Conservation of cofitness between ABZR87_RS17475 and ABZR87_RS17460 in Ralstonia sp. UNC404CL21Col

51 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Ralstonia sp. UNC404CL21Col 1.0 ABZR87_RS17475 3-hydroxyisobutyrate dehydrogenase 1.0 ABZR87_RS17460 acyl-CoA dehydrogenase 0.66 4
Ralstonia solanacearum PSI07 0.81 RPSI07_RS02325 3-hydroxyisobutyrate dehydrogenase 0.93 RPSI07_RS02340 acyl-CoA dehydrogenase low > 81
Ralstonia solanacearum UW163 0.81 UW163_RS18760 3-hydroxyisobutyrate dehydrogenase 0.91 UW163_RS18775 acyl-CoA dehydrogenase — —
Ralstonia solanacearum IBSBF1503 0.81 RALBFv3_RS20415 3-hydroxyisobutyrate dehydrogenase 0.91 RALBFv3_RS20400 acyl-CoA dehydrogenase low > 76
Burkholderia phytofirmans PsJN 0.79 BPHYT_RS28025 3-hydroxyisobutyrate dehydrogenase 0.90 BPHYT_RS28040 acyl-CoA dehydrogenase low > 109
Paraburkholderia sabiae LMG 24235 0.78 QEN71_RS12390 3-hydroxyisobutyrate dehydrogenase 0.88 QEN71_RS12405 acyl-CoA dehydrogenase 0.38 55
Ralstonia solanacearum GMI1000 0.78 RS_RS20225 3-hydroxyisobutyrate dehydrogenase 0.90 RS_RS20240 acyl-CoA dehydrogenase low > 80
Paraburkholderia bryophila 376MFSha3.1 0.76 H281DRAFT_01201 3-hydroxyisobutyrate dehydrogenase 0.86 H281DRAFT_01204 hypothetical protein 0.38 18
Paraburkholderia graminis OAS925 0.75 ABIE53_005735 3-hydroxyisobutyrate dehydrogenase 0.86 ABIE53_005731 alkylation response protein AidB-like acyl-CoA dehydrogenase 0.33 5
Cupriavidus basilensis FW507-4G11 0.67 RR42_RS28555 3-hydroxyisobutyrate dehydrogenase 0.76 RR42_RS28565 acyl-CoA dehydrogenase — —
Pseudomonas fluorescens SBW25-INTG 0.67 PFLU_RS25535 3-hydroxyisobutyrate dehydrogenase 0.72 PFLU_RS14780 acyl-CoA dehydrogenase 0.49 9
Pseudomonas fluorescens SBW25 0.67 PFLU_RS25535 3-hydroxyisobutyrate dehydrogenase 0.72 PFLU_RS14780 acyl-CoA dehydrogenase low > 109
Pseudomonas simiae WCS417 0.66 PS417_23720 3-hydroxyisobutyrate dehydrogenase 0.71 PS417_13840 isobutyryl-CoA dehydrogenase (EC 1.3.8.5) (from data) — —
Pseudomonas fluorescens FW300-N2C3 0.65 AO356_07865 3-hydroxyisobutyrate dehydrogenase 0.71 AO356_26365 acyl-CoA dehydrogenase low > 104
Pseudomonas fluorescens FW300-N2E2 0.64 Pf6N2E2_3451 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) 0.71 Pf6N2E2_1148 Butyryl-CoA dehydrogenase (EC 1.3.99.2) low > 103
Pseudomonas syringae pv. syringae B728a ΔmexB 0.64 Psyr_0690 3-hydroxyisobutyrate dehydrogenase 0.68 Psyr_1769 Acyl-CoA dehydrogenase, C-terminal:Acyl-CoA dehydrogenase, central region:Acyl-CoA dehydrogenase, N-terminal low > 86
Pseudomonas syringae pv. syringae B728a 0.64 Psyr_0690 3-hydroxyisobutyrate dehydrogenase 0.68 Psyr_1769 Acyl-CoA dehydrogenase, C-terminal:Acyl-CoA dehydrogenase, central region:Acyl-CoA dehydrogenase, N-terminal low > 86
