Conservation of cofitness between ECD_00652 and ECD_04089 in Escherichia coli BL21

63 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BL21 1.0 ECD_00652 fused sensory histidine kinase in two-component regulatory system with KdpE: signal sensing protein 1.0 ECD_04089 UPF0053 family inner membrane protein low > 61
Escherichia coli ECRC101 1.00 MCAODC_26290 kdpD two-component system sensor histidine kinase KdpD 1.00 MCAODC_02530 paeA Polyamine export protein 0.51 48
Escherichia coli ECRC99 1.00 KEDOAH_20895 kdpD two-component system sensor histidine kinase KdpD 1.00 KEDOAH_16140 paeA Polyamine export protein — —
Escherichia coli ECRC100 1.00 OKFHMN_07075 kdpD two-component system sensor histidine kinase KdpD 1.00 OKFHMN_12015 paeA Polyamine export protein low > 80
Escherichia coli ECRC102 1.00 NIAGMN_05130 kdpD two-component system sensor histidine kinase KdpD 1.00 NIAGMN_09865 paeA Polyamine export protein — —
Escherichia coli ECRC98 1.00 JDDGAC_10725 kdpD two-component system sensor histidine kinase KdpD 1.00 JDDGAC_15655 paeA Polyamine export protein low > 86
Escherichia coli ECOR38 1.00 HEPCGN_01160 kdpD two-component system sensor histidine kinase KdpD 1.00 HEPCGN_10215 paeA Polyamine export protein low > 87
Escherichia coli BW25113 1.00 b0695 kdpD fused sensory histidine kinase in two-component regulatory system with KdpE: signal sensing protein (NCBI) 1.00 b4218 ytfL predicted inner membrane protein (NCBI) low > 76
Escherichia coli ECOR27 1.00 NOLOHH_23455 kdpD two-component system sensor histidine kinase KdpD 1.00 NOLOHH_04280 paeA Polyamine export protein low > 75
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_03022 Sensor protein KdpD 1.00 OHPLBJKB_03816 hypothetical protein low > 73
Escherichia coli ECRC62 1.00 BNILDI_21460 kdpD two-component system sensor histidine kinase KdpD 1.00 BNILDI_07240 tlyC Polyamine export protein low > 75
Escherichia coli Nissle 1917 0.99 ECOLIN_RS03755 two-component system sensor histidine kinase KdpD 1.00 ECOLIN_RS24495 hemolysin family protein 0.29 31
Escherichia fergusonii Becca 0.99 EFB2_03401 Sensor protein KdpD 1.00 EFB2_04311 hypothetical protein low > 86
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.88 GFF4607 Osmosensitive K+ channel histidine kinase KdpD (EC 2.7.3.-) 0.93 GFF871 Putative membrane protein 0.39 78
Enterobacter asburiae PDN3 0.83 EX28DRAFT_2283 Osmosensitive K+ channel histidine kinase 0.94 EX28DRAFT_3404 Hemolysins and related proteins containing CBS domains low > 76
Enterobacter sp. TBS_079 0.83 MPMX20_01338 Sensor protein KdpD 0.93 MPMX20_00495 hypothetical protein low > 85
Klebsiella michiganensis M5al 0.83 BWI76_RS08305 two-component sensor histidine kinase 0.92 BWI76_RS02765 membrane protein 0.18 79
Rahnella sp. WP5 0.68 EX31_RS23335 two-component system sensor histidine kinase KdbD 0.80 EX31_RS08705 HlyC/CorC family transporter low > 89
Serratia liquefaciens MT49 0.68 IAI46_06165 two-component system sensor histidine kinase KdbD 0.82 IAI46_01760 HlyC/CorC family transporter low > 86
Pectobacterium carotovorum WPP14 0.66 HER17_RS15045 two-component system sensor histidine kinase KdpD 0.77 HER17_RS03970 hemolysin family protein low > 75
