| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Variovorax sp. SCN45 | GFF7469 | | Beta-lactamase class C-like and penicillin binding proteins (PBPs) superfamily / DUF3471 domain | no data | 100 | 100 |
| | Lysobacter sp. OAE881 | ABIE51_RS11230 | | serine hydrolase | insig. | 77 | 100 |
| | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.1849.1 | | Beta-lactamase (EC 3.5.2.6) | insig. | 63 | 100 |
| | Rhodanobacter denitrificans MT42 | LRK55_RS01200 | | serine hydrolase | insig. | 60 | 100 |
| | Rhodanobacter denitrificans FW104-10B01 | LRK54_RS01435 | | serine hydrolase | insig. | 60 | 100 |
| | Rhodanobacter sp000427505 FW510-R12 | LRK53_RS08605 | | serine hydrolase | insig. | 60 | 100 |
| | Rhodanobacter sp. FW510-T8 | OKGIIK_05105 | ampC | serine hydrolase | insig. | 59 | 100 |
| | Dyella japonica UNC79MFTsu3.2 | ABZR86_RS00270 | | serine hydrolase | cofit | 57 | 100 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS23910 | | serine hydrolase | insig. | 45 | 91 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_1807 | | Beta-lactamase class C and other penicillin binding proteins | insig. | 41 | 100 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_00625 | | serine hydrolase | insig. | 38 | 96 |
| | Caulobacter crescentus NA1000 | CCNA_03183 | | beta-lactamase family protein | insig. | 37 | 96 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_03183 | | beta-lactamase family protein | cofit | 37 | 96 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_1344 | | Beta-lactamase class C and other penicillin binding proteins | insig. | 42 | 85 |
| | Lysobacter sp. OAE881 | ABIE51_RS15060 | | serine hydrolase | insig. | 35 | 98 |
| | Variovorax sp. SCN45 | GFF459 | | Beta-lactamase class C-like and penicillin binding proteins (PBPs) superfamily / DUF3471 domain | insig. | 33 | 96 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_4014 | | Beta-lactamase class C and other penicillin binding proteins | insig. | 32 | 96 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_18155 | | serine hydrolase | insig. | 28 | 100 |
| | Dyella japonica UNC79MFTsu3.2 | ABZR86_RS12150 | | serine hydrolase domain-containing protein | insig. | 39 | 82 |
| | Lysobacter sp. OAE881 | ABIE51_RS13660 | | serine hydrolase domain-containing protein | insig. | 42 | 82 |
| | Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS10325 | | serine hydrolase | insig. | 35 | 90 |
| | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.1573.1 | | Beta-lactamase (EC 3.5.2.6) | strong | 30 | 98 |
| | Shewanella loihica PV-4 | Shew_1968 | | beta-lactamase (RefSeq) | insig. | 32 | 83 |
| | Sphingobium sp. HT1-2 | GFF2759 | | Beta-lactamase class C-like and penicillin binding proteins (PBPs) superfamily | insig. | 37 | 83 |
| | Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS11025 | | serine hydrolase | insig. | 34 | 96 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_06670 | | hypothetical protein | insig. | 28 | 96 |
| | Dyella japonica UNC79MFTsu3.2 | ABZR86_RS14480 | | serine hydrolase domain-containing protein | insig. | 30 | 99 |
| | Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS05545 | | serine hydrolase domain-containing protein | cofit | 38 | 82 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS23115 | | serine hydrolase | insig. | 32 | 96 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_3669 | | Beta-lactamase class C and other penicillin binding proteins | insig. | 36 | 85 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_08675 | | hypothetical protein | sig. | 33 | 85 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_1175 | | Beta-lactamase class C and other penicillin binding proteins | insig. | 37 | 82 |
