Conservation of cofitness between GFF2227 and GFF5307 in Sphingobium sp. HT1-2

61 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Sphingobium sp. HT1-2 1.0 GFF2227 D-mannonate oxidoreductase (EC 1.1.1.57) 1.0 GFF5307 FIG00883918: hypothetical protein 0.72 6
Brevundimonas sp. GW460-12-10-14-LB2 0.65 A4249_RS07740 mannitol dehydrogenase family protein 0.65 A4249_RS02835 MFS transporter low > 48
Bosea sp. OAE506 0.46 ABIE41_RS07815 mannitol dehydrogenase family protein 0.50 ABIE41_RS20905 MFS transporter low > 77
Variovorax sp. SCN45 0.45 GFF179 D-mannonate oxidoreductase (EC 1.1.1.57) 0.48 GFF5985 dicarboxylic acid transporter PcaT low > 127
Paraburkholderia bryophila 376MFSha3.1 0.44 H281DRAFT_02952 fructuronate reductase 0.46 H281DRAFT_05236 MFS transporter, MHS family, alpha-ketoglutarate permease low > 103
Burkholderia phytofirmans PsJN 0.43 BPHYT_RS28510 dioxygenase 0.48 BPHYT_RS27905 MFS transporter low > 109
Cupriavidus basilensis FW507-4G11 0.41 RR42_RS34965 dioxygenase 0.48 RR42_RS21430 alpha-ketoglutarate permease low > 128
Klebsiella michiganensis M5al 0.40 BWI76_RS19755 fructuronate reductase 0.46 BWI76_RS21415 MFS transporter low > 92
Enterobacter asburiae PDN3 0.40 EX28DRAFT_0389 Mannitol-1-phosphate/altronate dehydrogenases 0.49 EX28DRAFT_0060 metabolite-proton symporter low > 76
Klebsiella pneumoniae MKP103 0.40 KDGMDA_26695 fructuronate reductase 0.46 KDGMDA_28540 alpha-ketoglutarate transporter low > 95
Agrobacterium fabrum C58 0.40 Atu3530 mannitol dehydrogenase 0.69 Atu4017 MFS permease low > 89
Escherichia coli ECRC62 0.40 BNILDI_13910 yeiQ Uncharacterized oxidoreductase YeiQ 0.47 BNILDI_11775 kgtP alpha-ketoglutarate permease low > 75
Enterobacter sp. TBS_079 0.40 MPMX20_03138 Polyol:NADP oxidoreductase 0.49 MPMX20_03456 Alpha-ketoglutarate permease low > 85
Pantoea sp. MT58 0.40 IAI47_06820 mannitol dehydrogenase family protein 0.51 IAI47_04465 MFS transporter low > 76
Escherichia coli ECOR27 0.40 NOLOHH_14990 yeiQ Uncharacterized oxidoreductase YeiQ 0.47 NOLOHH_12970 kgtP alpha-ketoglutarate permease low > 76
Escherichia coli HS(pFamp)R (ATCC 700891) 0.40 OHPLBJKB_01537 Mannitol 2-dehydrogenase 0.47 OHPLBJKB_01119 Alpha-ketoglutarate permease low > 74
Escherichia coli BL21 0.40 ECD_02102 putative NAD-dependent D-mannonate oxidoreductase 0.47 ECD_02481 alpha-ketoglutarate transporter low > 61
Escherichia coli BW25113 0.40 b2172 yeiQ predicted dehydrogenase, NAD-dependent (NCBI) 0.47 b2587 kgtP alpha-ketoglutarate transporter (NCBI) low > 76
Escherichia coli Nissle 1917 0.40 ECOLIN_RS12705 mannitol dehydrogenase family protein 0.47 ECOLIN_RS14640 alpha-ketoglutarate permease low > 55
Escherichia coli ECRC99 0.40 KEDOAH_04770 yeiQ Uncharacterized oxidoreductase YeiQ 0.46 KEDOAH_06920 kgtP alpha-ketoglutarate permease — —
Escherichia coli ECRC100 0.40 OKFHMN_23415 yeiQ Uncharacterized oxidoreductase YeiQ 0.46 OKFHMN_21300 kgtP alpha-ketoglutarate permease low > 79