Pantoea sp. MT58 0.66 IAI47_01250 two-component system sensor histidine kinase KdbD 0.83 IAI47_02710 HlyC/CorC family transporter low > 76
Erwinia tracheiphila SCR3 0.66 LU632_RS00800 kdpD two-component system sensor histidine kinase KdpD 0.81 LU632_RS02100 hemolysin family protein low > 74
Dickeya dadantii 3937 0.65 DDA3937_RS06370 two-component system sensor histidine kinase KdpD 0.77 DDA3937_RS17170 HlyC/CorC family transporter low > 74
Dickeya dianthicola 67-19 0.65 HGI48_RS06415 two-component system sensor histidine kinase KdpD 0.77 HGI48_RS17225 HlyC/CorC family transporter low > 71
Dickeya dianthicola ME23 0.65 DZA65_RS06760 two-component system sensor histidine kinase KdbD 0.77 DZA65_RS18310 HlyC/CorC family transporter low > 75
Pseudomonas fluorescens FW300-N2E3 0.50 AO353_28955 sensor protein KdpD 0.11 AO353_09865 hypothetical protein low > 101
Dechlorosoma suillum PS 0.45 Dsui_0272 osmosensitive K+ channel histidine kinase 0.29 Dsui_3105 CBS domain-containing protein low > 51
Cupriavidus basilensis FW507-4G11 0.42 RR42_RS00495 histidine kinase 0.44 RR42_RS04375 magnesium transporter low > 128
Acidovorax sp. GW101-3H11 0.41 Ac3H11_2408 Osmosensitive K+ channel histidine kinase KdpD (EC 2.7.3.-) 0.54 Ac3H11_4775 Putative membrane protein low > 79
Ralstonia solanacearum PSI07 0.40 RPSI07_RS08140 sensor histidine kinase KdpD 0.45 RPSI07_RS13270 HlyC/CorC family transporter low > 81
Ralstonia solanacearum GMI1000 0.40 RS_RS16960 sensor histidine kinase KdpD 0.45 RS_RS11430 HlyC/CorC family transporter 0.47 4
Ralstonia solanacearum UW163 0.40 UW163_RS04465 sensor histidine kinase KdpD 0.44 UW163_RS09720 HlyC/CorC family transporter — —
Ralstonia solanacearum IBSBF1503 0.40 RALBFv3_RS09130 sensor histidine kinase KdpD 0.44 RALBFv3_RS03950 HlyC/CorC family transporter low > 76
Variovorax sp. SCN45 0.40 GFF3520 Osmosensitive K+ channel histidine kinase KdpD 0.54 GFF2520 UPF0053 inner membrane protein YtfL low > 127
Herbaspirillum seropedicae SmR1 0.39 HSERO_RS18855 sensor protein KdpD 0.51 HSERO_RS08405 membrane protein low > 78
Variovorax sp. OAS795 0.39 ABID97_RS01010 DUF4118 domain-containing protein 0.55 ABID97_RS07170 hemolysin family protein low > 91
Ralstonia sp. UNC404CL21Col 0.39 ABZR87_RS04525 sensor histidine kinase KdpD 0.46 ABZR87_RS15885 hemolysin family protein low > 80
Agrobacterium fabrum C58 0.34 Atu3787 two component sensor kinase 0.21 Atu3732 hemolysin low > 89
Rhizobium sp. OAE497 0.33 ABIE40_RS24610 sensor histidine kinase KdpD 0.22 ABIE40_RS21835 hemolysin family protein 0.29 9
Azospirillum brasilense Sp245 0.33 AZOBR_RS23975 histidine kinase 0.29 AZOBR_RS16970 hypothetical protein low > 97
Rhodopseudomonas palustris CGA009 0.31 TX73_015550 sensor histidine kinase KdpD 0.22 TX73_014560 hemolysin family protein low > 86
Azospirillum sp. SherDot2 0.31 MPMX19_03748 Sensor protein KdpD 0.27 MPMX19_04101 hypothetical protein low > 112
Magnetospirillum magneticum AMB-1 0.31 AMB_RS09655 sensor histidine kinase KdpD 0.25 AMB_RS10875 HlyC/CorC family transporter low > 64
Rhodospirillum rubrum S1H 0.31 Rru_A1158 Osmosensitive K+ channel Signal Transduction Histidine Kinase (NCBI) 0.26 Rru_A0756 hypothetical protein (NCBI) low > 58
Bosea sp. OAE506 0.30 ABIE41_RS24230 sensor histidine kinase KdpD 0.20 ABIE41_RS13905 hemolysin family protein low > 77
