Conservation of cofitness between CSW01_11300 and CSW01_07075 in Vibrio cholerae E7946 ATCC 55056

60 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_11300 copper-exporting P-type ATPase A 1.0 CSW01_07075 MFS transporter 0.63 19
Pantoea sp. MT58 0.45 IAI47_14400 copper-exporting P-type ATPase CopA 0.38 IAI47_04495 multidrug efflux MFS transporter permease subunit EmrB low > 76
Serratia liquefaciens MT49 0.44 IAI46_05310 copper-exporting P-type ATPase CopA 0.36 IAI46_20005 multidrug efflux MFS transporter permease subunit EmrB low > 86
Pectobacterium carotovorum WPP14 0.44 HER17_RS15625 copper-exporting P-type ATPase CopA 0.37 HER17_RS04460 multidrug efflux MFS transporter permease subunit EmrB low > 75
Enterobacter asburiae PDN3 0.44 EX28DRAFT_2474 copper-(or silver)-translocating P-type ATPase 0.53 EX28DRAFT_2615 drug resistance transporter, EmrB/QacA subfamily low > 76
Klebsiella michiganensis M5al 0.43 BWI76_RS06905 Cu+ exporting ATPase 0.39 BWI76_RS22100 multidrug effux MFS transporter subunit EmrB low > 92
Enterobacter sp. TBS_079 0.43 MPMX20_01084 Copper-exporting P-type ATPase 0.39 MPMX20_03564 Multidrug export protein EmrB low > 85
Dickeya dianthicola ME23 0.42 DZA65_RS06225 copper-exporting P-type ATPase CopA 0.38 DZA65_RS17910 multidrug efflux MFS transporter permease subunit EmrB low > 75
Escherichia coli ECOR38 0.42 HEPCGN_06710 copA copper-exporting P-type ATPase CopA 0.37 HEPCGN_19970 emrB multidrug efflux MFS transporter permease subunit EmrB low > 87
Escherichia fergusonii Becca 0.42 EFB2_03575 Copper-exporting P-type ATPase 0.37 EFB2_01242 Multidrug export protein EmrB low > 86
Escherichia coli ECRC100 0.42 OKFHMN_08075 copA copper-exporting P-type ATPase CopA 0.37 OKFHMN_20775 emrB multidrug efflux MFS transporter permease subunit EmrB low > 80
Escherichia coli ECRC102 0.42 NIAGMN_06125 copA copper-exporting P-type ATPase CopA 0.37 NIAGMN_18545 emrB multidrug efflux MFS transporter permease subunit EmrB
Escherichia coli ECRC98 0.42 JDDGAC_11720 copA copper-exporting P-type ATPase CopA 0.37 JDDGAC_24440 emrB multidrug efflux MFS transporter permease subunit EmrB low > 86
Escherichia coli ECRC101 0.42 MCAODC_27295 copA copper-exporting P-type ATPase CopA 0.37 MCAODC_11300 emrB multidrug efflux MFS transporter permease subunit EmrB low > 87
Escherichia coli ECRC99 0.42 KEDOAH_19895 copA copper-exporting P-type ATPase CopA 0.37 KEDOAH_07360 emrB multidrug efflux MFS transporter permease subunit EmrB
Dickeya dianthicola 67-19 0.42 HGI48_RS05890 copper-exporting P-type ATPase CopA 0.38 HGI48_RS16835 multidrug efflux MFS transporter permease subunit EmrB low > 71
Dickeya dadantii 3937 0.42 DDA3937_RS05845 copper-exporting P-type ATPase CopA 0.37 DDA3937_RS16765 multidrug efflux MFS transporter permease subunit EmrB low > 74
Escherichia coli ECOR27 0.42 NOLOHH_01015 copA copper-exporting P-type ATPase CopA 0.37 NOLOHH_12615 emrB multidrug efflux MFS transporter permease subunit EmrB low > 75
Escherichia coli Nissle 1917 0.42 ECOLIN_RS02865 copper-exporting P-type ATPase CopA 0.37 ECOLIN_RS14970 multidrug efflux MFS transporter permease subunit EmrB low > 55
Escherichia coli ECRC62 0.42 BNILDI_22435 copA copper-exporting P-type ATPase CopA 0.37 BNILDI_11175 emrB multidrug efflux MFS transporter permease subunit EmrB low > 75