Escherichia coli ECOR38 0.40 HEPCGN_22680 yeiQ Uncharacterized oxidoreductase YeiQ 0.47 HEPCGN_20425 kgtP alpha-ketoglutarate permease low > 88
Escherichia coli ECRC101 0.40 MCAODC_14465 yeiQ Uncharacterized oxidoreductase YeiQ 0.46 MCAODC_11830 kgtP alpha-ketoglutarate permease low > 87
Escherichia coli ECRC98 0.40 JDDGAC_27375 yeiQ Uncharacterized oxidoreductase YeiQ 0.46 JDDGAC_24965 kgtP alpha-ketoglutarate permease low > 87
Escherichia coli ECRC102 0.40 NIAGMN_21180 yeiQ Uncharacterized oxidoreductase YeiQ 0.46 NIAGMN_19070 kgtP alpha-ketoglutarate permease low > 80
Escherichia fergusonii Becca 0.39 EFB2_01684 Mannitol 2-dehydrogenase 0.47 EFB2_01309 Alpha-ketoglutarate permease low > 86
Pantoea agglomerans CFBP13505 P0401 0.39 PagCFBP13505_RS00925 mannitol dehydrogenase family protein 0.51 PagCFBP13505_RS14455 MFS transporter low > 74
Dickeya dadantii 3937 0.39 DDA3937_RS14980 mannitol dehydrogenase family protein 0.46 DDA3937_RS16800 MFS transporter low > 74
Paraburkholderia graminis OAS925 0.38 ABIE53_005161 fructuronate reductase 0.49 ABIE53_002314 MHS family alpha-ketoglutarate permease-like MFS transporter low > 113
Dickeya dianthicola ME23 0.38 DZA65_RS03760 fructuronate reductase 0.47 DZA65_RS17945 MFS transporter low > 75
Serratia liquefaciens MT49 0.37 IAI46_17285 fructuronate reductase 0.48 IAI46_20040 MFS transporter low > 87
Dickeya dianthicola 67-19 0.37 HGI48_RS03640 fructuronate reductase 0.46 HGI48_RS16870 MFS transporter low > 71
Pectobacterium carotovorum WPP14 0.37 HER17_RS17590 fructuronate reductase 0.51 HER17_RS04420 MFS transporter low > 75
Rahnella sp. WP5 0.37 EX31_RS19095 fructuronate reductase 0.47 EX31_RS13690 MFS transporter low > 89
Pseudomonas fluorescens FW300-N2C3 0.36 AO356_28535 mannitol dehydrogenase 0.62 AO356_17790 alpha-ketoglutarate permease (MHS family) (from data) low > 104
Lysobacter sp. OAE881 0.36 ABIE51_RS03660 mannitol dehydrogenase family protein 0.62 ABIE51_RS02120 MFS transporter low > 62
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.36 GFF3094 D-mannonate oxidoreductase (EC 1.1.1.57) 0.48 GFF2093 Alpha-ketoglutarate permease low > 78
Caulobacter crescentus NA1000 Δfur 0.35 CCNA_01554 D-mannonate oxidoreductase 0.56 CCNA_01071 alpha-ketoglutarate permease low > 67
Caulobacter crescentus NA1000 0.35 CCNA_01554 D-mannonate oxidoreductase 0.56 CCNA_01071 alpha-ketoglutarate permease low > 66
Pseudomonas fluorescens FW300-N2E3 0.35 AO353_25900 mannitol dehydrogenase 0.62 AO353_03810 Alpha-ketoglutarate permease, MFS superfamily (from data) low > 101
Xanthomonas campestris pv. campestris strain 8004 0.35 Xcc-8004.5221.1 D-mannonate oxidoreductase (EC 1.1.1.57) 0.42 Xcc-8004.5310.1 dicarboxylate transport protein low > 74
