Conservation of cofitness between EX31_RS21480 and EX31_RS03485 in Rahnella sp. WP5

54 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Rahnella sp. WP5 1.0 EX31_RS21480 5-formyltetrahydrofolate cyclo-ligase 1.0 EX31_RS03485 pyruvate dehydrogenase complex transcriptional repressor PdhR 0.47 20
Pectobacterium carotovorum WPP14 0.69 HER17_RS19095 5-formyltetrahydrofolate cyclo-ligase 0.85 HER17_RS03285 pyruvate dehydrogenase complex transcriptional repressor PdhR low > 75
Serratia liquefaciens MT49 0.65 IAI46_20895 5-formyltetrahydrofolate cyclo-ligase 0.92 IAI46_21330 pyruvate dehydrogenase complex transcriptional repressor PdhR low > 86
Dickeya dadantii 3937 0.63 DDA3937_RS02410 5-formyltetrahydrofolate cyclo-ligase 0.84 DDA3937_RS17930 pyruvate dehydrogenase complex transcriptional repressor PdhR low > 74
Escherichia coli ECOR38 0.62 HEPCGN_18775 ygfA 5-formyltetrahydrofolate cyclo-ligase 0.78 HEPCGN_08490 pdhR pyruvate dehydrogenase complex transcriptional repressor PdhR low > 87
Escherichia coli Nissle 1917 0.62 ECOLIN_RS16205 5-formyltetrahydrofolate cyclo-ligase 0.78 ECOLIN_RS00635 pyruvate dehydrogenase complex transcriptional repressor PdhR low > 55
Dickeya dianthicola 67-19 0.62 HGI48_RS02370 5-formyltetrahydrofolate cyclo-ligase 0.84 HGI48_RS17855 pyruvate dehydrogenase complex transcriptional repressor PdhR low > 71
Escherichia coli ECRC100 0.62 OKFHMN_19485 ygfA 5-formyltetrahydrofolate cyclo-ligase 0.78 OKFHMN_10510 pdhR pyruvate dehydrogenase complex transcriptional repressor PdhR low > 80
Escherichia coli ECRC62 0.62 BNILDI_09930 ygfA 5-formyltetrahydrofolate cyclo-ligase 0.78 BNILDI_08755 pdhR pyruvate dehydrogenase complex transcriptional repressor PdhR low > 75
Escherichia coli ECRC101 0.62 MCAODC_10005 ygfA 5-formyltetrahydrofolate cyclo-ligase 0.78 MCAODC_01025 pdhR pyruvate dehydrogenase complex transcriptional repressor PdhR low > 87
Escherichia fergusonii Becca 0.62 EFB2_00991 5-formyltetrahydrofolate cyclo-ligase 0.78 EFB2_03932 Pyruvate dehydrogenase complex repressor low > 86
Escherichia coli ECRC99 0.62 KEDOAH_08655 ygfA 5-formyltetrahydrofolate cyclo-ligase 0.78 KEDOAH_17645 pdhR pyruvate dehydrogenase complex transcriptional repressor PdhR — —
Escherichia coli ECRC98 0.62 JDDGAC_23125 ygfA 5-formyltetrahydrofolate cyclo-ligase 0.78 JDDGAC_14105 pdhR pyruvate dehydrogenase complex transcriptional repressor PdhR low > 86
Escherichia coli ECOR27 0.62 NOLOHH_11395 ygfA 5-formyltetrahydrofolate cyclo-ligase 0.78 NOLOHH_02855 pdhR pyruvate dehydrogenase complex transcriptional repressor PdhR 0.73 27
Escherichia coli ECRC102 0.62 NIAGMN_17250 ygfA 5-formyltetrahydrofolate cyclo-ligase 0.78 NIAGMN_08360 pdhR pyruvate dehydrogenase complex transcriptional repressor PdhR — —
Enterobacter sp. TBS_079 0.60 MPMX20_03770 5-formyltetrahydrofolate cyclo-ligase 0.80 MPMX20_00806 Pyruvate dehydrogenase complex repressor low > 85
Klebsiella michiganensis M5al 0.60 BWI76_RS23915 5-formyltetrahydrofolate cyclo-ligase 0.79 BWI76_RS04875 transcriptional regulator PdhR low > 92
