Conservation of cofitness between HER17_RS19155 and HER17_RS01110 in Pectobacterium carotovorum WPP14

50 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pectobacterium carotovorum WPP14 1.0 HER17_RS19155 NADP-dependent oxidoreductase 1.0 HER17_RS01110 trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase 0.59 16
Pseudomonas putida KT2440 0.79 PP_2476 NADPH-dependent curcumin/dihydrocurcumin reductase 0.71 PP_4947 proline dehydrogenase/1-pyrroline-5-carboxylate dehydrogenase low > 96
Enterobacter sp. TBS_079 0.79 MPMX20_02410 NADPH-dependent curcumin reductase 0.73 MPMX20_01702 Bifunctional protein PutA low > 85
Enterobacter asburiae PDN3 0.78 EX28DRAFT_1041 Putative NADP-dependent oxidoreductases 0.73 EX28DRAFT_1911 L-proline dehydrogenase (EC 1.5.99.8)/delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) low > 76
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.76 GFF2580 Putative oxidoreductase YncB 0.72 GFF3301 Transcriptional repressor of PutA and PutP / Proline dehydrogenase (EC 1.5.99.8) (Proline oxidase) / Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.2.1.88) low > 78
Escherichia coli ECRC99 0.76 KEDOAH_26910 curA NADPH-dependent curcumin/dihydrocurcumin reductase 0.73 KEDOAH_23140 putA trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase — —
Escherichia coli ECRC101 0.76 MCAODC_16410 curA NADPH-dependent curcumin/dihydrocurcumin reductase 0.73 MCAODC_23990 putA trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase low > 87
Escherichia coli ECRC98 0.76 JDDGAC_04020 curA NADPH-dependent curcumin/dihydrocurcumin reductase 0.73 JDDGAC_08215 putA trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase low > 86
Escherichia coli HS(pFamp)R (ATCC 700891) 0.76 OHPLBJKB_02264 NADPH-dependent curcumin reductase 0.73 OHPLBJKB_02652 Bifunctional protein PutA low > 73
Escherichia coli BW25113 0.76 b1449 yncB predicted oxidoreductase, Zn-dependent and NAD(P)-binding (RefSeq) 0.73 b1014 putA fused DNA-binding transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase (NCBI) low > 76
Escherichia coli ECRC102 0.76 NIAGMN_25665 curA NADPH-dependent curcumin/dihydrocurcumin reductase 0.73 NIAGMN_23730 putA trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase — —
Escherichia coli ECRC100 0.76 OKFHMN_01530 curA NADPH-dependent curcumin/dihydrocurcumin reductase 0.73 OKFHMN_04605 putA trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase low > 80
Escherichia coli ECOR38 0.76 HEPCGN_26280 curA NADPH-dependent curcumin/dihydrocurcumin reductase 0.73 HEPCGN_23535 putA trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase low > 87
Escherichia coli BL21 0.76 ECD_01406 curcumin/dihydrocurcumin reductase, NADPH-dependent 0.73 ECD_01017 fused DNA-binding transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase — —
Escherichia coli ECOR27 0.76 NOLOHH_19200 curA NADPH-dependent curcumin/dihydrocurcumin reductase 0.73 NOLOHH_21505 putA trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase low > 75
Klebsiella michiganensis M5al 0.75 BWI76_RS13485 NADP-dependent oxidoreductase 0.72 BWI76_RS10795 L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88); Proline dehydrogenase (EC 1.5.5.2) (from data) low > 92
Serratia liquefaciens MT49 0.74 IAI46_16075 NADP-dependent oxidoreductase 0.78 IAI46_15745 trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase low > 86
Rahnella sp. WP5 0.72 EX31_RS23665 NADP-dependent oxidoreductase 0.74 EX31_RS09420 trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase low > 89
Pantoea sp. MT58 0.69 IAI47_09985 NADP-dependent oxidoreductase 0.71 IAI47_08195 trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase low > 76
Acinetobacter radioresistens SK82 0.69 MPMX26_00889 NADPH-dependent curcumin reductase 0.51 MPMX26_01466 Bifunctional protein PutA — —
Pseudomonas sp. RS175 0.68 PFR28_01076 NADPH-dependent curcumin reductase 0.71 PFR28_05053 Bifunctional protein PutA low > 88
Pseudomonas fluorescens FW300-N2C3 0.68 AO356_02500 2-alkenal reductase 0.71 AO356_09015 transcriptional regulator low > 104
Pseudomonas fluorescens FW300-N2E2 0.67 Pf6N2E2_2326 Putative oxidoreductase YncB 0.71 Pf6N2E2_3685 Transcriptional repressor of PutA and PutP / Proline dehydrogenase (EC 1.5.99.8) (Proline oxidase) / Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) low > 103
Pseudomonas fluorescens SBW25-INTG 0.67 PFLU_RS22420 NADP-dependent oxidoreductase 0.71 PFLU_RS02230 trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase low > 109
Pseudomonas fluorescens SBW25 0.67 PFLU_RS22420 NADP-dependent oxidoreductase 0.71 PFLU_RS02230 trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase low > 109
Phaeobacter inhibens DSM 17395 0.67 PGA1_c30440 putative NADP-dependent oxidoreductase 0.36 PGA1_c11750 L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88); Proline dehydrogenase (EC 1.5.5.2) (from data) low > 62
