Conservation of cofitness between CSW01_12035 and CSW01_05660 in Vibrio cholerae E7946 ATCC 55056

62 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_12035 glutamate synthase small subunit 1.0 CSW01_05660 dethiobiotin synthase 0.65 3
Dickeya dianthicola 67-19 0.78 HGI48_RS01555 glutamate synthase small subunit 0.46 HGI48_RS08690 ATP-dependent dethiobiotin synthetase BioD low > 71
Enterobacter asburiae PDN3 0.78 EX28DRAFT_3276 glutamate synthase small subunit family protein, proteobacterial 0.45 EX28DRAFT_1492 dethiobiotin synthase low > 76
Pectobacterium carotovorum WPP14 0.78 HER17_RS19915 glutamate synthase small subunit 0.47 HER17_RS10730 dethiobiotin synthase low > 75
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.78 GFF2957 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) 0.47 GFF1784 Dethiobiotin synthetase (EC 6.3.3.3) low > 78
Dickeya dianthicola ME23 0.78 DZA65_RS01630 FAD-dependent oxidoreductase 0.46 DZA65_RS08980 ATP-dependent dethiobiotin synthetase BioD low > 75
Enterobacter sp. TBS_079 0.78 MPMX20_04127 Glutamate synthase [NADPH] small chain 0.46 MPMX20_02064 ATP-dependent dethiobiotin synthetase BioD 1 low > 85
Dickeya dadantii 3937 0.78 DDA3937_RS01660 FAD-dependent oxidoreductase 0.45 DDA3937_RS10680 ATP-dependent dethiobiotin synthetase BioD low > 74
Rahnella sp. WP5 0.78 EX31_RS12510 FAD-dependent oxidoreductase 0.42 EX31_RS23710 ATP-dependent dethiobiotin synthetase BioD low > 89
Serratia liquefaciens MT49 0.78 IAI46_22350 glutamate synthase small subunit 0.45 IAI46_06540 ATP-dependent dethiobiotin synthetase BioD low > 87
Escherichia coli ECRC101 0.77 MCAODC_08400 gltD glutamate synthase subunit GltD 0.47 MCAODC_17665 bioD dethiobiotin synthase — —
Escherichia coli ECRC98 0.77 JDDGAC_21505 gltD glutamate synthase subunit GltD 0.47 JDDGAC_02335 bioD dethiobiotin synthase low > 87
Escherichia coli ECOR38 0.77 HEPCGN_16755 gltD glutamate synthase subunit GltD 0.47 HEPCGN_06120 bioD dethiobiotin synthase low > 88
Escherichia coli ECRC99 0.77 KEDOAH_10270 gltD glutamate synthase subunit GltD 0.47 KEDOAH_00360 bioD dethiobiotin synthase — —
Escherichia coli ECRC102 0.77 NIAGMN_15640 gltD glutamate synthase subunit GltD 0.47 NIAGMN_00330 bioD dethiobiotin synthase low > 80
Escherichia coli ECRC100 0.77 OKFHMN_17880 gltD glutamate synthase subunit GltD 0.47 OKFHMN_27745 bioD dethiobiotin synthase — —
Klebsiella pneumoniae MKP103 0.77 KDGMDA_06150 Glutamate synthase [NADPH] small chain 0.47 KDGMDA_21235 dethiobiotin synthase low > 94
Escherichia coli BW25113 0.77 b3213 gltD glutamate synthase, 4Fe-4S protein, small subunit (NCBI) 0.47 b1593 b1593 orf, hypothetical protein (VIMSS) low > 76
Escherichia fergusonii Becca 0.77 EFB2_00610 Glutamate synthase [NADPH] small chain 0.47 EFB2_02399 ATP-dependent dethiobiotin synthetase BioD 1 0.36 11
Escherichia coli ECOR27 0.77 NOLOHH_09680 gltD glutamate synthase subunit GltD 0.47 NOLOHH_18250 bioD dethiobiotin synthase — —
