Conservation of cofitness between b1827 and b2025 in Escherichia coli BW25113

55 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b1827 kdgR predicted DNA-binding transcriptional regulator (NCBI) 1.0 b2025 hisF imidazole glycerol phosphate synthase subunit HisF (NCBI) 0.23 19
Escherichia coli ECRC101 1.00 MCAODC_18925 kdgR DNA-binding transcriptional regulator KdgR 1.00 MCAODC_20450 hisF Imidazole glycerol phosphate synthase subunit HisF
Escherichia coli ECRC99 1.00 KEDOAH_01625 kdgR DNA-binding transcriptional regulator KdgR 1.00 KEDOAH_03660 hisF Imidazole glycerol phosphate synthase subunit HisF
Escherichia coli ECRC98 1.00 JDDGAC_01055 kdgR DNA-binding transcriptional regulator KdgR 1.00 JDDGAC_28600 hisF Imidazole glycerol phosphate synthase subunit HisF
Escherichia coli BL21 1.00 ECD_01798 KDG regulon transcriptional repressor 0.99 ECD_01927 imidazole glycerol phosphate synthase, catalytic subunit with HisH
Escherichia coli ECRC101 1.00 OKFHMN_26480 kdgR DNA-binding transcriptional regulator KdgR 1.00 OKFHMN_24490 hisF Imidazole glycerol phosphate synthase subunit HisF
Escherichia coli ECRC102 1.00 NIAGMN_01580 kdgR DNA-binding transcriptional regulator KdgR 1.00 NIAGMN_22435 hisF Imidazole glycerol phosphate synthase subunit HisF
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_01904 Transcriptional regulator KdgR 0.99 OHPLBJKB_01675 Imidazole glycerol phosphate synthase subunit HisF low > 73
Escherichia coli ECOR38 0.99 HEPCGN_04880 kdgR DNA-binding transcriptional regulator KdgR 0.99 HEPCGN_03195 hisF Imidazole glycerol phosphate synthase subunit HisF low > 85
Escherichia coli Nissle 1917 0.99 ECOLIN_RS10175 DNA-binding transcriptional regulator KdgR 1.00 ECOLIN_RS11970 imidazole glycerol phosphate synthase subunit HisF
Escherichia fergusonii Becca 0.99 EFB2_02174 Transcriptional regulator KdgR 1.00 EFB2_01831 Imidazole glycerol phosphate synthase subunit HisF low > 86
Escherichia coli ECRC62 0.99 BNILDI_15785 kdgR DNA-binding transcriptional regulator KdgR 1.00 BNILDI_14715 hisF Imidazole glycerol phosphate synthase subunit HisF
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.96 GFF2842 Transcriptional regulator KdgR, KDG operon repressor 0.95 GFF3907 Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) low > 78
Enterobacter asburiae PDN3 0.95 EX28DRAFT_0729 transcriptional regulator, IclR family 0.96 EX28DRAFT_0534 imidazoleglycerol phosphate synthase, cyclase subunit low > 76
Enterobacter sp. TBS_079 0.95 MPMX20_02734 Transcriptional regulator KdgR 0.97 MPMX20_03007 Imidazole glycerol phosphate synthase subunit HisF low > 85
Klebsiella michiganensis M5al 0.95 BWI76_RS17960 DNA-binding transcriptional regulator KdgR 0.96 BWI76_RS18950 imidazole glycerol phosphate synthase cyclase subunit
Dickeya dadantii 3937 0.91 DDA3937_RS11445 DNA-binding transcriptional regulator KdgR 0.93 DDA3937_RS09710 imidazole glycerol phosphate synthase subunit HisF low > 74
Dickeya dianthicola ME23 0.90 DZA65_RS11830 DNA-binding transcriptional regulator KdgR 0.92 DZA65_RS10030 imidazole glycerol phosphate synthase subunit HisF low > 75