Pseudomonas fluorescens GW456-L13 0.67 PfGW456L13_4075 Putative oxidoreductase YncB 0.71 PfGW456L13_223 Transcriptional repressor of PutA and PutP / Proline dehydrogenase (EC 1.5.99.8) (Proline oxidase) / Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) low > 87
Erwinia tracheiphila SCR3 0.61 LU632_RS09100 NADP-dependent oxidoreductase 0.70 LU632_RS13740 putA trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase 0.46 64
Herbaspirillum seropedicae SmR1 0.59 HSERO_RS18900 2-alkenal reductase 0.49 HSERO_RS00905 L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88); Proline dehydrogenase (EC 1.5.5.2) (from data) low > 78
Ralstonia sp. UNC404CL21Col 0.59 ABZR87_RS06150 NADP-dependent oxidoreductase 0.64 ABZR87_RS03970 trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase low > 80
Rhodospirillum rubrum S1H 0.53 Rru_A0474 Zinc-containing alcohol dehydrogenase superfamily (NCBI) 0.35 Rru_A0656 delta-1-pyrroline-5-carboxylate dehydrogenase 3 (NCBI) low > 58
Rhizobium sp. OAE497 0.48 ABIE40_RS19855 NADP-dependent oxidoreductase 0.50 ABIE40_RS23445 trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase low > 107
Burkholderia phytofirmans PsJN 0.46 BPHYT_RS09595 2-alkenal reductase 0.62 BPHYT_RS19355 bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase low > 109
Cupriavidus basilensis FW507-4G11 0.46 RR42_RS11055 2-alkenal reductase 0.65 RR42_RS20125 L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88); Proline dehydrogenase (EC 1.5.5.2) (from data) low > 128
Paraburkholderia sabiae LMG 24235 0.46 QEN71_RS21845 NADP-dependent oxidoreductase 0.61 QEN71_RS29240 trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase low > 153
Ralstonia solanacearum PSI07 0.45 RPSI07_RS16380 NADP-dependent oxidoreductase 0.63 RPSI07_RS08540 trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase low > 81
Paraburkholderia graminis OAS925 0.45 ABIE53_002157 NADPH-dependent curcumin reductase CurA 0.58 ABIE53_000244 RHH-type proline utilization regulon transcriptional repressor/proline dehydrogenase/delta 1-pyrroline-5-carboxylate dehydrogenase low > 113
Paraburkholderia bryophila 376MFSha3.1 0.45 H281DRAFT_00922 hypothetical protein 0.62 H281DRAFT_02404 L-proline dehydrogenase /delta-1-pyrroline-5-carboxylate dehydrogenase low > 103
Ralstonia solanacearum GMI1000 0.45 RS_RS08920 NADP-dependent oxidoreductase 0.64 RS_RS16540 trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase low > 80
Ralstonia solanacearum UW163 0.45 UW163_RS14405 NADP-dependent oxidoreductase 0.63 UW163_RS04885 trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase — —
Ralstonia solanacearum IBSBF1503 0.45 RALBFv3_RS01095 NADP-dependent oxidoreductase 0.63 RALBFv3_RS08725 trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase low > 76
Acidovorax sp. GW101-3H11 0.43 Ac3H11_2516 Quinone oxidoreductase (EC 1.6.5.5) 0.59 Ac3H11_2850 L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88); Proline dehydrogenase (EC 1.5.5.2) (from data) low > 79
Variovorax sp. SCN45 0.43 GFF1350 Quinone oxidoreductase (EC 1.6.5.5) 0.57 GFF5175 Transcriptional repressor of PutA and PutP / Proline dehydrogenase (EC 1.5.5.2) / Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.2.1.88) low > 127
Pseudomonas fluorescens FW300-N2E3 0.43 AO353_01665 NADP-dependent oxidoreductase 0.71 AO353_12810 L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88); Proline dehydrogenase (EC 1.5.5.2) (from data) low > 101
Pseudomonas simiae WCS417 0.42 PS417_09060 NADP-dependent oxidoreductase 0.71 PS417_02175 transcriptional regulator low > 88
Pseudomonas syringae pv. syringae B728a ΔmexB 0.41 Psyr_1837 Zinc-containing alcohol dehydrogenase superfamily 0.69 Psyr_0506 L-proline dehydrogenase / delta-1-pyrroline-5-carboxylate dehydrogenase low > 86
Pseudomonas syringae pv. syringae B728a 0.41 Psyr_1837 Zinc-containing alcohol dehydrogenase superfamily 0.69 Psyr_0506 L-proline dehydrogenase / delta-1-pyrroline-5-carboxylate dehydrogenase low > 86
Pseudomonas fluorescens FW300-N1B4 0.41 Pf1N1B4_513 Putative NADP-dependent oxidoreductase PA1648 0.71 Pf1N1B4_1489 Transcriptional repressor of PutA and PutP / Proline dehydrogenase (EC 1.5.99.8) (Proline oxidase) / Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) low > 87
Alteromonas macleodii MIT1002 0.36 MIT1002_03891 NADPH-dependent curcumin reductase 0.38 MIT1002_00637 Bifunctional protein PutA low > 70
Dinoroseobacter shibae DFL-12 0.34 Dshi_2983 Alcohol dehydrogenase zinc-binding domain protein (RefSeq) 0.36 Dshi_2311 delta-1-pyrroline-5-carboxylate dehydrogenase (RefSeq) low > 64
Sphingomonas koreensis DSMZ 15582 0.31 Ga0059261_2876 Putative NADP-dependent oxidoreductases 0.47 Ga0059261_3926 L-proline dehydrogenase (EC 1.5.99.8)/delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) low > 68

Not shown: 18 genomes with orthologs for HER17_RS19155 only; 13 genomes with orthologs for HER17_RS01110 only