Conservation of cofitness between HEPCGN_02880 and HEPCGN_20965 in Escherichia coli ECOR38

60 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli ECOR38 1.0 HEPCGN_02880 mdtC multidrug efflux RND transporter permease subunit MdtC 1.0 HEPCGN_20965 ppk1 polyphosphate kinase 1 0.57 19
Escherichia coli ECOR27 0.99 NOLOHH_15535 mdtC multidrug efflux RND transporter permease subunit MdtC 1.00 NOLOHH_13450 ppk1 polyphosphate kinase 1 low > 75
Escherichia coli ECRC62 0.99 BNILDI_14450 mdtC multidrug efflux RND transporter permease subunit MdtC 1.00 BNILDI_12260 ppk1 polyphosphate kinase 1 low > 75
Escherichia coli BL21 0.99 ECD_01981 multidrug efflux system, subunit C 1.00 ECD_02393 polyphosphate kinase, component of RNA degradosome low > 61
Escherichia coli ECRC102 0.99 NIAGMN_22135 mdtC multidrug efflux RND transporter permease subunit MdtC 1.00 NIAGMN_19570 ppk1 polyphosphate kinase 1 — —
Escherichia coli ECRC98 0.99 JDDGAC_28300 mdtC multidrug efflux RND transporter permease subunit MdtC 1.00 JDDGAC_25745 ppk1 polyphosphate kinase 1 low > 86
Escherichia coli ECRC99 0.99 KEDOAH_03960 mdtC multidrug efflux RND transporter permease subunit MdtC 1.00 KEDOAH_06420 ppk1 polyphosphate kinase 1 — —
Escherichia coli ECRC101 0.99 MCAODC_20750 mdtC multidrug efflux RND transporter permease subunit MdtC 1.00 MCAODC_12330 ppk1 polyphosphate kinase 1 low > 87
Escherichia coli ECRC100 0.99 OKFHMN_24190 mdtC multidrug efflux RND transporter permease subunit MdtC 1.00 OKFHMN_21800 ppk1 polyphosphate kinase 1 low > 80
Escherichia coli BW25113 0.99 b2076 mdtC multidrug efflux system, subunit C (NCBI) 1.00 b2501 ppk polyphosphate kinase (NCBI) low > 76
Escherichia coli Nissle 1917 0.99 ECOLIN_RS12205 multidrug efflux RND transporter permease subunit MdtC 1.00 ECOLIN_RS14200 polyphosphate kinase 1 — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.99 OHPLBJKB_01628 Multidrug resistance protein MdtC 1.00 OHPLBJKB_01225 Polyphosphate kinase low > 73
Escherichia fergusonii Becca 0.99 EFB2_01779 Multidrug resistance protein MdtC 1.00 EFB2_01397 Polyphosphate kinase low > 86
Enterobacter asburiae PDN3 0.92 EX28DRAFT_0482 Cation/multidrug efflux pump 0.95 EX28DRAFT_0166 polyphosphate kinase 1 low > 76
Enterobacter sp. TBS_079 0.91 MPMX20_03062 Multidrug resistance protein MdtC 0.95 MPMX20_03356 Polyphosphate kinase low > 85
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.90 GFF3853 Multidrug transporter MdtC 0.94 GFF2167 Polyphosphate kinase (EC 2.7.4.1) low > 78
Klebsiella michiganensis M5al 0.90 BWI76_RS19260 multidrug transporter subunit MdtC 0.92 BWI76_RS20995 RNA degradosome polyphosphate kinase low > 92
Serratia liquefaciens MT49 0.82 IAI46_18980 multidrug efflux RND transporter permease subunit MdtC 0.86 IAI46_18915 polyphosphate kinase 1 0.45 32
Pectobacterium carotovorum WPP14 0.79 HER17_RS06315 multidrug efflux RND transporter permease subunit MdtC 0.83 HER17_RS06425 polyphosphate kinase 1 low > 75
