Conservation of cofitness between ECD_03708 and ECD_03038 in Escherichia coli BL21

53 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BL21 1.0 ECD_03708 5-methyltetrahydropteroyltriglutamate- homocysteine S-methyltransferase 1.0 ECD_03038 argininosuccinate synthetase 0.88 33
Escherichia coli Nissle 1917 1.00 ECOLIN_RS21980 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 1.00 ECOLIN_RS18275 argininosuccinate synthase 0.96 12
Escherichia coli BW25113 1.00 b3829 metE 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (NCBI) 1.00 b3172 argG argininosuccinate synthase (NCBI) 0.68 18
Escherichia fergusonii Becca 1.00 EFB2_04808 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 1.00 EFB2_00651 Argininosuccinate synthase low > 86
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_04222 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 1.00 OHPLBJKB_00528 Argininosuccinate synthase low > 73
Escherichia coli ECOR27 0.99 NOLOHH_06455 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 0.99 NOLOHH_09890 argG argininosuccinate synthase low > 75
Escherichia coli ECRC62 0.99 BNILDI_05075 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 0.99 BNILDI_01645 argG argininosuccinate synthase 0.97 36
Escherichia coli ECOR38 0.99 HEPCGN_13025 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 1.00 HEPCGN_16965 argG argininosuccinate synthase 0.98 7
Escherichia coli ECRC100 0.99 OKFHMN_14325 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 0.99 OKFHMN_18090 argG argininosuccinate synthase 0.96 41
Escherichia coli ECRC101 0.99 MCAODC_04830 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 0.99 MCAODC_08610 argG argininosuccinate synthase 0.92 26
Escherichia coli ECRC98 0.99 JDDGAC_17950 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 0.99 JDDGAC_21715 argG argininosuccinate synthase low > 86
Escherichia coli ECRC99 0.99 KEDOAH_13825 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 0.99 KEDOAH_10060 argG argininosuccinate synthase — —
Escherichia coli ECRC102 0.99 NIAGMN_12080 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 0.99 NIAGMN_15850 argG argininosuccinate synthase — —
Enterobacter asburiae PDN3 0.95 EX28DRAFT_4494 methionine synthase (B12-independent) (EC 2.1.1.14) 0.94 EX28DRAFT_3224 argininosuccinate synthase (EC 6.3.4.5) 0.73 28
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.94 GFF254 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (EC 2.1.1.14) 0.97 GFF2913 Argininosuccinate synthase (EC 6.3.4.5) 0.44 33
Klebsiella michiganensis M5al 0.94 BWI76_RS01280 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.95 BWI76_RS25115 argininosuccinate synthase 0.27 57
Enterobacter sp. TBS_079 0.94 MPMX20_04451 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.94 MPMX20_04077 Argininosuccinate synthase low > 85
Pectobacterium carotovorum WPP14 0.86 HER17_RS20685 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.92 HER17_RS21055 argininosuccinate synthase low > 75
Dickeya dadantii 3937 0.85 DDA3937_RS20380 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.92 DDA3937_RS20890 argininosuccinate synthase 0.53 28
Dickeya dianthicola ME23 0.85 DZA65_RS00875 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.92 DZA65_RS00355 argininosuccinate synthase low > 75
Dickeya dianthicola 67-19 0.85 HGI48_RS00820 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.92 HGI48_RS00355 argininosuccinate synthase low > 71
Erwinia tracheiphila SCR3 0.84 LU632_RS24030 metE 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.16 LU632_RS19605 argininosuccinate synthase low > 74
Serratia liquefaciens MT49 0.84 IAI46_01035 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.15 IAI46_24505 argininosuccinate synthase 0.87 1
Rahnella sp. WP5 0.83 EX31_RS14710 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.90 EX31_RS13445 argininosuccinate synthase low > 89
Pseudomonas sp. RS175 0.61 PFR28_03477 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.11 PFR28_03353 Argininosuccinate synthase — —
Pseudomonas stutzeri RCH2 0.60 Psest_1452 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 0.11 Psest_3121 argininosuccinate synthase — —
Pseudomonas fluorescens GW456-L13 0.59 PfGW456L13_3767 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (EC 2.1.1.14) 0.11 PfGW456L13_1749 Argininosuccinate synthase (EC 6.3.4.5) low > 87
