| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Dechlorosoma suillum PS | Dsui_3333 | | response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains | insig. | 100 | 100 |
| | Dechlorosoma suillum PS | Dsui_3335 | | response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains | cofit | 60 | 96 |
| | Pseudomonas sp. S08-1 | OH686_08940 | | diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) | insig. | 39 | 42 |
| | Dechlorosoma suillum PS | Dsui_1890 | | diguanylate cyclase (GGDEF) domain-containing protein | insig. | 40 | 42 |
| | Dechlorosoma suillum PS | Dsui_1885 | | response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains | insig. | 44 | 46 |
| | Dechlorosoma suillum PS | Dsui_2046 | | PAS domain S-box/diguanylate cyclase (GGDEF) domain-containing protein | cofit | 38 | 36 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_3165 | | diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) | insig. | 39 | 40 |
| | Pseudomonas simiae WCS417 | PS417_05440 | | chemotaxis protein CheY | insig. | 39 | 36 |
| | Pseudomonas sp. S08-1 | OH686_08945 | | hypothetical protein | cofit | 37 | 46 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_16190 | | chemotaxis protein CheY | insig. | 37 | 41 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS05525 | | response regulator | insig. | 38 | 41 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS05525 | | response regulator | insig. | 38 | 41 |
| | Dechlorosoma suillum PS | Dsui_3335 | | response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains | cofit | 39 | 30 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_02781 | | Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains | insig. | 37 | 33 |
| | Pseudomonas putida KT2440 | PP_2942 | | Response regulator | insig. | 36 | 42 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_01276 | | Regulator of RpoS | cofit | 39 | 36 |
| | Paraburkholderia graminis OAS925 | ABIE53_006006 | | adenylate cyclase | sig. | 34 | 40 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_05530 | | two-component system response regulator | cofit | 34 | 45 |
| | Dechlorosoma suillum PS | Dsui_1886 | | response regulator containing a CheY-like receiver domain and an HD-GYP domain | cofit | 36 | 47 |
| | Dickeya dianthicola ME23 | DZA65_RS10630 | | response regulator | insig. | 38 | 43 |
| | Dickeya dianthicola 67-19 | HGI48_RS10210 | | response regulator | insig. | 38 | 43 |
| | Pseudomonas sp. SVBP6 | COO64_RS20885 | | HD domain-containing phosphohydrolase | insig. | 36 | 47 |
| | Dickeya dadantii 3937 | DDA3937_RS10180 | | response regulator | insig. | 36 | 43 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_05525 | | transcriptional regulator | insig. | 39 | 36 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_5467 | | Response regulator | sig. | 32 | 47 |
| | Pseudomonas orientalis W4I3 | QF045_RS08375 | | response regulator | insig. | 35 | 39 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_2271 | | His Kinase A (phosphoacceptor) domain./Response regulator receiver domain./Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | strong | 33 | 36 |
| | Pseudomonas sp. S08-1 | OH686_08910 | | Phytochrome-like protein / Cph2 | cofit | 36 | 36 |
| | Pseudomonas sp. S08-1 | OH686_08940 | | diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) | insig. | 35 | 36 |
| | Shewanella oneidensis MR-1 | SO2541 | | response regulator (NCBI ptt file) | insig. | 33 | 43 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_17715 | | chemotaxis protein CheY | insig. | 32 | 46 |
| | Pseudomonas sp. S08-1 | OH686_08925 | | Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB | cofit | 31 | 48 |
| | Dechlorosoma suillum PS | Dsui_3334 | | PAS domain S-box/diguanylate cyclase (GGDEF) domain-containing protein | cofit | 36 | 33 |