Klebsiella pneumoniae MRSN742743 0.77 GJGHJB_00482 gltD Glutamate synthase [NADPH] small chain 0.47 GJGHJB_02596 bioD dethiobiotin synthase low > 83
Escherichia coli ECRC62 0.77 BNILDI_01855 gltD glutamate synthase subunit GltD 0.47 BNILDI_17040 bioD dethiobiotin synthase low > 75
Escherichia coli Nissle 1917 0.77 ECOLIN_RS18480 glutamate synthase subunit GltD 0.47 ECOLIN_RS08900 dethiobiotin synthase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.77 OHPLBJKB_00487 Glutamate synthase [NADPH] small chain 0.47 OHPLBJKB_02133 ATP-dependent dethiobiotin synthetase BioD 1 low > 74
Escherichia coli BL21 0.77 ECD_03078 glutamate synthase, 4Fe-4S protein, small subunit 0.47 ECD_01562 putative dethiobiotin synthetase low > 61
Klebsiella michiganensis M5al 0.77 BWI76_RS25320 glutamate synthase 0.46 BWI76_RS15950 dethiobiotin synthase low > 92
Erwinia tracheiphila HP pepo 2.2 0.76 IJEDHG_13700 glutamate synthase small subunit 0.43 IJEDHG_23285 bioD dethiobiotin synthase low > 61
Erwinia tracheiphila SCR3 0.76 LU632_RS21320 glutamate synthase small subunit 0.43 LU632_RS12300 bioD dethiobiotin synthase low > 73
Alteromonas macleodii MIT1002 0.75 MIT1002_03140 Glutamate synthase [NADPH] small chain 0.32 MIT1002_01382 ATP-dependent dethiobiotin synthetase BioD 1 low > 70
Pseudomonas aeruginosa PA14 0.70 IKLFDK_28360 glutamate synthase small subunit 0.30 IKLFDK_22915 dethiobiotin synthase 0.69 63
Pseudomonas aeruginosa MRSN321 0.70 PFGADD_05273 gltD Glutamate synthase (NADPH/NADH) small chain 0.30 PFGADD_00513 bioD dethiobiotin synthase — —
Pseudomonas aeruginosa PUPa3 0.70 NPBIFN_05349 gltD Glutamate synthase (NADPH/NADH) small chain 0.30 NPBIFN_00516 bioD dethiobiotin synthase — —
Pseudomonas fluorescens FW300-N2C3 0.69 AO356_09370 glutamate synthase 0.37 AO356_14155 dethiobiotin synthetase low > 104
Pseudomonas sp. RS175 0.69 PFR28_05016 Glutamate synthase [NADPH] small chain 0.37 PFR28_04099 ATP-dependent dethiobiotin synthetase BioD 1 — —
Pseudomonas fluorescens GW456-L13 0.69 PfGW456L13_271 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) 0.38 PfGW456L13_1151 Dethiobiotin synthetase (EC 6.3.3.3) low > 87
Pseudomonas sp. DMC3 0.69 GFF3103 Glutamate synthase [NADPH] small chain 0.39 GFF72 ATP-dependent dethiobiotin synthetase BioD 1 low > 89
Pseudomonas fluorescens FW300-N1B4 0.69 Pf1N1B4_1533 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) 0.37 Pf1N1B4_2491 Dethiobiotin synthetase (EC 6.3.3.3) low > 87
Pseudomonas fluorescens FW300-N2E2 0.69 Pf6N2E2_3751 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) 0.36 Pf6N2E2_4764 Dethiobiotin synthetase (EC 6.3.3.3) 0.34 78
Pseudomonas syringae pv. syringae B728a ΔmexB 0.69 Psyr_0412 glutamate synthase (NADPH) small subunit 0.35 Psyr_4683 dethiobiotin synthase low > 86
Pseudomonas syringae pv. syringae B728a 0.69 Psyr_0412 glutamate synthase (NADPH) small subunit 0.35 Psyr_4683 dethiobiotin synthase low > 86
Pseudomonas protegens RBAN4 0.69 FABNJH_02370 gltD NADPH-dependent glutamate synthase beta chain or related oxidoreductase 0.37 FABNJH_28655 bioD dethiobiotin synthase — —
