Conservation of cofitness between JDDGAC_28305 and JDDGAC_10650 in Escherichia coli ECRC98

56 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli ECRC98 1.0 JDDGAC_28305 mdtB multidrug efflux RND transporter permease subunit MdtB 1.0 JDDGAC_10650 pxpA 5-oxoprolinase subunit PxpA 0.76 4
Escherichia coli ECRC102 1.00 NIAGMN_22140 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 NIAGMN_05050 pxpA 5-oxoprolinase subunit PxpA — —
Escherichia coli ECRC100 1.00 OKFHMN_24195 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 OKFHMN_06995 pxpA 5-oxoprolinase subunit PxpA low > 80
Escherichia coli ECRC99 1.00 KEDOAH_03955 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 KEDOAH_20970 pxpA 5-oxoprolinase subunit PxpA — —
Escherichia coli ECRC101 1.00 MCAODC_20745 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 MCAODC_26215 pxpA 5-oxoprolinase subunit PxpA low > 87
Escherichia coli ECOR27 1.00 NOLOHH_15540 mdtB multidrug efflux RND transporter permease subunit MdtB 0.97 NOLOHH_23380 pxpA 5-oxoprolinase subunit PxpA low > 75
Escherichia coli BW25113 1.00 b2075 mdtB multidrug efflux system, subunit B (NCBI) 0.97 b0713 ybgL hypothetical protein (NCBI) low > 76
Escherichia coli Nissle 1917 1.00 ECOLIN_RS12200 multidrug efflux RND transporter permease subunit MdtB 0.95 ECOLIN_RS03815 5-oxoprolinase subunit PxpA low > 55
Escherichia fergusonii Becca 1.00 EFB2_01780 Multidrug resistance protein MdtB 0.95 EFB2_03390 5-oxoprolinase subunit A low > 86
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_01629 Multidrug resistance protein MdtB 0.97 OHPLBJKB_03004 hypothetical protein low > 73
Escherichia coli ECRC62 1.00 BNILDI_14455 mdtB multidrug efflux RND transporter permease subunit MdtB 0.97 BNILDI_21375 pxpA 5-oxoprolinase subunit PxpA low > 75
Escherichia coli ECOR38 1.00 HEPCGN_02885 mdtB multidrug efflux RND transporter permease subunit MdtB 0.94 HEPCGN_01215 pxpA 5-oxoprolinase subunit PxpA 0.59 22
Escherichia coli BL21 1.00 ECD_01980 multidrug efflux system, subunit B 0.97 ECD_00673 UPF0271 family protein low > 61
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.91 GFF3854 Multidrug transporter MdtB 0.82 GFF4618 Lactam utilization protein LamB low > 78
Klebsiella michiganensis M5al 0.91 BWI76_RS19255 multidrug transporter subunit MdtB 0.81 BWI76_RS08360 LamB/YcsF family protein low > 92
Enterobacter sp. TBS_079 0.90 MPMX20_03061 Multidrug resistance protein MdtB 0.77 MPMX20_01347 5-oxoprolinase subunit A low > 85
Enterobacter asburiae PDN3 0.90 EX28DRAFT_0483 Cation/multidrug efflux pump 0.78 EX28DRAFT_2274 Uncharacterized proteins, homologs of lactam utilization protein B low > 76
Serratia liquefaciens MT49 0.81 IAI46_18975 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.74 IAI46_06225 5-oxoprolinase subunit PxpA low > 86
Pantoea sp. MT58 0.81 IAI47_06870 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.69 IAI47_13795 5-oxoprolinase subunit PxpA low > 76
Pectobacterium carotovorum WPP14 0.79 HER17_RS06320 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.68 HER17_RS14975 5-oxoprolinase subunit PxpA low > 75
Dickeya dadantii 3937 0.77 DDA3937_RS15265 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.66 DDA3937_RS06425 5-oxoprolinase subunit PxpA low > 74
Dickeya dianthicola ME23 0.77 DZA65_RS16165 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.65 DZA65_RS06815 5-oxoprolinase subunit PxpA low > 75
Dickeya dianthicola 67-19 0.76 HGI48_RS15345 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.64 HGI48_RS06470 5-oxoprolinase subunit PxpA low > 71
Herbaspirillum seropedicae SmR1 0.68 HSERO_RS07650 multidrug transporter 0.63 HSERO_RS08780 LamB/YcsF family protein — —
Ralstonia solanacearum UW163 0.66 UW163_RS21010 multidrug transporter subunit MdtB 0.64 UW163_RS10245 LamB/YcsF family protein — —
Ralstonia solanacearum IBSBF1503 0.66 RALBFv3_RS18120 multidrug transporter subunit MdtB 0.64 RALBFv3_RS03425 LamB/YcsF family protein — —
Ralstonia solanacearum PSI07 0.65 RPSI07_RS05515 multidrug transporter subunit MdtB 0.63 RPSI07_RS13790 LamB/YcsF family protein low > 81
Ralstonia sp. UNC404CL21Col 0.65 ABZR87_RS19025 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.63 ABZR87_RS15325 5-oxoprolinase subunit PxpA 0.65 17