| | Ralstonia sp. UNC404CL21Col | ABZR87_RS16850 | | HD domain-containing phosphohydrolase | insig. | 36 | 42 |
| | Ralstonia solanacearum PSI07 | RPSI07_RS05625 | | two-component system response regulator | insig. | 36 | 43 |
| | Paraburkholderia graminis OAS925 | ABIE53_006006 | | adenylate cyclase | sig. | 33 | 50 |
| | Marinobacter adhaerens HP15 | HP15_3664 | | response regulator receiver modulated metal dependent phosphohydrolase | cofit | 34 | 41 |
| | Pseudomonas sp. RS175 | PFR28_03482 | | Sensor histidine kinase RcsC | cofit | 32 | 46 |
| | Pseudomonas sp. BP01 | JOY50_RS14530 | | sigma-54 dependent transcriptional regulator | insig. | 38 | 41 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS14880 | | response regulator receiver modulated metal-depenent phosphohydrolase | cofit | 35 | 40 |
| | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_788 | | Response regulator | insig. | 35 | 40 |
| | Pseudomonas aeruginosa MRSN321 | DY961_RS02585 | | response regulator | insig. | 26 | 85 |
| | Pseudomonas aeruginosa PA14 | IKLFDK_14640 | | two-component system response regulator | insig. | 26 | 85 |
| | Pseudomonas aeruginosa PUPa3 | DQ20_RS33010 | | response regulator | insig. | 26 | 85 |
| | Alteromonas macleodii MIT1002 | MIT1002_03637 | | Hydrogenase transcriptional regulatory protein hupR1 | insig. | 33 | 47 |
| | Rhodospirillum rubrum S1H | Rru_A0692 | | Response regulator receiver domain protein (CheY) (NCBI) | insig. | 32 | 40 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_3168 | | Response regulator | insig. | 34 | 46 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS14555 | | response regulator | strong | 29 | 42 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF2210 | | Hydrogenase transcriptional regulatory protein HoxA | insig. | 38 | 34 |
| | Variovorax sp. OAS795 | ABID97_RS13590 | | sigma-54 dependent transcriptional regulator | insig. | 36 | 35 |
| | Sinorhizobium meliloti 1021 | SM_b21200 | | two-component response regulator protein | insig. | 36 | 44 |
| | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.2768.1 | | hypothetical protein | strong | 35 | 41 |
| | Pseudomonas putida KT2440 | PP_1401 | | C4-dicarboxylate transport transcriptional regulatory protein | strong | 35 | 46 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_02781 | | Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains | insig. | 31 | 50 |
| | Shewanella oneidensis MR-1 | SO2539 | | response regulator (NCBI ptt file) | insig. | 33 | 39 |
| | Rhodospirillum rubrum S1H | Rru_A0691 | | Predicted signal transduction protein (NCBI) | insig. | 34 | 44 |
| | Pseudomonas stutzeri RCH2 | Psest_4132 | | alpha-ketoglutarate DNA-binding response regulator (mifR) (from data) | strong | 34 | 46 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_14720 | | sigma-54-dependent Fis family transcriptional regulator | insig. | 34 | 47 |
| | Pseudomonas sp. S08-1 | OH686_00995 | | diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) | insig. | 36 | 41 |
| | Pseudomonas sp. S08-1 | OH686_08945 | | hypothetical protein | cofit | 33 | 45 |
| | Lysobacter sp. OAE881 | ABIE51_RS16595 | | EAL domain-containing protein | cofit | 34 | 33 |
| | Rhizobium sp. OAE497 | ABIE40_RS26335 | | sigma-54 dependent transcriptional regulator | strong | 29 | 58 |
| | Pseudomonas aeruginosa PA14 | IKLFDK_25855 | | DNA-binding response regulator | sig. | 36 | 41 |
| | Dechlorosoma suillum PS | Dsui_1890 | | diguanylate cyclase (GGDEF) domain-containing protein | insig. | 32 | 46 |
| | Pseudomonas segetis P6 | ACVTMO_RS01055 | | sigma-54-dependent transcriptional regulator | insig. | 33 | 47 |
| | Pseudomonas sp. SVBP6 | COO64_RS20885 | | HD domain-containing phosphohydrolase | insig. | 34 | 45 |
| | Pseudomonas sp. RS175 | PFR28_03462 | | C4-dicarboxylate transport transcriptional regulatory protein DctD | strong | 34 | 42 |
