Conservation of cofitness between ABZR87_RS04525 and ABZR87_RS04235 in Ralstonia sp. UNC404CL21Col

60 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Ralstonia sp. UNC404CL21Col 1.0 ABZR87_RS04525 sensor histidine kinase KdpD 1.0 ABZR87_RS04235 heavy metal translocating P-type ATPase 0.39 15
Ralstonia solanacearum PSI07 0.88 RPSI07_RS08140 sensor histidine kinase KdpD 0.83 RPSI07_RS08310 copper-translocating P-type ATPase low > 81
Ralstonia solanacearum UW163 0.88 UW163_RS04465 sensor histidine kinase KdpD 0.83 UW163_RS04650 copper-translocating P-type ATPase
Ralstonia solanacearum IBSBF1503 0.88 RALBFv3_RS09130 sensor histidine kinase KdpD 0.83 RALBFv3_RS08960 copper-translocating P-type ATPase low > 76
Ralstonia solanacearum GMI1000 0.88 RS_RS16960 sensor histidine kinase KdpD 0.83 RS_RS16775 copper-translocating P-type ATPase low > 80
Cupriavidus basilensis FW507-4G11 0.59 RR42_RS00495 histidine kinase 0.55 RR42_RS20305 metal ABC transporter ATPase low > 128
Pseudomonas fluorescens FW300-N2E3 0.48 AO353_28955 sensor protein KdpD 0.55 AO353_06155 copper-transporting ATPase low > 101
Dechlorosoma suillum PS 0.45 Dsui_0272 osmosensitive K+ channel histidine kinase 0.52 Dsui_1065 copper/silver-translocating P-type ATPase low > 51
Acidovorax sp. GW101-3H11 0.44 Ac3H11_2408 Osmosensitive K+ channel histidine kinase KdpD (EC 2.7.3.-) 0.58 Ac3H11_4218 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) low > 79
Paraburkholderia sabiae LMG 24235 0.43 QEN71_RS24345 DUF4118 domain-containing protein 0.57 QEN71_RS17330 heavy metal translocating P-type ATPase low > 153
Paraburkholderia bryophila 376MFSha3.1 0.43 H281DRAFT_04532 two-component system, OmpR family, sensor histidine kinase KdpD 0.55 H281DRAFT_03512 Cu+-exporting ATPase low > 103
Paraburkholderia graminis OAS925 0.43 ABIE53_001556 two-component system sensor histidine kinase KdpD 0.55 ABIE53_004745 Cu+-exporting ATPase low > 113
Herbaspirillum seropedicae SmR1 0.42 HSERO_RS18855 sensor protein KdpD 0.57 HSERO_RS08020 heavy metal translocating P-type ATPase 0.28 20
Burkholderia phytofirmans PsJN 0.42 BPHYT_RS06460 histidine kinase 0.55 BPHYT_RS34125 heavy metal translocating P-type ATPase low > 109
Variovorax sp. SCN45 0.42 GFF3520 Osmosensitive K+ channel histidine kinase KdpD 0.52 GFF3317 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) low > 127
Variovorax sp. OAS795 0.41 ABID97_RS01010 DUF4118 domain-containing protein 0.52 ABID97_RS02825 heavy metal translocating P-type ATPase low > 91
Serratia liquefaciens MT49 0.41 IAI46_06165 two-component system sensor histidine kinase KdbD 0.39 IAI46_13395 copper-translocating P-type ATPase low > 86
Rahnella sp. WP5 0.40 EX31_RS23335 two-component system sensor histidine kinase KdbD 0.34 EX31_RS22575 copper-exporting P-type ATPase CopA low > 89
Enterobacter asburiae PDN3 0.40 EX28DRAFT_2283 Osmosensitive K+ channel histidine kinase 0.35 EX28DRAFT_2474 copper-(or silver)-translocating P-type ATPase low > 76
Enterobacter sp. TBS_079 0.40 MPMX20_01338 Sensor protein KdpD 0.34 MPMX20_01084 Copper-exporting P-type ATPase low > 85
Pectobacterium carotovorum WPP14 0.39 HER17_RS15045 two-component system sensor histidine kinase KdpD 0.35 HER17_RS15625 copper-exporting P-type ATPase CopA low > 75
