| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
|---|
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_13675 | | bifunctional GTP diphosphokinase/guanosine-3',5'-bis(diphosphate) 3'-diphosphatase | 1.0 | CSW01_06380 | | GTP cyclohydrolase II | 0.69 | 11 |
| Klebsiella pneumoniae MRSN742743 | 0.76 | GJGHJB_00116 | spoT | bifunctional GTP diphosphokinase/guanosine-3' 5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.36 | GJGHJB_02928 | ribA | GTP cyclohydrolase-2 | — | — |
| Klebsiella michiganensis M5al | 0.76 | BWI76_RS27430 | | (p)ppGpp synthetase | 0.36 | BWI76_RS11945 | | GTP cyclohydrolase II | — | — |
| Klebsiella pneumoniae MKP103 | 0.76 | KDGMDA_08125 | | bifunctional GTP diphosphokinase/guanosine-3' 5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.36 | KDGMDA_19635 | | GTP cyclohydrolase-2 | — | — |
| Escherichia fergusonii Becca | 0.76 | EFB2_00138 | | Bifunctional (p)ppGpp synthase/hydrolase SpoT | 0.37 | EFB2_02648 | | GTP cyclohydrolase-2 | — | — |
| Escherichia coli Nissle 1917 | 0.76 | ECOLIN_RS20790 | | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.37 | ECOLIN_RS07710 | | GTP cyclohydrolase II | — | — |
| Escherichia coli BW25113 | 0.76 | b3650 | spoT | bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (NCBI) | 0.37 | b1277 | ribA | GTP cyclohydrolase II protein (NCBI) | — | — |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.76 | OHPLBJKB_00051 | | Bifunctional (p)ppGpp synthase/hydrolase SpoT | 0.37 | OHPLBJKB_02405 | | GTP cyclohydrolase-2 | — | — |
| Escherichia coli ECOR38 | 0.76 | HEPCGN_14375 | spoT | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.37 | HEPCGN_25630 | ribA | GTP cyclohydrolase-2 | — | — |
| Escherichia coli ECRC100 | 0.76 | OKFHMN_15555 | spoT | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.37 | OKFHMN_02570 | ribA | GTP cyclohydrolase-2 | — | — |
| Escherichia coli ECRC98 | 0.76 | JDDGAC_19180 | spoT | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.37 | JDDGAC_05115 | ribA | GTP cyclohydrolase-2 | — | — |
| Escherichia coli ECRC101 | 0.76 | MCAODC_06065 | spoT | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.37 | MCAODC_15695 | ribA | GTP cyclohydrolase-2 | — | — |
| Escherichia coli ECRC99 | 0.76 | KEDOAH_12590 | spoT | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.37 | KEDOAH_26195 | ribA | GTP cyclohydrolase-2 | — | — |
| Escherichia coli ECOR27 | 0.76 | NOLOHH_07435 | spoT | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.37 | NOLOHH_20235 | ribA | GTP cyclohydrolase-2 | — | — |
| Escherichia coli ECRC102 | 0.76 | NIAGMN_13315 | spoT | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.37 | NIAGMN_26740 | ribA | GTP cyclohydrolase-2 | — | — |
| Escherichia coli ECRC62 | 0.76 | BNILDI_04080 | spoT | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.37 | BNILDI_18385 | ribA | GTP cyclohydrolase-2 | — | — |
| Escherichia coli BL21 | 0.75 | ECD_03507 | | bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.37 | ECD_01254 | | GTP cyclohydrolase II | — | — |
| Enterobacter asburiae PDN3 | 0.75 | EX28DRAFT_3899 | | (p)ppGpp synthetase, RelA/SpoT family | 0.36 | EX28DRAFT_0950 | | GTP cyclohydrolase II | — | — |
| Enterobacter sp. TBS_079 | 0.75 | MPMX20_00086 | | Bifunctional (p)ppGpp synthase/hydrolase SpoT | 0.36 | MPMX20_02498 | | GTP cyclohydrolase-2 | — | — |
| Pantoea agglomerans CFBP13505 P0401 | 0.75 | PagCFBP13516_RS00495 | spoT | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.35 | PagCFBP13516_RS09390 | ribA | GTP cyclohydrolase II | — | — |
| Rahnella sp. WP5 | 0.75 | EX31_RS15810 | | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.36 | EX31_RS09880 | | GTP cyclohydrolase II | — | — |
