Conservation of cofitness between BNILDI_13710 and BNILDI_23065 in Escherichia coli ECRC62

58 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli ECRC62 1.0 BNILDI_13710 alkB DNA oxidative demethylase AlkB 1.0 BNILDI_23065 frmA S-(hydroxymethyl)glutathione dehydrogenase 0.73 9
Escherichia coli ECOR27 1.00 NOLOHH_14790 alkB DNA oxidative demethylase AlkB 1.00 NOLOHH_01650 frmA S-(hydroxymethyl)glutathione dehydrogenase low > 75
Escherichia coli ECRC102 0.99 NIAGMN_20980 alkB DNA oxidative demethylase AlkB 1.00 NIAGMN_06795 frmA S-(hydroxymethyl)glutathione dehydrogenase — —
Escherichia coli ECRC98 0.99 JDDGAC_27175 alkB DNA oxidative demethylase AlkB 1.00 JDDGAC_12395 frmA S-(hydroxymethyl)glutathione dehydrogenase low > 86
Escherichia coli ECRC99 0.99 KEDOAH_04970 alkB DNA oxidative demethylase AlkB 1.00 KEDOAH_19230 frmA S-(hydroxymethyl)glutathione dehydrogenase — —
Escherichia coli ECRC100 0.99 OKFHMN_23215 alkB DNA oxidative demethylase AlkB 1.00 OKFHMN_08740 frmA S-(hydroxymethyl)glutathione dehydrogenase low > 80
Escherichia coli ECRC101 0.99 MCAODC_14265 alkB DNA oxidative demethylase AlkB 1.00 MCAODC_27970 frmA S-(hydroxymethyl)glutathione dehydrogenase low > 87
Escherichia coli BW25113 0.98 b2212 alkB oxidative demethylase of N1-methyladenine or N3-methylcytosine DNA lesions (NCBI) 0.99 b0356 frmA alcohol dehydrogenase class III/glutathione-dependent formaldehyde dehydrogenase (NCBI) low > 76
Escherichia coli BL21 0.98 ECD_02139 oxidative demethylase of N1-methyladenine or N3-methylcytosine DNA lesions 1.00 ECD_00310 alcohol dehydrogenase class III; glutathione-dependent formaldehyde dehydrogenase low > 61
Escherichia fergusonii Becca 0.98 EFB2_01643 Alpha-ketoglutarate-dependent dioxygenase AlkB 1.00 EFB2_03694 S-(hydroxymethyl)glutathione dehydrogenase low > 86
Escherichia coli Nissle 1917 0.98 ECOLIN_RS26540 DNA oxidative demethylase AlkB 1.00 ECOLIN_RS02210 S-(hydroxymethyl)glutathione dehydrogenase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.98 OHPLBJKB_01498 Alpha-ketoglutarate-dependent dioxygenase AlkB 1.00 OHPLBJKB_03314 S-(hydroxymethyl)glutathione dehydrogenase low > 73
Escherichia coli ECOR38 0.97 HEPCGN_22480 alkB DNA oxidative demethylase AlkB 1.00 HEPCGN_07365 frmA S-(hydroxymethyl)glutathione dehydrogenase low > 87
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.80 GFF1826 Alkylated DNA repair protein AlkB 0.80 GFF2617 S-(hydroxymethyl)glutathione dehydrogenase (EC 1.1.1.284) low > 78
Enterobacter asburiae PDN3 0.75 EX28DRAFT_0364 Alkylated DNA repair protein 0.83 EX28DRAFT_1257 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 76
Enterobacter sp. TBS_079 0.74 MPMX20_03172 Alpha-ketoglutarate-dependent dioxygenase AlkB 0.83 MPMX20_02209 S-(hydroxymethyl)glutathione dehydrogenase low > 85
Klebsiella michiganensis M5al 0.70 BWI76_RS19890 alpha-ketoglutarate-dependent dioxygenase AlkB 0.84 BWI76_RS13260 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 92
Dickeya dianthicola ME23 0.59 DZA65_RS04440 DNA oxidative demethylase AlkB 0.74 DZA65_RS09655 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 75
Marinobacter adhaerens HP15 0.58 HP15_1028 alkylated DNA repair protein AlkB 0.75 HP15_4017 formaldehyde dehydrogenase (glutathione-dependent) low > 73
