Conservation of cofitness between BWI76_RS19375 and BWI76_RS10710 in Klebsiella michiganensis M5al

50 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS19375 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 1.0 BWI76_RS10710 Glutamate--putrescine ligase (EC 6.3.1.11) (from data) 0.20 16
Escherichia coli ECRC100 0.93 OKFHMN_24075 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.95 OKFHMN_02445 puuA glutamate-putrescine ligase low > 80
Escherichia coli ECRC99 0.93 KEDOAH_04075 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.95 KEDOAH_26330 puuA glutamate-putrescine ligase — —
Escherichia coli ECRC98 0.93 JDDGAC_28185 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.95 JDDGAC_04990 puuA glutamate-putrescine ligase low > 86
Escherichia coli ECRC101 0.93 MCAODC_21085 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.95 MCAODC_15825 puuA glutamate-putrescine ligase low > 87
Escherichia coli ECRC102 0.93 NIAGMN_22020 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.95 NIAGMN_26615 puuA glutamate-putrescine ligase — —
Escherichia coli ECRC62 0.93 BNILDI_14330 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.95 BNILDI_18280 puuA glutamate-putrescine ligase low > 75
Escherichia coli HS(pFamp)R (ATCC 700891) 0.93 OHPLBJKB_01607 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.94 OHPLBJKB_02385 Gamma-glutamylputrescine synthetase PuuA low > 73
Escherichia coli BW25113 0.93 b2103 thiD phosphomethylpyrimidine kinase (NCBI) 0.95 b1297 b1297 putative glutamine synthetase (EC 6.3.1.2) (VIMSS) low > 76
Escherichia coli ECOR27 0.93 NOLOHH_15415 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.95 NOLOHH_20130 puuA glutamate-putrescine ligase low > 75
Escherichia coli BL21 0.92 ECD_02031 hydroxy-methylpyrimidine kinase and hydroxy-phosphomethylpyrimidine kinase 0.94 ECD_01274 glutamate--putrescine ligase low > 61
Escherichia coli ECOR38 0.92 HEPCGN_02760 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.94 HEPCGN_25755 puuA glutamate-putrescine ligase low > 87
Enterobacter sp. TBS_079 0.90 MPMX20_03076 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.39 MPMX20_03117 Gamma-glutamylputrescine synthetase PuuA low > 85
Enterobacter asburiae PDN3 0.90 EX28DRAFT_0469 hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.95 EX28DRAFT_1498 Glutamine synthetase low > 76
Serratia liquefaciens MT49 0.77 IAI46_19100 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.84 IAI46_10560 glutamine synthetase low > 86
Rahnella sp. WP5 0.77 EX31_RS20390 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.76 EX31_RS17895 glutamine synthetase low > 89
Pantoea sp. MT58 0.75 IAI47_06810 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.74 IAI47_07125 glutamine synthetase low > 76
Paraburkholderia sabiae LMG 24235 0.54 QEN71_RS06305 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.25 QEN71_RS12935 glutamine synthetase family protein — —
Paraburkholderia bryophila 376MFSha3.1 0.54 H281DRAFT_00587 hydroxymethylpyrimidine kinase /phosphomethylpyrimidine kinase 0.25 H281DRAFT_01081 L-glutamine synthetase — —
Burkholderia phytofirmans PsJN 0.52 BPHYT_RS12250 phosphomethylpyrimidine kinase 0.25 BPHYT_RS23160 Gamma-glutamyl-putrescine synthetase (EC 6.3.1.11) (from data) — —
Paraburkholderia graminis OAS925 0.50 ABIE53_002529 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.26 ABIE53_002230 glutamine synthetase — —
Rhizobium sp. OAE497 0.50 ABIE40_RS25930 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.27 ABIE40_RS05855 glutamine synthetase family protein low > 107
Rhodopseudomonas palustris CGA009 0.48 TX73_020570 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.17 TX73_007190 glutamine synthetase family protein — —
Agrobacterium fabrum C58 0.46 Atu3290 phosphomethylpyrimidine kinase 0.32 Atu0193 glutamine synthetase low > 89
Sinorhizobium meliloti 1021 0.42 SM_b20962 phoshomethylpyrimidine kinase 0.30 SMc01973 glutamine synthetase low > 103
Hydrogenophaga sp. GW460-11-11-14-LB1 0.38 GFF249 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) 0.23 GFF2037 glutamine synthetase family protein low > 90
