Conservation of cofitness between CSW01_11730 and CSW01_01485 in Vibrio cholerae E7946 ATCC 55056

66 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_11730 2-dehydropantoate 2-reductase 1.0 CSW01_01485 transcriptional regulator 0.82 13
Rahnella sp. WP5 0.38 EX31_RS22180 2-dehydropantoate 2-reductase 0.54 EX31_RS05060 gluconate operon transcriptional repressor GntR low > 89
Enterobacter sp. TBS_079 0.36 MPMX20_01016 2-dehydropantoate 2-reductase 0.52 MPMX20_04319 HTH-type transcriptional regulator GntR low > 85
Serratia liquefaciens MT49 0.35 IAI46_04950 2-dehydropantoate 2-reductase 0.54 IAI46_23965 gluconate operon transcriptional repressor GntR low > 87
Escherichia coli ECRC99 0.35 KEDOAH_19570 panE 2-dehydropantoate 2-reductase 0.52 KEDOAH_11305 gntR gluconate operon transcriptional repressor GntR — —
Escherichia coli ECRC100 0.35 OKFHMN_08395 panE 2-dehydropantoate 2-reductase 0.52 OKFHMN_16835 gntR gluconate operon transcriptional repressor GntR low > 79
Escherichia coli BW25113 0.35 b0425 panE 2-dehydropantoate 2-reductase (NCBI) 0.52 b3438 gntR DNA-binding transcriptional repressor (NCBI) low > 76
Escherichia coli ECRC101 0.35 MCAODC_27620 panE 2-dehydropantoate 2-reductase 0.52 MCAODC_07365 gntR gluconate operon transcriptional repressor GntR low > 87
Escherichia coli ECRC102 0.35 NIAGMN_06450 panE 2-dehydropantoate 2-reductase 0.52 NIAGMN_14605 gntR gluconate operon transcriptional repressor GntR low > 80
Escherichia coli ECRC98 0.35 JDDGAC_12050 panE 2-dehydropantoate 2-reductase 0.52 JDDGAC_20465 gntR gluconate operon transcriptional repressor GntR low > 87
Escherichia coli ECRC62 0.35 BNILDI_22760 panE 2-dehydropantoate 2-reductase 0.52 BNILDI_02870 gntR gluconate operon transcriptional repressor GntR low > 75
Escherichia coli ECOR27 0.35 NOLOHH_01345 panE 2-dehydropantoate 2-reductase 0.51 NOLOHH_08635 gntR gluconate operon transcriptional repressor GntR low > 76
Escherichia coli BL21 0.35 ECD_00373 2-dehydropantoate reductase, NADPH-specific 0.51 ECD_03289 d-gluconate inducible gluconate regulon transcriptional repressor low > 61
Enterobacter asburiae PDN3 0.35 EX28DRAFT_2546 2-dehydropantoate 2-reductase 0.51 EX28DRAFT_4274 transcriptional regulator, LacI family low > 76
Escherichia coli HS(pFamp)R (ATCC 700891) 0.35 OHPLBJKB_03251 2-dehydropantoate 2-reductase 0.52 OHPLBJKB_00264 HTH-type transcriptional regulator GntR low > 74
Escherichia coli ECOR38 0.35 HEPCGN_07025 panE 2-dehydropantoate 2-reductase 0.52 HEPCGN_15660 gntR gluconate operon transcriptional repressor GntR low > 88
Escherichia fergusonii Becca 0.35 EFB2_03632 2-dehydropantoate 2-reductase 0.52 EFB2_00382 HTH-type transcriptional regulator GntR low > 86
Klebsiella pneumoniae MKP103 0.35 KDGMDA_14500 2-dehydropantoate 2-reductase 0.51 KDGMDA_07120 gluconate operon transcriptional repressor GntR low > 95
Pectobacterium carotovorum WPP14 0.34 HER17_RS15910 2-dehydropantoate 2-reductase 0.52 HER17_RS01450 gluconate operon transcriptional repressor GntR low > 75
Escherichia coli Nissle 1917 0.34 ECOLIN_RS02560 2-dehydropantoate 2-reductase 0.52 ECOLIN_RS19675 gluconate operon transcriptional repressor GntR low > 55
Klebsiella michiganensis M5al 0.34 BWI76_RS06405 2-dehydropantoate 2-reductase 0.51 BWI76_RS26245 transcriptional regulator low > 92
Dickeya dianthicola ME23 0.34 DZA65_RS05940 2-dehydropantoate 2-reductase 0.55 DZA65_RS20970 gluconate operon transcriptional repressor GntR low > 75
Dickeya dianthicola 67-19 0.33 HGI48_RS05615 2-dehydropantoate 2-reductase 0.55 HGI48_RS19900 gluconate operon transcriptional repressor GntR low > 71