| | Caulobacter crescentus NA1000 | CCNA_01570 | | penicillin-binding protein | insig. | 31 | 87 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_01570 | | penicillin-binding protein | cofit | 31 | 87 |
| | Serratia liquefaciens MT49 | IAI46_02780 | | D-alanyl-D-alanine- carboxypeptidase/endopeptidase AmpH | insig. | 29 | 95 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS10765 | | serine hydrolase domain-containing protein | insig. | 35 | 83 |
| | Rhodanobacter sp000427505 FW510-R12 | LRK53_RS17060 | | beta-lactamase family protein | insig. | 38 | 82 |
| | Rahnella sp. WP5 | EX31_RS04370 | | D-alanyl-D-alanine- carboxypeptidase/endopeptidase AmpH | insig. | 30 | 83 |
| | Rhodanobacter sp. FW510-T8 | OKGIIK_01325 | | Serine hydrolase | cofit | 30 | 98 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_1650 | | Beta-lactamase class C and other penicillin binding proteins | insig. | 32 | 83 |
| | Rhodanobacter sp000427505 FW510-R12 | LRK53_RS04515 | | serine hydrolase | insig. | 30 | 98 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS20415 | | serine hydrolase | insig. | 31 | 98 |
| | Rhodanobacter denitrificans FW104-10B01 | LRK54_RS05485 | | serine hydrolase | strong | 30 | 98 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS12260 | | serine hydrolase | insig. | 29 | 92 |
| | Rhodanobacter denitrificans MT42 | LRK55_RS05260 | | serine hydrolase domain-containing protein | strong | 30 | 98 |
| | Dyella japonica UNC79MFTsu3.2 | ABZR86_RS12140 | | serine hydrolase domain-containing protein | insig. | 38 | 96 |
| | Rhodanobacter sp. FW510-T8 | OKGIIK_12395 | | Serine hydrolase | insig. | 38 | 82 |
| | Rhodanobacter denitrificans MT42 | LRK55_RS11195 | | serine hydrolase domain-containing protein | insig. | 37 | 82 |
| | Rhodanobacter denitrificans FW104-10B01 | LRK54_RS11465 | | serine hydrolase | insig. | 37 | 82 |
| | Pantoea sp. MT58 | IAI47_21050 | | beta-lactamase family protein | insig. | 28 | 83 |
| | Dyella japonica UNC79MFTsu3.2 | ABZR86_RS18895 | | serine hydrolase domain-containing protein | insig. | 29 | 98 |
| | Ralstonia solanacearum PSI07 | RPSI07_RS03050 | | penicillin-binding protein | insig. | 36 | 71 |
| | Rhodanobacter sp000427505 FW510-R12 | LRK53_RS17050 | | serine hydrolase | insig. | 35 | 96 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_1439 | | Beta-lactamase | insig. | 32 | 83 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_1439 | | Beta-lactamase | insig. | 32 | 83 |
| | Variovorax sp. SCN45 | GFF2397 | | Beta-lactamase class C-like and penicillin binding proteins (PBPs) superfamily | insig. | 35 | 81 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_2342 | | Beta-lactamase class C and other penicillin binding proteins | insig. | 31 | 98 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS25255 | | 1,4-butanediol diacrylate esterase | insig. | 35 | 95 |
| | Variovorax sp. OAS795 | ABID97_RS13020 | | serine hydrolase | insig. | 34 | 98 |
| | Rhodopseudomonas palustris CGA009 | TX73_008260 | | serine hydrolase | insig. | 32 | 99 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_09335 | | serine hydrolase | insig. | 31 | 83 |
| | Pantoea agglomerans CFBP13505 P0401 | PagCFBP13505_RS19890 | | D-alanyl-D-alanine- carboxypeptidase/endopeptidase AmpH | insig. | 27 | 83 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_3004 | | Beta-lactamase class C and other penicillin binding proteins | insig. | 29 | 84 |
| | Pantoea sp. MT58 | IAI47_05345 | | D-alanyl-D-alanine- carboxypeptidase/endopeptidase AmpH | insig. | 27 | 83 |
| | Rhodanobacter denitrificans FW104-10B01 | LRK54_RS11475 | | serine hydrolase | insig. | 32 | 96 |
| | Rhodanobacter sp. FW510-T8 | OKGIIK_12385 | | Penicillin-binding protein | insig. | 33 | 96 |