Dyella japonica UNC79MFTsu3.2 0.28 ABZR86_RS13210 sensor histidine kinase KdpD 0.25 ABZR86_RS19900 hemolysin family protein low > 74
Pseudomonas fluorescens FW300-N2E2 0.28 Pf6N2E2_2491 Osmosensitive K+ channel histidine kinase KdpD (EC 2.7.3.-) 0.11 Pf6N2E2_4068 Phosphate regulon metal ion transporter containing CBS domains 0.16 78
Pseudomonas sp. RS175 0.27 PFR28_00942 Sensor protein KdpD 0.11 PFR28_04481 hypothetical protein low > 88
Sinorhizobium meliloti 1021 0.27 SMa2327 sensor protein 0.26 SMc00240 hypothetical protein low > 103
Sphingomonas koreensis DSMZ 15582 0.27 Ga0059261_3881 Osmosensitive K+ channel histidine kinase 0.26 Ga0059261_1443 Hemolysins and related proteins containing CBS domains low > 68
Caulobacter crescentus NA1000 0.27 CCNA_01666 osmosensitive K+ channel histidine kinase kdpD 0.23 CCNA_00369 magnesium and cobalt efflux protein corC-like protein low > 66
Caulobacter crescentus NA1000 Δfur 0.27 CCNA_01666 osmosensitive K+ channel histidine kinase kdpD 0.23 CCNA_00369 magnesium and cobalt efflux protein corC-like protein low > 67
Hydrogenophaga sp. GW460-11-11-14-LB1 0.26 GFF4474 Osmosensitive K+ channel histidine kinase KdpD (EC 2.7.3.-) 0.27 GFF224 Magnesium and cobalt efflux protein CorC low > 90
Pseudomonas fluorescens GW456-L13 0.26 PfGW456L13_2204 Osmosensitive K+ channel histidine kinase KdpD (EC 2.7.3.-) 0.11 PfGW456L13_760 Phosphate regulon metal ion transporter containing CBS domains low > 87
Pseudomonas syringae pv. syringae B728a ΔmexB 0.26 Psyr_2050 ATP-binding region, ATPase-like:Histidine kinase A, N-terminal:Osmosensitive K+ channel His kinase sensor:UspA 0.12 Psyr_5034 CBS:Protein of unknown function DUF21:Transporter-associated region low > 86
Pseudomonas syringae pv. syringae B728a 0.26 Psyr_2050 ATP-binding region, ATPase-like:Histidine kinase A, N-terminal:Osmosensitive K+ channel His kinase sensor:UspA 0.12 Psyr_5034 CBS:Protein of unknown function DUF21:Transporter-associated region low > 86
Pseudomonas simiae WCS417 0.26 PS417_08300 histidine kinase 0.10 PS417_28050 hypothetical protein low > 88
Pseudomonas fluorescens SBW25 0.26 PFLU_RS08240 sensor histidine kinase KdpD 0.10 PFLU_RS29735 HlyC/CorC family transporter low > 109
Pseudomonas fluorescens SBW25-INTG 0.26 PFLU_RS08240 sensor histidine kinase KdpD 0.10 PFLU_RS29735 HlyC/CorC family transporter low > 109
Pseudomonas putida KT2440 0.25 PP_4158 sensor protein 0.11 PP_5322 putative metal ion transporter low > 96
Xanthomonas campestris pv. campestris strain 8004 0.25 Xcc-8004.4379.1 Osmosensitive K+ channel histidine kinase KdpD (EC 2.7.3.-) 0.21 Xcc-8004.3156.1 Magnesium and cobalt efflux protein CorC low > 74
Pseudomonas fluorescens FW300-N1B4 0.25 Pf1N1B4_312 Osmosensitive K+ channel histidine kinase KdpD (EC 2.7.3.-) 0.11 Pf1N1B4_2042 Phosphate regulon metal ion transporter containing CBS domains low > 87
Brevundimonas sp. GW460-12-10-14-LB2 0.24 A4249_RS15630 sensor histidine kinase KdpD 0.22 A4249_RS08175 hemolysin family protein low > 48
Acinetobacter radioresistens SK82 0.23 MPMX26_02241 Sensor protein KdpD 0.55 MPMX26_02321 hypothetical protein — —

Not shown: 7 genomes with orthologs for ECD_00652 only; 23 genomes with orthologs for ECD_04089 only