Conservation of cofitness between BWI76_RS06780 and BWI76_RS25215 in Klebsiella michiganensis M5al

54 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS06780 MexE family multidrug efflux RND transporter periplasmic adaptor subunit 1.0 BWI76_RS25215 phospholipid-binding protein MlaC 0.49 7
Enterobacter sp. TBS_079 0.87 MPMX20_01065 Multidrug efflux pump subunit AcrA 0.93 MPMX20_04098 Intermembrane phospholipid transport system binding protein MlaC low > 85
Enterobacter asburiae PDN3 0.84 EX28DRAFT_2495 RND family efflux transporter, MFP subunit 0.93 EX28DRAFT_3246 ABC-type transport system involved in resistance to organic solvents, auxiliary component low > 76
Escherichia coli ECRC62 0.83 BNILDI_22550 acrA multidrug efflux RND transporter periplasmic adaptor subunit AcrA 0.91 BNILDI_01745 mlaC phospholipid-binding protein MlaC low > 75
Escherichia coli BL21 0.83 ECD_00414 multidrug efflux system 0.91 ECD_03057 ABC transporter maintaining OM lipid asymmetry, periplasmic binding protein low > 61
Escherichia coli ECRC98 0.83 JDDGAC_11850 acrA multidrug efflux RND transporter periplasmic adaptor subunit AcrA 0.91 JDDGAC_21615 mlaC phospholipid-binding protein MlaC low > 86
Escherichia coli ECOR27 0.83 NOLOHH_01135 acrA multidrug efflux RND transporter periplasmic adaptor subunit AcrA 0.91 NOLOHH_09790 mlaC phospholipid-binding protein MlaC low > 75
Escherichia coli BW25113 0.83 b0463 acrA multidrug efflux system (NCBI) 0.91 b3192 yrbC predicted ABC-type organic solvent transporter (NCBI) 0.33 26
Escherichia coli ECRC99 0.83 KEDOAH_19765 acrA multidrug efflux RND transporter periplasmic adaptor subunit AcrA 0.91 KEDOAH_10160 mlaC phospholipid-binding protein MlaC
Escherichia coli ECRC102 0.83 NIAGMN_06255 acrA multidrug efflux RND transporter periplasmic adaptor subunit AcrA 0.91 NIAGMN_15750 mlaC phospholipid-binding protein MlaC
Escherichia coli HS(pFamp)R (ATCC 700891) 0.83 OHPLBJKB_03211 Multidrug efflux pump subunit AcrA 0.91 OHPLBJKB_00508 putative phospholipid-binding protein MlaC 0.47 18
Escherichia coli ECRC101 0.83 MCAODC_27425 acrA multidrug efflux RND transporter periplasmic adaptor subunit AcrA 0.91 MCAODC_08510 mlaC phospholipid-binding protein MlaC low > 87
Escherichia coli ECRC100 0.83 OKFHMN_08200 acrA multidrug efflux RND transporter periplasmic adaptor subunit AcrA 0.91 OKFHMN_17990 mlaC phospholipid-binding protein MlaC low > 80
Escherichia fergusonii Becca 0.82 EFB2_03595 Multidrug efflux pump subunit AcrA 0.91 EFB2_00631 Intermembrane phospholipid transport system binding protein MlaC low > 86
Escherichia coli Nissle 1917 0.82 ECOLIN_RS02755 multidrug efflux RND transporter periplasmic adaptor subunit AcrA 0.92 ECOLIN_RS18375 phospholipid-binding protein MlaC
Escherichia coli ECOR38 0.82 HEPCGN_06815 acrA multidrug efflux RND transporter periplasmic adaptor subunit AcrA 0.91 HEPCGN_16865 mlaC phospholipid-binding protein MlaC low > 87
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.78 GFF4380 Membrane fusion protein of RND family multidrug efflux pump 0.94 GFF2936 Uncharacterized ABC transporter, auxiliary component YrbC low > 78
