Conservation of cofitness between CSW01_06870 and CSW01_08580 in Vibrio cholerae E7946 ATCC 55056

66 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_06870 7-carboxy-7-deazaguanine synthase QueE 1.0 CSW01_08580 HTH-type transcriptional regulator MetR 0.41 12
Dickeya dadantii 3937 0.60 DDA3937_RS16970 7-carboxy-7-deazaguanine synthase QueE 0.57 DDA3937_RS20385 HTH-type transcriptional regulator MetR low > 74
Shewanella oneidensis MR-1 0.60 SO2501 radical activating enzyme (NCBI ptt file) 0.41 SO0817 metR transcriptional activator protein MetR (NCBI ptt file) low > 76
Pectobacterium carotovorum WPP14 0.59 HER17_RS04200 7-carboxy-7-deazaguanine synthase QueE 0.57 HER17_RS20690 HTH-type transcriptional regulator MetR low > 75
Shewanella sp. ANA-3 0.59 Shewana3_2163 radical activating enzyme (RefSeq) 0.41 Shewana3_3470 LysR family transcriptional regulator (RefSeq) low > 73
Rahnella sp. WP5 0.58 EX31_RS07920 7-carboxy-7-deazaguanine synthase QueE 0.56 EX31_RS25370 HTH-type transcriptional regulator MetR low > 89
Serratia liquefaciens MT49 0.58 IAI46_03675 7-carboxy-7-deazaguanine synthase QueE 0.58 IAI46_01030 HTH-type transcriptional regulator MetR low > 87
Erwinia amylovora T8 0.57 OLJFJH_09270 7-carboxy-7-deazaguanine synthase QueE 0.57 OLJFJH_06475 HTH-type transcriptional regulator MetR low > 58
Erwinia tracheiphila SCR3 0.57 LU632_RS06390 queE 7-carboxy-7-deazaguanine synthase QueE 0.57 LU632_RS24035 metR HTH-type transcriptional regulator MetR low > 73
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.57 GFF4831 Queuosine Biosynthesis QueE Radical SAM 0.57 GFF253 Transcriptional activator MetR low > 78
Escherichia coli ECOR27 0.57 NOLOHH_12170 queE 7-carboxy-7-deazaguanine synthase QueE 0.57 NOLOHH_06460 metR HTH-type transcriptional regulator MetR low > 76
Escherichia coli ECRC98 0.57 JDDGAC_23965 queE 7-carboxy-7-deazaguanine synthase QueE 0.57 JDDGAC_17955 metR HTH-type transcriptional regulator MetR low > 87
Escherichia coli ECRC99 0.57 KEDOAH_07830 queE 7-carboxy-7-deazaguanine synthase QueE 0.57 KEDOAH_13820 metR HTH-type transcriptional regulator MetR — —
Escherichia coli ECRC62 0.57 BNILDI_10675 queE 7-carboxy-7-deazaguanine synthase QueE 0.57 BNILDI_05070 metR HTH-type transcriptional regulator MetR low > 75
Escherichia coli ECRC101 0.57 MCAODC_10825 queE 7-carboxy-7-deazaguanine synthase QueE 0.57 MCAODC_04835 metR HTH-type transcriptional regulator MetR low > 87
Escherichia coli BL21 0.57 ECD_02622 7-carboxy-7-deazaguanine synthase; queosine biosynthesis 0.57 ECD_03707 methionine biosynthesis regulon transcriptional regulator low > 61
Escherichia coli ECRC102 0.57 NIAGMN_18070 queE 7-carboxy-7-deazaguanine synthase QueE 0.57 NIAGMN_12085 metR HTH-type transcriptional regulator MetR low > 80
Escherichia fergusonii Becca 0.57 EFB2_01141 7-carboxy-7-deazaguanine synthase 0.57 EFB2_04809 HTH-type transcriptional regulator MetR low > 86
Erwinia tracheiphila HP pepo 2.2 0.57 IJEDHG_17410 queE 7-carboxy-7-deazaguanine synthase QueE 0.56 IJEDHG_08680 metR HTH-type transcriptional regulator MetR low > 61
Escherichia coli BW25113 0.57 b2777 ygcF hypothetical protein (NCBI) 0.57 b3828 metR DNA-binding transcriptional activator, homocysteine-binding (NCBI) low > 76
Escherichia coli HS(pFamp)R (ATCC 700891) 0.57 OHPLBJKB_00957 7-carboxy-7-deazaguanine synthase 0.57 OHPLBJKB_04223 HTH-type transcriptional regulator MetR low > 74
