Conservation of cofitness between PP_4922 and PP_1063 in Pseudomonas putida KT2440

52 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pseudomonas putida KT2440 1.0 PP_4922 Phosphomethylpyrimidine synthase 1.0 PP_1063 DNA-binding transcriptional regulator, homocysteine-binding 0.50 17
Pseudomonas sp. RS175 0.92 PFR28_05091 Phosphomethylpyrimidine synthase 0.96 PFR28_03478 HTH-type transcriptional regulator MetR low > 88
Pseudomonas fluorescens FW300-N2C3 0.92 AO356_08810 thiamine biosynthesis protein ThiC 0.95 AO356_17735 XRE family transcriptional regulator low > 104
Pseudomonas fluorescens FW300-N2E2 0.92 Pf6N2E2_3644 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.95 Pf6N2E2_5471 Transcriptional activator MetR low > 103
Pseudomonas syringae pv. syringae B728a 0.92 Psyr_0544 hydroxymethylpyrimidine synthase 0.94 Psyr_3917 transcriptional regulator, LysR family low > 86
Pseudomonas fluorescens GW456-L13 0.92 PfGW456L13_187 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.95 PfGW456L13_4778 Transcriptional activator MetR low > 87
Pseudomonas fluorescens SBW25-INTG 0.92 PFLU_RS02430 phosphomethylpyrimidine synthase ThiC 0.95 PFLU_RS05540 LysR family transcriptional regulator low > 109
Pseudomonas syringae pv. syringae B728a ΔmexB 0.92 Psyr_0544 hydroxymethylpyrimidine synthase 0.94 Psyr_3917 transcriptional regulator, LysR family 0.45 37
Pseudomonas fluorescens SBW25 0.92 PFLU_RS02430 phosphomethylpyrimidine synthase ThiC 0.95 PFLU_RS05540 LysR family transcriptional regulator low > 109
Pseudomonas fluorescens FW300-N2E3 0.92 AO353_13010 thiamine biosynthesis protein ThiC 0.95 AO353_16210 XRE family transcriptional regulator low > 101
Pseudomonas simiae WCS417 0.91 PS417_02355 thiamine biosynthesis protein ThiC 0.94 PS417_05455 XRE family transcriptional regulator low > 88
Pseudomonas fluorescens FW300-N1B4 0.91 Pf1N1B4_1447 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.95 Pf1N1B4_784 Transcriptional activator MetR low > 87
Pseudomonas sp. S08-1 0.91 OH686_15885 phosphomethylpyrimidine synthase 0.90 OH686_20465 Transcriptional activator MetR low > 80
Pseudomonas stutzeri RCH2 0.90 Psest_0477 thiamine biosynthesis protein ThiC 0.90 Psest_1450 Transcriptional regulator — —
Acinetobacter radioresistens SK82 0.77 MPMX26_00180 Phosphomethylpyrimidine synthase 0.47 MPMX26_01201 HTH-type transcriptional regulator MetR low > 36
Burkholderia phytofirmans PsJN 0.77 BPHYT_RS13220 phosphomethylpyrimidine synthase 0.46 BPHYT_RS26650 LysR family transcriptional regulator — —
Mucilaginibacter yixingensis YX-36 DSM 26809 0.75 ABZR88_RS08840 phosphomethylpyrimidine synthase ThiC 0.23 ABZR88_RS03450 LysR family transcriptional regulator low > 71
Castellaniella sp019104865 MT123 0.75 ABCV34_RS10825 phosphomethylpyrimidine synthase ThiC 0.56 ABCV34_RS04450 LysR substrate-binding domain-containing protein low > 48
Ralstonia solanacearum PSI07 0.74 RPSI07_RS23420 phosphomethylpyrimidine synthase ThiC 0.47 RPSI07_RS02550 LysR family transcriptional regulator low > 81
Ralstonia solanacearum UW163 0.74 UW163_RS03640 phosphomethylpyrimidine synthase ThiC 0.47 UW163_RS18860 LysR family transcriptional regulator — —
Ralstonia solanacearum IBSBF1503 0.74 RALBFv3_RS09940 phosphomethylpyrimidine synthase ThiC 0.47 RALBFv3_RS20315 LysR family transcriptional regulator 0.47 36
Ralstonia solanacearum GMI1000 0.74 RS_RS00555 phosphomethylpyrimidine synthase 0.46 RS_RS20365 LysR family transcriptional regulator low > 80
Shewanella loihica PV-4 0.74 Shew_2096 thiamine biosynthesis protein ThiC (RefSeq) 0.40 Shew_2987 LysR family transcriptional regulator (RefSeq) low > 60
Pantoea sp. MT58 0.73 IAI47_18085 phosphomethylpyrimidine synthase ThiC 0.43 IAI47_18315 HTH-type transcriptional regulator MetR low > 76
Cupriavidus basilensis FW507-4G11 0.73 RR42_RS01290 thiamine biosynthesis protein ThiC 0.46 RR42_RS30655 LysR family transcriptional regulator 0.78 15
Rahnella sp. WP5 0.73 EX31_RS16815 phosphomethylpyrimidine synthase ThiC 0.43 EX31_RS25370 HTH-type transcriptional regulator MetR low > 89
Serratia liquefaciens MT49 0.73 IAI46_01320 phosphomethylpyrimidine synthase ThiC 0.44 IAI46_01030 HTH-type transcriptional regulator MetR low > 86