Dinoroseobacter shibae DFL-12 0.38 Dshi_0915 phosphomethylpyrimidine kinase (RefSeq) 0.25 Dshi_2226 Glutamate--putrescine ligase (RefSeq) low > 64
Rhodospirillum rubrum S1H 0.37 Rru_A1102 Phosphomethylpyrimidine kinase (NCBI) 0.28 Rru_A1253 Glutamine synthetase, catalytic region (NCBI) — —
Azospirillum brasilense Sp245 0.36 AZOBR_RS07045 phosphomethylpyrimidine kinase 0.25 AZOBR_RS08850 glutamine synthetase — —
Pedobacter sp. GW460-11-11-14-LB5 0.34 CA265_RS24160 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.17 CA265_RS24865 glutamine synthetase low > 88
Azospirillum sp. SherDot2 0.34 MPMX19_06182 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.25 MPMX19_04886 Gamma-glutamylputrescine synthetase PuuA — —
Mucilaginibacter yixingensis YX-36 DSM 26809 0.31 ABZR88_RS08810 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.17 ABZR88_RS10470 glutamine synthetase family protein low > 71
Caulobacter crescentus NA1000 Δfur 0.31 CCNA_03331 phosphomethylpyrimidine kinase/hydroxymethylpyrimidine kinase 0.34 CCNA_03240 glutamine synthetase — —
Caulobacter crescentus NA1000 0.31 CCNA_03331 phosphomethylpyrimidine kinase/hydroxymethylpyrimidine kinase 0.34 CCNA_03240 glutamine synthetase — —
Xanthomonas campestris pv. campestris strain 8004 0.30 Xcc-8004.3091.1 hypothetical protein 0.37 Xcc-8004.2202.1 glutamine synthetase family protein low > 74
Mycobacterium tuberculosis H37Rv 0.24 Rv0422c Probable phosphomethylpyrimidine kinase ThiD (HMP-phosphate kinase) (HMP-P kinase) 0.17 Rv2860c Probable glutamine synthetase GlnA4 (glutamine synthase) (GS-II) — —
Pseudomonas fluorescens SBW25-INTG 0.24 PFLU_RS26530 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.39 PFLU_RS28795 glutamine synthetase low > 109
Pseudomonas fluorescens SBW25 0.24 PFLU_RS26530 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.39 PFLU_RS28795 glutamine synthetase low > 109
Pseudomonas simiae WCS417 0.23 PS417_24600 hydrogenase 0.40 PS417_27140 Gamma-glutamyl-putrescine synthetase (EC 6.3.1.11) (from data) low > 88
Pseudomonas putida KT2440 0.22 PP_4782 Phosphomethylpyrimidine kinase 0.40 PP_5299 glutamate-putrescine ligase low > 96
Pseudomonas fluorescens GW456-L13 0.22 PfGW456L13_1385 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) 0.40 PfGW456L13_925 Gamma-glutamyl-putrescine synthetase (EC 6.3.1.11) (from data) low > 87
Pseudomonas fluorescens FW300-N2E3 0.22 AO353_06350 hydrogenase 0.40 AO353_29300 gamma-glutamylputrescine synthetase low > 101
Pseudomonas fluorescens FW300-N2C3 0.22 AO356_15435 hydrogenase 0.40 AO356_13135 Gamma-glutamyl-putrescine synthetase (EC 6.3.1.11) (from data) low > 104
Pseudomonas stutzeri RCH2 0.21 Psest_0537 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.40 Psest_4288 Glutamate--putrescine ligase (EC 6.3.1.11) (from data) low > 67
Pseudomonas syringae pv. syringae B728a 0.21 Psyr_4340 phosphomethylpyrimidine kinase, putative 0.40 Psyr_4868 glutamate--putrescine ligase low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.21 Psyr_4340 phosphomethylpyrimidine kinase, putative 0.40 Psyr_4868 glutamate--putrescine ligase low > 86
Acinetobacter radioresistens SK82 0.21 MPMX26_02438 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.42 MPMX26_02239 Gamma-glutamylputrescine synthetase PuuA — —
Pseudomonas sp. RS175 0.20 PFR28_03843 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.40 PFR28_04298 Gamma-glutamylputrescine synthetase PuuA low > 88
Pseudomonas fluorescens FW300-N1B4 0.18 Pf1N1B4_2718 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) 0.40 Pf1N1B4_4354 Gamma-glutamyl-putrescine synthetase (EC 6.3.1.11) low > 87
Pseudomonas fluorescens FW300-N2E2 0.18 Pf6N2E2_5024 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) 0.37 Pf6N2E2_4509 Gamma-glutamyl-putrescine synthetase (EC 6.3.1.11) (from data) low > 103
Phaeobacter inhibens DSM 17395 0.17 PGA1_c09030 phosphomethylpyrimidine kinase ThiD 0.27 PGA1_c11540 gamma-glutamylputrescine synthetase PuuA low > 62

Not shown: 38 genomes with orthologs for BWI76_RS19375 only; 6 genomes with orthologs for BWI76_RS10710 only