Conservation of cofitness between BWI76_RS12790 and BWI76_RS08765 in Klebsiella michiganensis M5al

53 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS12790 lactate dehydrogenase 1.0 BWI76_RS08765 8-amino-7-oxononanoate synthase 0.22 3
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.93 GFF2638 D-lactate dehydrogenase (EC 1.1.1.28) 0.69 GFF672 8-amino-7-oxononanoate synthase (EC 2.3.1.47) low > 78
Enterobacter asburiae PDN3 0.92 EX28DRAFT_1435 Lactate dehydrogenase and related dehydrogenases 0.71 EX28DRAFT_2215 8-amino-7-oxononanoate synthase low > 76
Enterobacter sp. TBS_079 0.92 MPMX20_02132 D-lactate dehydrogenase 0.70 MPMX20_01404 8-amino-7-oxononanoate synthase low > 85
Escherichia coli BW25113 0.91 b1380 ldhA D-lactate dehydrogenase (NCBI) 0.67 b0776 bioF 8-amino-7-oxononanoate synthase (NCBI) low > 76
Escherichia coli ECOR38 0.91 HEPCGN_26050 ldhA D-lactate dehydrogenase 0.66 HEPCGN_01645 bioF 8-amino-7-oxononanoate synthase low > 87
Escherichia coli ECOR27 0.91 NOLOHH_19530 ldhA D-lactate dehydrogenase 0.66 NOLOHH_22765 bioF 8-amino-7-oxononanoate synthase low > 75
Escherichia coli BL21 0.91 ECD_01352 fermentative D-lactate dehydrogenase, NAD-dependent 0.67 ECD_00743 8-amino-7-oxononanoate synthase 0.53 7
Escherichia fergusonii Becca 0.91 EFB2_02576 D-lactate dehydrogenase 0.68 EFB2_03329 8-amino-7-oxononanoate synthase low > 86
Escherichia coli ECRC62 0.91 BNILDI_17985 ldhA D-lactate dehydrogenase 0.67 BNILDI_21035 bioF 8-amino-7-oxononanoate synthase low > 75
Escherichia coli HS(pFamp)R (ATCC 700891) 0.91 OHPLBJKB_02331 D-lactate dehydrogenase 0.67 OHPLBJKB_02937 8-amino-7-oxononanoate synthase low > 73
Escherichia coli ECRC101 0.91 MCAODC_16140 ldhA D-lactate dehydrogenase 0.67 MCAODC_25610 bioF 8-amino-7-oxononanoate synthase low > 87
Escherichia coli ECRC100 0.91 OKFHMN_01795 ldhA D-lactate dehydrogenase 0.67 OKFHMN_06395 bioF 8-amino-7-oxononanoate synthase low > 80
Escherichia coli ECRC102 0.91 NIAGMN_25930 ldhA D-lactate dehydrogenase 0.67 NIAGMN_04440 bioF 8-amino-7-oxononanoate synthase — —
Escherichia coli Nissle 1917 0.91 ECOLIN_RS08110 D-lactate dehydrogenase 0.68 ECOLIN_RS04135 8-amino-7-oxononanoate synthase — —
Escherichia coli ECRC98 0.91 JDDGAC_04285 ldhA D-lactate dehydrogenase 0.67 JDDGAC_10030 bioF 8-amino-7-oxononanoate synthase low > 86
Escherichia coli ECRC99 0.91 KEDOAH_26640 ldhA D-lactate dehydrogenase 0.67 KEDOAH_21515 bioF 8-amino-7-oxononanoate synthase — —
Serratia liquefaciens MT49 0.82 IAI46_13355 2-hydroxyacid dehydrogenase 0.58 IAI46_06530 8-amino-7-oxononanoate synthase low > 86
Pantoea sp. MT58 0.82 IAI47_09495 2-hydroxyacid dehydrogenase 0.56 IAI47_13525 8-amino-7-oxononanoate synthase low > 76
Dickeya dadantii 3937 0.79 DDA3937_RS12295 2-hydroxyacid dehydrogenase 0.64 DDA3937_RS08515 8-amino-7-oxononanoate synthase low > 74
Rahnella sp. WP5 0.79 EX31_RS06470 2-hydroxyacid dehydrogenase 0.58 EX31_RS23700 8-amino-7-oxononanoate synthase low > 89
Pectobacterium carotovorum WPP14 0.78 HER17_RS09630 2-hydroxyacid dehydrogenase 0.64 HER17_RS13455 8-amino-7-oxononanoate synthase low > 75
Shewanella loihica PV-4 0.67 Shew_0787 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding (RefSeq) 0.35 Shew_1720 8-amino-7-oxononanoate synthase (RefSeq) — —
Vibrio cholerae E7946 ATCC 55056 0.65 CSW01_14945 2-hydroxyacid dehydrogenase 0.48 CSW01_05650 8-amino-7-oxononanoate synthase low > 62
Shewanella oneidensis MR-1 0.64 SO0968 ldhA D-lactate dehydrogenase (NCBI ptt file) 0.34 SO2739 bioF 8-amino-7-oxononanoate synthase (NCBI ptt file) low > 76
Shewanella sp. ANA-3 0.64 Shewana3_3319 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding (RefSeq) 0.34 Shewana3_2518 aminotransferase, class I and II (RefSeq) — —
Shewanella amazonensis SB2B 0.63 Sama_0612 D-lactate dehydrogenase (RefSeq) 0.30 Sama_1439 8-amino-7-oxononanoate synthase (RefSeq) — —
