Conservation of cofitness between BBR_RS13710 and BBR_RS20125 in Bifidobacterium breve UCC2003

50 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Bifidobacterium breve UCC2003 1.0 BBR_RS13710 PHP domain-containing protein 1.0 BBR_RS20125 SIR2 family protein 0.32 6
Pseudomonas fluorescens FW300-N2E3 0.21 AO353_18520 phosphoesterase 0.20 AO353_26795 NAD-dependent deacetylase low > 101
Hydrogenophaga sp. GW460-11-11-14-LB1 0.21 GFF114 COG0613, Predicted metal-dependent phosphoesterases (PHP family) 0.18 GFF4837 NAD-dependent protein deacetylase of SIR2 family low > 90
Pseudomonas fluorescens FW300-N2C3 0.20 AO356_18495 phosphoesterase 0.21 AO356_23430 NAD-dependent deacetylase low > 104
Pseudomonas fluorescens FW300-N2E2 0.20 Pf6N2E2_5625 COG0613, Predicted metal-dependent phosphoesterases (PHP family) 0.21 Pf6N2E2_2109 NAD-dependent protein deacetylase of SIR2 family low > 103
Pseudomonas fluorescens SBW25 0.20 PFLU_RS23915 PHP domain-containing protein 0.19 PFLU_RS10600 NAD-dependent protein deacetylase low > 109
Pseudomonas fluorescens SBW25-INTG 0.20 PFLU_RS23915 PHP domain-containing protein 0.19 PFLU_RS10600 NAD-dependent protein deacetylase low > 109
Pseudomonas syringae pv. syringae B728a 0.20 Psyr_3586 Phosphoesterase PHP, N-terminal:PHP, C-terminal 0.17 Psyr_2362 Silent information regulator protein Sir2 low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.20 Psyr_3586 Phosphoesterase PHP, N-terminal:PHP, C-terminal 0.17 Psyr_2362 Silent information regulator protein Sir2
Pseudomonas simiae WCS417 0.20 PS417_22275 phosphoesterase 0.19 PS417_10540 NAD-dependent deacetylase low > 88
Ralstonia solanacearum UW163 0.20 UW163_RS12335 PHP domain-containing protein 0.19 UW163_RS12820 NAD-dependent deacylase
Ralstonia solanacearum IBSBF1503 0.20 RALBFv3_RS14865 PHP domain-containing protein 0.19 RALBFv3_RS15355 NAD-dependent deacylase low > 76
Herbaspirillum seropedicae SmR1 0.19 HSERO_RS16420 phosphoesterase 0.23 HSERO_RS18330 NAD-dependent deacetylase low > 78
Pseudomonas stutzeri RCH2 0.19 Psest_1887 Predicted metal-dependent phosphoesterases (PHP family) 0.19 Psest_2405 NAD-dependent protein deacetylases, SIR2 family low > 67
Pseudomonas putida KT2440 0.19 PP_4500 TrpH family protein 0.21 PP_5402 deacetylase of acetyl-CoA synthetase, NAD-dependent low > 96
Ralstonia solanacearum GMI1000 0.19 RS_RS05675 PHP domain-containing protein 0.18 RS_RS06165 NAD-dependent deacylase low > 80
Paraburkholderia graminis OAS925 0.18 ABIE53_002754 putative metal-dependent phosphoesterase TrpH 0.22 ABIE53_005120 NAD-dependent SIR2 family protein deacetylase low > 113
Klebsiella michiganensis M5al 0.18 BWI76_RS11865 phosphatase 0.16 BWI76_RS11230 NAD-dependent deacylase low > 92
Paraburkholderia bryophila 376MFSha3.1 0.18 H281DRAFT_00504 hypothetical protein 0.22 H281DRAFT_03044 NAD-dependent protein deacetylase, SIR2 family
Burkholderia phytofirmans PsJN 0.18 BPHYT_RS12640 phosphoesterase 0.22 BPHYT_RS29640 NAD-dependent deacetylase low > 109
Ralstonia solanacearum PSI07 0.18 RPSI07_RS18495 PHP domain-containing protein 0.19 RPSI07_RS18020 NAD-dependent deacylase low > 81
Dechlorosoma suillum PS 0.18 Dsui_2731 putative metal-dependent phosphoesterase, PHP family 0.18 Dsui_2796 NAD-dependent protein deacetylase, SIR2 family 0.59 11
Cupriavidus basilensis FW507-4G11 0.18 RR42_RS06225 phosphoesterase 0.25 RR42_RS27705 NAD-dependent deacetylase low > 128
Vibrio cholerae E7946 ATCC 55056 0.18 CSW01_05960 PHP domain-containing protein 0.16 CSW01_07575 NAD-dependent protein deacylase low > 62
Pseudomonas sp. S08-1 0.17 OH686_20795 Predicted metal-dependent (PHP family) 0.20 OH686_06015 NAD-dependent protein deacetylase of SIR2 family low > 80
