Conservation of cofitness between BNILDI_14455 and BNILDI_22760 in Escherichia coli ECRC62

55 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli ECRC62 1.0 BNILDI_14455 mdtB multidrug efflux RND transporter permease subunit MdtB 1.0 BNILDI_22760 panE 2-dehydropantoate 2-reductase 0.76 2
Escherichia coli ECRC99 1.00 KEDOAH_03955 mdtB multidrug efflux RND transporter permease subunit MdtB 0.99 KEDOAH_19570 panE 2-dehydropantoate 2-reductase — —
Escherichia coli ECOR27 1.00 NOLOHH_15540 mdtB multidrug efflux RND transporter permease subunit MdtB 0.99 NOLOHH_01345 panE 2-dehydropantoate 2-reductase low > 75
Escherichia coli Nissle 1917 1.00 ECOLIN_RS12200 multidrug efflux RND transporter permease subunit MdtB 0.98 ECOLIN_RS02560 2-dehydropantoate 2-reductase low > 55
Escherichia coli ECRC100 1.00 OKFHMN_24195 mdtB multidrug efflux RND transporter permease subunit MdtB 0.99 OKFHMN_08395 panE 2-dehydropantoate 2-reductase low > 80
Escherichia coli ECRC101 1.00 MCAODC_20745 mdtB multidrug efflux RND transporter permease subunit MdtB 0.99 MCAODC_27620 panE 2-dehydropantoate 2-reductase low > 87
Escherichia coli ECRC102 1.00 NIAGMN_22140 mdtB multidrug efflux RND transporter permease subunit MdtB 0.99 NIAGMN_06450 panE 2-dehydropantoate 2-reductase — —
Escherichia coli ECRC98 1.00 JDDGAC_28305 mdtB multidrug efflux RND transporter permease subunit MdtB 0.99 JDDGAC_12050 panE 2-dehydropantoate 2-reductase low > 86
Escherichia coli BW25113 1.00 b2075 mdtB multidrug efflux system, subunit B (NCBI) 1.00 b0425 panE 2-dehydropantoate 2-reductase (NCBI) low > 76
Escherichia fergusonii Becca 1.00 EFB2_01780 Multidrug resistance protein MdtB 0.99 EFB2_03632 2-dehydropantoate 2-reductase low > 86
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_01629 Multidrug resistance protein MdtB 1.00 OHPLBJKB_03251 2-dehydropantoate 2-reductase low > 73
Escherichia coli BL21 0.99 ECD_01980 multidrug efflux system, subunit B 0.99 ECD_00373 2-dehydropantoate reductase, NADPH-specific low > 61
Escherichia coli ECOR38 0.99 HEPCGN_02885 mdtB multidrug efflux RND transporter permease subunit MdtB 0.99 HEPCGN_07025 panE 2-dehydropantoate 2-reductase low > 87
Klebsiella michiganensis M5al 0.90 BWI76_RS19255 multidrug transporter subunit MdtB 0.79 BWI76_RS06405 2-dehydropantoate 2-reductase low > 92
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.90 GFF3854 Multidrug transporter MdtB 0.80 GFF4336 2-dehydropantoate 2-reductase (EC 1.1.1.169) low > 78
Enterobacter sp. TBS_079 0.89 MPMX20_03061 Multidrug resistance protein MdtB 0.85 MPMX20_01016 2-dehydropantoate 2-reductase low > 85
Enterobacter asburiae PDN3 0.89 EX28DRAFT_0483 Cation/multidrug efflux pump 0.85 EX28DRAFT_2546 2-dehydropantoate 2-reductase low > 76
Serratia liquefaciens MT49 0.81 IAI46_18975 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.66 IAI46_04950 2-dehydropantoate 2-reductase low > 86
Pantoea sp. MT58 0.80 IAI47_06870 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.66 IAI47_14715 2-dehydropantoate 2-reductase low > 76
Erwinia tracheiphila SCR3 0.79 LU632_RS08690 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.61 LU632_RS18455 panE 2-dehydropantoate 2-reductase low > 74
Pectobacterium carotovorum WPP14 0.79 HER17_RS06320 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.61 HER17_RS15910 2-dehydropantoate 2-reductase low > 75
Dickeya dadantii 3937 0.77 DDA3937_RS15265 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.58 DDA3937_RS05555 2-dehydropantoate 2-reductase low > 74
Dickeya dianthicola ME23 0.77 DZA65_RS16165 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.59 DZA65_RS05940 2-dehydropantoate 2-reductase low > 75
Dickeya dianthicola 67-19 0.76 HGI48_RS15345 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.59 HGI48_RS05615 2-dehydropantoate 2-reductase low > 71
Herbaspirillum seropedicae SmR1 0.68 HSERO_RS07650 multidrug transporter 0.17 HSERO_RS09230 2-dehydropantoate 2-reductase low > 78
Ralstonia solanacearum UW163 0.65 UW163_RS21010 multidrug transporter subunit MdtB 0.08 UW163_RS03340 2-dehydropantoate 2-reductase — —
Ralstonia solanacearum IBSBF1503 0.65 RALBFv3_RS18120 multidrug transporter subunit MdtB 0.08 RALBFv3_RS10240 2-dehydropantoate 2-reductase low > 76
Ralstonia solanacearum GMI1000 0.65 RS_RS22915 multidrug transporter subunit MdtB 0.09 RS_RS00860 2-dehydropantoate 2-reductase low > 80