Pseudomonas fluorescens SBW25 0.59 PFLU_RS17405 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.11 PFLU_RS05725 argininosuccinate synthase — —
Pseudomonas fluorescens SBW25-INTG 0.59 PFLU_RS17405 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.11 PFLU_RS05725 argininosuccinate synthase — —
Castellaniella sp019104865 MT123 0.59 ABCV34_RS04445 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.78 ABCV34_RS05390 argininosuccinate synthase — —
Pseudomonas sp. S08-1 0.59 OH686_20470 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.12 OH686_03930 argininosuccinate synthase low > 80
Paraburkholderia sabiae LMG 24235 0.57 QEN71_RS19725 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.80 QEN71_RS09235 argininosuccinate synthase 0.59 33
Azospirillum brasilense Sp245 0.56 AZOBR_RS24275 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 0.14 AZOBR_RS00785 argininosuccinate synthase — —
Ralstonia sp. UNC404CL21Col 0.56 ABZR87_RS20880 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.77 ABZR87_RS00835 argininosuccinate synthase low > 80
Ralstonia solanacearum PSI07 0.55 RPSI07_RS02545 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.77 RPSI07_RS12120 argininosuccinate synthase — —
Acidovorax sp. GW101-3H11 0.55 Ac3H11_2345 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (EC 2.1.1.14) 0.77 Ac3H11_2616 Argininosuccinate synthase (EC 6.3.4.5) — —
Ralstonia solanacearum GMI1000 0.55 RS_RS20360 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.77 RS_RS12800 argininosuccinate synthase — —
Ralstonia solanacearum UW163 0.55 UW163_RS18855 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.77 UW163_RS08445 argininosuccinate synthase — —
Ralstonia solanacearum IBSBF1503 0.55 RALBFv3_RS20320 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.77 RALBFv3_RS05180 argininosuccinate synthase — —
Shewanella loihica PV-4 0.55 Shew_2986 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (RefSeq) 0.15 Shew_0205 argininosuccinate synthase (RefSeq) low > 60
Variovorax sp. SCN45 0.55 GFF795 5-methyltetrahydropteroyltriglutamate--homocystei ne methyltransferase (EC 2.1.1.14) 0.77 GFF3096 Argininosuccinate synthase (EC 6.3.4.5) — —
Shewanella sp. ANA-3 0.55 Shewana3_3469 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase (RefSeq) 0.14 Shewana3_3902 argininosuccinate synthase (RefSeq) low > 73
Shewanella oneidensis MR-1 0.55 SO0818 metE 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (NCBI ptt file) 0.14 SO0278 argG argininosuccinate synthase (NCBI ptt file) 0.92 34
Marinobacter adhaerens HP15 0.54 HP15_457 5-methyltetrahydropteroyltriglutamate- homocysteine S-methyltransferase 0.11 HP15_2367 argininosuccinate synthase — —
Burkholderia phytofirmans PsJN 0.52 BPHYT_RS26655 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.13 BPHYT_RS15920 argininosuccinate synthase low > 109
Variovorax sp. OAS795 0.52 ABID97_RS19395 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.76 ABID97_RS21670 argininosuccinate synthase — —
Rhodopseudomonas palustris CGA009 0.52 TX73_012380 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.79 TX73_002040 argininosuccinate synthase — —
Caulobacter crescentus NA1000 0.52 CCNA_00515 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.13 CCNA_00128 argininosuccinate synthase — —
Caulobacter crescentus NA1000 Δfur 0.52 CCNA_00515 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.13 CCNA_00128 argininosuccinate synthase low > 67
Desulfovibrio vulgaris Miyazaki F 0.50 DvMF_2035 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase (RefSeq) 0.16 DvMF_0047 argininosuccinate synthase (RefSeq) low > 51
Desulfovibrio vulgaris Hildenborough JW710 0.49 DVU3371 metE 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase (TIGR) 0.17 DVU1095 argG argininosuccinate synthase (TIGR) low > 55
Rhodospirillum rubrum S1H 0.48 Rru_A1718 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase (NCBI) 0.15 Rru_A3751 Argininosuccinate synthase (NCBI) low > 58
Mycobacterium tuberculosis H37Rv 0.45 Rv1133c Probable 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase MetE (methionine synthase, vitamin-B12 independent isozyme) 0.13 Rv1658 Probable argininosuccinate synthase ArgG — —
Bifidobacterium breve UCC2003 0.42 BBR_RS15405 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.11 BBR_RS13915 argininosuccinate synthase low > 34

Not shown: 14 genomes with orthologs for ECD_03708 only; 21 genomes with orthologs for ECD_03038 only