Escherichia coli HS(pFamp)R (ATCC 700891) 0.42 OHPLBJKB_03190 Copper-exporting P-type ATPase 0.37 OHPLBJKB_01047 Multidrug export protein EmrB low > 73
Escherichia coli BL21 0.42 ECD_00435 copper transporter 0.37 ECD_02541 multidrug efflux system protein low > 61
Escherichia coli BW25113 0.42 b0484 copA copper transporter (NCBI) 0.37 b2686 emrB multidrug efflux system protein (NCBI) low > 76
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.42 GFF4404 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) 0.38 GFF1593 Multidrug resistance protein B low > 78
Rahnella sp. WP5 0.42 EX31_RS22575 copper-exporting P-type ATPase CopA 0.37 EX31_RS13660 multidrug efflux MFS transporter permease subunit EmrB low > 89
Erwinia tracheiphila SCR3 0.41 LU632_RS15300 copA copper-exporting P-type ATPase CopA 0.23 LU632_RS09490 DHA2 family efflux MFS transporter permease subunit low > 74
Shewanella loihica PV-4 0.39 Shew_3818 copper-translocating P-type ATPase (RefSeq) 0.21 Shew_3405 EmrB/QacA family drug resistance transporter (RefSeq) low > 60
Shewanella oneidensis MR-1 0.39 SO1689 cation transport ATPase, E1-E2 family (NCBI ptt file) 0.21 SO0525 drug resistance transporter, EmrB/QacA family protein (NCBI ptt file) low > 76
Acinetobacter radioresistens SK82 0.33 MPMX26_01948 Copper-transporting P-type ATPase 0.47 MPMX26_02394 Multidrug export protein EmrB low > 36
Agrobacterium fabrum C58 0.32 Atu1195 heavy-metal transporting P-type ATPase 0.21 Atu4479 MFS permease low > 89
Castellaniella sp019104865 MT123 0.31 ABCV34_RS04200 heavy metal translocating P-type ATPase 0.40 ABCV34_RS05950 DHA2 family efflux MFS transporter permease subunit low > 48
Echinicola vietnamensis KMM 6221, DSM 17526 0.31 Echvi_4125 copper-(or silver)-translocating P-type ATPase 0.11 Echvi_4503 drug resistance transporter, EmrB/QacA subfamily low > 79
Sinorhizobium meliloti 1021 0.31 SM_b21578 copper-transporting P-type ATPase 0.17 SMc03167 multidrug efflux system protein low > 103
Bosea sp. OAE506 0.30 ABIE41_RS14220 heavy metal translocating P-type ATPase 0.20 ABIE41_RS08465 DHA2 family efflux MFS transporter permease subunit low > 77
Acidovorax sp. GW101-3H11 0.28 Ac3H11_4218 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) 0.40 Ac3H11_2352 Inner membrane component of tripartite multidrug resistance system low > 79
Pseudomonas fluorescens FW300-N1B4 0.28 Pf1N1B4_1262 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) 0.37 Pf1N1B4_4002 Inner membrane component of tripartite multidrug resistance system low > 87
Pseudomonas fluorescens FW300-N2E3 0.28 AO353_06155 copper-transporting ATPase 0.37 AO353_27840 multidrug resistance protein B low > 101
Pseudomonas fluorescens FW300-N2C3 0.28 AO356_08065 copper-transporting ATPase 0.38 AO356_01025 multidrug resistance protein B low > 104
Pseudomonas fluorescens GW456-L13 0.28 PfGW456L13_24 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) 0.37 PfGW456L13_2606 Inner membrane component of tripartite multidrug resistance system low > 87
Ralstonia sp. UNC404CL21Col 0.28 ABZR87_RS04235 heavy metal translocating P-type ATPase 0.41 ABZR87_RS11225 DHA2 family efflux MFS transporter permease subunit low > 80
Pseudomonas syringae pv. syringae B728a ΔmexB 0.28 Psyr_0654 Copper-translocating P-type ATPase:Heavy metal translocating P-type ATPase 0.37 Psyr_1731 Drug resistance transporter EmrB/QacA subfamily low > 86