Ralstonia sp. UNC404CL21Col 0.65 ABZR87_RS19025 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.15 ABZR87_RS15450 2-dehydropantoate 2-reductase low > 80
Cupriavidus basilensis FW507-4G11 0.64 RR42_RS03310 multidrug transporter 0.13 RR42_RS32960 2-dehydropantoate 2-reductase low > 128
Pseudomonas sp. RS175 0.63 PFR28_02194 Multidrug resistance protein MdtB 0.23 PFR28_03426 2-dehydropantoate 2-reductase low > 88
Pseudomonas fluorescens FW300-N2C3 0.62 AO356_25875 multidrug transporter 0.23 AO356_17955 2-dehydropantoate 2-reductase low > 104
Pseudomonas putida KT2440 0.62 PP_3584 multidrug efflux transport system - membrane subunit 0.22 PP_1351 putative 2-dehydropantoate 2-reductase low > 96
Pseudomonas fluorescens FW300-N2E2 0.62 Pf6N2E2_1272 Acriflavin resistance plasma membrane protein 0.23 Pf6N2E2_5521 2-dehydropantoate 2-reductase (EC 1.1.1.169) low > 103
Rahnella sp. WP5 0.62 EX31_RS13380 MMPL family transporter 0.58 EX31_RS22180 2-dehydropantoate 2-reductase low > 89
Pseudomonas sp. S08-1 0.62 OH686_00925 Multidrug efflux system MdtABC-TolC, inner-membrane proton/drug antiporter MdtB (RND type) 0.23 OH686_08220 2-dehydropantoate 2-reductase low > 80
Pseudomonas fluorescens GW456-L13 0.62 PfGW456L13_3266 Acriflavin resistance plasma membrane protein 0.23 PfGW456L13_1839 2-dehydropantoate 2-reductase (EC 1.1.1.169) low > 87
Pseudomonas fluorescens FW300-N2E3 0.62 AO353_22895 multidrug transporter 0.22 AO353_03645 2-dehydropantoate 2-reductase low > 101
Pseudomonas fluorescens SBW25-INTG 0.61 PFLU_RS13430 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.22 PFLU_RS24155 putative 2-dehydropantoate 2-reductase low > 109
Pseudomonas fluorescens SBW25 0.61 PFLU_RS13430 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.22 PFLU_RS24155 putative 2-dehydropantoate 2-reductase low > 109
Pseudomonas simiae WCS417 0.61 PS417_12745 multidrug transporter 0.22 PS417_22515 2-dehydropantoate 2-reductase low > 88
Pseudomonas fluorescens FW300-N1B4 0.61 Pf1N1B4_4665 Acriflavin resistance plasma membrane protein 0.22 Pf1N1B4_651 2-dehydropantoate 2-reductase (EC 1.1.1.169) low > 87
Paraburkholderia sabiae LMG 24235 0.60 QEN71_RS23305 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.14 QEN71_RS38425 ketopantoate reductase family protein low > 153
Acidovorax sp. GW101-3H11 0.59 Ac3H11_3618 Cobalt-zinc-cadmium resistance protein CzcA; Cation efflux system protein CusA 0.12 Ac3H11_2346 2-dehydropantoate 2-reductase (EC 1.1.1.169) low > 79
Paraburkholderia bryophila 376MFSha3.1 0.59 H281DRAFT_06492 multidrug efflux pump 0.11 H281DRAFT_01683 ketopantoate reductase (EC 1.1.1.169) low > 103
Pseudomonas syringae pv. syringae B728a ΔmexB 0.59 Psyr_2483 Acriflavin resistance protein 0.20 Psyr_4088 ketopantoate reductase low > 86
Pseudomonas syringae pv. syringae B728a 0.59 Psyr_2483 Acriflavin resistance protein 0.20 Psyr_4088 ketopantoate reductase low > 86
Pseudomonas stutzeri RCH2 0.59 Psest_2139 Cation/multidrug efflux pump 0.24 Psest_1140 2-dehydropantoate 2-reductase low > 67
Burkholderia phytofirmans PsJN 0.58 BPHYT_RS07785 multidrug transporter 0.12 BPHYT_RS27355 2-dehydropantoate 2-reductase low > 109
Paraburkholderia graminis OAS925 0.58 ABIE53_001783 multidrug efflux pump 0.10 ABIE53_004184 2-dehydropantoate 2-reductase low > 113
Variovorax sp. SCN45 0.56 GFF6659 Multidrug efflux system MdtABC-TolC, inner-membrane proton/drug antiporter MdtB (RND type) 0.14 GFF3590 2-dehydropantoate 2-reductase (EC 1.1.1.169) low > 127
Variovorax sp. OAS795 0.54 ABID97_RS20855 efflux RND transporter permease subunit 0.14 ABID97_RS00870 2-dehydropantoate 2-reductase low > 91
Rhodanobacter denitrificans MT42 0.50 LRK55_RS09505 efflux RND transporter permease subunit 0.09 LRK55_RS02820 2-dehydropantoate 2-reductase low > 63
Rhodanobacter denitrificans FW104-10B01 0.50 LRK54_RS09845 efflux RND transporter permease subunit 0.09 LRK54_RS03070 2-dehydropantoate 2-reductase low > 59
Rhodanobacter sp. FW510-T8 0.49 OKGIIK_16105 acrB Multidrug efflux pump subunit AcrB 0.09 OKGIIK_09940 panE 2-dehydropantoate 2-reductase low > 52
Rhodopseudomonas palustris CGA009 0.49 TX73_013310 efflux RND transporter permease subunit 0.14 TX73_023700 2-dehydropantoate 2-reductase low > 86

Not shown: 10 genomes with orthologs for BNILDI_14455 only; 10 genomes with orthologs for BNILDI_22760 only