamine/ascorbate permease family protein | 1.0 | GFF1825 | | Two-component transcriptional response regulator, NarL/FixJ family | 0.68 | 12 |
| Caulobacter crescentus NA1000 Δfur | 0.57 | CCNA_00186 | | guanine-hypoxanthine permease | 0.22 | CCNA_01208 | | two-component response regulator | low | > 67 |
| Caulobacter crescentus NA1000 | 0.57 | CCNA_00186 | | guanine-hypoxanthine permease | 0.22 | CCNA_01208 | | two-component response regulator | low | > 66 |
| Pseudomonas segetis P6 | 0.49 | ACVTMO_RS19810 | | NCS2 family permease | 0.25 | ACVTMO_RS12520 | gacA | response regulator transcription factor GacA | low | > 75 |
| Pseudomonas sp. SVBP6 | 0.49 | COO64_RS02865 | | NCS2 family permease | 0.26 | COO64_RS13925 | uvrY | UvrY/SirA/GacA family response regulator transcription factor | low | > 93 |
| Pseudomonas putida KT2440 | 0.49 | PP_4653 | | adenine:H+ symporter | 0.26 | PP_4099 | | two-componenent system BarA/UvrY - regulatory subunit | low | > 96 |
| Pseudomonas sp. BP01 | 0.49 | JOY50_RS27495 | | NCS2 family permease | 0.26 | JOY50_RS06870 | uvrY | UvrY/SirA/GacA family response regulator transcription factor | low | > 84 |
| Pseudomonas simiae WCS417 | 0.48 | PS417_24380 | | guanine permease | 0.25 | PS417_10720 | | chemotaxis protein CheY | low | > 88 |
| Pseudomonas sp. RS175 | 0.48 | PFR28_03808 | | Adenine permease AdeP | 0.26 | PFR28_01868 | | Transcriptional regulatory protein DegU | — | — |
| Pseudomonas fluorescens SBW25 | 0.48 | PFLU_RS26300 | | NCS2 family permease | 0.25 | PFLU_RS10765 | | UvrY/SirA/GacA family response regulator transcription factor | low | > 109 |
| Pseudomonas fluorescens SBW25-INTG | 0.48 | PFLU_RS26300 | | NCS2 family permease | 0.25 | PFLU_RS10765 | | UvrY/SirA/GacA family response regulator transcription factor | low | > 109 |
| Pseudomonas syringae pv. syringae B728a | 0.48 | Psyr_4286 | | Xanthine/uracil/vitamin C permease | 0.25 | Psyr_2897 | | regulatory protein, LuxR:Response regulator receiver | low | > 86 |
| Pseudomonas orientalis W4I3 | 0.48 | QF045_RS26675 | | NCS2 family permease | 0.25 | QF045_RS12800 | | UvrY/SirA/GacA family response regulator transcription factor | low | > 93 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.48 | Psyr_4286 | | Xanthine/uracil/vitamin C permease | 0.25 | Psyr_2897 | | regulatory protein, LuxR:Response regulator receiver | low | > 86 |
| Pseudomonas fluorescens GW456-L13 | 0.48 | PfGW456L13_1431 | | Xanthine/uracil/thiamine/ascorbate permease family protein | 0.23 | PfGW456L13_1209 | | DNA-binding response regulator, LuxR family, near polyamine transporter | low | > 87 |
| Pantoea agglomerans CFBP13505 P0401 | 0.48 | PagCFBP13505_RS01745 | | NCS2 family permease | 0.26 | PagCFBP13505_RS19860 | | two-component system response regulator NarL | low | > 74 |
| Pantoea sp. MT58 | 0.48 | IAI47_07860 | | NCS2 family permease | 0.27 | IAI47_05315 | | response regulator | low | > 76 |
| Acinetobacter baumannii LAC-4 | 0.47 | RR41_RS09965 | | NCS2 family permease | 0.22 | RR41_RS17790 | | response regulator | low | > 55 |
| Pseudomonas sp. DMC3 | 0.47 | GFF3939 | | Adenine permease AdeQ | 0.24 | GFF28 | | Response regulator UvrY | low | > 89 |
| Acinetobacter radioresistens SK82 | 0.47 | MPMX26_01078 | | Adenine permease AdeP | 0.24 | MPMX26_00164 | | Response regulator GacA | low | > 36 |
| Rahnella sp. WP5 | 0.47 | EX31_RS07080 | | NCS2 family permease | 0.27 | EX31_RS24145 | | UvrY/SirA/GacA family response regulator transcription factor | low | > 89 |
| Vibrio cholerae E7946 ATCC 55056 | 0.47 | CSW01_11595 | | NCS2 family permease | 0.27 | CSW01_06135 | | two-component system response regulator UvrY | — | — |
| Pseudomonas aeruginosa PA14 | 0.47 | IKLFDK_30020 | | guanine permease | 0.29 | IKLFDK_19985 | | two-component system response regulator NarL | — | — |
| Pseudomonas aeruginosa MRSN321 | 0.47 | DY961_RS09330 | | solute carrier family 23 protein | 0.29 | DY961_RS13490 | narL;go_function=DNA | two-component system response regulator NarL | low | > 100 |