Pseudomonas syringae pv. syringae B728a 0.35 Psyr_2436 Mannitol dehydrogenase 0.63 Psyr_3999 General substrate transporter:Major facilitator superfamily low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.35 Psyr_2436 Mannitol dehydrogenase 0.63 Psyr_3999 General substrate transporter:Major facilitator superfamily low > 86
Pseudomonas aeruginosa PA14 0.34 IKLFDK_11470 mannitol dehydrogenase 0.63 IKLFDK_25760 alpha-ketoglutarate permease low > 98
Pseudomonas aeruginosa MRSN321 0.34 DY961_RS18105 mannitol dehydrogenase family protein 0.63 DY961_RS25955 MFS transporter low > 100
Pseudomonas aeruginosa PUPa3 0.34 DQ20_RS59340 mannitol dehydrogenase family protein 0.63 DQ20_RS58380 MFS transporter low > 101
Pseudomonas orientalis W4I3 0.33 QF045_RS17200 mannitol dehydrogenase family protein 0.63 QF045_RS24820 MFS transporter low > 93
Pseudomonas sp. DMC3 0.33 GFF2899 Polyol:NADP oxidoreductase 0.61 GFF5042 Alpha-ketoglutarate permease low > 89
Pseudomonas lactucae CFBP13502 0.33 GEMAOFIL_02787 Polyol:NADP oxidoreductase 0.63 GEMAOFIL_04683 Alpha-ketoglutarate permease low > 96
Pseudomonas fluorescens FW300-N1B4 0.33 Pf1N1B4_4846 Multiple polyol-specific dehydrogenase (EC 1.1.1.-) 0.62 Pf1N1B4_686 Dicarboxylate MFS transporter low > 87
Pseudomonas fluorescens GW456-L13 0.33 PfGW456L13_3038 mannitol 2-dehydrogenase (EC 1.1.1.67) (from data) 0.62 PfGW456L13_1805 Dicarboxylate MFS transporter low > 87
Pseudomonas simiae WCS417 0.33 PS417_12695 mannitol dehydrogenase 0.63 PS417_22650 MFS transporter low > 88
Pseudomonas fluorescens SBW25 0.33 PFLU_RS13385 mannitol dehydrogenase family protein 0.63 PFLU_RS24285 MFS transporter low > 109
Pseudomonas fluorescens SBW25-INTG 0.33 PFLU_RS13385 mannitol dehydrogenase family protein 0.63 PFLU_RS24285 MFS transporter low > 109
Pseudomonas fluorescens FW300-N2E2 0.32 Pf6N2E2_806 Multiple polyol-specific dehydrogenase (EC 1.1.1.-) 0.62 Pf6N2E2_5486 Alpha-ketoglutarate permease (from data) low > 103
Pseudomonas sp. RS175 0.32 PFR28_01709 Polyol:NADP oxidoreductase 0.62 PFR28_03468 Alpha-ketoglutarate permease low > 88
Sphingomonas koreensis DSMZ 15582 0.30 Ga0059261_2975 Mannitol-1-phosphate/altronate dehydrogenases 0.75 Ga0059261_3091 Sugar (and other) transporter low > 68
Herbaspirillum seropedicae SmR1 0.21 HSERO_RS02215 D-arabinitol 4-dehydrogenase 0.48 HSERO_RS16820 2-oxoglutarate:H+ symporter (from data) low > 78
Ralstonia sp. UNC404CL21Col 0.21 ABZR87_RS18665 D-arabinitol 4-dehydrogenase 0.61 ABZR87_RS16295 MFS transporter low > 80
Paraburkholderia sabiae LMG 24235 0.20 QEN71_RS02630 mannitol dehydrogenase family protein 0.47 QEN71_RS07390 MFS family transporter low > 153
Pedobacter sp. GW460-11-11-14-LB5 0.15 CA265_RS19880 Altronate oxidoreductase (EC 1.1.1.58) (from data) 0.59 CA265_RS22390 alpha-ketoglutarate transporter low > 88
Mucilaginibacter yixingensis YX-36 DSM 26809 0.11 ABZR88_RS10495 tagaturonate reductase 0.57 ABZR88_RS05955 MFS transporter low > 71

Not shown: 12 genomes with orthologs for GFF2227 only; 18 genomes with orthologs for GFF5307 only