Pantoea sp. MT58 0.58 IAI47_06530 DNA oxidative demethylase AlkB 0.75 IAI47_06705 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 76
Dickeya dianthicola 67-19 0.56 HGI48_RS04520 DNA oxidative demethylase AlkB 0.74 HGI48_RS09350 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 71
Dickeya dadantii 3937 0.56 DDA3937_RS04560 DNA oxidative demethylase AlkB 0.74 DDA3937_RS09325 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 74
Pectobacterium carotovorum WPP14 0.56 HER17_RS17090 DNA oxidative demethylase AlkB 0.74 HER17_RS12790 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 75
Rhodopseudomonas palustris CGA009 0.56 TX73_008860 DNA oxidative demethylase AlkB 0.64 TX73_010080 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 86
Rahnella sp. WP5 0.54 EX31_RS03140 DNA oxidative demethylase AlkB 0.74 EX31_RS18715 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 89
Pseudomonas fluorescens FW300-N1B4 0.54 Pf1N1B4_5023 Alkylated DNA repair protein AlkB 0.74 Pf1N1B4_3108 S-(hydroxymethyl)glutathione dehydrogenase (EC 1.1.1.284) low > 87
Pseudomonas sp. RS175 0.54 PFR28_02492 Alpha-ketoglutarate-dependent dioxygenase AlkB 0.73 PFR28_00420 S-(hydroxymethyl)glutathione dehydrogenase low > 88
Rhodanobacter sp. FW510-T8 0.54 OKGIIK_07205 alkB DNA oxidative demethylase AlkB 0.73 OKGIIK_16185 frmA S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 52
Variovorax sp. SCN45 0.53 GFF782 Alpha-ketoglutarate-dependent dioxygenase AlkB (EC 1.14.11.33) 0.60 GFF2941 S-(hydroxymethyl)glutathione dehydrogenase (EC 1.1.1.284) low > 127
Pseudomonas fluorescens FW300-N2E2 0.53 Pf6N2E2_437 Alkylated DNA repair protein AlkB 0.74 Pf6N2E2_3044 S-(hydroxymethyl)glutathione dehydrogenase (EC 1.1.1.284) low > 103
Ralstonia sp. UNC404CL21Col 0.53 ABZR87_RS00890 DNA oxidative demethylase AlkB 0.62 ABZR87_RS08285 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 80
Ralstonia solanacearum PSI07 0.53 RPSI07_RS12045 DNA oxidative demethylase AlkB 0.61 RPSI07_RS20965 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 81
Rhodanobacter denitrificans MT42 0.53 LRK55_RS17960 DNA oxidative demethylase AlkB 0.72 LRK55_RS09575 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 63
Pseudomonas fluorescens GW456-L13 0.53 PfGW456L13_2915 Alkylated DNA repair protein AlkB 0.76 PfGW456L13_3630 S-(hydroxymethyl)glutathione dehydrogenase (EC 1.1.1.284) low > 87
Pseudomonas fluorescens SBW25-INTG 0.52 PFLU_RS14510 DNA oxidative demethylase AlkB 0.75 PFLU_RS06395 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 109
Castellaniella sp019104865 MT123 0.52 ABCV34_RS07710 DNA oxidative demethylase AlkB 0.83 ABCV34_RS09045 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 48
Pseudomonas fluorescens SBW25 0.52 PFLU_RS14510 DNA oxidative demethylase AlkB 0.75 PFLU_RS06395 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 109
Rhodanobacter denitrificans FW104-10B01 0.52 LRK54_RS18105 DNA oxidative demethylase AlkB 0.72 LRK54_RS09935 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 59
Pseudomonas fluorescens FW300-N2E3 0.52 AO353_27010 alpha-ketoglutarate-dependent dioxygenase 0.75 AO353_16580 S-(hydroxymethyl)glutathione dehydrogenase low > 101