Ralstonia solanacearum GMI1000 0.65 RS_RS22915 multidrug transporter subunit MdtB 0.63 RS_RS10885 LamB/YcsF family protein low > 80
Cupriavidus basilensis FW507-4G11 0.64 RR42_RS03310 multidrug transporter 0.63 RR42_RS00650 hypothetical protein low > 128
Pseudomonas sp. RS175 0.63 PFR28_02194 Multidrug resistance protein MdtB 0.31 PFR28_00728 5-oxoprolinase subunit A 3 low > 88
Pseudomonas fluorescens FW300-N2C3 0.62 AO356_25875 multidrug transporter 0.32 AO356_04335 hypothetical protein low > 104
Rahnella sp. WP5 0.62 EX31_RS13380 MMPL family transporter 0.73 EX31_RS23395 5-oxoprolinase subunit PxpA low > 89
Pseudomonas putida KT2440 0.62 PP_3584 multidrug efflux transport system - membrane subunit 0.31 PP_2920 putative nitrogen-containing compound degradation enzyme low > 96
Pseudomonas fluorescens FW300-N2E2 0.62 Pf6N2E2_1272 Acriflavin resistance plasma membrane protein 0.31 Pf6N2E2_2708 Lactam utilization protein LamB low > 103
Pseudomonas sp. S08-1 0.62 OH686_00925 Multidrug efflux system MdtABC-TolC, inner-membrane proton/drug antiporter MdtB (RND type) 0.33 OH686_08750 Lactam utilization protein LamB low > 80
Pseudomonas fluorescens GW456-L13 0.62 PfGW456L13_3266 Acriflavin resistance plasma membrane protein 0.32 PfGW456L13_4478 Lactam utilization protein LamB low > 87
Pseudomonas fluorescens FW300-N2E3 0.62 AO353_22895 multidrug transporter 0.31 AO353_17995 hypothetical protein low > 101
Pseudomonas fluorescens SBW25 0.61 PFLU_RS13430 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.35 PFLU_RS23510 5-oxoprolinase subunit PxpA low > 109
Pseudomonas fluorescens SBW25-INTG 0.61 PFLU_RS13430 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.35 PFLU_RS23510 5-oxoprolinase subunit PxpA low > 109
Pseudomonas fluorescens FW300-N1B4 0.61 Pf1N1B4_4665 Acriflavin resistance plasma membrane protein 0.32 Pf1N1B4_3366 Lactam utilization protein LamB low > 87
Pseudomonas simiae WCS417 0.61 PS417_12745 multidrug transporter 0.34 PS417_21910 LamB/YcsF family protein low > 88
Paraburkholderia sabiae LMG 24235 0.60 QEN71_RS23305 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.62 QEN71_RS28660 5-oxoprolinase subunit PxpA low > 153
Paraburkholderia bryophila 376MFSha3.1 0.59 H281DRAFT_06492 multidrug efflux pump 0.63 H281DRAFT_05811 UPF0271 protein low > 103
Pseudomonas syringae pv. syringae B728a ΔmexB 0.59 Psyr_2483 Acriflavin resistance protein 0.37 Psyr_0497 LamB/YcsF low > 86
Pseudomonas syringae pv. syringae B728a 0.59 Psyr_2483 Acriflavin resistance protein 0.37 Psyr_0497 LamB/YcsF low > 86
Pseudomonas stutzeri RCH2 0.59 Psest_2139 Cation/multidrug efflux pump 0.32 Psest_1542 Uncharacterized proteins, homologs of lactam utilization protein B low > 67
Burkholderia phytofirmans PsJN 0.58 BPHYT_RS07785 multidrug transporter 0.62 BPHYT_RS18635 LamB/YcsF family protein low > 109
Paraburkholderia graminis OAS925 0.58 ABIE53_001783 multidrug efflux pump 0.62 ABIE53_000049 UPF0271 protein low > 113
Castellaniella sp019104865 MT123 0.57 ABCV34_RS14620 multidrug efflux RND transporter permease subunit 0.35 ABCV34_RS01510 5-oxoprolinase subunit PxpA low > 48
Variovorax sp. SCN45 0.56 GFF6659 Multidrug efflux system MdtABC-TolC, inner-membrane proton/drug antiporter MdtB (RND type) 0.65 GFF2324 Lactam utilization protein LamB 0.41 62
Variovorax sp. OAS795 0.54 ABID97_RS20855 efflux RND transporter permease subunit 0.65 ABID97_RS23840 5-oxoprolinase subunit PxpA low > 91
Azospirillum sp. SherDot2 0.53 MPMX19_05477 Multidrug resistance protein MdtB 0.38 MPMX19_04959 5-oxoprolinase subunit A low > 112
Magnetospirillum magneticum AMB-1 0.52 AMB_RS17370 acriflavine resistance protein B 0.46 AMB_RS15095 LamB/YcsF family protein low > 64
Rhodanobacter sp. FW510-T8 0.49 OKGIIK_16105 acrB Multidrug efflux pump subunit AcrB 0.48 OKGIIK_04730 5-oxoprolinase subunit A low > 52
Rhodopseudomonas palustris CGA009 0.49 TX73_013310 efflux RND transporter permease subunit 0.40 TX73_013895 LamB/YcsF family protein low > 86
Phaeobacter inhibens DSM 17395 0.13 PGA1_78p00510 multidrug transporter MdtB 0.37 PGA1_c28700 LamB/YcsF family protein low > 62

Not shown: 9 genomes with orthologs for JDDGAC_28305 only; 17 genomes with orthologs for JDDGAC_10650 only