Escherichia coli ECOR38 0.57 HEPCGN_19205 queE 7-carboxy-7-deazaguanine synthase QueE 0.57 HEPCGN_13030 metR HTH-type transcriptional regulator MetR low > 88
Escherichia coli Nissle 1917 0.57 ECOLIN_RS15475 7-carboxy-7-deazaguanine synthase QueE 0.57 ECOLIN_RS30005 HTH-type transcriptional regulator MetR — —
Escherichia coli ECRC100 0.57 OKFHMN_20300 queE 7-carboxy-7-deazaguanine synthase QueE 0.57 OKFHMN_14330 metR HTH-type transcriptional regulator MetR low > 79
Shewanella loihica PV-4 0.56 Shew_2061 radical SAM domain-containing protein (RefSeq) 0.41 Shew_2987 LysR family transcriptional regulator (RefSeq) 0.38 49
Dickeya dianthicola 67-19 0.56 HGI48_RS17035 7-carboxy-7-deazaguanine synthase QueE 0.57 HGI48_RS00815 HTH-type transcriptional regulator MetR low > 71
Enterobacter sp. TBS_079 0.56 MPMX20_03645 7-carboxy-7-deazaguanine synthase 0.57 MPMX20_04452 HTH-type transcriptional regulator MetR low > 85
Dickeya dianthicola ME23 0.56 DZA65_RS18110 7-carboxy-7-deazaguanine synthase QueE 0.57 DZA65_RS00870 HTH-type transcriptional regulator MetR low > 75
Klebsiella michiganensis M5al 0.56 BWI76_RS22780 7-carboxy-7-deazaguanine synthase QueE 0.54 BWI76_RS01275 LysR family transcriptional regulator low > 92
Enterobacter asburiae PDN3 0.56 EX28DRAFT_2855 putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE 0.56 EX28DRAFT_4493 Transcriptional regulator low > 76
Pantoea sp. MT58 0.56 IAI47_04140 7-carboxy-7-deazaguanine synthase QueE 0.55 IAI47_18315 HTH-type transcriptional regulator MetR low > 76
Klebsiella pneumoniae MKP103 0.56 KDGMDA_03310 7-carboxy-7-deazaguanine synthase QueE 0.54 KDGMDA_09770 HTH-type transcriptional regulator MetR low > 95
Pantoea agglomerans CFBP13505 P0401 0.55 PagCFBP13505_RS16825 7-carboxy-7-deazaguanine synthase QueE 0.55 PagCFBP13505_RS15295 HTH-type transcriptional regulator MetR low > 74
Shewanella amazonensis SB2B 0.55 Sama_1825 radical activating enzyme (RefSeq) 0.41 Sama_2628 transcriptional activator protein MetR (RefSeq) low > 62
Alteromonas macleodii MIT1002 0.51 MIT1002_01264 7-carboxy-7-deazaguanine synthase 0.31 MIT1002_01119 HTH-type transcriptional regulator GltC low > 70
Paraburkholderia sabiae LMG 24235 0.42 QEN71_RS41925 7-carboxy-7-deazaguanine synthase QueE 0.37 QEN71_RS19730 LysR family transcriptional regulator low > 153
Mucilaginibacter yixingensis YX-36 DSM 26809 0.22 ABZR88_RS09380 7-carboxy-7-deazaguanine synthase QueE 0.26 ABZR88_RS03450 LysR family transcriptional regulator low > 71
Herbaspirillum seropedicae SmR1 0.17 HSERO_RS11035 7-cyano-7-deazaguanine reductase 0.38 HSERO_RS22770 LysR family transcriptional regulator low > 78
Variovorax sp. SCN45 0.16 GFF2577 7-carboxy-7-deazaguanine synthase (EC 4.3.99.3) 0.38 GFF796 Transcriptional activator MetR — —
Burkholderia phytofirmans PsJN 0.16 BPHYT_RS01505 7-cyano-7-deazaguanine reductase 0.40 BPHYT_RS26650 LysR family transcriptional regulator — —
Variovorax sp. OAS795 0.15 ABID97_RS07425 7-carboxy-7-deazaguanine synthase 0.40 ABID97_RS19400 LysR family transcriptional regulator — —
Azospirillum brasilense Sp245 0.15 AZOBR_RS04155 radical SAM protein 0.33 AZOBR_RS24270 LysR family transcriptional regulator low > 97
Ralstonia sp. UNC404CL21Col 0.15 ABZR87_RS12145 7-carboxy-7-deazaguanine synthase 0.37 ABZR87_RS20875 LysR family transcriptional regulator low > 80
Ralstonia solanacearum PSI07 0.15 RPSI07_RS16890 7-carboxy-7-deazaguanine synthase 0.38 RPSI07_RS02550 LysR family transcriptional regulator — —
Ralstonia solanacearum GMI1000 0.14 RS_RS07295 7-carboxy-7-deazaguanine synthase 0.37 RS_RS20365 LysR family transcriptional regulator low > 80
