| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_2322 | | Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains | strong | 100 | 100 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_12075 | | PAS domain S-box protein | strong | 35 | 96 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS31460 | | response regulator | insig. | 32 | 87 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS09315 | | PAS domain S-box protein | cofit | 27 | 90 |
| | Azospirillum sp. SherDot2 | MPMX19_02735 | | Sensor histidine kinase RcsC | insig. | 30 | 86 |
| | Caulobacter crescentus NA1000 | CCNA_00969 | | two component sensor histidine kinase | cofit | 38 | 51 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_00969 | | two component sensor histidine kinase | cofit | 38 | 51 |
| | Shewanella loihica PV-4 | Shew_3200 | | multi-sensor hybrid histidine kinase (RefSeq) | insig. | 33 | 94 |
| | Azospirillum sp. SherDot2 | MPMX19_01260 | | Sensor histidine kinase RcsC | insig. | 28 | 79 |
| | Pseudomonas sp. S08-1 | OH686_07460 | | hypothetical protein | insig. | 27 | 97 |
| | Shewanella amazonensis SB2B | Sama_2952 | | sensory box histidine kinase/response regulator (RefSeq) | strong | 32 | 87 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS20970 | | PAS domain S-box protein | cofit | 28 | 86 |
| | Alteromonas macleodii MIT1002 | MIT1002_02963 | | Signal transduction histidine-protein kinase BarA | strong | 29 | 99 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS02280 | | hybrid sensor histidine kinase/response regulator | cofit | 27 | 96 |
| | Pseudomonas aeruginosa PA14 | IKLFDK_21180 | | hybrid sensor histidine kinase/response regulator | insig. | 29 | 85 |
| | Shewanella sp. ANA-3 | Shewana3_2015 | | putative PAS/PAC sensor protein (RefSeq) | insig. | 31 | 89 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS34720 | | hypothetical protein | insig. | 27 | 88 |
| | Caulobacter crescentus NA1000 | CCNA_03265 | | CBS pair-family sensor histidine kinase/receiver domain protein | cofit | 45 | 43 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_03265 | | CBS pair-family sensor histidine kinase/receiver domain protein | cofit | 45 | 43 |
| | Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS08705 | | response regulator | cofit | 37 | 54 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS14750 | | PAS domain S-box protein | insig. | 42 | 45 |
| | Alteromonas macleodii MIT1002 | MIT1002_03194 | | Signal transduction histidine-protein kinase BarA | insig. | 37 | 47 |
| | Shewanella oneidensis MR-1 | SO0859 | | sensory box histidine kinase/response regulator (NCBI ptt file) | insig. | 28 | 98 |
| | Dechlorosoma suillum PS | Dsui_2240 | | PAS domain S-box | cofit | 41 | 44 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS18540 | | response regulator | insig. | 41 | 46 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS08635 | | response regulator | sig. | 27 | 96 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_12415 | | two-component sensor histidine kinase BarA | insig. | 29 | 97 |
| | Dechlorosoma suillum PS | Dsui_0921 | | PAS domain S-box | cofit | 41 | 44 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_2693 | | histidine kinase (RefSeq) | strong | 35 | 48 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_1096 | | multi-sensor hybrid histidine kinase (RefSeq) | insig. | 26 | 85 |
| | Shewanella oneidensis MR-1 | SO4002 | | sensory transduction histidine kinase (NCBI ptt file) | strong | 29 | 98 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS09190 | | response regulator | insig. | 28 | 91 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_3643 | | Sensory box histidine kinase/response regulator | insig. | 39 | 45 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_2269 | | Sensory box histidine kinase/response regulator | insig. | 28 | 81 |
| | Rhodospirillum rubrum S1H | Rru_A2361 | | Multi-sensor Hybrid Histidine Kinase (NCBI) | insig. | 26 | 88 |
| | Pseudomonas simiae WCS417 | PS417_11590 | | ATPase | insig. | 39 | 48 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS23595 | | hypothetical protein | cofit | 26 | 85 |
| | Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS11100 | | response regulator | insig. | 41 | 44 |
| | Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS04110 | | response regulator | insig. | 40 | 42 |
| | Rhodospirillum rubrum S1H | Rru_A2108 | | Multi-sensor Hybrid Histidine Kinase (NCBI) | insig. | 28 | 80 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS03040 | | MASE1 domain-containing protein | insig. | 34 | 62 |
| | Shewanella sp. ANA-3 | Shewana3_3419 | | multi-sensor hybrid histidine kinase (RefSeq) | cofit | 29 | 88 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_2311 | | Sensory box histidine kinase/response regulator | insig. | 25 | 98 |
| | Pseudomonas segetis P6 | MPMX49_04005 | | Sensor histidine kinase RcsC | insig. | 25 | 96 |
| | Pseudomonas sp. RS175 | PFR28_03079 | | Sensor histidine kinase RcsC | strong | 37 | 48 |
| | Sinorhizobium meliloti 1021 | SM_b20357 | | histidine kinase | insig. | 41 | 46 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS04345 | | response regulator | strong | 28 | 84 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS20320 | | hybrid sensor histidine kinase/response regulator | cofit | 26 | 96 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU3058 | | sensory box histidine kinase/response regulator (TIGR) | insig. | 41 | 46 |
| | Pseudomonas aeruginosa PA14 | IKLFDK_20505 | | Histidine kinase | sig. | 36 | 48 |
| | Pseudomonas sp. S08-1 | OH686_06285 | | Two-component system sensor histidine kinase | insig. | 38 | 48 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT1264 | | two-component system sensor histidine kinase (NCBI ptt file) | insig. | 36 | 47 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS00275 | | response regulator | sig. | 26 | 97 |
