Conservation of cofitness between CSW01_09955 and CSW01_01845 in Vibrio cholerae E7946 ATCC 55056

68 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_09955 L-asparaginase 1 1.0 CSW01_01845 protease modulator HflK 0.38 17
Enterobacter sp. TBS_079 0.74 MPMX20_01849 L-asparaginase 1 0.46 MPMX20_00455 Modulator of FtsH protease HflK 0.18 25
Klebsiella pneumoniae MKP103 0.73 KDGMDA_19250 asparaginase 0.48 KDGMDA_11045 FtsH protease activity modulator HflK low > 95
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.73 GFF3482 L-asparaginase I, cytoplasmic (EC 3.5.1.1) 0.48 GFF827 HflK protein low > 78
Pantoea sp. MT58 0.73 IAI47_08965 asparaginase 0.47 IAI47_02600 FtsH protease activity modulator HflK low > 76
Enterobacter asburiae PDN3 0.73 EX28DRAFT_1768 L-asparaginase, type I 0.48 EX28DRAFT_3371 HflK protein low > 76
Escherichia coli ECRC62 0.73 BNILDI_16105 ansA asparaginase 0.48 BNILDI_06980 hflK FtsH protease activity modulator HflK low > 75
Escherichia coli ECRC102 0.73 NIAGMN_01260 ansA asparaginase 0.48 NIAGMN_10095 hflK FtsH protease activity modulator HflK — —
Escherichia coli ECRC98 0.73 JDDGAC_01380 ansA asparaginase 0.48 JDDGAC_15885 hflK FtsH protease activity modulator HflK low > 87
Pantoea agglomerans CFBP13505 P0401 0.73 PagCFBP13505_RS02800 asparaginase 0.46 PagCFBP13505_RS11195 FtsH protease activity modulator HflK low > 74
Escherichia coli ECRC101 0.73 MCAODC_18605 ansA asparaginase 0.48 MCAODC_02760 hflK FtsH protease activity modulator HflK low > 87
Escherichia coli ECRC100 0.73 OKFHMN_26805 ansA asparaginase 0.48 OKFHMN_12245 hflK FtsH protease activity modulator HflK low > 79
Escherichia coli BL21 0.73 ECD_01736 cytoplasmic L-asparaginase 1 0.48 ECD_04041 modulator for HflB protease specific for phage lambda cII repressor low > 61
Serratia liquefaciens MT49 0.73 IAI46_14330 asparaginase 0.45 IAI46_01635 FtsH protease activity modulator HflK — —
Escherichia coli BW25113 0.73 b1767 ansA cytoplasmic asparaginase I (NCBI) 0.48 b4174 hflK modulator for HflB protease specific for phage lambda cII repressor (NCBI) low > 76
Escherichia coli ECRC99 0.73 KEDOAH_01305 ansA asparaginase 0.48 KEDOAH_15910 hflK FtsH protease activity modulator HflK — —
Escherichia coli ECOR38 0.73 HEPCGN_05180 ansA asparaginase 0.49 HEPCGN_10475 hflK FtsH protease activity modulator HflK low > 88
Escherichia coli ECOR27 0.73 NOLOHH_17320 ansA asparaginase 0.48 NOLOHH_04510 hflK FtsH protease activity modulator HflK low > 76
Klebsiella michiganensis M5al 0.73 BWI76_RS11580 L-asparaginase 1 0.45 BWI76_RS02545 protease modulator HflK low > 92
Escherichia coli HS(pFamp)R (ATCC 700891) 0.73 OHPLBJKB_01965 L-asparaginase 1 0.48 OHPLBJKB_03868 Modulator of FtsH protease HflK low > 74
Rahnella sp. WP5 0.73 EX31_RS06300 asparaginase 0.45 EX31_RS08810 FtsH protease activity modulator HflK low > 89
Escherichia coli Nissle 1917 0.73 ECOLIN_RS09860 asparaginase 0.49 ECOLIN_RS24240 FtsH protease activity modulator HflK — —