| Pseudomonas aeruginosa PUPa3 | 0.47 | DQ20_RS52700 | | solute carrier family 23 protein | 0.29 | DQ20_RS48785 | narL;go_function=DNA | two-component system response regulator NarL | low | > 101 |
| Variovorax sp. OAS795 | 0.47 | ABID97_RS22110 | | NCS2 family permease | 0.28 | ABID97_RS28185 | | response regulator transcription factor | low | > 91 |
| Variovorax sp. SCN45 | 0.46 | GFF1843 | | Xanthine/uracil/thiamine/ascorbate permease family protein | 0.25 | GFF2564 | | Two-component transcriptional response regulator, LuxR family | low | > 127 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.46 | H281DRAFT_01209 | | putative MFS transporter, AGZA family, xanthine/uracil permease | 0.25 | H281DRAFT_01334 | | two component transcriptional regulator, LuxR family | — | — |
| Paraburkholderia graminis OAS925 | 0.46 | ABIE53_005727 | | AGZA family xanthine/uracil permease-like MFS transporter | 0.25 | ABIE53_005478 | | two-component system invasion response regulator UvrY | low | > 113 |
| Pseudomonas stutzeri RCH2 | 0.46 | Psest_3450 | | Permeases | 0.26 | Psest_2260 | | Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain | low | > 67 |
| Shewanella amazonensis SB2B | 0.45 | Sama_2517 | | xanthine/uracil permease family protein (RefSeq) | 0.26 | Sama_0646 | | response regulator receiver protein (RefSeq) | low | > 62 |
| Shewanella oneidensis MR-1 | 0.45 | SO1120 | | xanthine/uracil permease family protein (NCBI ptt file) | 0.27 | SO1860 | | DNA-binding response regulator, LuxR family (NCBI ptt file) | low | > 76 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.45 | GFF1740 | | Xanthine/uracil/thiamine/ascorbate permease family protein | 0.28 | GFF1492 | | Nitrate/nitrite response regulator protein | — | — |
| Marinobacter adhaerens HP15 | 0.44 | HP15_2548 | | xanthine/uracil permease family protein | 0.24 | HP15_1567 | | two component transcriptional regulator, LuxR family | low | > 73 |
| Shewanella sp. ANA-3 | 0.44 | Shewana3_0953 | | xanthine/uracil/vitamin C permease (RefSeq) | 0.27 | Shewana3_1608 | | response regulator (RefSeq) | low | > 73 |
| Shewanella loihica PV-4 | 0.44 | Shew_2849 | | xanthine/uracil/vitamin C permease (RefSeq) | 0.26 | Shew_0842 | | two component LuxR family transcriptional regulator (RefSeq) | low | > 60 |
| Enterobacter asburiae PDN3 | 0.44 | EX28DRAFT_3998 | | Permeases | 0.24 | EX28DRAFT_0633 | | two component transcriptional regulator, LuxR family | low | > 76 |
| Enterobacter sp. TBS_079 | 0.44 | MPMX20_04645 | | Adenine permease AdeP | 0.24 | MPMX20_02839 | | Response regulator UvrY | 0.21 | 4 |
| Dickeya dianthicola 67-19 | 0.43 | HGI48_RS21605 | | NCS2 family permease | 0.26 | HGI48_RS13800 | | UvrY/SirA/GacA family response regulator transcription factor | low | > 71 |
| Dickeya dianthicola ME23 | 0.43 | DZA65_RS22590 | | NCS2 family permease | 0.26 | DZA65_RS14290 | | UvrY/SirA/GacA family response regulator transcription factor | low | > 75 |
| Dickeya dadantii 3937 | 0.43 | DDA3937_RS21425 | | NCS2 family permease | 0.26 | DDA3937_RS13705 | | UvrY/SirA/GacA family response regulator transcription factor | low | > 74 |
| Escherichia fergusonii Becca | 0.43 | EFB2_04918 | | Adenine permease AdeP | 0.28 | EFB2_01663 | | Nitrate/nitrite response regulator protein NarL | low | > 86 |
| Escherichia coli Nissle 1917 | 0.43 | ECOLIN_RS21385 | | adenine permease AdeP | 0.28 | ECOLIN_RS12820 | | nitrate/nitrite response regulator protein NarP | — | — |
| Escherichia coli ECRC62 | 0.42 | BNILDI_04445 | adeP | adenine permease AdeP | 0.28 | BNILDI_13815 | narP | nitrate/nitrite response regulator protein NarP | low | > 75 |
| Escherichia coli ECOR27 | 0.42 | NOLOHH_07085 | adeP | adenine permease AdeP | 0.28 | NOLOHH_14895 | narP | nitrate/nitrite response regulator protein NarP | low | > 76 |