| | Erwinia amylovora T8 | OLJFJH_07570 | | D-alanyl-D-alanine-carboxypeptidase/endopeptidase AmpH | cofit | 26 | 83 |
| | Escherichia coli BL21 | ECD_00323 | | D-alanyl-D-alanine- carboxypeptidase/endopeptidase; penicillin-binding protein; weak beta-lactamase | insig. | 26 | 85 |
| | Escherichia coli ECOR27 | NOLOHH_01590 | ampH | D-alanyl-D-alanine-carboxypeptidase/endopeptidase AmpH | insig. | 26 | 85 |
| | Escherichia coli ECOR38 | HEPCGN_07305 | ampH | D-alanyl-D-alanine-carboxypeptidase/endopeptidase AmpH | insig. | 26 | 85 |
| | Escherichia coli ECRC100 | OKFHMN_08665 | ampH | D-alanyl-D-alanine-carboxypeptidase/endopeptidase AmpH | insig. | 26 | 85 |
| | Escherichia coli ECRC101 | MCAODC_27890 | ampH | D-alanyl-D-alanine-carboxypeptidase/endopeptidase AmpH | insig. | 26 | 85 |
| | Escherichia coli ECRC102 | NIAGMN_06720 | ampH | D-alanyl-D-alanine-carboxypeptidase/endopeptidase AmpH | cofit | 26 | 85 |
| | Escherichia coli ECRC62 | BNILDI_23000 | ampH | D-alanyl-D-alanine-carboxypeptidase/endopeptidase AmpH | insig. | 26 | 85 |
| | Escherichia coli ECRC98 | JDDGAC_12320 | ampH | D-alanyl-D-alanine-carboxypeptidase/endopeptidase AmpH | insig. | 26 | 85 |
| | Escherichia coli ECRC99 | KEDOAH_19305 | ampH | D-alanyl-D-alanine-carboxypeptidase/endopeptidase AmpH | no data | 26 | 85 |
| | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_03299 | | D-alanyl-D-alanine- carboxypeptidase/endopeptidase AmpH | insig. | 26 | 85 |
| | Escherichia coli BW25113 | b0376 | ampH | beta-lactamase/D-alanine carboxypeptidase (NCBI) | sig. | 26 | 85 |
| | Escherichia fergusonii Becca | EFB2_03681 | | D-alanyl-D-alanine- carboxypeptidase/endopeptidase AmpH | insig. | 26 | 85 |
| | Escherichia coli Nissle 1917 | ECOLIN_RS02290 | | D-alanyl-D-alanine- carboxypeptidase/endopeptidase AmpH | insig. | 26 | 85 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_4162 | | Beta-lactamase class C and other penicillin binding proteins | insig. | 29 | 94 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_2941 | | Beta-lactamase class C and other penicillin binding proteins | insig. | 31 | 83 |
| | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF4271 | | Penicillin-binding protein AmpH | insig. | 25 | 85 |
| | Dyella japonica UNC79MFTsu3.2 | ABZR86_RS18325 | | serine hydrolase domain-containing protein | insig. | 33 | 82 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_3998 | | Beta-lactamase class C and other penicillin binding proteins | insig. | 34 | 83 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_1698 | | Beta-lactamase class C and other penicillin binding proteins | insig. | 32 | 82 |
| | Caulobacter crescentus NA1000 | CCNA_01778 | | penicillin-binding protein | cofit | 28 | 84 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_01778 | | penicillin-binding protein | cofit | 28 | 84 |
| | Caulobacter crescentus NA1000 | CCNA_00912 | | beta-lactamase family protein | sig. | 46 | 41 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_00912 | | beta-lactamase family protein | cofit | 46 | 41 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS19605 | | serine hydrolase | strong | 31 | 80 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS04540 | | serine hydrolase | insig. | 33 | 84 |
| | Xanthobacter sp. DMC5 | GFF2947 | | D-aminopeptidase | insig. | 34 | 98 |
| | Ralstonia solanacearum IBSBF1503 | RALBFv3_RS22355 | | penicillin-binding protein | insig. | 33 | 64 |
| | Ralstonia solanacearum UW163 | UW163_RS22900 | | penicillin-binding protein | insig. | 33 | 64 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_0658 | | Beta-lactamase class C and other penicillin binding proteins | insig. | 31 | 98 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS34325 | | beta-lactamase | insig. | 32 | 91 |
