Conservation of cofitness between CSW01_13865 and CSW01_12340 in Vibrio cholerae E7946 ATCC 55056

66 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_13865 nitrogen regulation protein NR(I) 1.0 CSW01_12340 bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase 0.46 6
Enterobacter asburiae PDN3 0.73 EX28DRAFT_4350 nitrogen regulation protein NR(I) 0.68 EX28DRAFT_3080 rfaE bifunctional protein, domain I/rfaE bifunctional protein, domain II
Enterobacter sp. TBS_079 0.73 MPMX20_04597 DNA-binding transcriptional regulator NtrC 0.69 MPMX20_03889 Bifunctional protein HldE
Serratia liquefaciens MT49 0.72 IAI46_24960 nitrogen regulation protein NR(I) 0.70 IAI46_22055 bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE
Escherichia fergusonii Becca 0.72 EFB2_04748 DNA-binding transcriptional regulator NtrC 0.69 EFB2_00759 Bifunctional protein HldE
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.72 GFF2220 Nitrogen regulation protein NR(I) 0.69 GFF3166 ADP-heptose synthase (EC 2.7.-.-) / D-glycero-beta-D-manno-heptose 7-phosphate kinase low > 78
Escherichia coli ECRC101 0.72 MCAODC_04610 glnG nitrogen regulation protein NR(I) 0.69 MCAODC_09250 hldE bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE
Escherichia coli BW25113 0.72 b3868 glnG fused DNA-binding response regulator in two-component regulatory system with GlnL: response regulator/sigma54 interaction protein (NCBI) 0.69 b3052 rfaE fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) low > 76
Escherichia coli ECRC98 0.72 JDDGAC_17735 glnG nitrogen regulation protein NR(I) 0.69 JDDGAC_22370 hldE bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE
Escherichia coli ECRC102 0.72 NIAGMN_11865 glnG nitrogen regulation protein NR(I) 0.69 NIAGMN_16500 hldE bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE
Escherichia coli ECRC100 0.72 OKFHMN_14110 glnG nitrogen regulation protein NR(I) 0.69 OKFHMN_18735 hldE bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE
Escherichia coli ECRC99 0.72 KEDOAH_14040 glnG nitrogen regulation protein NR(I) 0.69 KEDOAH_09410 hldE bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE
Escherichia coli ECOR27 0.72 NOLOHH_06240 glnG nitrogen regulation protein NR(I) 0.69 NOLOHH_10520 hldE bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE
Escherichia coli Nissle 1917 0.72 ECOLIN_RS22295 nitrogen regulation protein NR(I) 0.69 ECOLIN_RS17615 bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE low > 55
Escherichia coli ECRC62 0.72 BNILDI_05290 glnG nitrogen regulation protein NR(I) 0.69 BNILDI_00995 hldE bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE
Klebsiella pneumoniae MKP103 0.72 KDGMDA_09000 nitrogen regulation protein NR(I) 0.68 KDGMDA_05265 bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE
Escherichia coli ECOR38 0.72 HEPCGN_12740 glnG nitrogen regulation protein NR(I) 0.69 HEPCGN_17590 hldE bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE
Escherichia coli BL21 0.72 ECD_03753 fused DNA-binding response regulator in two-component regulatory system with GlnL: response regulator/sigma54 interaction protein 0.69 ECD_02922 heptose 7-phosphate kinase and heptose 1-phosphate adenyltransferase
Klebsiella michiganensis M5al 0.72 BWI76_RS00385 nitrogen assimilation regulatory protein 0.68 BWI76_RS24455 bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase
Escherichia coli HS(pFamp)R (ATCC 700891) 0.72 OHPLBJKB_04184 DNA-binding transcriptional regulator NtrC 0.69 OHPLBJKB_00652 Bifunctional protein HldE
Rahnella sp. WP5 0.72 EX31_RS15880 nitrogen regulation protein NR(I) 0.69 EX31_RS08140 bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE low > 89
Pantoea sp. MT58 0.72 IAI47_00450 nitrogen regulation protein NR(I) 0.67 IAI47_03105 bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE
Erwinia amylovora T8 0.72 OLJFJH_05495 nitrogen regulation protein NR(I) 0.65 OLJFJH_07645 bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE
Pantoea agglomerans CFBP13505 P0401 0.71 PagCFBP13505_RS18895 nitrogen regulation protein NR(I) 0.67 PagCFBP13505_RS11925 bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE
Pectobacterium carotovorum WPP14 0.71 HER17_RS21440 nitrogen regulation protein NR(I) 0.70 HER17_RS04040 bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE
Dickeya dadantii 3937 0.71 DDA3937_RS00125 nitrogen regulation protein NR(I) 0.68 DDA3937_RS17100 bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE
Dickeya dianthicola 67-19 0.71 HGI48_RS21235 nitrogen regulation protein NR(I) 0.68 HGI48_RS17150 bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE
Dickeya dianthicola ME23 0.71 DZA65_RS22210 nitrogen regulation protein NR(I) 0.68 DZA65_RS18235 bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE
Erwinia tracheiphila SCR3 0.71 LU632_RS22135 glnG nitrogen regulation protein NR(I) 0.69 LU632_RS20670 hldE bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE
Erwinia tracheiphila HP pepo 2.2 0.70 IJEDHG_08285 glnG nitrogen regulation protein NR(I) 0.69 IJEDHG_14390 hldE bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE
Shewanella oneidensis MR-1 0.69 SO4472 ntrC nitrogen regulation protein NR(I) (NCBI ptt file) 0.64 SO3745 rfaE ADP-heptose synthase (NCBI ptt file) low > 76
Shewanella amazonensis SB2B 0.69 Sama_3427 response regulator receiver protein (RefSeq) 0.61 Sama_0731 bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (RefSeq)
Shewanella sp. ANA-3 0.69 Shewana3_0258 nitrogen metabolism transcriptional regulator, NtrC, Fis family (RefSeq) 0.65 Shewana3_0849 bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (RefSeq) low > 73
Shewanella loihica PV-4 0.69 Shew_3561 nitrogen metabolism transcriptional regulator, NtrC, Fis family (RefSeq) 0.63 Shew_0659 bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (RefSeq) low > 60
Pseudomonas fluorescens FW300-N2E3 0.67 AO353_12145 nitrogen regulation protein NR(I) 0.57 AO353_12970 heptose 1-phosphate adenyltransferase
Pseudomonas putida KT2440 0.66 PP_5048 two-component system DNA-binding transcriptional dual regulator GlnL/GlnG 0.56 PP_4934 heptose 7-phosphate kinase/heptose 1-phosphate adenylyltransferase
Pseudomonas lactucae CFBP13502 0.66 GEMAOFIL_00547 DNA-binding transcriptional regulator NtrC 0.58 GEMAOFIL_00699 Bifunctional protein HldE
Pseudomonas simiae WCS417 0.66 PS417_01635 nitrogen regulation protein NR(I) 0.58 PS417_02310 heptose 1-phosphate adenyltransferase
Pseudomonas fluorescens FW300-N2C3 0.66 AO356_09730 nitrogen regulation protein NR(I) 0.57 AO356_08850 heptose 1-phosphate adenyltransferase
Pseudomonas fluorescens GW456-L13 0.66 PfGW456L13_347 Nitrogen regulation protein NR(I) 0.57 PfGW456L13_195 ADP-heptose synthase (EC 2.7.-.-) / D-glycero-beta-D-manno-heptose 7-phosphate kinase
Pseudomonas fluorescens SBW25-INTG 0.66 PFLU_RS01685 nitrogen regulation protein NR(I) 0.58 PFLU_RS02385 bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE
Pseudomonas segetis P6 0.66 MPMX49_04287 DNA-binding transcriptional regulator NtrC 0.59 MPMX49_04194 Bifunctional protein HldE
Pseudomonas fluorescens FW300-N1B4 0.66 Pf1N1B4_1611 Nitrogen regulation protein NR(I) 0.57 Pf1N1B4_1455 ADP-heptose synthase (EC 2.7.-.-) / D-glycero-beta-D-manno-heptose 7-phosphate kinase
Pseudomonas fluorescens SBW25 0.66 PFLU_RS01685 nitrogen regulation protein NR(I) 0.58 PFLU_RS02385 bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE
Pseudomonas fluorescens FW300-N2E2 0.66 Pf6N2E2_3826 Nitrogen regulation protein NR(I) 0.57 Pf6N2E2_3653 ADP-heptose synthase (EC 2.7.-.-) / D-glycero-beta-D-manno-heptose 7-phosphate kinase
Pseudomonas sp. DMC3 0.66 GFF4081 DNA-binding transcriptional regulator NtrC 0.57 GFF3175 Bifunctional protein HldE