Escherichia coli ECRC62 0.39 BNILDI_21460 kdpD two-component system sensor histidine kinase KdpD 0.34 BNILDI_22435 copA copper-exporting P-type ATPase CopA low > 75
Escherichia coli ECOR27 0.39 NOLOHH_23455 kdpD two-component system sensor histidine kinase KdpD 0.34 NOLOHH_01015 copA copper-exporting P-type ATPase CopA low > 75
Escherichia coli Nissle 1917 0.39 ECOLIN_RS03755 two-component system sensor histidine kinase KdpD 0.34 ECOLIN_RS02865 copper-exporting P-type ATPase CopA low > 55
Escherichia coli HS(pFamp)R (ATCC 700891) 0.39 OHPLBJKB_03022 Sensor protein KdpD 0.34 OHPLBJKB_03190 Copper-exporting P-type ATPase low > 73
Escherichia coli ECOR38 0.39 HEPCGN_01160 kdpD two-component system sensor histidine kinase KdpD 0.35 HEPCGN_06710 copA copper-exporting P-type ATPase CopA low > 87
Escherichia coli ECRC99 0.39 KEDOAH_20895 kdpD two-component system sensor histidine kinase KdpD 0.34 KEDOAH_19895 copA copper-exporting P-type ATPase CopA
Escherichia coli ECRC100 0.39 OKFHMN_07075 kdpD two-component system sensor histidine kinase KdpD 0.34 OKFHMN_08075 copA copper-exporting P-type ATPase CopA low > 80
Escherichia coli ECRC101 0.39 MCAODC_26290 kdpD two-component system sensor histidine kinase KdpD 0.34 MCAODC_27295 copA copper-exporting P-type ATPase CopA low > 87
Escherichia coli ECRC102 0.39 NIAGMN_05130 kdpD two-component system sensor histidine kinase KdpD 0.34 NIAGMN_06125 copA copper-exporting P-type ATPase CopA
Escherichia fergusonii Becca 0.39 EFB2_03401 Sensor protein KdpD 0.34 EFB2_03575 Copper-exporting P-type ATPase low > 86
Escherichia coli BL21 0.39 ECD_00652 fused sensory histidine kinase in two-component regulatory system with KdpE: signal sensing protein 0.34 ECD_00435 copper transporter 0.46 41
Escherichia coli ECRC98 0.39 JDDGAC_10725 kdpD two-component system sensor histidine kinase KdpD 0.34 JDDGAC_11720 copA copper-exporting P-type ATPase CopA low > 86
Escherichia coli BW25113 0.39 b0695 kdpD fused sensory histidine kinase in two-component regulatory system with KdpE: signal sensing protein (NCBI) 0.34 b0484 copA copper transporter (NCBI) low > 76
Klebsiella michiganensis M5al 0.39 BWI76_RS08305 two-component sensor histidine kinase 0.34 BWI76_RS06905 Cu+ exporting ATPase low > 92
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.39 GFF4607 Osmosensitive K+ channel histidine kinase KdpD (EC 2.7.3.-) 0.37 GFF4248 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) low > 78
Pantoea sp. MT58 0.38 IAI47_01250 two-component system sensor histidine kinase KdbD 0.36 IAI47_14400 copper-exporting P-type ATPase CopA low > 76
Erwinia tracheiphila SCR3 0.38 LU632_RS00800 kdpD two-component system sensor histidine kinase KdpD 0.32 LU632_RS15300 copA copper-exporting P-type ATPase CopA low > 74
Azospirillum sp. SherDot2 0.29 MPMX19_03748 Sensor protein KdpD 0.52 MPMX19_04397 Copper-exporting P-type ATPase low > 112
Agrobacterium fabrum C58 0.29 Atu3787 two component sensor kinase 0.38 Atu1195 heavy-metal transporting P-type ATPase low > 89
Rhodospirillum rubrum S1H 0.29 Rru_A1158 Osmosensitive K+ channel Signal Transduction Histidine Kinase (NCBI) 0.45 Rru_A1894 heavy metal translocating P-type ATPase (NCBI) low > 58