Pantoea sp. MT58 0.79 IAI47_06865 multidrug efflux RND transporter permease subunit MdtC 0.84 IAI47_05155 polyphosphate kinase 1 low > 76
Dickeya dianthicola 67-19 0.78 HGI48_RS15350 multidrug efflux RND transporter permease subunit MdtC 0.82 HGI48_RS15225 polyphosphate kinase 1 low > 71
Dickeya dadantii 3937 0.78 DDA3937_RS15270 multidrug efflux RND transporter permease subunit MdtC 0.83 DDA3937_RS15150 polyphosphate kinase 1 low > 74
Dickeya dianthicola ME23 0.78 DZA65_RS16170 multidrug efflux RND transporter permease subunit MdtC 0.83 DZA65_RS16045 polyphosphate kinase 1 low > 75
Erwinia tracheiphila SCR3 0.73 LU632_RS08685 mdtC multidrug efflux RND transporter permease subunit MdtC 0.87 LU632_RS08260 ppk1 polyphosphate kinase 1 low > 74
Ralstonia solanacearum PSI07 0.63 RPSI07_RS05520 nodulation protein 0.27 RPSI07_RS15330 polyphosphate kinase 1 low > 81
Ralstonia solanacearum GMI1000 0.63 RS_RS22920 nodulation protein 0.27 RS_RS07705 polyphosphate kinase 1 low > 80
Ralstonia solanacearum IBSBF1503 0.63 RALBFv3_RS18115 nodulation protein 0.26 RALBFv3_RS02115 polyphosphate kinase 1 low > 76
Ralstonia solanacearum UW163 0.63 UW163_RS21015 nodulation protein 0.26 UW163_RS15425 polyphosphate kinase 1 — —
Ralstonia sp. UNC404CL21Col 0.62 ABZR87_RS19020 multidrug efflux RND transporter permease subunit 0.28 ABZR87_RS14065 polyphosphate kinase 1 low > 80
Herbaspirillum seropedicae SmR1 0.61 HSERO_RS07655 nodulation protein 0.28 HSERO_RS06305 polyphosphate kinase low > 78
Acidovorax sp. GW101-3H11 0.56 Ac3H11_3620 Cobalt-zinc-cadmium resistance protein CzcA; Cation efflux system protein CusA 0.25 Ac3H11_452 Polyphosphate kinase (EC 2.7.4.1) 0.28 51
Pseudomonas fluorescens FW300-N2E3 0.55 AO353_22900 acriflavine resistance protein B 0.29 AO353_08885 polyphosphate kinase low > 101
Pseudomonas sp. S08-1 0.55 OH686_00930 Multidrug efflux system MdtABC-TolC, inner-membrane proton/drug antiporter MdtC (RND type) 0.29 OH686_13995 polyphosphate kinase 1 low > 80
Pseudomonas fluorescens GW456-L13 0.54 PfGW456L13_3265 Acriflavin resistance plasma membrane protein 0.29 PfGW456L13_874 Polyphosphate kinase (EC 2.7.4.1) low > 87
Pseudomonas syringae pv. syringae B728a ΔmexB 0.53 Psyr_2484 Acriflavin resistance protein 0.29 Psyr_0293 Polyphosphate kinase low > 86
Pseudomonas syringae pv. syringae B728a 0.53 Psyr_2484 Acriflavin resistance protein 0.29 Psyr_0293 Polyphosphate kinase low > 86
Pseudomonas stutzeri RCH2 0.53 Psest_2140 Cation/multidrug efflux pump 0.29 Psest_3732 polyphosphate kinase 1 low > 67
Pseudomonas fluorescens SBW25 0.53 PFLU_RS13435 MMPL family transporter 0.29 PFLU_RS29095 polyphosphate kinase 1 low > 109
Pseudomonas fluorescens SBW25-INTG 0.53 PFLU_RS13435 MMPL family transporter 0.29 PFLU_RS29095 polyphosphate kinase 1 low > 109
Rahnella sp. WP5 0.53 EX31_RS13375 MMPL family transporter 0.85 EX31_RS22680 polyphosphate kinase 1 low > 89