Escherichia coli ECRC62 0.72 BNILDI_06005 thiC phosphomethylpyrimidine synthase ThiC 0.45 BNILDI_05070 metR HTH-type transcriptional regulator MetR — —
Escherichia fergusonii Becca 0.72 EFB2_04617 Phosphomethylpyrimidine synthase 0.45 EFB2_04809 HTH-type transcriptional regulator MetR low > 86
Escherichia coli ECOR27 0.72 NOLOHH_05520 thiC phosphomethylpyrimidine synthase ThiC 0.45 NOLOHH_06460 metR HTH-type transcriptional regulator MetR low > 57
Escherichia coli HS(pFamp)R (ATCC 700891) 0.72 OHPLBJKB_04056 Phosphomethylpyrimidine synthase 0.45 OHPLBJKB_04223 HTH-type transcriptional regulator MetR low > 73
Escherichia coli Nissle 1917 0.72 ECOLIN_RS23040 phosphomethylpyrimidine synthase ThiC 0.45 ECOLIN_RS30005 HTH-type transcriptional regulator MetR — —
Escherichia coli BW25113 0.72 b3994 thiC thiamine biosynthesis protein ThiC (NCBI) 0.45 b3828 metR DNA-binding transcriptional activator, homocysteine-binding (NCBI) 0.73 8
Escherichia coli ECRC98 0.72 JDDGAC_17000 thiC phosphomethylpyrimidine synthase ThiC 0.45 JDDGAC_17955 metR HTH-type transcriptional regulator MetR — —
Shewanella amazonensis SB2B 0.72 Sama_1860 thiamine biosynthesis protein ThiC (RefSeq) 0.40 Sama_2628 transcriptional activator protein MetR (RefSeq) low > 62
Escherichia coli ECRC102 0.72 NIAGMN_11125 thiC phosphomethylpyrimidine synthase ThiC 0.45 NIAGMN_12085 metR HTH-type transcriptional regulator MetR — —
Escherichia coli ECRC101 0.72 OKFHMN_13375 thiC phosphomethylpyrimidine synthase ThiC 0.45 OKFHMN_14330 metR HTH-type transcriptional regulator MetR — —
Escherichia coli ECRC99 0.72 KEDOAH_14785 thiC phosphomethylpyrimidine synthase ThiC 0.45 KEDOAH_13820 metR HTH-type transcriptional regulator MetR — —
Escherichia coli ECRC101 0.72 MCAODC_03875 thiC phosphomethylpyrimidine synthase ThiC 0.45 MCAODC_04835 metR HTH-type transcriptional regulator MetR — —
Enterobacter sp. TBS_079 0.72 MPMX20_00217 Phosphomethylpyrimidine synthase 0.46 MPMX20_04452 HTH-type transcriptional regulator MetR low > 85
Dickeya dianthicola ME23 0.72 DZA65_RS01215 phosphomethylpyrimidine synthase ThiC 0.43 DZA65_RS00870 HTH-type transcriptional regulator MetR 0.81 17
Escherichia coli ECOR38 0.72 HEPCGN_12010 thiC phosphomethylpyrimidine synthase ThiC 0.45 HEPCGN_13030 metR HTH-type transcriptional regulator MetR low > 85
Escherichia coli BL21 0.72 ECD_03871 phosphomethylpyrimidine synthase 0.45 ECD_03707 methionine biosynthesis regulon transcriptional regulator low > 60
Enterobacter asburiae PDN3 0.72 EX28DRAFT_4536 phosphomethylpyrimidine synthase 0.45 EX28DRAFT_4493 Transcriptional regulator low > 76
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.72 GFF4198 Thiamin biosynthesis protein ThiC 0.44 GFF253 Transcriptional activator MetR low > 78
Klebsiella michiganensis M5al 0.71 BWI76_RS01555 phosphomethylpyrimidine synthase ThiC 0.42 BWI76_RS01275 LysR family transcriptional regulator 0.68 4
Shewanella oneidensis MR-1 0.71 SO2445 thiC thiamin biosynthesis protein ThiC (NCBI ptt file) 0.41 SO0817 metR transcriptional activator protein MetR (NCBI ptt file) low > 76
Vibrio cholerae E7946 ATCC 55056 0.71 CSW01_00335 phosphomethylpyrimidine synthase 0.51 CSW01_08580 HTH-type transcriptional regulator MetR low > 62
Shewanella sp. ANA-3 0.70 Shewana3_1936 thiamine biosynthesis protein ThiC (RefSeq) 0.41 Shewana3_3470 LysR family transcriptional regulator (RefSeq) low > 73
Variovorax sp. OAS795 0.68 ABID97_RS25235 phosphomethylpyrimidine synthase ThiC 0.47 ABID97_RS19400 LysR family transcriptional regulator — —
Acidovorax sp. GW101-3H11 0.67 Ac3H11_2027 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.51 Ac3H11_2344 Transcriptional activator MetR 0.92 13
Dinoroseobacter shibae DFL-12 0.65 Dshi_4080 thiamine biosynthesis protein ThiC (RefSeq) 0.46 Dshi_2079 transcriptional regulator, LysR family (RefSeq) — —
Azospirillum sp. SherDot2 0.64 MPMX19_00336 Phosphomethylpyrimidine synthase 0.37 MPMX19_00645 HTH-type transcriptional regulator MetR low > 112

Not shown: 41 genomes with orthologs for PP_4922 only; 0 genomes with orthologs for PP_1063 only