Pseudomonas fluorescens FW300-N2E3 0.69 AO353_12520 glutamate synthase 0.36 AO353_07505 dethiobiotin synthetase 0.44 64
Shewanella sp. ANA-3 0.69 Shewana3_3051 gltD glutamate synthase subunit beta (RefSeq) 0.38 Shewana3_2516 bioD dithiobiotin synthetase (RefSeq) — —
Pseudomonas sp. S08-1 0.69 OH686_10000 Glutamate synthase [NADPH] small chain 0.34 OH686_10335 dethiobiotin synthase low > 80
Pseudomonas fluorescens SBW25-INTG 0.69 PFLU_RS02050 NAD(P)-binding protein 0.38 PFLU_RS27630 dethiobiotin synthase low > 109
Shewanella oneidensis MR-1 0.69 SO1324 gltD glutamate synthase, small subunit (NCBI ptt file) 0.38 SO2737 bioD dethiobiotin synthase (NCBI ptt file) — —
Pseudomonas fluorescens SBW25 0.69 PFLU_RS02050 NAD(P)-binding protein 0.38 PFLU_RS27630 dethiobiotin synthase low > 109
Pseudomonas sp. SVBP6 0.69 COO64_RS13090 FAD-dependent oxidoreductase 0.40 COO64_RS22705 bioD dethiobiotin synthase low > 91
Pseudomonas stutzeri RCH2 0.69 Psest_3710 glutamate synthase small subunit family protein, proteobacterial 0.34 Psest_0415 dethiobiotin synthase low > 67
Pseudomonas lactucae CFBP13502 0.69 GEMAOFIL_00633 Glutamate synthase [NADPH] small chain 0.36 GEMAOFIL_05318 ATP-dependent dethiobiotin synthetase BioD 1 low > 96
Pseudomonas simiae WCS417 0.69 PS417_02005 glutamate synthase 0.38 PS417_25985 dethiobiotin synthetase low > 88
Pseudomonas orientalis W4I3 0.69 QF045_RS05065 FAD-dependent oxidoreductase 0.37 QF045_RS00395 dethiobiotin synthase low > 93
Pseudomonas sp. FW215-L2 0.69 GFF1057 Glutamate synthase [NADPH] small chain 0.38 GFF76 ATP-dependent dethiobiotin synthetase BioD 1 low > 111
Pseudomonas sp. BP01 0.68 JOY50_RS09325 FAD-dependent oxidoreductase 0.41 JOY50_RS17950 bioD dethiobiotin synthase 0.88 49
Pseudomonas putida KT2440 0.68 PP_5075 glutamate synthase (NADPH) beta subunit 0.42 PP_0366 dethiobiotin synthetase low > 96
Marinobacter adhaerens HP15 0.68 HP15_483 oxidoreductase Fe-S binding subunit 0.37 HP15_2482 dethiobiotin synthetase — —
Shewanella amazonensis SB2B 0.68 Sama_0856 gltD glutamate synthase subunit beta (RefSeq) 0.35 Sama_1441 bioD dithiobiotin synthetase (RefSeq) — —
Shewanella loihica PV-4 0.68 Shew_1031 gltD glutamate synthase subunit beta (RefSeq) 0.36 Shew_1722 dethiobiotin synthase (RefSeq) — —
Pseudomonas segetis P6 0.68 ACVTMO_RS20980 FAD-dependent oxidoreductase 0.40 ACVTMO_RS03780 bioD dethiobiotin synthase low > 75
Lysobacter sp. OAE881 0.57 ABIE51_RS01315 FAD-dependent oxidoreductase 0.33 ABIE51_RS17990 dethiobiotin synthase low > 62
Dyella japonica UNC79MFTsu3.2 0.54 ABZR86_RS16800 FAD-dependent oxidoreductase 0.37 ABZR86_RS12700 dethiobiotin synthase low > 74
Rhodanobacter denitrificans FW104-10B01 0.53 LRK54_RS10965 FAD-dependent oxidoreductase 0.33 LRK54_RS07180 dethiobiotin synthase low > 59
Rhodanobacter denitrificans MT42 0.53 LRK55_RS10670 FAD-dependent oxidoreductase 0.32 LRK55_RS06915 dethiobiotin synthase low > 63

Not shown: 16 genomes with orthologs for CSW01_12035 only; 24 genomes with orthologs for CSW01_05660 only