Ralstonia solanacearum GMI1000 0.52 RS_RS12875 DNA oxidative demethylase AlkB 0.61 RS_RS17530 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 80
Ralstonia solanacearum IBSBF1503 0.51 RALBFv3_RS05255 DNA oxidative demethylase AlkB 0.62 RALBFv3_RS12345 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 76
Pseudomonas fluorescens FW300-N2C3 0.51 AO356_22760 alpha-ketoglutarate-dependent dioxygenase 0.74 AO356_05920 S-(hydroxymethyl)glutathione dehydrogenase low > 104
Ralstonia solanacearum UW163 0.51 UW163_RS08370 DNA oxidative demethylase AlkB 0.62 UW163_RS01260 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase — —
Pseudomonas simiae WCS417 0.51 PS417_14100 alpha-ketoglutarate-dependent dioxygenase 0.75 PS417_06330 S-(hydroxymethyl)glutathione dehydrogenase low > 88
Herbaspirillum seropedicae SmR1 0.51 HSERO_RS08355 dioxygenase 0.59 HSERO_RS13615 alcohol dehydrogenase low > 78
Pseudomonas syringae pv. syringae B728a 0.51 Psyr_2985 DNA-N1-methyladenine dioxygenase 0.88 Psyr_2956 Zinc-containing alcohol dehydrogenase superfamily low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.51 Psyr_2985 DNA-N1-methyladenine dioxygenase 0.88 Psyr_2956 Zinc-containing alcohol dehydrogenase superfamily low > 86
Acidovorax sp. GW101-3H11 0.50 Ac3H11_2181 Alkylated DNA repair protein AlkB 0.87 Ac3H11_3163 S-(hydroxymethyl)glutathione dehydrogenase (EC 1.1.1.284) low > 79
Variovorax sp. OAS795 0.49 ABID97_RS24835 DNA oxidative demethylase AlkB 0.61 ABID97_RS10235 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 91
Serratia liquefaciens MT49 0.49 IAI46_16945 DNA oxidative demethylase AlkB 0.75 IAI46_07885 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 86
Cupriavidus basilensis FW507-4G11 0.48 RR42_RS23540 alpha-ketoglutarate-dependent dioxygenase 0.61 RR42_RS25775 alcohol dehydrogenase — —
Pseudomonas putida KT2440 0.47 PP_3400 alpha-ketoglutarate- and Fe(II)-dependent dioxygenase 0.75 PP_1616 formaldehyde dehydrogenase, glutathione-dependent low > 96
Rhizobium sp. OAE497 0.35 ABIE40_RS19425 alpha-ketoglutarate-dependent dioxygenase AlkB 0.61 ABIE40_RS09860 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 107
Dinoroseobacter shibae DFL-12 0.33 Dshi_3572 2OG-Fe(II) oxygenase (RefSeq) 0.64 Dshi_0103 Alcohol dehydrogenase class III/S-(hydroxymethyl)glutathione dehydrogenase (RefSeq) low > 64
Caulobacter crescentus NA1000 0.33 CCNA_00009 alkylated DNA repair protein AlkB 0.60 CCNA_02601 glutathione-dependent formaldehyde dehydrogenase low > 66
Bosea sp. OAE506 0.33 ABIE41_RS00230 alpha-ketoglutarate-dependent dioxygenase AlkB 0.61 ABIE41_RS09635 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 77
Caulobacter crescentus NA1000 Δfur 0.33 CCNA_00009 alkylated DNA repair protein AlkB 0.60 CCNA_02601 glutathione-dependent formaldehyde dehydrogenase low > 67
Sinorhizobium meliloti 1021 0.31 SMc02566 alkylated DNA repair protein 0.61 SM_b20170 glutathione-dependent formaldehyde dehydrogenase — —
Brevundimonas sp. GW460-12-10-14-LB2 0.29 A4249_RS13625 alpha-ketoglutarate-dependent dioxygenase AlkB 0.58 A4249_RS00420 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 48

Not shown: 1 genomes with orthologs for BNILDI_13710 only; 26 genomes with orthologs for BNILDI_23065 only