Pseudomonas syringae pv. syringae B728a 0.28 Psyr_0654 Copper-translocating P-type ATPase:Heavy metal translocating P-type ATPase 0.37 Psyr_1731 Drug resistance transporter EmrB/QacA subfamily low > 86
Pseudomonas sp. RS175 0.28 PFR28_05244 Copper-exporting P-type ATPase 0.37 PFR28_02747 Multidrug export protein EmrB low > 88
Lysobacter sp. OAE881 0.27 ABIE51_RS09555 heavy metal translocating P-type ATPase 0.39 ABIE51_RS07705 DHA2 family efflux MFS transporter permease subunit low > 62
Pseudomonas simiae WCS417 0.27 PS417_03160 metal ABC transporter ATPase 0.38 PS417_16910 multidrug resistance protein B low > 88
Desulfovibrio vulgaris Miyazaki F 0.27 DvMF_3170 heavy metal translocating P-type ATPase (RefSeq) 0.26 DvMF_1099 drug resistance transporter, EmrB/QacA subfamily (RefSeq) low > 51
Burkholderia phytofirmans PsJN 0.27 BPHYT_RS34125 heavy metal translocating P-type ATPase 0.42 BPHYT_RS19670 DSBA oxidoreductase low > 109
Pseudomonas putida KT2440 0.27 PP_0586 cadmium translocating P-type ATPase 0.38 PP_3548 multidrug efflux transport system - permease subunit low > 96
Pseudomonas sp. S08-1 0.27 OH686_07395 copper-translocating P-type ATPase 0.21 OH686_04570 Inner-membrane proton/drug antiporter (MSF type) of tripartite multidrug efflux system low > 80
Paraburkholderia sabiae LMG 24235 0.27 QEN71_RS17330 heavy metal translocating P-type ATPase 0.38 QEN71_RS23085 DHA2 family efflux MFS transporter permease subunit low > 153
Magnetospirillum magneticum AMB-1 0.27 AMB_RS09145 copper-translocating P-type ATPase 0.20 AMB_RS20240 MFS transporter
Pseudomonas fluorescens SBW25 0.27 PFLU_RS03240 copper-translocating P-type ATPase 0.38 PFLU_RS18895 DHA2 family efflux MFS transporter permease subunit low > 109
Pseudomonas fluorescens SBW25-INTG 0.27 PFLU_RS03240 copper-translocating P-type ATPase 0.38 PFLU_RS18895 DHA2 family efflux MFS transporter permease subunit low > 109
Paraburkholderia bryophila 376MFSha3.1 0.26 H281DRAFT_03512 Cu+-exporting ATPase 0.41 H281DRAFT_02341 MFS transporter, DHA2 family, multidrug resistance protein low > 103
Paraburkholderia graminis OAS925 0.26 ABIE53_004745 Cu+-exporting ATPase 0.42 ABIE53_000311 DHA2 family multidrug resistance protein low > 113
Ralstonia solanacearum GMI1000 0.26 RS_RS16775 copper-translocating P-type ATPase 0.55 RS_RS09355 MFS transporter low > 80
Ralstonia solanacearum PSI07 0.26 RPSI07_RS08310 copper-translocating P-type ATPase 0.40 RPSI07_RS17660 MFS transporter low > 81
Herbaspirillum seropedicae SmR1 0.25 HSERO_RS08020 heavy metal translocating P-type ATPase 0.64 HSERO_RS16355 DSBA oxidoreductase low > 78
Rhodospirillum rubrum S1H 0.24 Rru_A1894 heavy metal translocating P-type ATPase (NCBI) 0.37 Rru_A0858 Drug resistance transporter EmrB/QacA subfamily (NCBI) low > 58
Variovorax sp. OAS795 0.23 ABID97_RS02825 heavy metal translocating P-type ATPase 0.42 ABID97_RS20390 DHA2 family efflux MFS transporter permease subunit low > 91
Mucilaginibacter yixingensis YX-36 DSM 26809 0.21 ABZR88_RS09650 cation-translocating P-type ATPase 0.25 ABZR88_RS20975 DHA2 family efflux MFS transporter permease subunit low > 71

Not shown: 11 genomes with orthologs for CSW01_11300 only; 26 genomes with orthologs for CSW01_07075 only