Dickeya dianthicola 67-19 0.90 HGI48_RS11490 DNA-binding transcriptional regulator KdgR 0.92 HGI48_RS09720 imidazole glycerol phosphate synthase subunit HisF
Pectobacterium carotovorum WPP14 0.89 HER17_RS11535 DNA-binding transcriptional regulator KdgR 0.91 HER17_RS12255 imidazole glycerol phosphate synthase subunit HisF low > 75
Pantoea sp. MT58 0.86 IAI47_08720 DNA-binding transcriptional regulator KdgR 0.90 IAI47_07065 imidazole glycerol phosphate synthase subunit HisF low > 76
Rahnella sp. WP5 0.85 EX31_RS24895 DNA-binding transcriptional regulator KdgR 0.91 EX31_RS11465 imidazole glycerol phosphate synthase subunit HisF low > 89
Serratia liquefaciens MT49 0.82 IAI46_10820 DNA-binding transcriptional regulator KdgR 0.95 IAI46_08185 imidazole glycerol phosphate synthase subunit HisF low > 86
Erwinia tracheiphila SCR3 0.80 LU632_RS13230 kdgR DNA-binding transcriptional regulator KdgR 0.93 LU632_RS08920 hisF imidazole glycerol phosphate synthase subunit HisF low > 74
Burkholderia phytofirmans PsJN 0.63 BPHYT_RS10950 transcriptional regulator 0.41 BPHYT_RS17680 imidazole glycerol phosphate synthase subunit HisF low > 109
Ralstonia sp. UNC404CL21Col 0.62 ABZR87_RS20805 DNA-binding transcriptional regulator KdgR 0.42 ABZR87_RS02470 imidazole glycerol phosphate synthase subunit HisF
Paraburkholderia bryophila 376MFSha3.1 0.62 H281DRAFT_01160 transcriptional regulator, IclR family 0.41 H281DRAFT_05659 imidazole glycerol phosphate synthase subunit hisF
Paraburkholderia graminis OAS925 0.62 ABIE53_002286 IclR family KDG regulon transcriptional repressor 0.41 ABIE53_003695 cyclase
Paraburkholderia sabiae LMG 24235 0.61 QEN71_RS37295 DNA-binding transcriptional regulator KdgR 0.40 QEN71_RS27835 imidazole glycerol phosphate synthase subunit HisF low > 153
Pseudomonas fluorescens FW300-N2C3 0.52 AO356_28560 transcriptional regulator 0.40 AO356_09795 imidazole glycerol phosphate synthase subunit HisF low > 104
Cupriavidus basilensis FW507-4G11 0.27 RR42_RS34920 IclR family transcriptional regulator 0.42 RR42_RS18885 imidazole glycerol phosphate synthase
Rhodopseudomonas palustris CGA009 0.26 TX73_024130 IclR family transcriptional regulator 0.33 TX73_001625 imidazole glycerol phosphate synthase subunit HisF
Agrobacterium fabrum C58 0.26 Atu0706 transcriptional regulator, IclR family 0.37 Atu0039 imidazoleglycerol-phosphate synthase cyclase low > 89
Pseudomonas fluorescens FW300-N1B4 0.26 Pf1N1B4_3230 Pca regulon regulatory protein PcaR 0.40 Pf1N1B4_1623 Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-)
Pseudomonas fluorescens SBW25 0.26 PFLU_RS06715 IclR family transcriptional regulator 0.40 PFLU_RS01625 imidazole glycerol phosphate synthase subunit HisF low > 109
Pseudomonas fluorescens FW300-N2E2 0.26 Pf6N2E2_2839 Pca regulon regulatory protein PcaR 0.40 Pf6N2E2_3838 Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-)
Pseudomonas fluorescens SBW25-INTG 0.26 PFLU_RS06715 IclR family transcriptional regulator 0.40 PFLU_RS01625 imidazole glycerol phosphate synthase subunit HisF low > 109
Variovorax sp. SCN45 0.25 GFF3166 Transcriptional regulator, IclR family 0.39 GFF5357 Imidazole glycerol phosphate synthase cyclase subunit