Pantoea sp. MT58 0.74 IAI47_14510 efflux RND transporter periplasmic adaptor subunit 0.84 IAI47_17130 phospholipid-binding protein MlaC 0.47 23
Rahnella sp. WP5 0.74 EX31_RS22475 efflux RND transporter periplasmic adaptor subunit 0.75 EX31_RS12450 phospholipid-binding protein MlaC low > 89
Serratia liquefaciens MT49 0.74 IAI46_05190 multidrug efflux RND transporter periplasmic adaptor subunit SdeX 0.81 IAI46_22415 phospholipid-binding protein MlaC low > 86
Erwinia tracheiphila SCR3 0.74 LU632_RS18180 efflux RND transporter periplasmic adaptor subunit 0.78 LU632_RS21230 mlaC phospholipid-binding protein MlaC
Dickeya dadantii 3937 0.71 DDA3937_RS05740 efflux RND transporter periplasmic adaptor subunit 0.74 DDA3937_RS01580 phospholipid-binding protein MlaC low > 74
Dickeya dianthicola 67-19 0.69 HGI48_RS05795 efflux RND transporter periplasmic adaptor subunit 0.74 HGI48_RS01495 phospholipid-binding protein MlaC low > 71
Dickeya dianthicola ME23 0.69 DZA65_RS06120 efflux RND transporter periplasmic adaptor subunit 0.74 DZA65_RS01560 phospholipid-binding protein MlaC 0.59 60
Pectobacterium carotovorum WPP14 0.68 HER17_RS15735 efflux RND transporter periplasmic adaptor subunit 0.78 HER17_RS20010 phospholipid-binding protein MlaC low > 75
Pseudomonas putida KT2440 0.48 PP_1386 Probable efflux pump periplasmic linker TtgA 0.12 PP_0961 toluene tolerance protein 0.57 4
Xanthomonas campestris pv. campestris strain 8004 0.47 Xcc-8004.1793.1 RND efflux system, membrane fusion protein CmeA 0.18 Xcc-8004.5367.1 Uncharacterized ABC transporter, auxiliary component YrbC low > 74
Herbaspirillum seropedicae SmR1 0.47 HSERO_RS06810 hemolysin D 0.18 HSERO_RS20380 hypothetical protein
Pseudomonas fluorescens FW300-N2E3 0.47 AO353_17300 antibiotic transporter 0.12 AO353_05135 toluene tolerance protein 0.46 25
Azospirillum brasilense Sp245 0.46 AZOBR_RS30180 hemolysin D 0.17 AZOBR_RS09525 toluene tolerance protein low > 97
Burkholderia phytofirmans PsJN 0.46 BPHYT_RS34600 hemolysin D 0.17 BPHYT_RS17745 toluene tolerance family protein low > 109
Paraburkholderia sabiae LMG 24235 0.46 QEN71_RS29870 efflux RND transporter periplasmic adaptor subunit 0.19 QEN71_RS27900 ABC transporter substrate-binding protein 0.51 74
Azospirillum sp. SherDot2 0.46 MPMX19_05883 Multidrug resistance protein MexA 0.18 MPMX19_00632 Intermembrane phospholipid transport system binding protein MlaC low > 112
Dyella japonica UNC79MFTsu3.2 0.45 ABZR86_RS18280 efflux RND transporter periplasmic adaptor subunit 0.21 ABZR86_RS11870 phospholipid-binding protein MlaC low > 74
Cupriavidus basilensis FW507-4G11 0.45 RR42_RS32415 hemolysin D 0.17 RR42_RS18950 hypothetical protein low > 128
Paraburkholderia bryophila 376MFSha3.1 0.45 H281DRAFT_01000 membrane fusion protein, multidrug efflux system 0.17 H281DRAFT_05645 phospholipid transport system substrate-binding protein low > 103
Shewanella amazonensis SB2B 0.44 Sama_3553 multidrug resistance protein AcrA/AcrE family (RefSeq) 0.35 Sama_3078 hypothetical protein (RefSeq) low > 62