| Escherichia coli ECRC100 | 0.42 | OKFHMN_14935 | adeP | adenine permease AdeP | 0.28 | OKFHMN_23320 | narP | nitrate/nitrite response regulator protein NarP | low | > 79 |
| Escherichia coli BW25113 | 0.42 | b3714 | yieG | predicted inner membrane protein (NCBI) | 0.28 | b2193 | narP | DNA-binding response regulator in two-component regulatory system with NarQ or NarX (NCBI) | low | > 76 |
| Escherichia coli BL21 | 0.42 | ECD_03598 | | adenine permease, high affinity; adenine:H+ symporter | 0.28 | ECD_02120 | | response regulator in two-component regulatory system with NarQ | low | > 61 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.42 | OHPLBJKB_04339 | | Adenine permease AdeP | 0.28 | OHPLBJKB_01518 | | Nitrate/nitrite response regulator protein NarL | low | > 74 |
| Escherichia coli ECRC101 | 0.42 | MCAODC_05445 | adeP | adenine permease AdeP | 0.28 | MCAODC_14370 | narP | nitrate/nitrite response regulator protein NarP | low | > 87 |
| Serratia liquefaciens MT49 | 0.42 | IAI46_25220 | | NCS2 family permease | 0.28 | IAI46_18680 | | two-component system response regulator NarL | low | > 87 |
| Escherichia coli ECRC99 | 0.42 | KEDOAH_13215 | adeP | adenine permease AdeP | 0.28 | KEDOAH_04865 | narP | nitrate/nitrite response regulator protein NarP | — | — |
| Escherichia coli ECOR38 | 0.42 | HEPCGN_13640 | adeP | adenine permease AdeP | 0.28 | HEPCGN_22585 | narP | nitrate/nitrite response regulator protein NarP | low | > 88 |
| Escherichia coli ECRC102 | 0.42 | NIAGMN_12690 | adeP | adenine permease AdeP | 0.28 | NIAGMN_21085 | narP | nitrate/nitrite response regulator protein NarP | low | > 80 |
| Escherichia coli ECRC98 | 0.42 | JDDGAC_18555 | adeP | adenine permease AdeP | 0.28 | JDDGAC_27280 | narP | nitrate/nitrite response regulator protein NarP | low | > 87 |
| Klebsiella michiganensis M5al | 0.42 | BWI76_RS00110 | | adenine permease PurP | 0.24 | BWI76_RS18335 | | DNA-binding response regulator | low | > 92 |
| Rhizobium sp. OAE497 | 0.42 | ABIE40_RS25255 | | NCS2 family permease | 0.24 | ABIE40_RS23610 | | response regulator transcription factor | low | > 107 |
| Sinorhizobium meliloti 1021 | 0.42 | SM_b21281 | | xanthine uracil permease | 0.25 | SM_b21520 | | two-component response regulator protein | low | > 103 |
| Erwinia amylovora T8 | 0.42 | OLJFJH_05200 | | adenine permease PurP | 0.27 | OLJFJH_15795 | | UvrY/SirA/GacA family response regulator transcription factor | low | > 58 |
| Castellaniella sp019104865 MT123 | 0.41 | ABCV34_RS03015 | | NCS2 family permease | 0.25 | ABCV34_RS08970 | | response regulator transcription factor | low | > 48 |
| Alteromonas macleodii MIT1002 | 0.41 | MIT1002_01579 | | putative adenine permease PurP | 0.25 | MIT1002_03123 | | Protease production enhancer protein | low | > 70 |
| Pectobacterium carotovorum WPP14 | 0.41 | HER17_RS21740 | | NCS2 family permease | 0.28 | HER17_RS09115 | | nitrate/nitrite response regulator protein NarP | low | > 75 |
| Lysobacter sp. OAE881 | 0.40 | ABIE51_RS04590 | | NCS2 family permease | 0.55 | ABIE51_RS10620 | | response regulator transcription factor | low | > 62 |
| Xanthomonas campestris pv. campestris strain 8004 | 0.37 | Xcc-8004.378.1 | | Xanthine/uracil/thiamine/ascorbate permease family protein | 0.50 | Xcc-8004.2397.1 | | two-component system regulatory protein | low | > 74 |
| Bifidobacterium breve UCC2003 | 0.34 | BBR_RS19145 | | NCS2 family permease | 0.23 | BBR_RS14610 | | DNA-binding response regulator | low | > 34 |
| Erwinia tracheiphila HP pepo 2.2 | 0.26 | IJEDHG_11255 | | permease | 0.25 | IJEDHG_20735 | uvrY | UvrY/SirA/GacA family response regulator transcription factor | — | — |
| Erwinia tracheiphila SCR3 | 0.26 | LU632_RS23270 | | NCS2 family permease | 0.25 | LU632_RS10190 | uvrY | UvrY/SirA/GacA family response regulator transcription factor | — | — |
Not shown: 25 genomes with orthologs for GFF1142 only; 16 genomes with orthologs for GFF1825 only