Escherichia fergusonii Becca 0.73 EFB2_02227 L-asparaginase 1 0.49 EFB2_04361 Modulator of FtsH protease HflK low > 86
Erwinia tracheiphila HP pepo 2.2 0.72 IJEDHG_22635 ansA asparaginase 0.46 IJEDHG_06855 hflK FtsH protease activity modulator HflK — —
Erwinia tracheiphila SCR3 0.72 LU632_RS12975 ansA asparaginase 0.46 LU632_RS02065 hflK FtsH protease activity modulator HflK low > 73
Erwinia amylovora T8 0.72 OLJFJH_13240 asparaginase 0.44 OLJFJH_02490 FtsH protease activity modulator HflK low > 58
Dickeya dadantii 3937 0.72 DDA3937_RS10285 asparaginase 0.48 DDA3937_RS18600 FtsH protease activity modulator HflK low > 74
Dickeya dianthicola 67-19 0.71 HGI48_RS10295 asparaginase 0.48 HGI48_RS18535 FtsH protease activity modulator HflK low > 71
Pectobacterium carotovorum WPP14 0.71 HER17_RS11110 asparaginase 0.46 HER17_RS02595 FtsH protease activity modulator HflK low > 75
Dickeya dianthicola ME23 0.71 DZA65_RS10770 asparaginase 0.48 DZA65_RS19670 FtsH protease activity modulator HflK low > 75
Alteromonas macleodii MIT1002 0.71 MIT1002_01844 L-asparaginase 1 0.48 MIT1002_03786 Modulator of FtsH protease HflK low > 70
Shewanella loihica PV-4 0.69 Shew_1940 ansA cytoplasmic asparaginase I (RefSeq) 0.50 Shew_0568 HflK protein (RefSeq) — —
Shewanella amazonensis SB2B 0.68 Sama_1722 ansA cytoplasmic asparaginase I (RefSeq) 0.47 Sama_3023 hflK protein (RefSeq) 0.42 48
Shewanella oneidensis MR-1 0.68 SO2421 ansA L-asparaginase I (NCBI ptt file) 0.50 SO0605 hflK hflK protein (NCBI ptt file) low > 76
Shewanella sp. ANA-3 0.68 Shewana3_1963 ansA cytoplasmic asparaginase I (RefSeq) 0.51 Shewana3_0599 HflK protein (RefSeq) low > 73
Kangiella aquimarina DSM 16071 0.55 B158DRAFT_1792 L-asparaginases, type I 0.31 B158DRAFT_1954 protease FtsH subunit HflK low > 40
Azospirillum sp. SherDot2 0.32 MPMX19_00090 L-asparaginase 1 0.23 MPMX19_01251 Modulator of FtsH protease HflK — —
Pseudomonas sp. S08-1 0.29 OH686_13275 L-asparaginase I, cytoplasmic 0.34 OH686_09460 HflK protein low > 80
Pseudomonas stutzeri RCH2 0.28 Psest_4078 L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D 0.34 Psest_0685 HflK protein — —
Pseudomonas fluorescens FW300-N1B4 0.27 Pf1N1B4_2023 L-asparaginase (EC 3.5.1.1) (from data) 0.37 Pf1N1B4_1410 HflK protein — —
Pseudomonas fluorescens FW300-N2E3 0.27 AO353_09960 L-asparaginase (EC 3.5.1.1) (from data) 0.36 AO353_13155 hypothetical protein low > 101
Pseudomonas simiae WCS417 0.27 PS417_28140 asparaginase 0.35 PS417_02500 membrane protein — —
Pseudomonas segetis P6 0.26 MPMX49_00165 L-asparaginase 1 0.36 MPMX49_04151 Modulator of FtsH protease HflK 0.74 33
Pseudomonas fluorescens GW456-L13 0.26 PfGW456L13_740 L-asparaginase (EC 3.5.1.1) (from data) 0.35 PfGW456L13_152 HflK protein 0.24 80
Pseudomonas sp. DMC3 0.26 GFF490 L-asparaginase 1 0.35 GFF3222 Modulator of FtsH protease HflK low > 89
Pseudomonas fluorescens FW300-N2E2 0.26 Pf6N2E2_4087 L-asparaginase (EC 3.5.1.1) (from data) 0.35 Pf6N2E2_3612 HflK protein low > 103