Pseudomonas sp. RS175 0.64 PFR28_00014 3-hydroxyisobutyrate dehydrogenase 0.70 PFR28_01886 Acyl-CoA dehydrogenase 0.84 3
Pseudomonas putida KT2440 0.63 PP_4666 3-hydroxyisobutyrate dehydrogenase 0.72 PP_3492 isobutyryl-CoA dehydrogenase (EC 1.3.8.5) (from data) 0.50 6
Pseudomonas fluorescens FW300-N1B4 0.63 Pf1N1B4_1228 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) 0.72 Pf1N1B4_4789 Butyryl-CoA dehydrogenase (EC 1.3.99.2) — —
Pseudomonas fluorescens GW456-L13 0.63 PfGW456L13_5145 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) (from data) 0.71 PfGW456L13_2985 isobutyryl-CoA dehydrogenase (EC 1.3.8.5) (from data) 0.79 7
Pseudomonas fluorescens FW300-N2E3 0.63 AO353_05985 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) (from data) 0.71 AO353_25670 isobutyryl-CoA dehydrogenase (EC 1.3.8.5) (from data) 0.53 6
Pseudomonas stutzeri RCH2 0.62 Psest_2438 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) (from data) 0.72 Psest_2440 isobutyryl-CoA dehydrogenase (EC 1.3.8.5) (from data) 0.31 9
Acinetobacter radioresistens SK82 0.59 MPMX26_01549 3-hydroxyisobutyrate dehydrogenase 0.63 MPMX26_01547 Acyl-CoA dehydrogenase — —
Xanthomonas campestris pv. campestris strain 8004 0.50 Xcc-8004.3685.1 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) 0.45 Xcc-8004.3378.1 hypothetical protein low > 74
Shewanella oneidensis MR-1 0.48 SO1682 mmsB 3-hydroxyisobutyrate dehydrogenase (NCBI ptt file) 0.39 SO1679 2-methylbutanoyl-CoA dehydrogenase (EC 1.3.8.5) (from data) 0.59 5
Pseudomonas sp. S08-1 0.45 OH686_05885 3-hydroxyisobutyrate dehydrogenase 0.63 OH686_00875 Acyl-CoA dehydrogenase, short-chain specific low > 80
Rhizobium sp. OAE497 0.44 ABIE40_RS24830 3-hydroxyisobutyrate dehydrogenase 0.61 ABIE40_RS23185 acyl-CoA dehydrogenase family protein low > 107
Shewanella amazonensis SB2B 0.44 Sama_1380 3-hydroxyisobutyrate dehydrogenase (RefSeq) 0.39 Sama_1377 butyryl-CoA dehydrogenase (RefSeq) low > 62
Shewanella loihica PV-4 0.43 Shew_1672 3-hydroxyisobutyrate dehydrogenase (RefSeq) 0.37 Shew_1669 butyryl-CoA dehydrogenase (RefSeq) 0.29 11
Agrobacterium fabrum C58 0.43 Atu4129 3-hydroxyisobutyrate dehydrogenase 0.63 Atu3474 acyl-CoA dehydrogenase low > 89
Sinorhizobium meliloti 1021 0.42 SM_b20751 3-hydroxyisobutyrate dehydrogenase 0.37 SMa1400 acyl-CoA dehydrogenase low > 103
Rhodopseudomonas palustris CGA009 0.38 TX73_017835 3-hydroxyisobutyrate dehydrogenase 0.58 TX73_011920 acyl-CoA dehydrogenase family protein low > 86
Rhodospirillum rubrum S1H 0.38 Rru_A1833 3-hydroxyisobutyrate dehydrogenase (NCBI) 0.38 Rru_A1835 Butyryl-CoA dehydrogenase (NCBI) low > 58