Pseudomonas sp. BP01 0.66 JOY50_RS09450 ntrC nitrogen regulation protein NR(I) 0.58 JOY50_RS10025 hldE bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE
Pseudomonas orientalis W4I3 0.66 QF045_RS04705 nitrogen regulation protein NR(I) 0.58 QF045_RS05375 bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE
Pseudomonas syringae pv. syringae B728a 0.66 Psyr_4822 Helix-turn-helix, Fis-type:Nitrogen regulation protein NR(I) 0.57 Psyr_0537 D-alpha,beta-D-heptose 7-phosphate 1-kinase / D-beta-D-heptose 1-phosphate adenylyltransferase
Pseudomonas sp. SVBP6 0.66 COO64_RS13325 ntrC nitrogen regulation protein NR(I) 0.57 COO64_RS17715 hldE bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE
Pseudomonas syringae pv. syringae B728a ΔmexB 0.66 Psyr_4822 Helix-turn-helix, Fis-type:Nitrogen regulation protein NR(I) 0.57 Psyr_0537 D-alpha,beta-D-heptose 7-phosphate 1-kinase / D-beta-D-heptose 1-phosphate adenylyltransferase
Pseudomonas sp. S08-1 0.66 OH686_10640 nitrogen regulation protein NR(I) 0.58 OH686_09595 D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase / D-glycero-beta-D-manno-heptose-7-phosphate kinase
Pseudomonas sp. RS175 0.66 PFR28_04944 DNA-binding transcriptional regulator NtrC 0.57 PFR28_05083 Bifunctional protein HldE
Pseudomonas aeruginosa MRSN321 0.66 DY961_RS11455 ntrC;inference=COORDINATES two-component system response regulator NtrC 0.58 DY961_RS10785 hldE;go_function=nucleotidyltransferase bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE
Pseudomonas aeruginosa PUPa3 0.66 DQ20_RS50645 ntrC;inference=COORDINATES two-component system response regulator NtrC 0.58 DQ20_RS51275 hldE;go_function=nucleotidyltransferase bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE
Pseudomonas aeruginosa PA14 0.66 IKLFDK_27895 two-component system response regulator NtrC 0.58 IKLFDK_28555 bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE
Pseudomonas stutzeri RCH2 0.65 Psest_3932 nitrogen regulation protein NR(I) 0.59 Psest_0470 rfaE bifunctional protein, domain I/rfaE bifunctional protein, domain II
Methylophilus sp. DMC18 0.60 GFF2024 DNA-binding transcriptional regulator NtrC 0.35 GFF295 Bifunctional protein HldE
Xanthobacter sp. DMC5 0.41 GFF848 DNA-binding transcriptional regulator NtrC 0.35 GFF1105 Bifunctional protein HldE
Rhodopseudomonas palustris CGA009 0.40 TX73_013420 nitrogen regulation protein NR(I) 0.31 TX73_020645 D-glycero-beta-D-manno-heptose-7-phosphate kinase
Azospirillum sp. SherDot2 0.40 MPMX19_01112 DNA-binding transcriptional regulator NtrC 0.36 MPMX19_02117 Bifunctional protein HldE
Magnetospirillum magneticum AMB-1 0.40 AMB_RS11950 nitrogen regulation protein NR(I) 0.34 AMB_RS03985 bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase
Azospirillum brasilense Sp245 0.40 AZOBR_RS14430 chemotaxis protein CheY 0.37 AZOBR_RS33905 D-beta-D-heptose 1-phosphate adenosyltransferase low > 97
Rhodospirillum rubrum S1H 0.39 Rru_A1678 Nitrogen Metabolism Transcriptional Regulator, NtrC, Fis Family (NCBI) 0.34 Rru_A0123 RfaE-HldE bifunctional protein, D-beta-D-heptose 7-phosphate kinase, D-beta-D-heptose 1-phosphate adenosyltransferase (NCBI)
Caulobacter crescentus NA1000 0.33 CCNA_03424 AAA-family response regulator tacA 0.34 CCNA_03755 bifunctional D-glycero-D-manno-heptose-7-phosphate 1-kinase/D-glycero-D-manno-heptose-1-phosphate adenylyltransferase low > 66
Caulobacter crescentus NA1000 Δfur 0.33 CCNA_03424 AAA-family response regulator tacA 0.34 CCNA_03755 bifunctional D-glycero-D-manno-heptose-7-phosphate 1-kinase/D-glycero-D-manno-heptose-1-phosphate adenylyltransferase low > 67
Brevundimonas sp. GW460-12-10-14-LB2 0.32 A4249_RS09115 sigma-54 dependent transcriptional regulator 0.34 A4249_RS05620 D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase low > 48

Not shown: 48 genomes with orthologs for CSW01_13865 only; 1 genomes with orthologs for CSW01_12340 only