Pseudomonas fluorescens FW300-N2C3 0.26 AO356_11100 L-asparaginase (EC 3.5.1.1) (from data) 0.36 AO356_08645 hypothetical protein low > 104
Pseudomonas syringae pv. syringae B728a ΔmexB 0.26 Psyr_5053 asparaginase 0.35 Psyr_0574 protease FtsH subunit HflK low > 86
Pseudomonas syringae pv. syringae B728a 0.26 Psyr_5053 asparaginase 0.35 Psyr_0574 protease FtsH subunit HflK low > 86
Pseudomonas lactucae CFBP13502 0.26 GEMAOFIL_00094 L-asparaginase 1 0.35 GEMAOFIL_00738 Modulator of FtsH protease HflK low > 96
Pseudomonas sp. RS175 0.25 PFR28_04501 L-asparaginase 1 0.36 PFR28_05123 Modulator of FtsH protease HflK low > 88
Pseudomonas putida KT2440 0.25 PP_0495 type 1 L-asparaginase 0.34 PP_4892 integral membrane ATP-dependent zinc metallopeptidase / HflK-HflC complex low > 96
Pseudomonas aeruginosa PA14 0.25 IKLFDK_11055 asparaginase 0.36 IKLFDK_28830 FtsH protease activity modulator HflK — —
Pseudomonas aeruginosa PUPa3 0.25 DQ20_RS39875 asparaginase 0.36 DQ20_RS51555 hflK;go_component=outer FtsH protease activity modulator HflK low > 101
Pseudomonas aeruginosa MRSN321 0.25 DY961_RS17645 asparaginase 0.36 DY961_RS10500 hflK;go_component=outer FtsH protease activity modulator HflK 0.37 91
Pseudomonas sp. SVBP6 0.25 COO64_RS15980 asparaginase 0.34 COO64_RS17910 hflK FtsH protease activity modulator HflK low > 93
Pseudomonas fluorescens SBW25 0.24 PFLU_RS29825 asparaginase 0.36 PFLU_RS02580 FtsH protease activity modulator HflK low > 109
Pseudomonas fluorescens SBW25-INTG 0.24 PFLU_RS29825 asparaginase 0.36 PFLU_RS02580 FtsH protease activity modulator HflK 0.25 22
Pseudomonas sp. BP01 0.24 JOY50_RS20220 asparaginase 0.34 JOY50_RS17240 hflK FtsH protease activity modulator HflK low > 84
Ralstonia solanacearum UW163 0.11 UW163_RS13215 asparaginase 0.33 UW163_RS12775 FtsH protease activity modulator HflK — —
Ralstonia solanacearum IBSBF1503 0.11 RALBFv3_RS15770 asparaginase 0.33 RALBFv3_RS15310 FtsH protease activity modulator HflK — —
Ralstonia sp. UNC404CL21Col 0.11 ABZR87_RS11340 asparaginase 0.32 ABZR87_RS10950 FtsH protease activity modulator HflK low > 80
Ralstonia solanacearum PSI07 0.11 RPSI07_RS17595 asparaginase 0.34 RPSI07_RS18065 FtsH protease activity modulator HflK 0.45 32
Ralstonia solanacearum GMI1000 0.11 RS_RS06550 asparaginase 0.31 RS_RS06120 FtsH protease activity modulator HflK low > 80
Variovorax sp. SCN45 0.11 GFF356 L-asparaginase (EC 3.5.1.1) 0.33 GFF1002 HflK protein low > 127
Agrobacterium fabrum C58 0.10 Atu3791 L-asparaginase 0.22 Atu2045 HFLK protein low > 89
Cupriavidus basilensis FW507-4G11 0.10 RR42_RS12610 glutaminase 0.32 RR42_RS13105 membrane protein — —
Acidovorax sp. GW101-3H11 0.09 Ac3H11_2391 L-asparaginase (EC 3.5.1.1) 0.31 Ac3H11_1801 HflK protein low > 79
Hydrogenophaga sp. GW460-11-11-14-LB1 0.08 GFF4502 L-asparaginase (EC 3.5.1.1) 0.33 GFF4856 HflK protein low > 90

Not shown: 21 genomes with orthologs for CSW01_09955 only; 20 genomes with orthologs for CSW01_01845 only