Conservation of cofitness between CSW01_15165 and CSW01_10080 in Vibrio cholerae E7946 ATCC 55056

69 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_15165 DNA-binding response regulator 1.0 CSW01_10080 4-amino-4-deoxychorismate lyase 0.67 4
Caulobacter crescentus NA1000 Δfur 0.54 CCNA_01351 two-component response regulator protein 0.16 CCNA_03047 4-amino-4-deoxychorismate lyase low > 67
Caulobacter crescentus NA1000 0.54 CCNA_01351 two-component response regulator protein 0.16 CCNA_03047 4-amino-4-deoxychorismate lyase low > 66
Marinobacter adhaerens HP15 0.48 HP15_3484 DNA-binding response regulator 0.17 HP15_2209 4-amino-4-deoxychorismate lyase — —
Azospirillum sp. SherDot2 0.47 MPMX19_00794 Transcriptional activator protein CopR 0.17 MPMX19_04995 D-alanine aminotransferase low > 112
Alteromonas macleodii MIT1002 0.47 MIT1002_03097 Transcriptional activator protein CopR 0.29 MIT1002_01736 Aminodeoxychorismate lyase low > 70
Xanthobacter sp. DMC5 0.45 GFF3127 Transcriptional regulatory protein CusR 0.19 GFF438 D-alanine aminotransferase — —
Lysobacter sp. OAE881 0.44 ABIE51_RS04165 response regulator transcription factor 0.25 ABIE51_RS13925 aminodeoxychorismate lyase low > 62
Acinetobacter baumannii LAC-4 0.44 RR41_RS02755 heavy metal response regulator transcription factor 0.24 RR41_RS04800 aminodeoxychorismate lyase low > 55
Acinetobacter radioresistens SK82 0.44 MPMX26_03114 Transcriptional regulatory protein CusR 0.28 MPMX26_02165 Aminodeoxychorismate lyase low > 36
Pseudomonas fluorescens FW300-N2E3 0.43 AO353_17925 transcriptional regulator 0.24 AO353_01350 4-amino-4-deoxychorismate lyase low > 101
Mucilaginibacter yixingensis YX-36 DSM 26809 0.43 ABZR88_RS15000 response regulator transcription factor 0.13 ABZR88_RS03990 aminotransferase class IV low > 71
Pseudomonas orientalis W4I3 0.43 QF045_RS14560 response regulator transcription factor 0.26 QF045_RS23505 aminodeoxychorismate lyase low > 93
Pseudomonas simiae WCS417 0.42 PS417_11825 transcriptional regulator 0.25 PS417_21425 4-amino-4-deoxychorismate lyase low > 88
Pseudomonas fluorescens SBW25 0.42 PFLU_RS12570 response regulator transcription factor 0.26 PFLU_RS23040 aminodeoxychorismate lyase low > 109
Pseudomonas lactucae CFBP13502 0.42 GEMAOFIL_02648 Transcriptional regulatory protein CusR 0.25 GEMAOFIL_04429 Aminodeoxychorismate lyase low > 96
Pseudomonas sp. BP01 0.42 JOY50_RS14720 heavy metal response regulator transcription factor 0.24 JOY50_RS16775 pabC aminodeoxychorismate lyase low > 84
Rhodanobacter sp000427505 FW510-R12 0.42 LRK53_RS08405 response regulator transcription factor 0.28 LRK53_RS08905 aminodeoxychorismate lyase low > 59
Pseudomonas fluorescens SBW25-INTG 0.42 PFLU_RS12570 response regulator transcription factor 0.26 PFLU_RS23040 aminodeoxychorismate lyase 0.13 73
Pseudomonas putida KT2440 0.42 PP_1438 response regulator 0.23 PP_1917 4-amino-4-deoxychorismate lyase low > 96
Pseudomonas sp. SVBP6 0.42 COO64_RS16580 heavy metal response regulator transcription factor 0.25 COO64_RS05790 pabC aminodeoxychorismate lyase low > 93
Pseudomonas syringae pv. syringae B728a 0.42 Psyr_3127 Response regulator receiver:Transcriptional regulatory protein, C-terminal 0.25 Psyr_1650 aminodeoxychorismate lyase apoprotein low > 86
Rhodanobacter sp. FW510-T8 0.42 OKGIIK_04905 DNA-binding response regulator 0.25 OKGIIK_05735 pabC aminodeoxychorismate lyase low > 53
Pseudomonas syringae pv. syringae B728a ΔmexB 0.42 Psyr_3127 Response regulator receiver:Transcriptional regulatory protein, C-terminal 0.25 Psyr_1650 aminodeoxychorismate lyase apoprotein low > 86