| | Enterobacter asburiae PDN3 | EX28DRAFT_2598 | | Beta-lactamase class C and other penicillin binding proteins | insig. | 23 | 85 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_07830 | | hypothetical protein | cofit | 31 | 83 |
| | Klebsiella michiganensis M5al | BWI76_RS06095 | | D-alanyl-D-alanine- carboxypeptidase/endopeptidase AmpH | insig. | 26 | 85 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS12410 | | serine hydrolase | insig. | 29 | 97 |
| | Rhodopseudomonas palustris CGA009 | TX73_014545 | | serine hydrolase | insig. | 31 | 99 |
| | Variovorax sp. SCN45 | GFF1777 | | Beta-lactamase class C-like and penicillin binding proteins (PBPs) superfamily | insig. | 30 | 82 |
| | Enterobacter sp. TBS_079 | MPMX20_00963 | | D-alanyl-D-alanine- carboxypeptidase/endopeptidase AmpH | insig. | 23 | 85 |
| | Caulobacter crescentus NA1000 | CCNA_01638 | | beta-lactamase family protein | strong | 31 | 71 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_01638 | | beta-lactamase family protein | cofit | 31 | 71 |
| | Enterobacter asburiae PDN3 | EX28DRAFT_3350 | | Beta-lactamase class C and other penicillin binding proteins | insig. | 31 | 83 |
| | Pseudomonas simiae WCS417 | PS417_14945 | | beta-lactamase | strong | 28 | 97 |
| | Mycobacterium tuberculosis H37Rv | Rv0907 | | Conserved protein | insig. | 34 | 98 |
| | Cellulophaga baltica 18 | M666_RS16400 | | serine hydrolase | insig. | 32 | 90 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_1705 | | Beta-lactamase class C and other penicillin binding proteins | insig. | 31 | 82 |
| | Mycobacterium tuberculosis H37Rv | Rv1730c | | Possible penicillin-binding protein | insig. | 29 | 82 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS27845 | | beta-lactamase | insig. | 29 | 83 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_1260 | | Beta-lactamase class C family protein | insig. | 27 | 84 |
| | Klebsiella pneumoniae MKP103 | KDGMDA_14190 | | D-alanyl-D-alanine-carboxypeptidase/endopeptidase AmpH | insig. | 24 | 85 |
| | Klebsiella pneumoniae MRSN742743 | KFA93_RS04095 | ampH;inference=COORDINATES | D-alanyl-D-alanine-carboxypeptidase/endopeptidase AmpH | insig. | 24 | 85 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS20210 | | serine hydrolase | sig. | 34 | 79 |
| | Sphingobium sp. HT1-2 | GFF2038 | | Beta-lactamase class C-like and penicillin binding proteins (PBPs) superfamily | insig. | 32 | 96 |
| | Rhodanobacter denitrificans MT42 | LRK55_RS11205 | | serine hydrolase | insig. | 31 | 71 |
| | Ralstonia sp. UNC404CL21Col | ABZR87_RS22500 | | serine hydrolase domain-containing protein | insig. | 30 | 98 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_0778 | | Beta-glucosidase-related glycosidases | strong | 26 | 85 |
| | Erwinia tracheiphila HP pepo 2.2 | IJEDHG_13340 | ampH | D-alanyl-D-alanine-carboxypeptidase/endopeptidase AmpH | cofit | 25 | 85 |
| | Erwinia tracheiphila SCR3 | LU632_RS21660 | ampH | D-alanyl-D-alanine- carboxypeptidase/endopeptidase AmpH | insig. | 25 | 85 |
| | Azospirillum sp. SherDot2 | MPMX19_02152 | | hypothetical protein | insig. | 34 | 63 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS17145 | | serine hydrolase domain-containing protein | insig. | 29 | 97 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS18895 | | hypothetical protein | insig. | 30 | 85 |
| | Sphingobium sp. HT1-2 | GFF3809 | | Beta-lactamase class C-like and penicillin binding proteins (PBPs) superfamily | cofit | 25 | 92 |
| | Caulobacter crescentus NA1000 | CCNA_03603 | | beta-lactamase family protein | insig. | 30 | 83 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_03603 | | beta-lactamase family protein | cofit | 30 | 83 |