| Erwinia tracheiphila SCR3 | 0.75 | LU632_RS22200 | spoT | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.37 | LU632_RS12530 | ribA | GTP cyclohydrolase II | — | — |
| Dickeya dianthicola ME23 | 0.75 | DZA65_RS22150 | | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.35 | DZA65_RS13050 | | GTP cyclohydrolase II | — | — |
| Dickeya dianthicola 67-19 | 0.75 | HGI48_RS21180 | | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.35 | HGI48_RS12600 | | GTP cyclohydrolase II | — | — |
| Serratia liquefaciens MT49 | 0.75 | IAI46_24895 | | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.35 | IAI46_13945 | | GTP cyclohydrolase II | — | — |
| Erwinia amylovora T8 | 0.75 | OLJFJH_05560 | | bifunctional GTP diphosphokinase/guanosine-3' 5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.35 | OLJFJH_13550 | | GTP cyclohydrolase II | — | — |
| Pantoea sp. MT58 | 0.75 | IAI47_00510 | | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.35 | IAI47_09255 | | GTP cyclohydrolase II | — | — |
| Erwinia tracheiphila HP pepo 2.2 | 0.75 | IJEDHG_08355 | spoT | bifunctional GTP diphosphokinase/guanosine-3' 5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.37 | IJEDHG_23750 | ribA | GTP cyclohydrolase II | — | — |
| Pectobacterium carotovorum WPP14 | 0.74 | HER17_RS21385 | | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.35 | HER17_RS09325 | | GTP cyclohydrolase II | — | — |
| Dickeya dadantii 3937 | 0.74 | DDA3937_RS00180 | | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.47 | DDA3937_RS21535 | | GTP cyclohydrolase II | — | — |
| Shewanella oneidensis MR-1 | 0.71 | SO0359 | spoT | guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (NCBI ptt file) | 0.37 | SO2831 | ribA | GTP cyclohydrolase II (NCBI ptt file) | — | — |
| Shewanella sp. ANA-3 | 0.71 | Shewana3_3812 | | bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (RefSeq) | 0.37 | Shewana3_2600 | ribA | GTP cyclohydrolase II (RefSeq) | — | — |
| Shewanella amazonensis SB2B | 0.71 | Sama_0264 | | bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (RefSeq) | 0.37 | Sama_1277 | ribA | GTP cyclohydrolase II (RefSeq) | — | — |
| Shewanella loihica PV-4 | 0.70 | Shew_3499 | | bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (RefSeq) | 0.37 | Shew_2446 | | GTP cyclohydrolase II (RefSeq) | — | — |
| Alteromonas macleodii MIT1002 | 0.61 | MIT1002_00108 | | Bifunctional (p)ppGpp synthase/hydrolase SpoT | 0.34 | MIT1002_00144 | | GTP cyclohydrolase-2 | — | — |
| Pseudomonas segetis P6 | 0.55 | ACVTMO_RS00180 | spoT | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.35 | ACVTMO_RS04950 | ribA | GTP cyclohydrolase II | — | — |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.55 | Psyr_0209 | | RelA/SpoT protein | 0.33 | Psyr_4456 | | GTP cyclohydrolase II | — | — |
| Pseudomonas syringae pv. syringae B728a | 0.55 | Psyr_0209 | | RelA/SpoT protein | 0.33 | Psyr_4456 | | GTP cyclohydrolase II | — | — |
| Pseudomonas aeruginosa MRSN321 | 0.54 | PFGADD_05589 | spoT | bifunctional GTP diphosphokinase/guanosine-3' 5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.35 | PFGADD_00910 | ribA | GTP cyclohydrolase-2 | — | — |
| Pseudomonas aeruginosa PUPa3 | 0.54 | NPBIFN_05665 | spoT | bifunctional GTP diphosphokinase/guanosine-3' 5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.35 | NPBIFN_00915 | ribA | GTP cyclohydrolase-2 | — | — |
| Pseudomonas aeruginosa PA14 | 0.54 | IKLFDK_26765 | | bifunctional GTP diphosphokinase/guanosine-3' 5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.35 | IKLFDK_20865 | | GTP cyclohydrolase-2 | — | — |
| Pseudomonas sp. S08-1 | 0.54 | OH686_13550 | | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase / GTP pyrophosphokinase , (p)ppGpp synthetase II | 0.34 | OH686_15740 | | GTP cyclohydrolase II | — | — |