Pseudomonas fluorescens FW300-N2C3 0.42 AO356_23125 transcriptional regulator 0.26 AO356_20180 4-amino-4-deoxychorismate lyase low > 104
Pseudomonas fluorescens FW300-N1B4 0.42 Pf1N1B4_4267 DNA-binding response regulator 0.24 Pf1N1B4_448 Aminodeoxychorismate lyase (EC 4.1.3.38) — —
Agrobacterium fabrum C58 0.41 Atu0629 two component response regulator 0.13 Atu5473 D-alanine aminotransferase low > 89
Pseudomonas fluorescens FW300-N2E2 0.41 Pf6N2E2_504 DNA-binding response regulator 0.25 Pf6N2E2_5955 Aminodeoxychorismate lyase (EC 4.1.3.38) low > 103
Pseudomonas sp. S08-1 0.41 OH686_22680 Copper-sensing two-component system response regulator CusR 0.28 OH686_22155 aminodeoxychorismate lyase low > 80
Rhodanobacter denitrificans FW104-10B01 0.41 LRK54_RS08060 response regulator transcription factor 0.26 LRK54_RS01165 aminodeoxychorismate lyase low > 59
Enterobacter asburiae PDN3 0.41 EX28DRAFT_1165 heavy metal response regulator 0.33 EX28DRAFT_1833 aminodeoxychorismate lyase low > 76
Rhodanobacter denitrificans MT42 0.41 LRK55_RS07810 response regulator transcription factor 0.26 LRK55_RS00940 aminodeoxychorismate lyase low > 63
Klebsiella pneumoniae MKP103 0.41 KDGMDA_00710 copper/silver response regulator transcription factor SilR 0.31 KDGMDA_18710 aminodeoxychorismate lyase low > 95
Pseudomonas sp. DMC3 0.41 GFF1578 Transcriptional regulatory protein CusR 0.26 GFF4754 Aminodeoxychorismate lyase low > 89
Dickeya dianthicola ME23 0.41 DZA65_RS03595 copper/silver response regulator transcription factor SilR 0.32 DZA65_RS13640 aminodeoxychorismate lyase low > 75
Pseudomonas segetis P6 0.41 ACVTMO_RS00395 heavy metal response regulator transcription factor 0.28 ACVTMO_RS10325 pabC aminodeoxychorismate lyase low > 75
Dickeya dianthicola 67-19 0.40 HGI48_RS03485 heavy metal response regulator transcription factor 0.33 HGI48_RS13170 aminodeoxychorismate lyase low > 71
Shewanella loihica PV-4 0.40 Shew_0097 two component transcriptional regulator (RefSeq) 0.26 Shew_1577 aminotransferase, class IV (RefSeq) low > 60
Pedobacter sp. GW460-11-11-14-LB5 0.40 CA265_RS04655 DNA-binding response regulator 0.14 CA265_RS14410 4-amino-4-deoxychorismate lyase low > 88
Pseudomonas aeruginosa PUPa3 0.40 DQ20_RS32585 heavy metal response regulator transcription factor 0.27 DQ20_RS33430 pabC;go_function=4-amino-4-deoxychorismate aminodeoxychorismate lyase low > 101
Pseudomonas aeruginosa MRSN321 0.40 DY961_RS03005 heavy metal response regulator transcription factor 0.27 DY961_RS02155 pabC;go_function=4-amino-4-deoxychorismate aminodeoxychorismate lyase low > 100
Enterobacter sp. TBS_079 0.40 MPMX20_02319 Transcriptional regulatory protein CusR 0.28 MPMX20_01776 Aminodeoxychorismate lyase low > 85
Shewanella sp. ANA-3 0.40 Shewana3_4296 DNA-binding transcriptional activator CusR (RefSeq) 0.28 Shewana3_1764 aminodeoxychorismate lyase apoprotein (RefSeq) — —
Pseudomonas aeruginosa PA14 0.40 IKLFDK_14215 DNA-binding response regulator 0.28 IKLFDK_15080 aminodeoxychorismate lyase — —
Pseudomonas stutzeri RCH2 0.40 Psest_0611 heavy metal response regulator 0.27 Psest_1691 aminodeoxychorismate lyase low > 67
Pseudomonas fluorescens GW456-L13 0.40 PfGW456L13_4017 Copper-sensing two-component system response regulator CusR 0.26 PfGW456L13_2108 Aminodeoxychorismate lyase (EC 4.1.3.38) low > 87
Kangiella aquimarina DSM 16071 0.39 B158DRAFT_1663 heavy metal response regulator 0.22 B158DRAFT_1750 aminodeoxychorismate lyase low > 40
Fusobacterium nucleatum SB010 0.39 HUW76_07205 response regulator transcription factor 0.14 HUW76_10200 aminotransferase class IV low > 35