Magnetospirillum magneticum AMB-1 0.28 AMB_RS09655 sensor histidine kinase KdpD 0.43 AMB_RS09145 copper-translocating P-type ATPase
Bosea sp. OAE506 0.27 ABIE41_RS24230 sensor histidine kinase KdpD 0.36 ABIE41_RS14220 heavy metal translocating P-type ATPase low > 77
Hydrogenophaga sp. GW460-11-11-14-LB1 0.26 GFF4474 Osmosensitive K+ channel histidine kinase KdpD (EC 2.7.3.-) 0.51 GFF2052 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) low > 90
Pseudomonas putida KT2440 0.26 PP_4158 sensor protein 0.54 PP_0586 cadmium translocating P-type ATPase low > 96
Pseudomonas fluorescens FW300-N2E2 0.26 Pf6N2E2_2491 Osmosensitive K+ channel histidine kinase KdpD (EC 2.7.3.-) 0.56 Pf6N2E2_3487 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) low > 103
Pseudomonas fluorescens FW300-N1B4 0.25 Pf1N1B4_312 Osmosensitive K+ channel histidine kinase KdpD (EC 2.7.3.-) 0.54 Pf1N1B4_1262 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) low > 87
Pseudomonas fluorescens GW456-L13 0.25 PfGW456L13_2204 Osmosensitive K+ channel histidine kinase KdpD (EC 2.7.3.-) 0.55 PfGW456L13_24 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) low > 87
Pseudomonas sp. RS175 0.25 PFR28_00942 Sensor protein KdpD 0.56 PFR28_05244 Copper-exporting P-type ATPase low > 88
Dyella japonica UNC79MFTsu3.2 0.25 ABZR86_RS13210 sensor histidine kinase KdpD 0.34 ABZR86_RS01750 heavy metal translocating P-type ATPase low > 74
Pseudomonas simiae WCS417 0.25 PS417_08300 histidine kinase 0.55 PS417_03160 metal ABC transporter ATPase 0.16 44
Sinorhizobium meliloti 1021 0.25 SMa2327 sensor protein 0.37 SMa1013 ATPase P low > 103
Pseudomonas fluorescens FW300-N2C3 0.25 AO356_03300 histidine kinase 0.55 AO356_08065 copper-transporting ATPase low > 104
Pseudomonas fluorescens SBW25 0.25 PFLU_RS08240 sensor histidine kinase KdpD 0.54 PFLU_RS03240 copper-translocating P-type ATPase low > 109
Pseudomonas fluorescens SBW25-INTG 0.25 PFLU_RS08240 sensor histidine kinase KdpD 0.54 PFLU_RS03240 copper-translocating P-type ATPase low > 109
Pseudomonas syringae pv. syringae B728a ΔmexB 0.25 Psyr_2050 ATP-binding region, ATPase-like:Histidine kinase A, N-terminal:Osmosensitive K+ channel His kinase sensor:UspA 0.55 Psyr_0654 Copper-translocating P-type ATPase:Heavy metal translocating P-type ATPase low > 86
Pseudomonas syringae pv. syringae B728a 0.25 Psyr_2050 ATP-binding region, ATPase-like:Histidine kinase A, N-terminal:Osmosensitive K+ channel His kinase sensor:UspA 0.55 Psyr_0654 Copper-translocating P-type ATPase:Heavy metal translocating P-type ATPase low > 86
Brevundimonas sp. GW460-12-10-14-LB2 0.23 A4249_RS15630 sensor histidine kinase KdpD 0.33 A4249_RS03270 heavy metal translocating P-type ATPase low > 48
Sphingomonas koreensis DSMZ 15582 0.23 Ga0059261_3881 Osmosensitive K+ channel histidine kinase 0.36 Ga0059261_1162 copper-(or silver)-translocating P-type ATPase low > 68
Acinetobacter radioresistens SK82 0.21 MPMX26_02241 Sensor protein KdpD 0.38 MPMX26_01948 Copper-transporting P-type ATPase
Pseudomonas sp. S08-1 0.11 OH686_01890 Osmosensitive K+ channel histidine kinase KdpD 0.56 OH686_07395 copper-translocating P-type ATPase low > 80

Not shown: 9 genomes with orthologs for ABZR87_RS04525 only; 30 genomes with orthologs for ABZR87_RS04235 only