Pantoea agglomerans CFBP13505 P0401 0.32 PagCFBP13505_RS10480 2-dehydropantoate 2-reductase 0.50 PagCFBP13505_RS18155 gluconate operon transcriptional repressor GntR low > 74
Dickeya dadantii 3937 0.32 DDA3937_RS05555 2-dehydropantoate 2-reductase 0.55 DDA3937_RS19785 gluconate operon transcriptional repressor GntR low > 74
Pantoea sp. MT58 0.32 IAI47_14715 2-dehydropantoate 2-reductase 0.52 IAI47_01650 gluconate operon transcriptional repressor GntR low > 76
Erwinia tracheiphila HP pepo 2.2 0.32 IJEDHG_16335 panE 2-dehydropantoate 2-reductase 0.54 IJEDHG_08040 gntR gluconate operon transcriptional repressor GntR low > 61
Erwinia tracheiphila SCR3 0.32 LU632_RS18455 panE 2-dehydropantoate 2-reductase 0.53 LU632_RS19160 gntR gluconate operon transcriptional repressor GntR low > 73
Erwinia amylovora T8 0.32 OLJFJH_18040 2-dehydropantoate 2-reductase 0.56 OLJFJH_04280 gluconate operon transcriptional repressor GntR low > 58
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.30 GFF4336 2-dehydropantoate 2-reductase (EC 1.1.1.169) 0.49 GFF570 Gluconate utilization system Gnt-I transcriptional repressor low > 78
Alteromonas macleodii MIT1002 0.28 MIT1002_01217 2-dehydropantoate 2-reductase 0.31 MIT1002_03475 Gluconate utilization system GNT-I transcriptional repressor low > 70
Pseudomonas sp. SVBP6 0.27 COO64_RS11970 putative 2-dehydropantoate 2-reductase 0.34 COO64_RS25590 LacI family DNA-binding transcriptional regulator low > 93
Pseudomonas stutzeri RCH2 0.27 Psest_1140 2-dehydropantoate 2-reductase 0.34 Psest_2126 Transcriptional regulators low > 67
Pseudomonas syringae pv. syringae B728a ΔmexB 0.25 Psyr_4088 ketopantoate reductase 0.32 Psyr_3336 transcriptional regulator, LacI family low > 86
Pseudomonas syringae pv. syringae B728a 0.25 Psyr_4088 ketopantoate reductase 0.32 Psyr_3336 transcriptional regulator, LacI family low > 86
Pseudomonas aeruginosa PUPa3 0.25 DQ20_RS56950 putative 2-dehydropantoate 2-reductase 0.36 DQ20_RS59230 gntR;inference=COORDINATES LacI family DNA-binding transcriptional regulator GntR low > 101
Pseudomonas aeruginosa MRSN321 0.24 DY961_RS24500 putative 2-dehydropantoate 2-reductase 0.36 DY961_RS17990 gntR;inference=COORDINATES LacI family DNA-binding transcriptional regulator GntR low > 100
Pseudomonas aeruginosa PA14 0.24 IKLFDK_02110 putative 2-dehydropantoate 2-reductase 0.36 IKLFDK_11375 LacI family DNA-binding transcriptional regulator GntR low > 98
Pseudomonas fluorescens FW300-N2C3 0.24 AO356_17955 2-dehydropantoate 2-reductase 0.34 AO356_05065 LacI family transcriptional regulator low > 104
Pseudomonas sp. RS175 0.24 PFR28_03426 2-dehydropantoate 2-reductase 0.34 PFR28_00593 HTH-type transcriptional regulator GntR low > 88
Pseudomonas fluorescens FW300-N2E2 0.24 Pf6N2E2_5521 2-dehydropantoate 2-reductase (EC 1.1.1.169) 0.34 Pf6N2E2_2865 Gluconate utilization system Gnt-I transcriptional repressor low > 103
Pseudomonas putida KT2440 0.24 PP_1351 putative 2-dehydropantoate 2-reductase 0.31 PP_3415 Transcriptional regulator, LacI family low > 96
Pseudomonas segetis P6 0.23 MPMX49_03786 2-dehydropantoate 2-reductase 0.33 MPMX49_02373 HTH-type transcriptional regulator GntR low > 75
Pseudomonas sp. BP01 0.23 JOY50_RS15040 putative 2-dehydropantoate 2-reductase 0.31 JOY50_RS23605 LacI family DNA-binding transcriptional regulator low > 84
Pseudomonas fluorescens FW300-N2E3 0.23 AO353_03645 2-dehydropantoate 2-reductase 0.33 AO353_03255 LacI family transcriptional regulator low > 101
