Conservation of cofitness between A4249_RS00170 and A4249_RS05505 in Brevundimonas sp. GW460-12-10-14-LB2

47 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Brevundimonas sp. GW460-12-10-14-LB2 1.0 A4249_RS00170 TetR/AcrR family transcriptional regulator 1.0 A4249_RS05505 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase 0.66 10
Azospirillum sp. SherDot2 0.58 MPMX19_04477 hypothetical protein 0.49 MPMX19_00838 GTP pyrophosphokinase rsh low > 112
Agrobacterium fabrum C58 0.52 Atu5443 TetR family transcriptional regulator 0.43 Atu1030 GTP pyrophosphohydrolase/synthetase, RelA/SpoT family 0.25 7
Klebsiella michiganensis M5al 0.46 BWI76_RS14005 TetR family transcriptional regulator 0.34 BWI76_RS27430 (p)ppGpp synthetase low > 92
Enterobacter sp. TBS_079 0.37 MPMX20_02562 hypothetical protein 0.34 MPMX20_00086 Bifunctional (p)ppGpp synthase/hydrolase SpoT low > 85
Pectobacterium carotovorum WPP14 0.36 HER17_RS14315 TetR/AcrR family transcriptional regulator 0.34 HER17_RS21385 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase low > 75
Dickeya dianthicola ME23 0.35 DZA65_RS04665 TetR/AcrR family transcriptional regulator 0.33 DZA65_RS22150 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase
Pseudomonas fluorescens FW300-N2C3 0.35 AO356_28600 TetR family transcriptional regulator 0.32 AO356_12480 (p)ppGpp synthetase
Dickeya dadantii 3937 0.35 DDA3937_RS02915 TetR/AcrR family transcriptional regulator 0.33 DDA3937_RS00180 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase
Dickeya dianthicola 67-19 0.35 HGI48_RS02880 TetR/AcrR family transcriptional regulator 0.33 HGI48_RS21180 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase
Rahnella sp. WP5 0.35 EX31_RS11065 TetR/AcrR family transcriptional regulator 0.35 EX31_RS15810 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase low > 89
Paraburkholderia graminis OAS925 0.34 ABIE53_006306 TetR/AcrR family transcriptional repressor of nem operon 0.33 ABIE53_003230 guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 113
Pseudomonas fluorescens FW300-N2E2 0.34 Pf6N2E2_1652 Transcriptional regulator, TetR family 0.32 Pf6N2E2_4361 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)
Pantoea sp. MT58 0.34 IAI47_20850 TetR/AcrR family transcriptional regulator 0.34 IAI47_00510 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase low > 76
Paraburkholderia bryophila 376MFSha3.1 0.33 H281DRAFT_06516 transcriptional regulator, TetR family 0.33 H281DRAFT_04004 (p)ppGpp synthetase I, SpoT/RelA
Pseudomonas syringae pv. syringae B728a 0.33 Psyr_2719 transcriptional regulator, TetR family 0.32 Psyr_0209 RelA/SpoT protein
Pseudomonas fluorescens FW300-N1B4 0.33 Pf1N1B4_4195 Transcriptional regulator, TetR family 0.32 Pf1N1B4_2113 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)
Pseudomonas sp. RS175 0.33 PFR28_02353 hypothetical protein 0.32 PFR28_04424 Bifunctional (p)ppGpp synthase/hydrolase SpoT
Pseudomonas syringae pv. syringae B728a ΔmexB 0.33 Psyr_2719 transcriptional regulator, TetR family 0.32 Psyr_0209 RelA/SpoT protein
Cupriavidus basilensis FW507-4G11 0.32 RR42_RS25615 TetR family transcriptional regulator 0.35 RR42_RS04920 guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase
Pseudomonas fluorescens FW300-N2E3 0.32 AO353_28425 TetR family transcriptional regulator 0.32 AO353_09280 (p)ppGpp synthetase
Pseudomonas fluorescens SBW25-INTG 0.32 PFLU_RS16255 TetR/AcrR family transcriptional regulator 0.32 PFLU_RS29510 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase
Pseudomonas fluorescens SBW25 0.32 PFLU_RS16255 TetR/AcrR family transcriptional regulator 0.32 PFLU_RS29510 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase
Sinorhizobium meliloti 1021 0.31 SMa1887 transcriptional regulator 0.42 SMc02659 GTP pyrophosphokinase (ATP:GTP 3'-pyrophosphotransferase) protein
Pseudomonas simiae WCS417 0.31 PS417_17400 TetR family transcriptional regulator 0.32 PS417_27830 (p)ppGpp synthetase
