Conservation of cofitness between DZA65_RS10585 and DZA65_RS11720 in Dickeya dianthicola ME23

62 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Dickeya dianthicola ME23 1.0 DZA65_RS10585 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 1.0 DZA65_RS11720 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD 0.93 1
Dickeya dianthicola 67-19 1.00 HGI48_RS10170 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 1.00 HGI48_RS11375 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD 0.63 43
Dickeya dadantii 3937 1.00 DDA3937_RS10140 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.98 DDA3937_RS11335 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD 0.94 1
Pectobacterium carotovorum WPP14 0.92 HER17_RS11775 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.94 HER17_RS11410 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD 0.98 1
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.90 GFF1629 4-hydroxy-2-oxoglutarate aldolase (EC 4.1.3.16) @ 2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14) 0.85 GFF1327 2-deoxy-D-gluconate 3-dehydrogenase (EC 1.1.1.125) low > 78
Enterobacter asburiae PDN3 0.89 EX28DRAFT_0706 Entner-Doudoroff aldolase 0.85 EX28DRAFT_2921 2-deoxy-D-gluconate 3-dehydrogenase low > 76
Enterobacter sp. TBS_079 0.89 MPMX20_02755 KHG/KDPG aldolase 0.86 MPMX20_03715 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase low > 85
Serratia liquefaciens MT49 0.87 IAI46_14570 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.37 IAI46_17585 gluconate 5-dehydrogenase low > 86
Rahnella sp. WP5 0.86 EX31_RS16625 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.87 EX31_RS01480 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD low > 89
Escherichia coli ECOR38 0.86 HEPCGN_04750 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.86 HEPCGN_19585 kduD 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD low > 87
Escherichia coli BL21 0.86 ECD_01821 KHG/KDPG aldolase; 2-dehydro-3-deoxy-phosphogluconate/4-hydroxy-2- oxoglutarate aldolase 0.39 ECD_02618 putative SDR family oxidoreductase — —
Escherichia coli ECRC99 0.86 KEDOAH_01760 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.85 KEDOAH_08205 kduD 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD — —
Escherichia coli ECRC100 0.86 OKFHMN_26345 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.85 OKFHMN_19925 kduD 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD low > 80
Escherichia coli ECRC98 0.86 JDDGAC_00920 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.85 JDDGAC_23590 kduD 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD low > 86
Escherichia coli HS(pFamp)R (ATCC 700891) 0.86 OHPLBJKB_01879 KHG/KDPG aldolase 0.86 OHPLBJKB_00887 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase low > 73
Escherichia fergusonii Becca 0.86 EFB2_02093 KHG/KDPG aldolase 0.85 EFB2_01041 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase low > 86
Escherichia coli ECRC102 0.86 NIAGMN_01715 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.85 NIAGMN_17695 kduD 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD — —
Escherichia coli ECRC62 0.86 BNILDI_15650 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.86 BNILDI_10290 kduD 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD low > 75
Escherichia coli ECRC101 0.86 MCAODC_19060 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.85 MCAODC_10450 kduD 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD low > 87
Escherichia coli BW25113 0.86 b1850 eda keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (NCBI) 0.86 b2842 kduD 2-deoxy-D-gluconate 3-dehydrogenase (NCBI) low > 76
Escherichia coli Nissle 1917 0.86 ECOLIN_RS10305 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.85 ECOLIN_RS15950 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD — —
Escherichia coli ECOR27 0.85 NOLOHH_16855 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.86 NOLOHH_11810 kduD 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD low > 75
Pantoea sp. MT58 0.84 IAI47_08500 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.77 IAI47_11020 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD low > 76
Klebsiella michiganensis M5al 0.81 BWI76_RS18095 ketohydroxyglutarate aldolase 0.87 BWI76_RS23430 2-deoxy-D-gluconate 3-dehydrogenase — —
Erwinia tracheiphila SCR3 0.78 LU632_RS13355 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.86 LU632_RS00060 kduD 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD low > 74
Alteromonas macleodii MIT1002 0.66 MIT1002_02403 KHG/KDPG aldolase 0.52 MIT1002_03304 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase — —
Herbaspirillum seropedicae SmR1 0.52 HSERO_RS05525 ketohydroxyglutarate aldolase 0.34 HSERO_RS05480 gluconate 5-dehydrogenase — —
Ralstonia solanacearum PSI07 0.50 RPSI07_RS05475 ketohydroxyglutarate aldolase 0.34 RPSI07_RS02795 3-oxoacyl-ACP reductase — —
Pseudomonas putida KT2440 0.49 PP_1024 KHG/KDPG aldolase 0.27 PP_3073 3-hydroxybutyrate dehydrogenase — —
Variovorax sp. OAS795 0.48 ABID97_RS21295 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.30 ABID97_RS01190 SDR family oxidoreductase — —
Pseudomonas sp. S08-1 0.47 OH686_02425 4-hydroxy-2-oxoglutarate aldolase or 2-dehydro-3-deoxyphosphogluconate aldolase 0.28 OH686_00815 3-hydroxybutyrate dehydrogenase low > 80