Escherichia coli BL21 0.60 ECD_02743 5-formyltetrahydrofolate cyclo-ligase family protein 0.78 ECD_00112 pyruvate dehydrogenase complex repressor; autorepressor low > 61
Escherichia coli HS(pFamp)R (ATCC 700891) 0.60 OHPLBJKB_00804 5-formyltetrahydrofolate cyclo-ligase 0.78 OHPLBJKB_03548 Pyruvate dehydrogenase complex repressor low > 73
Escherichia coli BW25113 0.60 b2912 ygfA putative ligase (VIMSS) 0.78 b0113 pdhR transcriptional regulator of pyruvate dehydrogenase complex (NCBI) low > 76
Dickeya dianthicola ME23 0.59 DZA65_RS02475 5-formyltetrahydrofolate cyclo-ligase 0.83 DZA65_RS19005 pyruvate dehydrogenase complex transcriptional repressor PdhR low > 75
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.58 GFF3012 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) 0.78 GFF123 Transcriptional repressor for pyruvate dehydrogenase complex low > 78
Pantoea sp. MT58 0.56 IAI47_03730 5-formyltetrahydrofolate cyclo-ligase 0.82 IAI47_15815 pyruvate dehydrogenase complex transcriptional repressor PdhR low > 76
Enterobacter asburiae PDN3 0.55 EX28DRAFT_2964 5,10-methenyltetrahydrofolate synthetase 0.80 EX28DRAFT_3708 Transcriptional regulators low > 76
Erwinia tracheiphila SCR3 0.53 LU632_RS05860 5-formyltetrahydrofolate cyclo-ligase 0.80 LU632_RS03075 pdhR pyruvate dehydrogenase complex transcriptional repressor PdhR — —
Shewanella loihica PV-4 0.52 Shew_3069 5-formyltetrahydrofolate cyclo-ligase (RefSeq) 0.57 Shew_3432 pdhR transcriptional regulator PdhR (RefSeq) low > 60
Shewanella oneidensis MR-1 0.51 SO0774 5-formyltetrahydrofolate cyclo-ligase family protein (NCBI ptt file) 0.57 SO0423 pdhR pyruvate dehydrogenase complex repressor (NCBI ptt file) low > 76
Vibrio cholerae E7946 ATCC 55056 0.51 CSW01_12545 5-formyltetrahydrofolate cyclo-ligase 0.66 CSW01_12225 pyruvate dehydrogenase complex transcriptional repressor PdhR low > 62
Shewanella sp. ANA-3 0.50 Shewana3_3506 5-formyltetrahydrofolate cyclo-ligase (RefSeq) 0.57 Shewana3_0425 pdhR transcriptional regulator PdhR (RefSeq) low > 73
Shewanella amazonensis SB2B 0.41 Sama_2726 5-formyltetrahydrofolate cyclo-ligase family protein (RefSeq) 0.56 Sama_0374 pdhR transcriptional regulator PdhR (RefSeq) low > 62
Pseudomonas stutzeri RCH2 0.31 Psest_0170 5,10-methenyltetrahydrofolate synthetase 0.40 Psest_0956 Transcriptional regulators low > 67
Marinobacter adhaerens HP15 0.28 HP15_3211 5-formyltetrahydrofolate cyclo-ligase 0.39 HP15_4087 transcriptional regulator, GntR family low > 73
Pseudomonas simiae WCS417 0.28 PS417_27305 5-formyltetrahydrofolate cyclo-ligase 0.36 PS417_24100 transcriptional regulator PdhR low > 88
Pseudomonas fluorescens SBW25 0.27 PFLU_RS28965 5-formyltetrahydrofolate cyclo-ligase 0.39 PFLU_RS25940 FCD domain-containing protein low > 109
Pseudomonas fluorescens SBW25-INTG 0.27 PFLU_RS28965 5-formyltetrahydrofolate cyclo-ligase 0.39 PFLU_RS25940 FCD domain-containing protein low > 109
Pseudomonas fluorescens FW300-N2E3 0.26 AO353_08780 5-formyltetrahydrofolate cyclo-ligase 0.39 AO353_05695 transcriptional regulator PdhR low > 101