Rhodopseudomonas palustris CGA009 0.31 TX73_017865 TetR/AcrR family transcriptional regulator 0.45 TX73_013955 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 86
Serratia liquefaciens MT49 0.31 IAI46_04665 TetR/AcrR family transcriptional regulator 0.33 IAI46_24895 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase low > 86
Ralstonia solanacearum UW163 0.31 UW163_RS18295 TetR/AcrR family transcriptional regulator 0.34 UW163_RS10410 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase
Ralstonia solanacearum IBSBF1503 0.31 RALBFv3_RS16940 TetR/AcrR family transcriptional regulator 0.34 RALBFv3_RS03315 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 76
Azospirillum brasilense Sp245 0.31 AZOBR_RS28170 TetR family transcriptional regulator 0.51 AZOBR_RS22045 GTP pyrophosphokinase
Variovorax sp. OAS795 0.30 ABID97_RS22750 TetR/AcrR family transcriptional regulator 0.31 ABID97_RS23670 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase
Ralstonia solanacearum PSI07 0.29 RPSI07_RS04030 TetR/AcrR family transcriptional regulator 0.34 RPSI07_RS13870 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 81
Rhizobium sp. OAE497 0.29 ABIE40_RS08225 TetR/AcrR family transcriptional regulator 0.42 ABIE40_RS06050 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 107
Dyella japonica UNC79MFTsu3.2 0.28 ABZR86_RS00620 TetR/AcrR family transcriptional regulator 0.31 ABZR86_RS11850 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase
Burkholderia phytofirmans PsJN 0.28 BPHYT_RS21595 TetR family transcriptional regulator 0.33 BPHYT_RS15305 guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 109
Variovorax sp. SCN45 0.27 GFF6085 Transcriptional regulator, AcrR family 0.31 GFF2375 Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) / GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II
Pseudomonas fluorescens GW456-L13 0.27 PfGW456L13_3496 Transcriptional regulator, TetR family 0.32 PfGW456L13_780 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)
Hydrogenophaga sp. GW460-11-11-14-LB1 0.27 GFF2131 Transcriptional regulator, TetR family 0.31 GFF1034 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)
Paraburkholderia sabiae LMG 24235 0.27 QEN71_RS20830 TetR family transcriptional regulator 0.33 QEN71_RS03665 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 153
Acidovorax sp. GW101-3H11 0.26 Ac3H11_3062 transcriptional regulator, TetR family 0.30 Ac3H11_3664 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)
Pseudomonas sp. S08-1 0.25 OH686_23880 Transcriptional regulator, AcrR family 0.32 OH686_13550 Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase / GTP pyrophosphokinase , (p)ppGpp synthetase II low > 80
Pseudomonas putida KT2440 0.23 PP_2880 Transcriptional regulator, TetR family 0.32 PP_5302 bifunctional (p)ppGpp synthase/hydrolase
Herbaspirillum seropedicae SmR1 0.21 HSERO_RS06360 transcription regulator protein 0.33 HSERO_RS10635 guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase
Bosea sp. OAE506 0.19 ABIE41_RS09935 TetR/AcrR family transcriptional regulator 0.45 ABIE41_RS19890 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 77
Ralstonia sp. UNC404CL21Col 0.18 ABZR87_RS23280 TetR/AcrR family transcriptional regulator 0.34 ABZR87_RS15225 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 80
Ralstonia solanacearum GMI1000 0.16 RS_RS06015 TetR/AcrR family transcriptional regulator 0.34 RS_RS10800 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase
Shewanella amazonensis SB2B 0.14 Sama_0476 TetR family transcriptional regulator (RefSeq) 0.35 Sama_0264 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (RefSeq) low > 62
Dechlorosoma suillum PS 0.13 Dsui_1876 transcriptional regulator 0.34 Dsui_0500 (p)ppGpp synthetase, RelA/SpoT family low > 51

Not shown: 0 genomes with orthologs for A4249_RS00170 only; 54 genomes with orthologs for A4249_RS05505 only