| | Pseudomonas aeruginosa MRSN321 | DY961_RS25855 | | sigma-54 dependent transcriptional regulator | strong | 35 | 41 |
| | Pseudomonas aeruginosa PUPa3 | DQ20_RS58285 | | sigma-54 dependent transcriptional regulator | strong | 35 | 41 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS05335 | | response regulator | cofit | 31 | 53 |
| | Pseudomonas segetis P6 | ACVTMO_RS10700 | | response regulator | insig. | 25 | 84 |
| | Sinorhizobium meliloti 1021 | SM_b20613 | | C4-dicarboxylate transport transcriptional regulator | strong | 33 | 44 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU3215 | drrA | response regulator (TIGR) | insig. | 37 | 36 |
| | Pseudomonas sp. S08-1 | OH686_08910 | | Phytochrome-like protein / Cph2 | cofit | 33 | 47 |
| | Pseudomonas sp. SVBP6 | COO64_RS26185 | | sigma-54 dependent transcriptional regulator | insig. | 35 | 41 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS09930 | | hybrid sensor histidine kinase/response regulator | cofit | 34 | 43 |
| | Dechlorosoma suillum PS | Dsui_2046 | | PAS domain S-box/diguanylate cyclase (GGDEF) domain-containing protein | cofit | 33 | 46 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS05355 | | response regulator receiver modulated metal-depenent phosphohydrolase | insig. | 32 | 44 |
| | Pseudomonas sp. DMC3 | GFF5041 | | C4-dicarboxylate transport transcriptional regulatory protein DctD | cofit | 35 | 41 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS14875 | | response regulator | insig. | 35 | 39 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS11550 | | sigma-54-dependent Fis family transcriptional regulator | insig. | 34 | 39 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS05355 | | response regulator receiver modulated metal-depenent phosphohydrolase | insig. | 31 | 41 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_17800 | | C4-dicarboxylate ABC transporter | strong | 35 | 41 |
| | Dechlorosoma suillum PS | Dsui_3334 | | PAS domain S-box/diguanylate cyclase (GGDEF) domain-containing protein | cofit | 30 | 49 |
| | Dechlorosoma suillum PS | Dsui_1154 | | response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains | insig. | 32 | 40 |
| | Ralstonia sp. UNC404CL21Col | ABZR87_RS16850 | | HD domain-containing phosphohydrolase | insig. | 31 | 48 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS18645 | | chemotaxis protein CheY | insig. | 30 | 42 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS08380 | | sigma-54-dependent Fis family transcriptional regulator | insig. | 36 | 40 |
| | Pseudomonas fluorescens GW456-L13 | PfGW456L13_1806 | | Nitrogen regulation protein NR(I) | strong | 35 | 41 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_5487 | | Nitrogen regulation protein NR(I) | strong | 35 | 41 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS05525 | | response regulator | insig. | 31 | 48 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS05525 | | response regulator | insig. | 31 | 48 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_01292 | | Regulatory protein AtoC | cofit | 31 | 58 |
| | Cellulophaga baltica 18 | M666_RS19210 | | sigma-54 dependent transcriptional regulator | insig. | 28 | 45 |
| | Marinobacter adhaerens HP15 | HP15_3664 | | response regulator receiver modulated metal dependent phosphohydrolase | cofit | 30 | 48 |
| | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_685 | | Nitrogen regulation protein NR(I) | no data | 35 | 41 |
| | Dickeya dianthicola 67-19 | HGI48_RS10215 | | HDOD domain-containing protein | insig. | 36 | 36 |
| | Agrobacterium fabrum C58 | Atu3296 | | two component response regulator for C4-dicarboxylate transport | strong | 34 | 49 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_3995 | | Helix-turn-helix, Fis-type | sig. | 35 | 41 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_3995 | | Helix-turn-helix, Fis-type | insig. | 35 | 41 |