Pseudomonas fluorescens GW456-L13 0.25 PfGW456L13_4594 Pca regulon regulatory protein PcaR 0.40 PfGW456L13_358 Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) low > 87
Pseudomonas simiae WCS417 0.25 PS417_06690 IclR family transcriptional regulator 0.40 PS417_01580 imidazole glycerol phosphate synthase low > 88
Pseudomonas fluorescens FW300-N2E3 0.25 AO353_17185 IclR family transcriptional regulator 0.40 AO353_12090 imidazole glycerol phosphate synthase subunit HisF low > 101
Pseudomonas sp. RS175 0.25 PFR28_00618 Pca regulon regulatory protein 0.40 PFR28_04933 Imidazole glycerol phosphate synthase subunit HisF low > 88
Pseudomonas syringae pv. syringae B728a 0.24 Psyr_4014 regulatory protein, IclR 0.40 Psyr_4893 imidazole glycerol phosphate synthase subunit hisF 0.34 57
Pseudomonas syringae pv. syringae B728a ΔmexB 0.24 Psyr_4014 regulatory protein, IclR 0.40 Psyr_4893 imidazole glycerol phosphate synthase subunit hisF
Pseudomonas putida KT2440 0.24 PP_1375 transcription regulatory protein (pca regulon) 0.41 PP_0293 Imidazole glycerol phosphate synthase subunit HisF low > 96
Hydrogenophaga sp. GW460-11-11-14-LB1 0.22 GFF2386 Pca regulon regulatory protein PcaR 0.38 GFF1309 Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-)
Herbaspirillum seropedicae SmR1 0.22 HSERO_RS02910 IclR family transcriptional regulator 0.39 HSERO_RS20315 imidazole glycerol phosphate synthase low > 78
Parabacteroides merdae CL09T00C40 0.22 HMPREF1078_RS01425 IclR family transcriptional regulator 0.43 HMPREF1078_RS13565 imidazole glycerol phosphate synthase subunit HisF low > 61
Xanthomonas campestris pv. campestris strain 8004 0.22 Xcc-8004.484.1 Pca regulon regulatory protein PcaR 0.63 Xcc-8004.2943.1 Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) low > 74
Variovorax sp. OAS795 0.21 ABID97_RS24205 IclR family transcriptional regulator C-terminal domain-containing protein 0.41 ABID97_RS23105 imidazole glycerol phosphate synthase subunit HisF
Acidovorax sp. GW101-3H11 0.21 Ac3H11_3923 Transcriptional regulator, IclR family 0.34 Ac3H11_4733 Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-)
Phaeobacter inhibens DSM 17395 0.20 PGA1_c07430 putative transcriptional regulator, IclR family 0.34 PGA1_c09240 imidazole glycerol phosphate synthase subunit HisF
Acinetobacter radioresistens SK82 0.19 MPMX26_01897 hypothetical protein 0.40 MPMX26_02854 Imidazole glycerol phosphate synthase subunit HisF low > 36
Pseudomonas stutzeri RCH2 0.19 Psest_3073 beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family 0.42 Psest_0156 imidazoleglycerol phosphate synthase, cyclase subunit
Dyella japonica UNC79MFTsu3.2 0.14 ABZR86_RS01165 IclR family transcriptional regulator 0.63 ABZR86_RS06705 imidazole glycerol phosphate synthase subunit HisF low > 74
Sphingomonas koreensis DSMZ 15582 0.10 Ga0059261_1684 transcriptional regulator, IclR family 0.35 Ga0059261_1048 imidazoleglycerol phosphate synthase, cyclase subunit low > 68

Not shown: 0 genomes with orthologs for b1827 only; 46 genomes with orthologs for b2025 only