Ralstonia solanacearum IBSBF1503 0.44 RALBFv3_RS19790 efflux RND transporter periplasmic adaptor subunit 0.16 RALBFv3_RS06880 hypothetical protein low > 76
Ralstonia solanacearum UW163 0.44 UW163_RS19385 efflux RND transporter periplasmic adaptor subunit 0.16 UW163_RS06735 hypothetical protein
Ralstonia sp. UNC404CL21Col 0.44 ABZR87_RS05310 efflux RND transporter periplasmic adaptor subunit 0.17 ABZR87_RS02535 phospholipid-binding protein MlaC low > 80
Ralstonia solanacearum GMI1000 0.44 RS_RS21035 efflux RND transporter periplasmic adaptor subunit 0.16 RS_RS14825 hypothetical protein low > 80
Shewanella oneidensis MR-1 0.44 SO4693 multidrug resistance protein, AcrA/AcrE family (NCBI ptt file) 0.34 SO3951 conserved hypothetical protein (NCBI ptt file) low > 76
Shewanella sp. ANA-3 0.44 Shewana3_4046 RND family efflux transporter MFP subunit (RefSeq) 0.34 Shewana3_0681 toluene tolerance family protein (RefSeq) low > 73
Ralstonia solanacearum PSI07 0.44 RPSI07_RS23900 efflux RND transporter periplasmic adaptor subunit 0.17 RPSI07_RS10355 hypothetical protein low > 81
Acinetobacter radioresistens SK82 0.40 MPMX26_00690 Multidrug efflux pump subunit AcrA 0.16 MPMX26_02738 Intermembrane phospholipid transport system binding protein MlaC low > 36
Variovorax sp. OAS795 0.38 ABID97_RS00320 efflux RND transporter periplasmic adaptor subunit 0.16 ABID97_RS23195 ABC transporter substrate-binding protein 0.52 23
Hydrogenophaga sp. GW460-11-11-14-LB1 0.38 GFF5686 RND efflux system, membrane fusion protein CmeA 0.18 GFF1321 Uncharacterized ABC transporter, auxiliary component YrbC low > 90
Acidovorax sp. GW101-3H11 0.34 Ac3H11_4449 RND efflux system, membrane fusion protein CmeA 0.15 Ac3H11_4716 Toluene tolerance precursor low > 79
Rhodanobacter sp. FW510-T8 0.34 OKGIIK_09165 acrA efflux transporter periplasmic adaptor subunit 0.21 OKGIIK_12120 Toluene tolerance protein low > 52
Kangiella aquimarina DSM 16071 0.33 B158DRAFT_0734 RND family efflux transporter, MFP subunit 0.19 B158DRAFT_1389 ABC-type transport system involved in resistance to organic solvents, auxiliary component low > 40
Castellaniella sp019104865 MT123 0.33 ABCV34_RS04230 efflux RND transporter periplasmic adaptor subunit 0.17 ABCV34_RS11200 ABC transporter substrate-binding protein
Rhodanobacter denitrificans FW104-10B01 0.31 LRK54_RS02095 efflux RND transporter periplasmic adaptor subunit 0.20 LRK54_RS11775 ABC transporter substrate-binding protein low > 59
Rhodanobacter denitrificans MT42 0.31 LRK55_RS01870 efflux RND transporter periplasmic adaptor subunit 0.20 LRK55_RS11500 ABC transporter substrate-binding protein low > 63
Lysobacter sp. OAE881 0.30 ABIE51_RS17985 efflux RND transporter periplasmic adaptor subunit 0.16 ABIE51_RS01000 ABC transporter substrate-binding protein low > 62
Desulfovibrio vulgaris Miyazaki F 0.28 DvMF_2164 efflux transporter, RND family, MFP subunit (RefSeq) 0.13 DvMF_0855 toluene tolerance family protein (RefSeq) low > 51

Not shown: 19 genomes with orthologs for BWI76_RS06780 only; 6 genomes with orthologs for BWI76_RS25215 only