Sphingomonas koreensis DSMZ 15582 0.47 Ga0059261_0356 Entner-Doudoroff aldolase 0.61 Ga0059261_2966 2-deoxy-D-gluconate 3-dehydrogenase — —
Sinorhizobium meliloti 1021 0.47 SMc03153 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase 0.54 SM_b21348 2-deoxy-D-gluconate 3-dehydrogenase low > 103
Ralstonia solanacearum IBSBF1503 0.47 RALBFv3_RS18160 ketohydroxyglutarate aldolase 0.28 RALBFv3_RS01840 NAD(P)-dependent oxidoreductase — —
Ralstonia solanacearum UW163 0.47 UW163_RS20970 ketohydroxyglutarate aldolase 0.28 UW163_RS15150 NAD(P)-dependent oxidoreductase — —
Variovorax sp. SCN45 0.46 GFF6512 4-hydroxy-2-oxoglutarate aldolase (EC 4.1.3.16) @ 2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14) 0.32 GFF6751 Oxidoreductase, short-chain dehydrogenase/reductase family low > 127
Ralstonia solanacearum GMI1000 0.46 RS_RS22875 ketohydroxyglutarate aldolase 0.35 RS_RS21655 3-oxoacyl-ACP reductase — —
Phaeobacter inhibens DSM 17395 0.46 PGA1_c28010 KHG/KDPG aldolase 0.33 PGA1_c27390 short-chain dehydrogenase/reductase — —
Paraburkholderia sabiae LMG 24235 0.46 QEN71_RS26915 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.61 QEN71_RS37290 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.46 GFF5496 4-hydroxy-2-oxoglutarate aldolase (EC 4.1.3.16) @ 2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14) 0.33 GFF3625 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100) — —
Ralstonia sp. UNC404CL21Col 0.45 ABZR87_RS19090 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.65 ABZR87_RS20810 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD — —
Agrobacterium fabrum C58 0.45 Atu4494 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase 0.55 Atu3141 2-deoxy-D-gluconate 3-dehydrogenase — —
Burkholderia phytofirmans PsJN 0.45 BPHYT_RS16730 2-dehydro-3-deoxyphosphogluconate aldolase 0.61 BPHYT_RS10945 2-deoxy-D-gluconate 3-dehydrogenase — —
Bosea sp. OAE506 0.45 ABIE41_RS23505 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.54 ABIE41_RS07840 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD low > 77
Paraburkholderia graminis OAS925 0.44 ABIE53_003516 2-dehydro-3-deoxyphosphogluconate aldolase/(4S)-4-hydroxy-2-oxoglutarate aldolase 0.67 ABIE53_002285 2-deoxy-D-gluconate 3-dehydrogenase — —
Pseudomonas fluorescens SBW25-INTG 0.44 PFLU_RS23715 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.29 PFLU_RS18185 SDR family oxidoreductase — —
Pseudomonas fluorescens SBW25 0.44 PFLU_RS23715 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.29 PFLU_RS18185 SDR family oxidoreductase — —
Lysobacter sp. OAE881 0.44 ABIE51_RS01605 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.61 ABIE51_RS02825 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD — —
Acidovorax sp. GW101-3H11 0.44 Ac3H11_2083 4-Hydroxy-2-oxoglutarate aldolase (EC 4.1.3.16) @ 2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14) 0.29 Ac3H11_3445 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100) — —
Paraburkholderia bryophila 376MFSha3.1 0.44 H281DRAFT_04277 2-keto-3-deoxy-phosphogluconate aldolase 0.67 H281DRAFT_01159 2-deoxy-D-gluconate 3-dehydrogenase — —
Cupriavidus basilensis FW507-4G11 0.44 RR42_RS28865 2-dehydro-3-deoxyphosphogluconate aldolase 0.29 RR42_RS21790 short-chain dehydrogenase — —
Rhizobium sp. OAE497 0.44 ABIE40_RS16720 2-dehydro-3-deoxy-phosphogluconate aldolase 0.58 ABIE40_RS25290 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD — —
Xanthomonas campestris pv. campestris strain 8004 0.41 Xcc-8004.2446.1 hypothetical protein 0.63 Xcc-8004.207.1 hypothetical protein — —
Azospirillum brasilense Sp245 0.38 AZOBR_RS29850 ketohydroxyglutarate aldolase 0.64 AZOBR_RS30220 3-ketoacyl-ACP reductase — —
Parabacteroides merdae CL09T00C40 0.20 HMPREF1078_RS05610 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.35 HMPREF1078_RS17155 gluconate 5-dehydrogenase low > 61
Bacteroides stercoris CC31F 0.19 HMPREF1181_RS15440 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.33 HMPREF1181_RS01625 gluconate 5-dehydrogenase low > 56
Brevundimonas sp. GW460-12-10-14-LB2 0.19 A4249_RS10775 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.64 A4249_RS07665 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD — —
Bacteroides ovatus ATCC 8483 0.19 BACOVA_03829 KDPG and KHG aldolase 0.32 BACOVA_00141 oxidoreductase, short chain dehydrogenase/reductase family protein 0.27 82
Phocaeicola dorei CL03T12C01 0.19 ABI39_RS15380 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.33 ABI39_RS05980 gluconate 5-dehydrogenase low > 72
Phocaeicola vulgatus CL09T03C04 0.19 HMPREF1058_RS01685 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.33 HMPREF1058_RS11050 gluconate 5-dehydrogenase 0.54 46
Caulobacter crescentus NA1000 Δfur 0.18 CCNA_01562 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxyphosphogluconate aldolase 0.59 CCNA_01559 2-deoxy-D-gluconate 3-dehydrogenase low > 67
Caulobacter crescentus NA1000 0.18 CCNA_01562 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxyphosphogluconate aldolase 0.59 CCNA_01559 2-deoxy-D-gluconate 3-dehydrogenase low > 66
Pedobacter sp. GW460-11-11-14-LB5 0.16 CA265_RS19860 2-dehydro-3-deoxy-phosphogluconate aldolase (EC 4.1.2.14) (from data) 0.50 CA265_RS00760 2-deoxy-D-gluconate 3-dehydrogenase low > 88

Not shown: 24 genomes with orthologs for DZA65_RS10585 only; 3 genomes with orthologs for DZA65_RS11720 only