Ralstonia sp. UNC404CL21Col 0.17 ABZR87_RS10520 3',5'-nucleoside bisphosphate phosphatase 0.20 ABZR87_RS10995 NAD-dependent deacylase low > 80
Acidovorax sp. GW101-3H11 0.17 Ac3H11_1752 COG0613, Predicted metal-dependent phosphoesterases (PHP family) 0.20 Ac3H11_4140 NAD-dependent protein deacetylase of SIR2 family low > 79
Paraburkholderia sabiae LMG 24235 0.16 QEN71_RS05915 3',5'-nucleoside bisphosphate phosphatase 0.23 QEN71_RS20510 NAD-dependent protein deacetylase low > 153
Serratia liquefaciens MT49 0.16 IAI46_14015 PHP domain-containing protein 0.17 IAI46_10355 NAD-dependent protein deacylase low > 86
Kangiella aquimarina DSM 16071 0.16 B158DRAFT_2304 Predicted metal-dependent phosphoesterases (PHP family) 0.20 B158DRAFT_0796 NAD-dependent protein deacetylases, SIR2 family low > 40
Pectobacterium carotovorum WPP14 0.16 HER17_RS10910 PHP domain-containing protein 0.17 HER17_RS08800 NAD-dependent protein deacylase low > 75
Variovorax sp. SCN45 0.16 GFF5791 FIG00031715: Predicted metal-dependent phosphoesterases (PHP family) 0.17 GFF5049 NAD-dependent protein deacetylase of SIR2 family low > 127
Escherichia coli ECRC99 0.15 KEDOAH_26105 yciV 5'-3' exoribonuclease 0.18 KEDOAH_24315 cobB NAD-dependent protein deacylase
Escherichia coli ECRC98 0.15 JDDGAC_05190 yciV 5'-3' exoribonuclease 0.18 JDDGAC_07100 cobB NAD-dependent protein deacylase low > 86
Escherichia coli ECRC100 0.15 OKFHMN_02645 yciV 5'-3' exoribonuclease 0.18 OKFHMN_03440 cobB NAD-dependent protein deacylase low > 80
Escherichia coli ECRC101 0.15 MCAODC_15620 yciV 5'-3' exoribonuclease 0.18 MCAODC_22800 cobB NAD-dependent protein deacylase low > 87
Escherichia coli ECRC102 0.15 NIAGMN_26815 yciV 5'-3' exoribonuclease 0.18 NIAGMN_24390 cobB NAD-dependent protein deacylase
Escherichia coli BW25113 0.15 b1266 yciV hypothetical protein (NCBI) 0.18 b1120 cobB deacetylase of acs and cheY, regulates chemotaxis (NCBI) low > 76
Escherichia coli HS(pFamp)R (ATCC 700891) 0.15 OHPLBJKB_02418 '5'-3' exoribonuclease' transl_table=11 0.18 OHPLBJKB_02546 NAD-dependent protein deacylase low > 73
Escherichia coli ECOR27 0.15 NOLOHH_20305 yciV 5'-3' exoribonuclease 0.18 NOLOHH_20965 cobB NAD-dependent protein deacylase low > 75
Escherichia coli ECRC62 0.15 BNILDI_18455 yciV 5'-3' exoribonuclease 0.18 BNILDI_19130 cobB NAD-dependent protein deacylase low > 75
Escherichia coli BL21 0.15 ECD_01240 PHP domain protein 0.18 ECD_01118 deacetylase of acs and cheY, chemotaxis regulator low > 61
Escherichia fergusonii Becca 0.15 EFB2_02661 5'-3' exoribonuclease 0.18 EFB2_02855 NAD-dependent protein deacylase low > 86
Escherichia coli Nissle 1917 0.15 ECOLIN_RS07620 RNase AM 0.18 ECOLIN_RS06455 Sir2 family NAD+-dependent deacetylase
Marinobacter adhaerens HP15 0.15 HP15_2224 PHP C-terminal domain protein 0.20 HP15_2625 silent information regulator protein Sir2 low > 73
Escherichia coli ECOR38 0.15 HEPCGN_25545 yciV 5'-3' exoribonuclease 0.18 HEPCGN_24045 cobB NAD-dependent protein deacylase low > 87
Shewanella amazonensis SB2B 0.14 Sama_2128 PHP-like protein (RefSeq) 0.17 Sama_1435 NAD-dependent deacetylase (RefSeq) low > 62
Shewanella loihica PV-4 0.14 Shew_2250 phosphotransferase domain-containing protein (RefSeq) 0.18 Shew_1662 NAD-dependent deacetylase (RefSeq) low > 60
Erwinia tracheiphila SCR3 0.13 LU632_RS12750 PHP domain-containing protein 0.15 LU632_RS14640 cobB NAD-dependent protein deacylase low > 74
Shewanella sp. ANA-3 0.13 Shewana3_1521 phosphotransferase domain-containing protein (RefSeq) 0.17 Shewana3_1717 NAD-dependent deacetylase (RefSeq)
Shewanella oneidensis MR-1 0.13 SO3017 TrpH family protein (NCBI ptt file) 0.17 SO1938 cobB cobB protein (NCBI ptt file) low > 76

Not shown: 18 genomes with orthologs for BBR_RS13710 only; 26 genomes with orthologs for BBR_RS20125 only