Alteromonas macleodii MIT1002 0.36 MIT1002_03327 3-hydroxyisobutyrate dehydrogenase 0.39 MIT1002_01978 Acyl-CoA dehydrogenase 0.75 36
Dinoroseobacter shibae DFL-12 0.36 Dshi_1752 3-hydroxyisobutyrate dehydrogenase (RefSeq) 0.35 Dshi_1750 acyl-CoA dehydrogenase domain protein (RefSeq) low > 64
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.31 GFF2237 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) 0.25 GFF3546 Crotonobetainyl-CoA dehydrogenase (EC 1.3.99.-) low > 78
Escherichia coli BW25113 0.30 b3882 yihU predicted oxidoreductase with NAD(P)-binding Rossmann-fold domain (NCBI) 0.24 b1695 b1695 putative oxidoreductase (VIMSS) low > 76
Escherichia coli ECRC62 0.30 BNILDI_05370 yihU sulfolactaldehyde 3-reductase 0.24 BNILDI_16495 ydiO acyl-CoA dehydrogenase low > 75
Escherichia coli ECOR27 0.30 NOLOHH_06160 yihU sulfolactaldehyde 3-reductase 0.24 NOLOHH_17705 ydiO acyl-CoA dehydrogenase low > 75
Escherichia coli ECOR38 0.30 HEPCGN_12660 yihU sulfolactaldehyde 3-reductase 0.24 HEPCGN_05570 ydiO acyl-CoA dehydrogenase low > 87
Escherichia coli ECRC100 0.29 OKFHMN_14025 yihU sulfolactaldehyde 3-reductase 0.24 OKFHMN_27185 ydiO acyl-CoA dehydrogenase — —
Escherichia coli ECRC101 0.29 MCAODC_04525 yihU sulfolactaldehyde 3-reductase 0.24 MCAODC_18225 ydiO acyl-CoA dehydrogenase low > 87
Escherichia coli ECRC102 0.29 NIAGMN_11780 yihU sulfolactaldehyde 3-reductase 0.24 NIAGMN_00880 ydiO acyl-CoA dehydrogenase — —
Escherichia coli ECRC98 0.29 JDDGAC_17650 yihU sulfolactaldehyde 3-reductase 0.24 JDDGAC_01760 ydiO acyl-CoA dehydrogenase low > 86
Escherichia coli ECRC99 0.29 KEDOAH_14130 yihU sulfolactaldehyde 3-reductase 0.24 KEDOAH_00925 ydiO acyl-CoA dehydrogenase — —
Escherichia coli BL21 0.29 ECD_03767 3-sulfolactaldehyde (SLA) reductase, NADH-dependent; gamma-hydroxybutyrate dehydrogenase, NADH-dependent 0.24 ECD_01664 putative acyl-CoA dehydrogenase low > 61
Escherichia fergusonii Becca 0.27 EFB2_04739 3-sulfolactaldehyde reductase 0.24 EFB2_01909 putative acyl-CoA dehydrogenase fadE25 low > 86
Dyella japonica UNC79MFTsu3.2 0.23 ABZR86_RS00420 NAD(P)-dependent oxidoreductase 0.47 ABZR86_RS07575 acyl-CoA dehydrogenase family protein low > 74
Rhodanobacter denitrificans MT42 0.20 LRK55_RS14400 NAD(P)-dependent oxidoreductase 0.46 LRK55_RS01880 acyl-CoA dehydrogenase family protein low > 63
Rhodanobacter denitrificans FW104-10B01 0.20 LRK54_RS14685 NAD(P)-dependent oxidoreductase 0.46 LRK54_RS02105 acyl-CoA dehydrogenase family protein low > 59
Rhodanobacter sp. FW510-T8 0.19 OKGIIK_03510 mmsB 3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase 0.46 OKGIIK_09175 caiA acyl-CoA dehydrogenase low > 52

Not shown: 20 genomes with orthologs for ABZR87_RS17475 only; 9 genomes with orthologs for ABZR87_RS17460 only