Escherichia coli BW25113 0.39 b0571 cusR DNA-binding response regulator in two-component regulatory system with CusS (NCBI) 0.33 b1096 pabC 4-amino-4-deoxychorismate lyase (NCBI) low > 76
Shewanella oneidensis MR-1 0.39 SO4428 DNA-binding response regulator (NCBI ptt file) 0.29 SO2615 pabC 4-amino-4-deoxychorismate lyase (NCBI ptt file) low > 76
Escherichia coli ECRC62 0.39 BNILDI_22095 cusR copper response regulator transcription factor CusR 0.33 BNILDI_19250 pabC aminodeoxychorismate lyase low > 75
Escherichia coli ECRC100 0.39 OKFHMN_07705 cusR copper response regulator transcription factor CusR 0.33 OKFHMN_03560 pabC aminodeoxychorismate lyase low > 79
Escherichia coli ECRC101 0.39 MCAODC_26920 cusR copper response regulator transcription factor CusR 0.33 MCAODC_22920 pabC aminodeoxychorismate lyase low > 87
Escherichia coli ECRC102 0.39 NIAGMN_05760 cusR copper response regulator transcription factor CusR 0.33 NIAGMN_24270 pabC aminodeoxychorismate lyase — —
Escherichia coli Nissle 1917 0.39 ECOLIN_RS03125 copper response regulator transcription factor CusR 0.33 ECOLIN_RS06330 aminodeoxychorismate lyase — —
Escherichia fergusonii Becca 0.39 EFB2_03523 Transcriptional regulatory protein CusR 0.33 EFB2_02879 Aminodeoxychorismate lyase low > 86
Escherichia coli ECOR38 0.39 HEPCGN_00585 cusR copper response regulator transcription factor CusR 0.32 HEPCGN_23920 pabC aminodeoxychorismate lyase low > 88
Escherichia coli ECOR27 0.39 NOLOHH_24085 cusR copper response regulator transcription factor CusR 0.33 NOLOHH_21090 pabC aminodeoxychorismate lyase low > 76
Escherichia coli ECRC98 0.39 JDDGAC_11350 cusR copper response regulator transcription factor CusR 0.33 JDDGAC_07220 pabC aminodeoxychorismate lyase low > 87
Escherichia coli ECRC99 0.39 KEDOAH_20265 cusR copper response regulator transcription factor CusR 0.33 KEDOAH_24195 pabC aminodeoxychorismate lyase — —
Escherichia coli BL21 0.39 ECD_00532 response regulator in two-component regulatory system with CusS 0.33 ECD_01092 4-amino-4-deoxychorismate lyase component of para-aminobenzoate synthase multienzyme complex — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.39 OHPLBJKB_03138 Transcriptional regulatory protein CusR 0.33 OHPLBJKB_02570 Aminodeoxychorismate lyase low > 74
Serratia liquefaciens MT49 0.39 IAI46_16745 heavy metal response regulator transcription factor 0.33 IAI46_09805 aminodeoxychorismate lyase low > 87
Dyella japonica UNC79MFTsu3.2 0.38 ABZR86_RS12570 response regulator transcription factor 0.24 ABZR86_RS06150 aminodeoxychorismate lyase low > 74
Synechocystis sp000284455 PCC 6803 0.38 SGL_RS14385 response regulator transcription factor 0.12 SGL_RS07250 aminotransferase class IV low > 52
Pectobacterium carotovorum WPP14 0.38 HER17_RS13650 heavy metal response regulator transcription factor 0.33 HER17_RS08665 aminodeoxychorismate lyase low > 75
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.36 GFF3273 Putative two-component system response regulator YedW 0.29 GFF3378 Aminodeoxychorismate lyase (EC 4.1.3.38) low > 78
Pantoea agglomerans CFBP13505 P0401 0.36 PagCFBP13505_RS14010 response regulator transcription factor HprR 0.28 PagCFBP13505_RS05280 aminodeoxychorismate lyase low > 74
Dickeya dadantii 3937 0.34 DDA3937_RS03385 heavy metal response regulator transcription factor 0.32 DDA3937_RS23255 aminodeoxychorismate lyase low > 74
Klebsiella michiganensis M5al 0.32 BWI76_RS18590 DNA-binding response regulator 0.32 BWI76_RS11105 aminodeoxychorismate lyase low > 92

Not shown: 33 genomes with orthologs for CSW01_15165 only; 7 genomes with orthologs for CSW01_10080 only