Pseudomonas putida KT2440 0.52 PP_3583 multidrug efflux transport system - membrane subunit 0.29 PP_5217 Polyphosphate kinase low > 96
Pseudomonas simiae WCS417 0.52 PS417_12750 acriflavine resistance protein B 0.29 PS417_27435 polyphosphate kinase low > 88
Castellaniella sp019104865 MT123 0.52 ABCV34_RS14625 efflux RND transporter permease subunit 0.24 ABCV34_RS15580 polyphosphate kinase 1 low > 48
Pseudomonas fluorescens FW300-N2E2 0.52 Pf6N2E2_1271 Acriflavin resistance plasma membrane protein 0.28 Pf6N2E2_4453 Polyphosphate kinase (EC 2.7.4.1) low > 103
Pseudomonas fluorescens FW300-N2C3 0.51 AO356_25880 acriflavine resistance protein B 0.28 AO356_12895 polyphosphate kinase low > 104
Pseudomonas sp. RS175 0.51 PFR28_02193 Multidrug resistance protein MdtC 0.28 PFR28_04345 Polyphosphate kinase low > 88
Rhodopseudomonas palustris CGA009 0.49 TX73_018025 multidrug efflux RND transporter permease subunit 0.27 TX73_015770 RNA degradosome polyphosphate kinase low > 86
Paraburkholderia sabiae LMG 24235 0.47 QEN71_RS29845 efflux RND transporter permease subunit 0.26 QEN71_RS04860 polyphosphate kinase 1 low > 153
Hydrogenophaga sp. GW460-11-11-14-LB1 0.46 GFF488 RND multidrug efflux transporter; Acriflavin resistance protein 0.23 GFF4226 Polyphosphate kinase (EC 2.7.4.1) low > 90
Paraburkholderia bryophila 376MFSha3.1 0.45 H281DRAFT_06491 multidrug efflux pump 0.26 H281DRAFT_04418 polyphosphate kinase low > 103
Azospirillum brasilense Sp245 0.44 AZOBR_RS14670 multidrug transporter 0.28 AZOBR_RS16235 polyphosphate kinase low > 97
Burkholderia phytofirmans PsJN 0.44 BPHYT_RS07780 nodulation protein 0.26 BPHYT_RS14110 polyphosphate kinase low > 109
Bosea sp. OAE506 0.41 ABIE41_RS20140 efflux RND transporter permease subunit 0.28 ABIE41_RS16125 RNA degradosome polyphosphate kinase low > 77
Agrobacterium fabrum C58 0.39 Atu3274 AcrB/AcrD/AcrF family protein 0.26 Atu1144 polyphosphate kinase — —
Variovorax sp. OAS795 0.39 ABID97_RS06490 efflux RND transporter permease subunit 0.24 ABID97_RS14575 polyphosphate kinase 1 low > 91
Rhizobium sp. OAE497 0.38 ABIE40_RS05760 efflux RND transporter permease subunit 0.27 ABIE40_RS06575 RNA degradosome polyphosphate kinase low > 107
Pontibacter actiniarum KMM 6156, DSM 19842 0.24 CA264_13040 acriflavin resistance protein 0.38 CA264_15725 polyphosphate kinase 1 low > 74
Acinetobacter radioresistens SK82 0.23 MPMX26_02516 Multidrug resistance protein MdtC 0.27 MPMX26_02335 Polyphosphate kinase low > 36
Sinorhizobium meliloti 1021 0.23 SMc01457 transport transmembrane protein 0.27 SMc00618 polyphosphate kinase low > 103
Caulobacter crescentus NA1000 Δfur 0.20 CCNA_03301 cation/multidrug efflux pump AcrB 0.27 CCNA_01782 polyphosphate kinase 1 low > 67
Caulobacter crescentus NA1000 0.20 CCNA_03301 cation/multidrug efflux pump AcrB 0.27 CCNA_01782 polyphosphate kinase 1 low > 66

Not shown: 3 genomes with orthologs for HEPCGN_02880 only; 36 genomes with orthologs for HEPCGN_20965 only