Pseudomonas fluorescens GW456-L13 0.26 PfGW456L13_892 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) 0.39 PfGW456L13_5113 Lactate-responsive regulator LldR in Enterobacteria, GntR family low > 87
Pseudomonas fluorescens FW300-N1B4 0.25 Pf1N1B4_2225 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) 0.39 Pf1N1B4_1185 Lactate-responsive regulator LldR in Enterobacteria, GntR family low > 87
Pseudomonas putida KT2440 0.25 PP_5203 5-formyltetrahydrofolate cyclo-ligase 0.37 PP_4734 DNA-binding transcriptional dual regulator, LldR-L-lactate low > 96
Pseudomonas sp. RS175 0.25 PFR28_04325 5-formyltetrahydrofolate cyclo-ligase 0.39 PFR28_00064 Pyruvate dehydrogenase complex repressor low > 88
Pseudomonas fluorescens FW300-N2E2 0.24 Pf6N2E2_4476 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) 0.38 Pf6N2E2_3379 Lactate-responsive regulator LldR in Enterobacteria, GntR family low > 103
Pseudomonas fluorescens FW300-N2C3 0.24 AO356_12990 5-formyltetrahydrofolate cyclo-ligase 0.38 AO356_07545 transcriptional regulator PdhR low > 104
Sinorhizobium meliloti 1021 0.24 SMc03974 hypothetical protein 0.30 SMc00829 transcriptional regulator low > 103
Acinetobacter radioresistens SK82 0.24 MPMX26_02298 5-formyltetrahydrofolate cyclo-ligase 0.24 MPMX26_02258 Putative L-lactate dehydrogenase operon regulatory protein low > 36
Pseudomonas sp. S08-1 0.24 OH686_11225 5-formyltetrahydrofolate cyclo-ligase 0.38 OH686_17020 Lactate-responsive regulator LldR in Enterobacteria, GntR family low > 80
Agrobacterium fabrum C58 0.22 Atu3731 5-formyltetrahydrofolate cyclo-ligase 0.28 Atu0662 transcriptional regulator, GntR family low > 89
Rhodospirillum rubrum S1H 0.22 Rru_A1084 5-formyltetrahydrofolate cyclo-ligase (NCBI) 0.23 Rru_A1414 regulatory protein GntR (NCBI) low > 58
Azospirillum brasilense Sp245 0.18 AZOBR_RS09025 5-formyltetrahydrofolate cyclo-ligase 0.23 AZOBR_RS25130 GntR family transcriptional regulator low > 97
Magnetospirillum magneticum AMB-1 0.17 AMB_RS16280 5-formyltetrahydrofolate cyclo-ligase 0.38 AMB_RS01210 FCD domain-containing protein — —
Castellaniella sp019104865 MT123 0.15 ABCV34_RS13555 5-formyltetrahydrofolate cyclo-ligase 0.30 ABCV34_RS10290 transcriptional regulator LldR — —
Dinoroseobacter shibae DFL-12 0.15 Dshi_2769 5-formyltetrahydrofolate cyclo-ligase (RefSeq) 0.32 Dshi_3026 GntR domain protein (RefSeq) low > 64
Paraburkholderia sabiae LMG 24235 0.15 QEN71_RS28640 5-formyltetrahydrofolate cyclo-ligase 0.29 QEN71_RS10135 FadR/GntR family transcriptional regulator low > 153
Phaeobacter inhibens DSM 17395 0.13 PGA1_c21820 5-formyltetrahydrofolate cycloligase-like protein 0.31 PGA1_c00760 putative pyruvate dehydrogenase complex repressor low > 62
Cupriavidus basilensis FW507-4G11 0.13 RR42_RS01400 5-formyltetrahydrofolate cyclo-ligase 0.25 RR42_RS21300 GntR family transcriptional regulator low > 128
Azospirillum sp. SherDot2 0.12 MPMX19_00693 5-formyltetrahydrofolate cyclo-ligase 0.28 MPMX19_06090 Pyruvate dehydrogenase complex repressor low > 112

Not shown: 24 genomes with orthologs for EX31_RS21480 only; 4 genomes with orthologs for EX31_RS03485 only