| Pseudomonas sp. RS175 | 0.54 | PFR28_04424 | | Bifunctional (p)ppGpp synthase/hydrolase SpoT | 0.35 | PFR28_03941 | | Riboflavin biosynthesis protein | — | — |
| Pseudomonas fluorescens FW300-N2E2 | 0.54 | Pf6N2E2_4361 | | GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) | 0.35 | Pf6N2E2_4927 | | GTP cyclohydrolase II (EC 3.5.4.25) | — | — |
| Pseudomonas sp. BP01 | 0.54 | JOY50_RS08985 | spoT | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.33 | JOY50_RS20085 | ribA | GTP cyclohydrolase II | — | — |
| Pseudomonas putida KT2440 | 0.54 | PP_5302 | | bifunctional (p)ppGpp synthase/hydrolase | 0.33 | PP_0522 | | GTP cyclohydrolase-2 | — | — |
| Pseudomonas fluorescens FW300-N2C3 | 0.54 | AO356_12480 | | (p)ppGpp synthetase | 0.35 | AO356_14970 | | GTP cyclohydrolase | — | — |
| Pseudomonas sp. DMC3 | 0.54 | GFF419 | | Bifunctional (p)ppGpp synthase/hydrolase SpoT | 0.34 | GFF3835 | | Riboflavin biosynthesis protein | — | — |
| Pseudomonas protegens RBAN4 | 0.54 | FABNJH_30585 | spoT | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.45 | FABNJH_05360 | ribA | GTP cyclohydrolase-2 | — | — |
| Pseudomonas fluorescens GW456-L13 | 0.54 | PfGW456L13_780 | | GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) | 0.34 | PfGW456L13_1321 | | GTP cyclohydrolase II (EC 3.5.4.25) | — | — |
| Pseudomonas fluorescens FW300-N1B4 | 0.54 | Pf1N1B4_2113 | | GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) | 0.34 | Pf1N1B4_2657 | | GTP cyclohydrolase II (EC 3.5.4.25) | — | — |
| Pseudomonas fluorescens FW300-N2E3 | 0.54 | AO353_09280 | | (p)ppGpp synthetase | 0.35 | AO353_06675 | | GTP cyclohydrolase | — | — |
| Pseudomonas sp. SVBP6 | 0.54 | COO64_RS01555 | spoT | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.41 | COO64_RS10760 | ribA | GTP cyclohydrolase II RibA | — | — |
| Pseudomonas orientalis W4I3 | 0.53 | QF045_RS02185 | | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.35 | QF045_RS27195 | | GTP cyclohydrolase II | — | — |
| Pseudomonas stutzeri RCH2 | 0.53 | Psest_3817 | | (p)ppGpp synthetase, RelA/SpoT family | 0.34 | Psest_3544 | | GTP cyclohydrolase II | — | — |
| Pseudomonas simiae WCS417 | 0.53 | PS417_27830 | | (p)ppGpp synthetase | 0.34 | PS417_25230 | | GTP cyclohydrolase | — | — |
| Pseudomonas lactucae CFBP13502 | 0.53 | GEMAOFIL_00034 | | Bifunctional (p)ppGpp synthase/hydrolase SpoT | 0.35 | GEMAOFIL_05151 | | Riboflavin biosynthesis protein | — | — |
| Marinobacter adhaerens HP15 | 0.50 | HP15_305 | | guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.38 | HP15_579 | | bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein | — | — |
| Dyella japonica UNC79MFTsu3.2 | 0.48 | ABZR86_RS11850 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.45 | ABZR86_RS03435 | | GTP cyclohydrolase II | — | — |
| Dechlorosoma suillum PS | 0.47 | Dsui_0500 | | (p)ppGpp synthetase, RelA/SpoT family | 0.36 | Dsui_0717 | | GTP cyclohydrolase II | — | — |
| Ralstonia solanacearum UW163 | 0.44 | UW163_RS10410 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.45 | UW163_RS21235 | | GTP cyclohydrolase II RibA | — | — |
| Ralstonia solanacearum IBSBF1503 | 0.44 | RALBFv3_RS03315 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.45 | RALBFv3_RS17905 | | GTP cyclohydrolase II RibA | low | > 76 |
| Cupriavidus basilensis FW507-4G11 | 0.44 | RR42_RS04920 | | guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.33 | RR42_RS29255 | | GTP cyclohydrolase | — | — |
| Castellaniella sp019104865 MT123 | 0.44 | ABCV34_RS03095 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.36 | ABCV34_RS00955 | | GTP cyclohydrolase II | — | — |
Not shown: 60 genomes with orthologs for CSW01_13675 only; 2 genomes with orthologs for CSW01_06380 only