| | Shewanella sp. ANA-3 | Shewana3_0480 | | putative PAS/PAC sensor protein (RefSeq) | cofit | 29 | 96 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_2021 | | Response regulator receiver:ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidine kinase A, N-terminal | sig. | 40 | 47 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_2021 | | Response regulator receiver:ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidine kinase A, N-terminal | insig. | 40 | 47 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_01750 | | histidine kinase | insig. | 39 | 44 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS14185 | | PAS domain S-box protein | insig. | 33 | 57 |
| | Shewanella sp. ANA-3 | Shewana3_0576 | | multi-sensor hybrid histidine kinase (RefSeq) | strong | 38 | 47 |
| | Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS06795 | | response regulator | insig. | 39 | 47 |
| | Pectobacterium carotovorum WPP14 | HER17_RS04105 | | two-component sensor histidine kinase BarA | strong | 28 | 98 |
| | Phocaeicola dorei CL03T12C01 | ABI39_RS20590 | | response regulator | insig. | 38 | 48 |
| | Caulobacter crescentus NA1000 | CCNA_02587 | | PAS-family sensor histidine kinase | cofit | 37 | 46 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_02587 | | PAS-family sensor histidine kinase | cofit | 37 | 46 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS18615 | | hypothetical protein | insig. | 35 | 47 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS34705 | | hypothetical protein | insig. | 39 | 44 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_07245 | | hybrid sensor histidine kinase/response regulator | cofit | 36 | 48 |
| | Bacteroides stercoris CC31F | HMPREF1181_RS15020 | | response regulator | insig. | 36 | 47 |
| | Bosea sp. OAE506 | ABIE41_RS11540 | | ATP-binding protein | insig. | 27 | 81 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU1563 | | sensory box histidine kinase/response regulator (TIGR) | insig. | 34 | 50 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU3269 | | sensory box histidine kinase/response regulator (TIGR) | insig. | 35 | 46 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS17385 | | PAS domain S-box protein | insig. | 26 | 84 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_182 | | Two-component hybrid sensor and regulator | insig. | 39 | 46 |
| | Azospirillum sp. SherDot2 | MPMX19_05607 | | Sensor histidine kinase RcsC | insig. | 29 | 84 |
| | Shewanella loihica PV-4 | Shew_0980 | | multi-sensor hybrid histidine kinase (RefSeq) | insig. | 29 | 95 |
| | Caulobacter crescentus NA1000 | CCNA_00689 | | PAS-family hybrid histidine kinase/receiver protein | cofit | 38 | 45 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_00689 | | PAS-family hybrid histidine kinase/receiver protein | cofit | 38 | 45 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS13280 | | hybrid sensor histidine kinase/response regulator | insig. | 31 | 86 |
| | Kangiella aquimarina DSM 16071 | B158DRAFT_2272 | | Signal transduction histidine kinase | strong | 28 | 93 |
| | Alteromonas macleodii MIT1002 | MIT1002_03602 | | Autoinducer 2 sensor kinase/phosphatase LuxQ | insig. | 39 | 48 |
| | Dechlorosoma suillum PS | Dsui_1009 | | PAS domain S-box | insig. | 38 | 45 |
| | Alteromonas macleodii MIT1002 | MIT1002_02450 | | Signal transduction histidine-protein kinase BarA | insig. | 36 | 47 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT0818 | | two-component system sensor histidine kinase (NCBI ptt file) | insig. | 38 | 45 |
| | Pseudomonas sp. S08-1 | OH686_09180 | | Two-component system sensor histidine kinase | strong | 38 | 43 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS15175 | | response regulator | insig. | 38 | 48 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_03846 | | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein | strong | 36 | 47 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_01926 | | Signal transduction histidine-protein kinase BarA | cofit | 39 | 44 |
| | Caulobacter crescentus NA1000 | CCNA_03200 | | hybrid sensor histidine kinase/receiver domain protein | cofit | 37 | 50 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_03200 | | hybrid sensor histidine kinase/receiver domain protein | cofit | 37 | 50 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_2324 | | PAS/PAC sensor hybrid histidine kinase (RefSeq) | cofit | 34 | 44 |
| | Pseudomonas fluorescens GW456-L13 | PfGW456L13_2042 | | Sensor histidine kinase/response regulator | insig. | 38 | 44 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS05670 | | response regulator | insig. | 37 | 47 |
| | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_3514 | | Sensor histidine kinase/response regulator | cofit | 37 | 44 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_05339 | | PAS domain S-box protein | insig. | 39 | 47 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_4352 | | Response regulator | insig. | 36 | 47 |
| | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.639.1 | | FIG037127: Two-component system sensor protein | insig. | 26 | 84 |
| | Pseudomonas sp. DMC3 | GFF4812 | | Sensor histidine kinase RcsC | cofit | 37 | 44 |
| | Agrobacterium fabrum C58 | Atu2332 | | two component sensor kinase/response regulator hybrid | insig. | 34 | 48 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_06800 | | hybrid sensor histidine kinase/response regulator | insig. | 28 | 86 |
| | Shewanella sp. ANA-3 | Shewana3_4016 | | putative PAS/PAC sensor protein (RefSeq) | insig. | 27 | 85 |