Pseudomonas orientalis W4I3 0.22 QF045_RS24680 putative 2-dehydropantoate 2-reductase 0.34 QF045_RS24095 LacI family DNA-binding transcriptional regulator low > 93
Pseudomonas fluorescens GW456-L13 0.22 PfGW456L13_1839 2-dehydropantoate 2-reductase (EC 1.1.1.169) 0.34 PfGW456L13_1925 Gluconate utilization system Gnt-I transcriptional repressor low > 87
Pseudomonas fluorescens FW300-N1B4 0.22 Pf1N1B4_651 2-dehydropantoate 2-reductase (EC 1.1.1.169) 0.35 Pf1N1B4_558 Gluconate utilization system Gnt-I transcriptional repressor low > 87
Pseudomonas simiae WCS417 0.22 PS417_22515 2-dehydropantoate 2-reductase 0.33 PS417_21990 LacI family transcriptional regulator low > 88
Pseudomonas sp. DMC3 0.22 GFF5199 2-dehydropantoate 2-reductase 0.33 GFF5268 HTH-type transcriptional regulator GntR low > 89
Pseudomonas fluorescens SBW25 0.21 PFLU_RS24155 putative 2-dehydropantoate 2-reductase 0.34 PFLU_RS23595 LacI family DNA-binding transcriptional regulator low > 109
Pseudomonas fluorescens SBW25-INTG 0.21 PFLU_RS24155 putative 2-dehydropantoate 2-reductase 0.34 PFLU_RS23595 LacI family DNA-binding transcriptional regulator low > 109
Pseudomonas lactucae CFBP13502 0.21 GEMAOFIL_04655 2-dehydropantoate 2-reductase 0.34 GEMAOFIL_04536 HTH-type transcriptional regulator GntR low > 96
Herbaspirillum seropedicae SmR1 0.20 HSERO_RS09230 2-dehydropantoate 2-reductase 0.34 HSERO_RS05460 LacI family transcription regulator low > 78
Paraburkholderia sabiae LMG 24235 0.19 QEN71_RS38425 ketopantoate reductase family protein 0.29 QEN71_RS13585 LacI family DNA-binding transcriptional regulator low > 153
Variovorax sp. SCN45 0.19 GFF3590 2-dehydropantoate 2-reductase (EC 1.1.1.169) 0.30 GFF7257 KEGG: LacI family transcriptional regulator, gluconate utilization system Gnt-I transcriptional repressor low > 127
Variovorax sp. OAS795 0.18 ABID97_RS00870 2-dehydropantoate 2-reductase 0.29 ABID97_RS01205 LacI family DNA-binding transcriptional regulator low > 91
Acidovorax sp. GW101-3H11 0.18 Ac3H11_2346 2-dehydropantoate 2-reductase (EC 1.1.1.169) 0.29 Ac3H11_3230 Gluconate utilization system Gnt-I transcriptional repressor low > 79
Ralstonia sp. UNC404CL21Col 0.16 ABZR87_RS15450 2-dehydropantoate 2-reductase 0.26 ABZR87_RS18255 LacI family DNA-binding transcriptional regulator low > 80
Paraburkholderia bryophila 376MFSha3.1 0.15 H281DRAFT_01683 ketopantoate reductase (EC 1.1.1.169) 0.30 H281DRAFT_05920 transcriptional regulator, LacI family low > 103
Cupriavidus basilensis FW507-4G11 0.14 RR42_RS32960 2-dehydropantoate 2-reductase 0.26 RR42_RS22645 GntR family transcriptional regulator low > 128
Burkholderia phytofirmans PsJN 0.14 BPHYT_RS27355 2-dehydropantoate 2-reductase 0.32 BPHYT_RS00410 LacI family transcription regulator low > 109
Azospirillum brasilense Sp245 0.09 AZOBR_RS12955 2-dehydropantoate 2-reductase 0.31 AZOBR_RS15720 LacI family transcription regulator — —
Ralstonia solanacearum GMI1000 0.09 RS_RS00860 2-dehydropantoate 2-reductase 0.26 RS_RS24865 LacI family DNA-binding transcriptional regulator low > 80
Hydrogenophaga sp. GW460-11-11-14-LB1 0.09 GFF1821 2-dehydropantoate 2-reductase (EC 1.1.1.169) 0.30 GFF5509 Gluconate utilization system Gnt-I transcriptional repressor low > 90
Ralstonia solanacearum UW163 0.08 UW163_RS03340 2-dehydropantoate 2-reductase 0.24 UW163_RS16860 GntR family transcriptional regulator — —
Ralstonia solanacearum IBSBF1503 0.08 RALBFv3_RS10240 2-dehydropantoate 2-reductase 0.24 RALBFv3_RS16125 GntR family transcriptional regulator low > 76

Not shown: 19 genomes with orthologs for CSW01_11730 only; 9 genomes with orthologs for CSW01_01485 only