Acidovorax sp. GW101-3H11 0.14 Ac3H11_3825 Queuosine Biosynthesis QueE Radical SAM 0.41 Ac3H11_2344 Transcriptional activator MetR — —
Pseudomonas sp. RS175 0.14 PFR28_03404 7-carboxy-7-deazaguanine synthase 0.51 PFR28_03478 HTH-type transcriptional regulator MetR low > 88
Pseudomonas sp. DMC3 0.14 GFF5176 7-carboxy-7-deazaguanine synthase 0.50 GFF5120 HTH-type transcriptional regulator MetR low > 89
Ralstonia solanacearum IBSBF1503 0.13 RALBFv3_RS00615 7-carboxy-7-deazaguanine synthase 0.38 RALBFv3_RS20315 LysR family transcriptional regulator — —
Ralstonia solanacearum UW163 0.13 UW163_RS13945 7-carboxy-7-deazaguanine synthase 0.38 UW163_RS18860 LysR family transcriptional regulator — —
Cupriavidus basilensis FW507-4G11 0.13 RR42_RS11390 7-cyano-7-deazaguanine reductase 0.39 RR42_RS30655 LysR family transcriptional regulator — —
Pseudomonas lactucae CFBP13502 0.13 GEMAOFIL_04633 7-carboxy-7-deazaguanine synthase 0.50 GEMAOFIL_01280 HTH-type transcriptional regulator MetR low > 96
Pseudomonas simiae WCS417 0.13 PS417_22405 7-carboxy-7-deazaguanine synthase 0.49 PS417_05455 XRE family transcriptional regulator low > 88
Pseudomonas orientalis W4I3 0.13 QF045_RS24570 7-carboxy-7-deazaguanine synthase QueE 0.50 QF045_RS08390 transcriptional regulator MetR low > 93
Pseudomonas fluorescens SBW25 0.13 PFLU_RS24045 7-carboxy-7-deazaguanine synthase QueE 0.50 PFLU_RS05540 LysR family transcriptional regulator low > 109
Pseudomonas fluorescens SBW25-INTG 0.13 PFLU_RS24045 7-carboxy-7-deazaguanine synthase QueE 0.50 PFLU_RS05540 LysR family transcriptional regulator low > 109
Pseudomonas fluorescens FW300-N2C3 0.13 AO356_18065 7-carboxy-7-deazaguanine synthase 0.50 AO356_17735 XRE family transcriptional regulator low > 104
Pseudomonas fluorescens FW300-N2E2 0.13 Pf6N2E2_5545 Queuosine Biosynthesis QueE Radical SAM 0.50 Pf6N2E2_5471 Transcriptional activator MetR low > 103
Pseudomonas sp. S08-1 0.12 OH686_19175 7-carboxy-7-deazaguanine synthase 0.50 OH686_20465 Transcriptional activator MetR low > 80
Pseudomonas putida KT2440 0.12 PP_1225 7-carboxy-7-deazaguanine synthase 0.51 PP_1063 DNA-binding transcriptional regulator, homocysteine-binding low > 96
Pseudomonas aeruginosa PA14 0.12 IKLFDK_04415 7-carboxy-7-deazaguanine synthase QueE 0.51 IKLFDK_18315 transcriptional regulator MetR — —
Pseudomonas sp. BP01 0.12 JOY50_RS01775 queE 7-carboxy-7-deazaguanine synthase QueE 0.50 JOY50_RS14810 metR transcriptional regulator MetR low > 84
Pseudomonas fluorescens GW456-L13 0.12 PfGW456L13_1861 Queuosine Biosynthesis QueE Radical SAM 0.49 PfGW456L13_4778 Transcriptional activator MetR low > 87
Pseudomonas fluorescens FW300-N1B4 0.12 Pf1N1B4_629 Queuosine Biosynthesis QueE Radical SAM 0.49 Pf1N1B4_784 Transcriptional activator MetR low > 87
Pseudomonas aeruginosa MRSN321 0.12 DY961_RS07555 queE;go_function=4 7-carboxy-7-deazaguanine synthase QueE 0.51 DY961_RS15050 metR;inference=COORDINATES transcriptional regulator MetR low > 100
Pseudomonas aeruginosa PUPa3 0.12 DQ20_RS45235 queE;go_function=4 7-carboxy-7-deazaguanine synthase QueE 0.51 DQ20_RS42085 metR;inference=COORDINATES transcriptional regulator MetR low > 101
Pseudomonas segetis P6 0.12 MPMX49_01693 7-carboxy-7-deazaguanine synthase 0.51 MPMX49_01426 HTH-type transcriptional regulator MetR low > 75

Not shown: 32 genomes with orthologs for CSW01_06870 only; 16 genomes with orthologs for CSW01_08580 only