Pseudomonas putida KT2440 0.53 PP_1649 D-lactate dehydrogenase 0.38 PP_0363 8-amino-7-oxononanoate synthase low > 96
Agrobacterium fabrum C58 0.51 Atu3870 D-lactate dehydrogenase 0.24 Atu3998 8-amino-7-oxononanoate synthase low > 89
Ralstonia solanacearum IBSBF1503 0.51 RALBFv3_RS07830 2-hydroxyacid dehydrogenase 0.30 RALBFv3_RS00820 8-amino-7-oxononanoate synthase low > 76
Ralstonia solanacearum UW163 0.51 UW163_RS05795 2-hydroxyacid dehydrogenase 0.30 UW163_RS14155 8-amino-7-oxononanoate synthase — —
Alteromonas macleodii MIT1002 0.51 MIT1002_01974 D-lactate dehydrogenase 0.38 MIT1002_01380 8-amino-7-oxononanoate synthase low > 70
Paraburkholderia graminis OAS925 0.51 ABIE53_006385 D-lactate dehydrogenase 0.35 ABIE53_000579 8-amino-7-oxononanoate synthase low > 113
Pseudomonas fluorescens FW300-N2C3 0.51 AO356_19040 hydroxyacid dehydrogenase 0.39 AO356_14140 8-amino-7-oxononanoate synthase low > 104
Pseudomonas sp. RS175 0.50 PFR28_03228 D-lactate dehydrogenase 0.40 PFR28_04102 8-amino-7-oxononanoate synthase low > 88
Pseudomonas sp. S08-1 0.50 OH686_18940 D-lactate dehydrogenase 0.39 OH686_10350 8-amino-7-oxononanoate synthase 0.76 4
Ralstonia solanacearum GMI1000 0.50 RS_RS15730 2-hydroxyacid dehydrogenase 0.32 RS_RS07435 8-amino-7-oxononanoate synthase low > 80
Pseudomonas fluorescens FW300-N2E3 0.50 AO353_02740 hydroxyacid dehydrogenase 0.40 AO353_07520 8-amino-7-oxononanoate synthase low > 101
Sphingomonas koreensis DSMZ 15582 0.50 Ga0059261_0219 Lactate dehydrogenase and related dehydrogenases 0.25 Ga0059261_3672 7-keto-8-aminopelargonate synthetase and related enzymes low > 68
Paraburkholderia bryophila 376MFSha3.1 0.50 H281DRAFT_04746 D-lactate dehydrogenase 0.34 H281DRAFT_02095 8-amino-7-oxononanoate synthase low > 103
Ralstonia sp. UNC404CL21Col 0.50 ABZR87_RS03505 2-hydroxyacid dehydrogenase 0.30 ABZR87_RS12340 8-amino-7-oxononanoate synthase low > 80
Pseudomonas fluorescens FW300-N2E2 0.50 Pf6N2E2_5719 D-lactate dehydrogenase (EC 1.1.1.28) 0.40 Pf6N2E2_4761 8-amino-7-oxononanoate synthase (EC 2.3.1.47) low > 103
Pseudomonas stutzeri RCH2 0.50 Psest_4064 Lactate dehydrogenase and related dehydrogenases 0.41 Psest_0412 8-amino-7-oxononanoate synthase low > 67
Pseudomonas fluorescens FW300-N1B4 0.50 Pf1N1B4_3500 D-lactate dehydrogenase (EC 1.1.1.28) 0.41 Pf1N1B4_2488 8-amino-7-oxononanoate synthase (EC 2.3.1.47) low > 87
Pseudomonas fluorescens GW456-L13 0.50 PfGW456L13_2028 D-lactate dehydrogenase (EC 1.1.1.28) 0.41 PfGW456L13_1148 8-amino-7-oxononanoate synthase (EC 2.3.1.47) low > 87
Ralstonia solanacearum PSI07 0.50 RPSI07_RS09445 2-hydroxyacid dehydrogenase 0.29 RPSI07_RS16700 8-amino-7-oxononanoate synthase low > 81
Burkholderia phytofirmans PsJN 0.49 BPHYT_RS03835 D-lactate dehydrogenase 0.34 BPHYT_RS02160 8-amino-7-oxononanoate synthase low > 109
Pseudomonas simiae WCS417 0.49 PS417_16375 2-hydroxyacid dehydrogenase 0.41 PS417_26000 8-amino-7-oxononanoate synthase low > 88
Paraburkholderia sabiae LMG 24235 0.49 QEN71_RS26130 2-hydroxyacid dehydrogenase 0.35 QEN71_RS01095 8-amino-7-oxononanoate synthase — —
Pseudomonas fluorescens SBW25-INTG 0.48 PFLU_RS18415 2-hydroxyacid dehydrogenase 0.41 PFLU_RS27645 8-amino-7-oxononanoate synthase low > 109
Pseudomonas fluorescens SBW25 0.48 PFLU_RS18415 2-hydroxyacid dehydrogenase 0.41 PFLU_RS27645 8-amino-7-oxononanoate synthase low > 109
Herbaspirillum seropedicae SmR1 0.46 HSERO_RS12550 D-lactate dehydrogenase 0.36 HSERO_RS12245 8-amino-7-oxononanoate synthase low > 78
Parabacteroides merdae CL09T00C40 0.46 HMPREF1078_RS01675 2-hydroxyacid dehydrogenase 0.30 HMPREF1078_RS15290 8-amino-7-oxononanoate synthase low > 61
Fusobacterium nucleatum SB010 0.28 HUW76_07605 lactate dehydrogenase 0.25 HUW76_05725 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme 0.96 32

Not shown: 10 genomes with orthologs for BWI76_RS12790 only; 18 genomes with orthologs for BWI76_RS08765 only